Human OSCAR Antibody

Catalog # Availability Size / Price Qty
MAB2004
MAB2004-SP

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Product Details
Citations (1)
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Human OSCAR Antibody Summary

Species Reactivity
Human
Specificity
Detects human OSCAR in direct ELISAs and Western blots. In Western blots, this antibody does not cross-react with recombinant mouse OSCAR.
Source
Monoclonal Mouse IgG2B Clone # 259501
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
Mouse myeloma cell line NS0-derived recombinant human OSCAR isoform 2
Asp19-Asn229 (Asn158Ser)
Accession # Q8IYS5
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Applications

Recommended Concentration
Sample
Western Blot
1 µg/mL
Recombinant Human OSCAR

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS.
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Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: OSCAR

OSCAR is a type I membrane protein that belongs to the leukocyte receptor complex (LRC) protein family. It is expressed specifically in preosteoclasts and mature osteoclasts. OSCAR may be an important regulator of osteoclast differentiation.

Long Name
Osteoclast-associated Receptor
Entrez Gene IDs
126014 (Human); 232790 (Mouse)
Alternate Names
hOSCAR; MGC33613; OSCAR; osteoclast associated receptor OSCAR-S1; osteoclast associated receptor OSCAR-S2; osteoclast associated, immunoglobulin-like receptor; osteoclast-associated immunoglobulin-like receptor; Osteoclast-associated receptor; PIGR3; PIgR-3; Poly-Ig receptor 3; Polymeric immunoglobulin receptor 3

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Citation for Human OSCAR Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

1 Citation: Showing 1 - 1

  1. Induction of osteoclast-associated receptor, a key osteoclast costimulation molecule, in rheumatoid arthritis.
    Authors: Herman S, Muller RB, Kronke G, Zwerina J, Redlich K, Hueber AJ, Gelse H, Neumann E, Muller-Ladner U, Schett G
    Arthritis Rheum., 2008-10-01;58(10):3041-50.
    Species: Human
    Sample Types: Serum
    Applications: ELISA Development

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