Human Serpin A3/ alpha 1-Antichymotrypsin Antibody

Catalog # Availability Size / Price Qty
Product Details
Citations (3)
Supplemental Products

Human Serpin A3/ alpha 1-Antichymotrypsin Antibody Summary

Species Reactivity
Detects recombinant human (rh)Serpin A3 in direct ELISAs and Western blots. In these formats, this antibody shows 5 - 25% cross-reactivity with rhSerpins A1 and A5 but no cross-reactivity with rhSerpins C1, D1, or F2.
Monoclonal Mouse IgG2A Clone # 213907
Protein A or G purified from hybridoma culture supernatant
Mouse myeloma cell line NS0-derived recombinant human Serpin A3
aa 26-423
Accession # P01011
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.


Recommended Concentration
Western Blot
1 µg/mL
Recombinant Human Serpin A3/ alpha 1-Antichymotrypsin (Catalog # 1295-PI)

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

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Preparation and Storage

Reconstitute at 0.5 mg/mL in sterile PBS.
Reconstitution Buffer Available
Reconstitution Buffer 1 (PBS)
Catalog #
Size / Price
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Serpin A3/alpha 1-Antichymotrypsin

Serpin A3, also called alpha 1-Antichymotrypsin, is a major constituent of the plaques associated with Alzheimer’s disease. Deficiency in Serpin A3 activity is associated with chronic obstructive pulmonary disease.

Entrez Gene IDs
12 (Human)
Alternate Names
AACTMGC88254; ACTGIG25; alpha 1-Antichymotrypsin; alpha-1-antichymotrypsin; antitrypsin), member 3; Cell growth-inhibiting gene 24/25 protein; growth-inhibiting protein 24; growth-inhibiting protein 25; member 3; serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase; serine (or cysteine) proteinase inhibitor, clade A, member 3; Serpin A3; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin)

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Citations for Human Serpin A3/ alpha 1-Antichymotrypsin Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

3 Citations: Showing 1 - 3
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  1. Aberrant upregulation of the glycolytic enzyme PFKFB3 in CLN7 neuronal ceroid lipofuscinosis
    Authors: I Lopez-Fabu, M Garcia-Mac, C Buondelmon, O Burmistrov, N Bonora, P Alonso-Bat, B Morant-Fer, C Vicente-Gu, D Jimenez-Bl, R Quintana-C, E Fernandez, J Llop, P Ramos-Cabr, A Sharaireh, M Guevara-Fe, L Fitzpatric, CD Thompton, TR McKay, S Storch, DL Medina, SE Mole, PO Fedichev, A Almeida, JP Bolaños
    Nature Communications, 2022;13(1):536.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  2. Drug library screen identifies inhibitors of toxic astrogliosis
    Authors: R Masvekar, P Kosa, C Barbour, JL Milstein, B Bielekova
    Multiple sclerosis and related disorders, 2022;58(0):103499.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  3. Maggot chymotrypsin I from Lucilia sericata is resistant to endogenous wound protease inhibitors.
    Authors: Telford G, Brown AP, Kind A, English JS, Pritchard DI
    Br. J. Dermatol., 2011;164(1):192-6.
    Species: Human
    Sample Types: Tissue Homogenates
    Applications: Western Blot


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Isotype Controls

Mouse IgG2A Isotype Control

Reconstitution Buffers

Secondary Antibodies

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