Human LPAR1/LPA1/EDG-2 Antibody

Catalog # Availability Size / Price Qty
LPAR1/LPA1/EDG-2 in Human Prostate Cancer Tissue.
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Human LPAR1/LPA1/EDG-2 Antibody Summary

Species Reactivity
Detects human LPAR1/LPA1/EDG-2 in direct ELISAs.
Monoclonal Mouse IgG1 Clone # 999807
Protein A or G purified from hybridoma culture supernatant
E. coli-derived recombinant human LPAR1/LPA1/EDG-2
Accession # Q92633
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.


Recommended Concentration
5-25 µg/mL
See below

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Immunohistochemistry LPAR1/LPA<sub>1</sub>/EDG-2 antibody in Human Prostate Cancer Tissue by Immunohistochemistry (IHC-P). View Larger

LPAR1/LPA1/EDG-2 in Human Prostate Cancer Tissue. LPAR1/LPA1/EDG-2 was detected in immersion fixed paraffin-embedded sections of human prostate cancer tissue using Mouse Anti-Human LPAR1/LPA1/EDG-2 Monoclonal Antibody (Catalog # MAB9963) at 5 µg/mL for 1 hour at room temperature followed by incubation with the Anti-Mouse IgG VisUCyte™ HRP Polymer Antibody (Catalog # VC001). Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic (Catalog # CTS013). Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to cell surfaces and cytoplasm in cancer cells. View our protocol for IHC Staining with VisUCyte HRP Polymer Detection Reagents.

Reconstitution Calculator

Reconstitution Calculator

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Preparation and Storage

Reconstitute at 0.5 mg/mL in sterile PBS.
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: LPAR1/LPA1/EDG-2

Lysophosphatidic acid receptor 1, LPAR1, also known as EDG-2, is a G protein-coupled receptor that binds the lipid signaling molecule lysophosphatidic acid (LPA). EDG molecules are G protein-coupled receptors that bind plasma lysophospholipids. The EDG family consists of two subfamilies; the S1P (sphingosine-1-phosphate) subfamily consisting of EDG-1, 3, 5, 6, and 8, and the LPA subfamily that contains EDG-2, 4 and 7. The S1P family regulates essential cellular processes such as proliferation, migration, cytoskeletal organization, and differentiation.

Long Name
Lysophosphatidic Acid Receptor 1
Entrez Gene IDs
1902 (Human); 14745 (Mouse)
Alternate Names
EDG2; edg-2; EDG2Lysophosphatidic acid receptor Edg-2; endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor2,; GPCR26; GPR26; LPA receptor 1; LPA1; LPA-1; LPA1vzg-1; LPAR1; lysophosphatidic acid receptor 1; Mrec1.3; rec.1.3; ventricular zone gene 1; VZG1; vzg-1

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Human LPAR1/LPA1/EDG-2 Antibody
By Anonymous on 10/14/2022
Application: IHC Sample Tested: Prostate tissue Species: Human