14 results for "alpha-1B Adrenergic R/ADRA1B" in Products

alpha-1B Adrenergic R/ADRA1B Products

ADRA1B, also known as the alpha-1B-adrenergic receptor, is a 7TM catecholamine receptor with selectivity for epinephrine and norepinephrine. ADRA1B functions in diverse settings including vasoconstriction and myocardial contractility, neuronal dopaminergic responses, dendritic cell migration and inflammatory responses, and neuroendocrine regulation of fertility.

GluN2B-selective NMDA antagonist

Chemical Name: RS)-α-(4-Hydroxyphenyl)-β-methyl-4-(phenylmethyl)-1-piperidinepropanol maleate
Purity: ≥98%
GluN2B-selective NMDA antagonist
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α1 and α2B antagonist; also MT3 antagonist

Chemical Name: 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-furanylcarbonyl)piperazine hydrochloride
Purity: ≥98%
α1 and α2B antagonist; also MT3 antagonist
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Dopamine antagonist with some D4 selectivity; also 5-HT2A/2C antagonist

Chemical Name: 8-Chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo[b,e][1,4]diazepine
Purity: ≥98%
Dopamine antagonist with some D4 selectivity; also 5-HT2A/2C antagonist
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Dopamine antagonist; displays some D2 selectivity

Chemical Name: 4-[4-(4-Chlorophenyl)-4-hydroxy-1-piperidinyl]-1-(4-fluorophenyl)-1-butanone hydrochloride
Purity: ≥98%
Dopamine antagonist; displays some D2 selectivity
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α1 antagonist; PGK1 activator

Chemical Name: 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-[(tetrahydro-2-furanyl)carbonyl]-piperazine hydrochloride
Purity: ≥98%
α1 and α2B antagonist (α1 > α2B). Orally active
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Highly selective α1 antagonist

Alternate Names: BE 2254
Chemical Name: 2-{[β-(4-Hydroxyphenyl)ethyl]aminomethyl}-1-tetralone hydrochloride
Purity: ≥98%
Highly selective α1 antagonist
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Potent and non-selective β antagonist; also potent α1 antagonist

Alternate Names: BM 14190
Chemical Name: 1-(9H-Carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-2-propanol
Purity: ≥98%
Potent and non-selective β antagonist; also potent α1 antagonist
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α1 antagonist

Alternate Names: UK 33274
Chemical Name: 4-Amino-2-[4-(1,4-benzodioxan-2-carbonyl)piperazin-1-yl]-6,7-dimethoxyquinazoline methanesulfonate
Purity: ≥98%
Reduced viability of differentiated cardiomyocytes exposed to cardiotoxic small molecules
(2)
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Potent and selective α2 antagonist

Chemical Name: 6-Chloro-N-methyl-2,3,4,5-tetrahydro-1-H-3-benzazepine hydrochloride
Purity: ≥98%
Potent and selective α2 antagonist
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Selective α1A antagonist

Chemical Name: 5-[(2R)-2-[[2-(2-Ethoxyphenoxy)ethyl]amino]propyl]-2-methoxybenzenesulfonamide hydrochloride
Purity: ≥98%
Selective α1A antagonist
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Non-selective 5-HT, dopamine, adrenalin and histamine receptor antagonist; antipsychotic agent

Chemical Name: (3aR*,12bR*)-5-Chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrole maleate
Purity: ≥98%
Non-selective 5-HT, dopamine, adrenalin and histamine receptor antagonist; antipsychotic agent
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5-HT2A antagonist; also D2 antagonist; atypical antipsychotic

Chemical Name: 2-Methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5]benzodiazepine
Purity: ≥98%
5-HT2A antagonist; also D2 antagonist; atypical antipsychotic
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5-HT2 antagonist; also D2 antagonist; atypical antipsychotic

Alternate Names: ICI 204,636
Chemical Name: 2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol hemifumarate
Purity: ≥98%
5-HT2 antagonist; also D2 antagonist; atypical antipsychotic
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Adrenergic α receptor antagonist; antihypertensive

Chemical Name: 3-[[(4,5-Dihydro-1H-imidazol-2-yl)methyl](4-methylphenyl)amino]phenol methanesulfonate
Purity: ≥98%
Adrenergic α receptor antagonist; antihypertensive
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