Human HAPLN4 Antibody

Catalog # Availability Size / Price Qty
MAB4085
MAB4085-SP
Product Details
Citations (1)
FAQs
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Human HAPLN4 Antibody Summary

Species Reactivity
Human
Specificity
Detects human HAPLN4 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human HAPLN1 is observed.
Source
Monoclonal Mouse IgG2B Clone # 387915
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
Mouse myeloma cell line NS0-derived recombinant human HAPLN4
Gln30-Val402 (predicted)
Accession # Q86UW8
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Applications

Recommended Concentration
Sample
Western Blot
1 µg/mL
Recombinant Human HAPLN4

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

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Preparation and Storage

Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS.
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Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: HAPLN4

Hyaluronan and Proteoglycan Link Protein 4, (HAPLN4), also known as brain link protein 2, is one of four secreted HAPLN family proteoglycans that bind hyaluronan. HAPLN4 contains one Ig-type C2-set domain and two link domains. It is predominantly expressed in brain and participates in the development of the perineuronal matrix. Human and mouse HAPLN4 share 91% aa sequence identity.

Long Name
Hyaluronan and Proteoglycan Link Protein 4
Entrez Gene IDs
404037 (Human); 330790 (Mouse)
Alternate Names
BRAL2; BRAL2KIAA1926Brain link protein 2; HAPLN4; hyaluronan and proteoglycan link protein 4; Lpr4

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Citation for Human HAPLN4 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

1 Citation: Showing 1 - 1

  1. Reduced expression of the hyaluronan and proteoglycan link proteins in malignant gliomas.
    Authors: Sim H, Hu B, Viapiano MS
    J. Biol. Chem., 2009-07-24;284(39):26547-56.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot

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