Human Pannexin-2 Antibody

Catalog # Availability Size / Price Qty
Detection of Human Pannexin‑2 by Western Blot.
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Product Details
Supplemental Products

Human Pannexin-2 Antibody Summary

Species Reactivity
Detects human Pannexin-2 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 5% cross-reactivity with recombinant human (rh) Pannexin-1 and no cross-reactivity with rhPannexin-3 is observed.
Monoclonal Mouse IgG2B Clone # 719406
Protein A or G purified from hybridoma culture supernatant
E. coli-derived recombinant human Pannexin-2
Accession # Q96RD6
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.


Recommended Concentration
Western Blot
0.5 µg/mL
See below

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Data Example

Western Blot Detection of Human Pannexin-2 antibody by Western Blot. View Larger

Detection of Human Pannexin‑2 by Western Blot. Western blot shows lysates of human brain (cortex) tissue and human brain (hippocampus) tissue. PVDF membrane was probed with 0.5 µg/mL of Mouse Anti-Human Pannexin-2 Monoclonal Antibody (Catalog # MAB7088) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF007). A specific band was detected for Pannexin-2 at approximately 65 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

Reconstitution Calculator

Reconstitution Calculator

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Preparation and Storage

Sterile PBS to a final concentration of 0.5 mg/mL.
Reconstitution Buffer Available
Reconstitution Buffer 1 (PBS)
Catalog #
Size / Price
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Pannexin-2

Pannexin 2 (PANX2) is a ~60 kDa, 677 amino acid (aa) protein of the pannexin family of four-transmembrane channel proteins with a conserved pattern of cysteines. PANX2 can interact with PANX1. It is mainly expressed on postnatal neural progenitors and is thought to inhibit the rate of neuronal differentiation. PANX2 expression is positively correlated with survival following glioma diagnosis, and it negatively regulates glioma cell line growth. Polymorphisms of PANX2 are associated with bipolar disorder and schizophrenia. Within aa 316‑456, human PANX2 shares 96% aa sequence identity with mouse and rat PANX2. A 643 aa isoform diverges after aa 631, while a 509 aa isoform also shows an alternate start site at aa 135.

Entrez Gene IDs
56666 (Human); 406218 (Mouse); 362979 (Rat)
Alternate Names
hPANX2; MGC119432; pannexin 2; Pannexin2; Pannexin-2; PANX2; PX2

Product Datasheets


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Isotype Controls

Reconstitution Buffers

Secondary Antibodies

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