SLC22A2 in Human Kidney.
SLC22A2 was detected in immersion fixed paraffin-embedded sections of human kidney using Human SLC22A2 Monoclonal Antibody (Catalog # MAB6547) at 25 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Mouse HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS002) and counterstained with hematoxylin (blue). Specific staining was localized to the cytoplasm of epithelial cells in convoluted tubules. View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections.
Preparation and Storage
Sterile PBS to a final concentration of 0.5 mg/mL.
Reconstitution Buffer Available
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.
Solute carrier family 22 member 2 (SLC22A2; also hOCT2) is a
65 kDa member of the major facilitator superfamily and organic cation
transporter family of proteins. Human
SLC22A2 is synthesized as a multipass transmembrane protein that is 555 amino
acids (aa) in length.
Human SLC22A2 contains one potential site for N-linked
glycosylation. There are also two
additional isoforms for human SLC22A2.
Isoform 2 has a 57 aa substitution for aa 427-483 and a deletion of the
72 aa at positions 484-555. Isoform 3
has an 18 aa substitution for aa 225-242 and a deletion of residues
243-555. SLC22A2 has its highest
expression in the kidney. It is also
expressed at lower levels in neurons of the cerebral cortex and in various subcortical
Organic Cation Transporter 2
Entrez Gene IDs:
6582 (Human); 29503 (Rat)
hOCT2; MGC32628; OCT2; OCT2Organic cation transporter 2; SLC22A2; solute carrier family 22 (organic cation transporter), member 2; solute carrier family 22 member 2
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