Human RAR gamma /NR1B3 Antibody

R&D Systems | Catalog # PP-H5620-00

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Key Product Details

Species Reactivity

Human

Applications

Western Blot, Direct ELISA, Immunoprecipitation

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2A Clone # H5620
View all RAR gamma/NR1B3 Primary Antibodies »

Product Specifications

Immunogen

Recombinant human RAR gamma/NR1B3

Specificity

This antibody specifically recognizes human RAR gamma and does not cross-react with human RAR alpha or RAR beta. Not yet tested in other species.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Applications for Human RAR gamma /NR1B3 Antibody

Application
Recommended Usage

Direct ELISA

This antibody can be used at 60 ng/mL with the appropriate secondary reagents to detect human RAR gamma.

Immunoprecipitation

Optimal dilutions should be determined by each laboratory.

Western Blot

This antibody can be used at 1 μg/mL under reducing conditions with the appropriate secondary reagents to detect human RAR gamma.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

A liquid formulation in physiologic saline with 0.1% NaN3.

Shipping

The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

This antibody is stable for greater than six months when held at -20 °C in a manual defrost freezer or at -70 °C. Upon thawing, the antibody can be stored at 2-8 °C for at least 1 month without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Background: RAR gamma/NR1B3

Retinoic Acid Receptor gamma (RAR gamma ; NR1B3) is closely related to the Thyroid hormone Receptor (TR). RARs bind to two retinoids, all-trans retinoic acid and 9-cis retinoic acid. RAR gamma is expressed in both adult and fetal skin. Along with other members of the RAR family, RAR gamma is redundantly involved in vertebrates in the pleiotropic control of embryonic patterning and organogenesis, cell proliferation, differentiation and apoptosis, as well as homeostatic control.

Long Name

Retinoic Acid Receptor, gamma

Alternate Names

NR1B3, RARC, RARG

Entrez Gene IDs

5916 (Human)

Gene Symbol

RARG

Additional RAR gamma/NR1B3 Products

Product Documents for Human RAR gamma /NR1B3 Antibody

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Human RAR gamma /NR1B3 Antibody

For research use only

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