Human TLX/NR2E1 Antibody (H6506)

R&D Systems | Catalog # PP-H6506-00

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Key Product Details

Species Reactivity

Human

Applications

Western Blot, Direct ELISA, Immunoprecipitation

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2A Clone # H6506
View all TLX/NR2E1 Primary Antibodies »

Product Specifications

Immunogen

Recombinant human TLX/NR2E1

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Scientific Data Images for Human TLX/NR2E1 Antibody (H6506)

Detection of Human TLX/NR2E1 by Immunohistochemistry

Detection of Human TLX/NR2E1 by Immunohistochemistry

TLX is expressed strongly in NB tissues and correlates with poor survival. (a) Low magnification ( × 1) of the whole tissue array stained for TLX. Identity of tissues is described below. Representative photomicrographs of normal peripheral nerve tissue and NB tissue in tissue array are immunostained for TLX (brown) and then counterstained with light green. Magnification, × 40. (b) Kaplan–Meier analysis of the data from 88 cases of NB, indicating negative correlation of NR2E1 expression with survival Image collected and cropped by CiteAb from the following publication (https://www.nature.com/articles/cddis2014449), licensed under a CC-BY license. Not internally tested by R&D Systems.

Applications for Human TLX/NR2E1 Antibody (H6506)

Application
Recommended Usage

Direct ELISA

Optimal dilutions of this antibody should be experimentally determined.

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Formulation

A liquid formulation in physiologic saline with 0.1% NaN<sub>3</sub>.

Shipping

The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store the unopened product at -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: TLX/NR2E1

Orphan receptor that binds DNA as a monomer to hormone response elements (HRE) containing an extended core motif half-site sequence 5'-AAGGTCA-3' in which the 5' flanking nucleotides participate in determining receptor specificity. May be required for brain development. May be involved in the regulation of retinal development (By similarity)

Long Name

Tailless Homolog [Drosophila]

Alternate Names

NR2E1, TLL

Entrez Gene IDs

7101 (Human)

Gene Symbol

NR2E1

Additional TLX/NR2E1 Products

Product Documents for Human TLX/NR2E1 Antibody (H6506)

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Human TLX/NR2E1 Antibody (H6506)

For research use only

Citations for Human TLX/NR2E1 Antibody (H6506)

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FAQs

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