Human TRIM38 Antibody

Catalog # Availability Size / Price Qty
Detection of Human TRIM38 by Western Blot.
2 Images
Product Details
Supplemental Products

Human TRIM38 Antibody Summary

Species Reactivity
Detects human TRIM38 in direct ELISAs and Western blots.
Polyclonal Goat IgG
Antigen Affinity-purified
E.coli-derived recombinant human TRIM38
Accession # O00635
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.


Recommended Concentration
Western Blot
2 µg/mL
See below
5-15 µg/mL
See below

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Western Blot Detection of Human TRIM38 antibody by Western Blot. View Larger

Detection of Human TRIM38 by Western Blot. Western blot shows lysates of RT-4 human bladder carcinoma cell line, HeLa human cervical epithelial carcinoma cell line, A431 human epithelial carcinoma cell line, Jurkat human acute T cell leukemia cell line, and MCF-7 human breast cancer cell line. PVDF membrane was probed with 2 µg/mL of Goat Anti-Human TRIM38 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF9104) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF017). A specific band was detected for TRIM38 at approximately 50 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

Immunohistochemistry TRIM38 antibody in Human Lymph Node by Immunohistochemistry (IHC-P). View Larger

TRIM38 in Human Lymph Node. TRIM38 was detected in immersion fixed paraffin-embedded sections of human lymph node using Goat Anti-Human TRIM38 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF9104) at 10 µg/mL for 1 hour at room temperature followed by incubation with the Anti-Goat IgG VisUCyte™ HRP Polymer Antibody (Catalog # VC004). Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to cytoplasm. View our protocol for IHC Staining with VisUCyte HRP Polymer Detection Reagents.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.


Preparation and Storage

Reconstitute at 0.2 mg/mL in sterile PBS.
Reconstitution Buffer Available
Reconstitution Buffer 1 (PBS)
Catalog #
Size / Price
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: TRIM38

Human Tripartite Motif 38 (TRIM38, RNF15) is a 465 aminoacids E3 ubiquitin ligase that plays a key role in tuning TLR-mediated immune responses by selectively targeting molecules in the TLR signaling for proteasomal degradation. The TRIM family of E3 ligases has more than 70 members in humans. Many members of this protein family are important immune regulators, mediating innate immune cell signal transduction and subsequent cytokine induction immune regulation. Trim38 deficiency, for example, greatly increases TLR3- and TLR4-mediated induction of type I Interferons and proinflammatory cytokines, such as TNF-alpha, IL-1 beta, and IL-6, in immune cells and in vivo.

Long Name
Tripartite Motif-containing 38
Entrez Gene IDs
10475 (Human); 214158 (Mouse); 680019 (Rat)
Alternate Names
MGC8946; RING finger protein 15RORETRo/SSA ribonucleoprotein homolog; RNF15; RoRet; TRIM38; tripartite motif containing 38; tripartite motif-containing 38; tripartite motif-containing protein 38; Zinc finger protein RoRet; zinc-finger protein RoRet

Product Datasheets

You must select a language.



No product specific FAQs exist for this product, however you may

View all Antibody FAQs

Isotype Controls

Reconstitution Buffers

Secondary Antibodies

Reviews for Human TRIM38 Antibody

There are currently no reviews for this product. Be the first to review Human TRIM38 Antibody and earn rewards!

Have you used Human TRIM38 Antibody?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review