Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG
View all INSRR Primary Antibodies »

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant human INSRR
Leu24-Leu923
Accession # P14616

Specificity

Detects human INSRR in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 1% cross-reactivity with recombinant human INSR is observed.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications for Human INSRR Antibody

Application
Recommended Usage

Immunohistochemistry

5-15 µg/mL
Sample: Immersion fixed paraffin-embedded sections of human brain (cortex) subjected to Antigen Retrieval Reagent-Basic (Catalog # CTS013)

Western Blot

0.1 µg/mL
Sample: Recombinant Human INSRR

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Background: INSRR

INSRR is a 175 kDa orphan receptor belonging to the insulin receptor subfamily of the receptor tyrosine kinase family. It is synthesized as a single chain type I transmembrane glycoprotein precursor and undergoes proteolytic processing to generate the mature disulfide linked alpha 2/ beta 2 tetrameric receptor. The alpha subunit is localized extracellularly while the transmembrane beta subunit contains an extracellular domain, a transmembrane segment and a cytoplasmic kinase domain. A ligand for INSRR has not yet been identified. The extracellular domain of human INSRR shares approximately 90% amino acid sequence homology with the mouse protein.

Long Name

Insulin Receptor-related Receptor

Alternate Names

IRR

Entrez Gene IDs

3645 (Human); 23920 (Mouse)

Gene Symbol

INSRR

UniProt

P14616

Additional INSRR Products

Product Documents for Human INSRR Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Note: Certificate of Analysis not available for kit components.

Download SDS

Product Specific Notices for Human INSRR Antibody

For research use only

Customer Reviews for Human INSRR Antibody

There are currently no reviews for this product. Be the first to review Human INSRR Antibody and earn rewards!

Have you used Human INSRR Antibody?

Submit a review and receive an Amazon gift card!

$25/€18/£15/$25CAN/¥2500 Yen for a review with an image

$10/€7/£6/$10CAN/¥1110 Yen for a review without an image

Submit a review
Amazon Gift Card

Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs

No product specific FAQs exist for this product.

View all FAQs for Antibodies