Human MSP beta Chain Antibody
Human MSP beta Chain Antibody Summary
Accession # P26927
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
MSP, also known as hepatocyte growth factor-like protein (HGFl), and scatter factor-2 (SF2), is a member of the HGF family of growth factors. It is secreted as a single chain inactive precursor which is proteolytically activated to yield a biologically active disulfide-linked heterodimer of the alpha and beta chains. MSP induces keratinocyte proliferation, bone resorption, and cell migration and shape change in resident macrophages. Heterodimeric MSP binds to and activates the cell surface receptor tyrosine kinase, RON/STK, which is expressed on mature macrophages, keratinocytes, and vascular endothelium of wounded skin.
Citations for Human MSP beta Chain Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
Citations: Showing 1 - 2
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RON kinase inhibition reduces renal endothelial injury in sickle cell disease mice
Authors: A Khaibullin, EA Adjei, N Afangbedji, A Ivanov, N Kumari, LEF Almeida, ZMN Quezado, S Nekhai, M Jerebtsova
Sample Types: Whole Tissue
Macrophage-stimulating protein differently affects human alveolar macrophages from smoker and non-smoker patients: evaluation of respiratory burst, cytokine release and NF-kappaB pathway.
Authors: Gunella G, Bardelli C, Amoruso A
Br. J. Pharmacol., 2006-04-24;148(4):478-89.
Sample Types: Whole Cells
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