284 results for "IGFBP-3" in Products
IGFBP-3 Products
IGFBP-3 (Insulin-like growth factor binding protein-3) modulates the biological activity of IGF. It circulates in a ternary complex with IGF and the acid-labile subunit (ALS). Proteolysis of IGFBP-3 by tissue plasminogen activator (tPA), a disintegrin and metalloproteases (ADAMs), and prostate specific antigen (PSA) contributes to IGFBP-3 degradation or a reduction in its affinity for IGF. The majority of soluble IGFBP-3 found in circulation is secreted from hepatic non-parenchymal cells. IGFBP-3 potentiates EGF-EGFR-mediated cell growth, modulates adipogenesis, and regulates TGF-beta signaling, DNA damage, apoptosis, autophagy, and gene transcription.
Human Luminex® Discovery Assay Best Seller
| Reactivity: | Human |
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| Reactivity: | Human |
| Sensitivity: | 0.14 ng/mL |
| Assay Range: | 0.781-50 ng/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma) |
| Applications: | ELISA |
| Reactivity: | Mouse |
| Sensitivity: | 16 pg/mL |
| Assay Range: | 78.1-5000 pg/mL (Cell Culture Supernates, EDTA Plasma) |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | IHC, WB, B/N |
| Reactivity: | Human |
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #84728 |
| Applications: | IHC, WB, ELISA(Cap) |
| Reactivity: | Mouse |
| Reactivity: | Human |
| Source: | NS0 |
| Accession #: | CAA46087 |
| Applications: | Bioactivity |
| Reactivity: | Human |
| Reactivity: | Human |
| Assay Range: | 125-8000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Mouse |
| Source: | NS0 |
| Accession #: | CAA57271.1 |
| Applications: | Bioactivity |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Simple Western |
| Reactivity: | Mouse |
| Details: | Rat IgG2B Monoclonal Clone #138202 |
| Applications: | WB, ELISA(Cap) |
| Reactivity: | Mouse |
| Assay Range: | 62.5-4000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Mouse IgG2 Monoclonal Clone #MM0342-6U23 |
| Applications: | IHC, WB |
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #1065833 |
| Applications: | IHC, ICC/IF |
| Chemical Name: | 1-(3,4-Dihydroxybenzoyl)-6,7-dihydroxy-3-isoquinolinecarboxylic acid |
| Purity: | ≥98% |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB |
![Immunohistochemistry-Frozen: IGFBP-3 Antibody [NBP2-16933]](https://resources.rndsystems.com/images/products/IGFBP-3-Antibody-Immunohistochemistry-Frozen-NBP2-16933-img0002.jpg "Immunohistochemistry-Frozen: IGFBP-3 Antibody [NBP2-16933]")
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ELISA(Det) |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ELISA(Det) |
| Reactivity: | Human |
| Source: | Sf 9 (baculovirus) |
| Accession #: | P17936 |
| Applications: | Bioactivity |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ICC/IF |
![Western Blot: IGFBP-3 Antibody [H00003486-D01P]](https://resources.rndsystems.com/images/products/IGFBP-3-Antibody-Western-Blot-H00003486-D01P-img0006.jpg "Western Blot: IGFBP-3 Antibody [H00003486-D01P]")
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #84728 |
| Applications: | IHC, WB, ELISA(Cap), ELISA(Det) |
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #84728 |
| Applications: | IHC, WB, ELISA(Cap), ELISA(Det) |