Mouse Neuregulin-3/NRG3 EGF-like Domain Antibody

Catalog # Availability Size / Price Qty
Neuregulin‑3/NRG3 in Mouse Brain.
1 Image
Product Details
Citations (1)
Supplemental Products

Mouse Neuregulin-3/NRG3 EGF-like Domain Antibody Summary

Species Reactivity
Detects mouse NRG3 EGF-like domain in direct ELISAs and Western blots.
Polyclonal Goat IgG
Antigen Affinity-purified
Mouse myeloma cell line NS0-derived recombinant mouse NRG3
Accession # O35181
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.


Recommended Concentration
Western Blot
0.1 µg/mL
Recombinant Mouse Neuregulin‑3/NRG3 EGF-like Domain
5-15 µg/mL
See below

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Immunohistochemistry Neuregulin-3/NRG3 antibody in Mouse Brain by Immunohistochemistry (IHC-Fr). View Larger

Neuregulin‑3/NRG3 in Mouse Brain. Neuregulin-3/NRG3 was detected in perfusion fixed frozen sections of mouse brain (hippocampus) using Goat Anti-Mouse Neuregulin-3/NRG3 EGF-like Domain Antigen Affinity-purified Polyclonal Antibody (Catalog # AF753) at 5 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS008) and counterstained with hematoxylin (blue). Specific staining was localized to cell bodies and neuronal processes. View our protocol for Chromogenic IHC Staining of Frozen Tissue Sections.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.


Preparation and Storage

Reconstitute at 0.2 mg/mL in sterile PBS.
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Neuregulin-3/NRG3

The neuregulin (also known as heregulin) cytokine family is comprised of four genes that encode a large number of secreted or membrane-bound isoforms. All family members share an EGF-like domain that interacts with the ErbB family of tyrosine kinase receptors. The NRG1 gene is the most pleiotropic, encoding more than 14 soluble or transmembrane proteins. NRG1 isoforms can be classified into type I (neu differentiation factor, NDF; heregulin, HRG; acetylcholine receptor inducing activity, ARIA), type II (glial growth factor, GGF) and type III (sensory and motor neuron-derived factor, SMDF) isoforms. NRG proteins show distinct spatial and temporal expression patterns and play important roles during development of both the nervous system and the heart.

Entrez Gene IDs
10718 (Human); 18183 (Mouse)
Alternate Names
HRG3; neuregulin 3 variant 1; neuregulin 3 variant 10; neuregulin 3 variant 11; neuregulin 3 variant 12; neuregulin 3 variant 13; neuregulin 3 variant 14; neuregulin 3 variant 3; neuregulin 3 variant 4; neuregulin 3 variant 5; neuregulin 3 variant 6; neuregulin 3 variant 7; neuregulin 3 variant 8; neuregulin 3 variant 9; neuregulin 3; Neuregulin3; Neuregulin-3; neuregulin-3-like polypeptide; NRG3; pro-neuregulin-3, membrane-bound isoform; pro-NRG3

Product Datasheets

You must select a language.


Citation for Mouse Neuregulin-3/NRG3 EGF-like Domain Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

1 Citation: Showing 1 - 1

  1. Dynamic expression of Erbb pathway members during early mammary gland morphogenesis.
    Authors: Wansbury O, Panchal H, James M, Parry S, Ashworth A, Howard B
    J. Invest. Dermatol., 2007-10-25;128(4):1009-21.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P


No product specific FAQs exist for this product, however you may

View all Antibody FAQs

Reviews for Mouse Neuregulin-3/NRG3 EGF-like Domain Antibody

There are currently no reviews for this product. Be the first to review Mouse Neuregulin-3/NRG3 EGF-like Domain Antibody and earn rewards!

Have you used Mouse Neuregulin-3/NRG3 EGF-like Domain Antibody?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review