Human MSP alpha Chain Antibody
Human MSP alpha Chain Antibody Summary
Accession # AAA59872
under non-reducing conditions only
Human MSP Sandwich Immunoassay
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
MSP, also known as hepatocyte growth factor-like protein (HGFl), and scatter factor-2 (SF2), is a member of the HGF family of growth factors. It is secreted as a single chain inactive precursor which is proteolytically activated to yield a biologically active disulfide-linked heterodimer of the alpha and beta chains. MSP induces keratinocyte proliferation, bone resorption, and cell migration and shape change in resident macrophages. Heterodimeric MSP binds to and activates the cell surface receptor tyrosine kinase, RON/STK, which is expressed on mature macrophages, keratinocytes, and vascular endothelium of wounded skin.
Citations for Human MSP alpha Chain Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
Citations: Showing 1 - 2
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HIV?1 downregulates the expression and phosphorylation of receptor tyrosine kinase by targeting the NF??B pathway
Mol Med Rep, 2016;0(0):.
Sample Types: Whole Blood
Applications: ELISA Development (Capture)
Functional consequences of the macrophage stimulating protein 689C inflammatory bowel disease risk allele.
Authors: Kauder, Steven E, Santell, Lydia, Mai, Elaine, Wright, Lilyan Y, Luis, Elizabet, N'Diaye, Elsa N, Lutman, Jeff, Ratti, Navneet, Sa, Susan M, Maun, Henry R, Stefanich, Eric, Gonzalez, Lino C, Graham, Robert R, Diehl, Lauri, Faubion, William, Keir, Mary E, Young, Judy, Chaudhuri, Amitabha, Lazarus, Robert A, Egen, Jackson
PLoS ONE, 2013;8(12):e83958.
Sample Types: Serum
Applications: ELISA Development
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Average Rating: 4 (Based on 1 Review)
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We used this antibody for developing a sandwich ELISA in combination with protein (352-MS) and pAb (AF352). This combination worked well and detected human MSP in serum samples efficiently.