Proteome Profiler Human Angiogenesis Array Kit

Contains 4 membranes - each spotted in duplicate with 55 different angiogenesis antibodies
  (78 citations)
(2 Reviews)
Datasheet / CoA / SDS
Product Details
Citations (78)
Supplemental Products
Kit Summary

A membrane-based antibody array for the parallel determination of the relative levels of selected angiogenesis-related proteins. Validated for analyte detection in cell culture supernates, cell lysates, tissue lysates, serum, plasma and saliva.

Troubleshooting Guide

Key Benefits

  • Detects 55 human angiogenesis-related proteins simultaneously
  • Requires no specialized equipment
  • Compatible with LI-COR and chemiluminescence detection

Principle of the Assay

The Proteome Profiler Human Angiogenesis Array Kit is a membrane-based sandwich immunoassay. Samples are mixed with a cocktail of biotinylated detection antibodies (Step 1) and then incubated with the array membrane which is spotted in duplicate with capture antibodies to specific target proteins (Step 2). Captured proteins are visualized using chemiluminescent detection reagents (Step 3). The signal produced is proportional to the amount of bound analyte. Analytes include soluble growth and differentiation factors, extracellular matrix components, proteases, membrane-bound receptors, and intracellular signaling molecules.

Why Use an Antibody Array to Detect Angiogenesis-Related Proteins?

Determining the expression of multiple proteins in a single sample can be expensive, time consuming and can require specialized equipment. Performing multiple immunoprecipitations and Western blots requires time, labor, and reagents. The use of a multiplex antibody array to detect multiple proteins in a single sample can be cost-effective and also save time and sample.



Kit Contents
  • 4 Array Membranes
  • 4-Well Multi-dish
  • Array Buffers
  • Wash Buffer
  • Antibody Detection Cocktail
  • Streptavidin-HRP
  • Chemiluminescent Detection Reagents
  • Transparency Overlay Template
  • Detailed Protocol

For a complete list of the kit contents and necessary materials, please see the Materials Provided/Other Supplies Required sections of the product datasheet.

Stability and Storage

Store the unopened kit at 2 °C to 8 °C. Do not use past kit expiration date.

Simultaneously detect the relative levels of these angiogenesis-related proteins in a single sample.
Angiopoietin-1 HB-EGF Persephin
Angiopoietin-2 HGF CXCL4/PF4
Angiostatin/Plasminogen IGFBP-1 PlGF
Amphiregulin IGFBP-2 Prolactin
Artemin IGFBP-3 Serpin B5/Maspin
Tissue Factor/Factor III IL-1 beta Serpin E1/PAI-1
CXCL16 CXCL8/IL-8 Serpin F1/PEDF
DPPIV/CD26 LAP (TGF-beta 1) TIMP-1
EGF Leptin TIMP-4
EG-VEGF CCL2/MCP-1 Thrombospondin-1
Endoglin/CD105 CCL3/MIP-1 alpha Thrombospondin-2
Endostatin/Collagen XVIII MMP-8 uPA
Endothelin-1 MMP-9 Vasohibin
FGF acidic NRG1-beta 1 VEGF
FGF basic Pentraxin 3 VEGF-C


Assays for analytes represented in the Human Angiogenesis Antibody Array Kit

  Quantikine® ELISA Kits DuoSet® ELISA Development Systems Quantikine® HS (High Sensitivity) ELISA Kits QuantiGlo® Chemiluminescent ELISA Kits
Activin A DAC00B DY338    
ADAMTS-1   DY2197    
Angiogenin DAN00 DY265    
Angiopoietin-1 DANG10 DY923    
Angiopoietin-2 DANG20 DY623    
Amphiregulin   DY262    
Artemin   DY2589    
Tissue Factor/Factor III DCF300 DY2339    
CXCL16 DCX160 DY1164    
DPPIV/CD26   DY1180    
EGF DEG00 DY236    
EG-VEGF   DY1209    
Endoglin DNDG00 DY1097    
Endostatin/Collagen XVII DNST0 DY1098    
Endothelin-1 DET100     QET00B
FGF acidic DFA00B DY232    
FGF basic DFB50 DY233 HSFB00D  
FGF-4   DY235    
FGF-7/KGF DKG00 DY251    
GDNF   DY212    
HB-EGF   DY259    
HGF DHG00 DY294    
IGFBP-1   DY871    
IGFBP-2 DGB200 DY674    
IGFBP-3 DGB300 DY675    
IL-1 beta DLB50 DY201 HSLB00D QLB00B
CXCL8/IL-8 D8000C DY208 HS800 Q8000B
TGF-beta1 (LAP) DB100B DY240    
Leptin DLP00 DY398    
CCL2/MCP-1 DCP00 DY279    
CCL3/MIP-1 alpha DMA00 DY270    
MMP-8 DMP800 DY908    
MMP-9 DMP900 DY911    
NRG1-beta1   DY377    
Pentraxin 3 DPTX30 DY1826    
PDGF-AA DAA00B DY221    
PDGF-AB/PDGF-BB DHD00C, DBB00 DY222, DY220    
CXCL4/PF4   DY795    
PlGF DPG00 DY264    
Prolactin DPRL00 DY682    
Serpin B5/Maspin        
Serpin E1/PAI-1 DSE100 DY1786    
Serpin F1/PEDF        
TIMP-1 DTM100 DY970    
TIMP-4 DTM400 DY974    
Thrombospondin-1 DTSP10 DY3074    
Thrombospondin-2 DTSP20 DY1635    
uPA DUPA00 DY1310    
VEGF-C DVEC00 DY752B    


Data Examples
Profiling Angiogenesis-Related Proteins in Human Cancer Tissues
View Larger Image

Profiling Angiogenesis-Related Proteins in Human Cancer Tissues.. A) The Proteome Profiler Human Angiogenesis Antibody Array (Catalog # ARY007) was used to profile angiogenesis-related proteins in tissues from human prostate, ovarian, and breast cancers. B) Histogram profiles for select analytes were generated by quantifying the mean spot pixel densities from the array membrane using image software.

Product Datasheets

Certificate of Analysis Lookup

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Note: Certificate of Analysis not available for kit components.

Certificate of Analysis Lookup

Certificate of Analysis Request Form

To download a Certificate of Analysis, please enter the catalog and lot numbers in the search box below.

Note: Certificate of Analysis not available for kit components.

Preparation and Storage
  • Stability & Storage
    Store the unopened product at 2 - 8 °C. Do not use past expiration date.
Background: Angiogenesis Assay Kits
Angiogenesis is the tightly regulated process by which new blood vessels are formed from the existing vasculature. This process is physiologically important for development and wound healing, and is also a common driver in multiple diseases including rheumatoid arthritis, atherosclerosis, macular degeneration, and cancer. Angiogenesis occurs in response to a variety of molecular cues. Generally, the angiogenic process includes endothelial cell proliferation, chemotactic endothelial cell migration through the extracellular matrix barrier, and the formation of capillary tubes. Physiological and pathological angiogenesis utilize many of the same cellular processes and molecular signaling networks, however the structures that form during pathological angiogenesis are often functionally abnormal.
  • Alternate Names:
    Angiogenesis Assay Kits

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

78 Citations: Showing 1 - 10
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Sample Type
  1. Plocabulin, a novel tubulin-binding agent, inhibits angiogenesis by modulation of microtubule dynamics in endothelial cells
    Authors: CM Galmarini, M Martin, BP Bouchet, MJ Guillen-Na, M Martínez-D, JF Martinez-L, A Akhmanova, P Aviles
    BMC Cancer, 2018;18(1):164.  2018
  2. Employing mesenchymal stem cells to support tumor-targeted delivery of extracellular vesicle (EV)-encapsulated microRNA-379
    Authors: KP O'Brien, S Khan, KE Gilligan, H Zafar, P Lalor, C Glynn, C O'Flathart, H Ingoldsby, P Dockery, A De Bhulbh, JR Schweber, K St John, M Leahy, JM Murphy, WM Gallagher, T O'Brien, MJ Kerin, RM Dwyer
    Oncogene, 2018;0(0):.  2018
  3. Stimulation of Interferon-Stimulated Gene 20 by Thyroid Hormone Enhances Angiogenesis in Liver Cancer
    Authors: SL Lin, SM Wu, IH Chung, YH Lin, CY Chen, HC Chi, TK Lin, CT Yeh, KH Lin
    Neoplasia, 2018;20(1):57-68.  2018
  4. Cell Spheroids with Enhanced Aggressiveness to Mimic Human Liver Cancer In Vitro and In Vivo
    Authors: HR Jung, HM Kang, JW Ryu, DS Kim, KH Noh, ES Kim, HJ Lee, KS Chung, HS Cho, NS Kim, DS Im, JH Lim, CR Jung
    Sci Rep, 2017;7(1):10499.  2017
  5. CD44 expression in endothelial colony-forming cells regulates neurovascular trophic effect
    Authors: S Sakimoto, V Marchetti, E Aguilar, K Lee, Y Usui, S Murinello, F Bucher, JK Trombley, R Fallon, R Wagey, C Peters, EL Scheppke, PD Westenskow, M Friedlande
    JCI Insight, 2017;2(2):e89906.  2017
  6. 15-Lipoxygenase-1 re-expression in colorectal cancer alters endothelial cell features through enhanced expression of TSP-1 and ICAM-1
    Authors: S Tunçer, AG Ke?kü?, M Çolako?lu, I Çimen, C Yener, Ö Konu, S Banerjee
    Cell. Signal., 2017;39(0):44-54.  2017
  7. Adipose progenitor cell secretion of GM-CSF and MMP9 promotes a stromal and immunological microenvironment that supports breast cancer progression
    Authors: F Reggiani, V Labanca, P Mancuso, C Rabascio, G Talarico, S Orecchioni, A Manconi, F Bertolini
    Cancer Res., 2017;0(0):.  2017
  8. Human adipose-derived mesenchymal stem cell-secreted CXCL1 and CXCL8 facilitate breast tumor growth by promoting angiogenesis
    Authors: Y Wang, J Liu, Q Jiang, J Deng, F Xu, X Chen, F Cheng, Y Zhang, Y Yao, Z Xia, X Xu, X Su, M Huang, L Dai, Y Yang, S Zhang, D Yu, RC Zhao, Y Wei, H Deng
    Stem Cells, 2017;0(0):.  2017
  9. Autophagy gene ATG7 regulates ultraviolet radiation-induced inflammation and skin tumorigenesis
    Authors: L Qiang, A Sample, CR Shea, K Soltani, KF Macleod, YY He
    Autophagy, 2017;0(0):0.  2017
  10. Antitumor activity of miR-34a in peritoneal mesothelioma relies on c-MET and AXL inhibition: persistent activation of ERK and AKT signaling as a possible cytoprotective mechanism
    Authors: R El Bezawy, M De Cesare, M Pennati, M Deraco, P Gandellini, V Zuco, N Zaffaroni
    J Hematol Oncol, 2017;10(1):19.  2017
  11. Combination curcumin and (-)-epigallocatechin-3-gallate inhibits colorectal carcinoma microenvironment-induced angiogenesis by JAK/STAT3/IL-8 pathway
    Authors: G Jin, Y Yang, K Liu, J Zhao, X Chen, H Liu, R Bai, X Li, Y Jiang, X Zhang, J Lu, Z Dong
    Oncogenesis, 2017;6(10):e384.  2017
  12. Metabolically conditioned media derived from bone marrow stromal cells or human skin fibroblasts act as effective chemoattractants for mesenchymal stem cells
    Authors: A Gabrielyan, E Neumann, M Gelinsky, A Rösen-Wolf
    Stem Cell Res Ther, 2017;8(1):212.  2017
  13. Neuroprotective Effects of Human Mesenchymal Stem Cells and Platelet-Derived Growth Factor on Human Retinal Ganglion Cells
    Authors: A Osborne, J Sanderson, KR Martin
    Stem Cells, 2017;0(0):.  2017
  14. Methyltransferase G9a promotes cervical cancer angiogenesis and decreases patient survival
    Authors: RJ Chen, CT Shun, ML Yen, CH Chou, MC Lin
    Oncotarget, 2017;8(37):62081-62098.  2017
  15. SCO-spondin oligopeptide inhibits angiogenesis in glioblastoma
    Authors: R Bibes, S Gobron, F Vincent, C Mélin, N Vedrenne, A Perraud, F Labrousse, MO Jauberteau, F Lalloué
    Oncotarget, 2017;8(49):85969-85983.  2017
  16. Targeted nanocomplex carrying siRNA against MALAT1 sensitizes glioblastoma to temozolomide
    Authors: SS Kim, JB Harford, M Moghe, A Rait, KF Pirollo, EH Chang
    Nucleic Acids Res., 2017;0(0):.  2017
  17. Sonic hedgehog (SHH) signaling improves the angiogenic potential of Wharton's jelly-derived mesenchymal stem cells�(WJ-MSC)
    Authors: G Zavala, CP Prieto, AA Villanueva, V Palma
    Stem Cell Res Ther, 2017;8(1):203.  2017
  18. Co-Culture of Tumor Spheroids and Fibroblasts in a Collagen Matrix-Incorporated Microfluidic Chip Mimics Reciprocal Activation in Solid Tumor Microenvironment
    PLoS ONE, 2016;11(7):e0159013.  2016
  19. Lysyl Oxidase (LOX) transcriptionally regulates SNAI2 expression and TIMP4 secretion in human cancers
    Authors: M Boufraqech, L Zhang, N Nilubol, SM Sadowski, S Kotian, MM Quezado, E Kebebew
    Clin Cancer Res, 2016;0(0):.  2016
  20. IGF1R as a Key Target in High Risk, Metastatic Medulloblastoma
    Authors: Matthew N Svalina
    Sci Rep, 2016;6(0):27012.  2016
  21. The Development of an Angiogenic Protein Signature in Ovarian Cancer Ascites as a Tool for Biologic and Prognostic Profiling
    Authors: Sofia-Paraskevi Trachana
    PLoS ONE, 2016;11(6):e0156403.  2016
  22. Prostacyclin-producing human mesenchymal cells target H19 lncRNA to augment endogenous progenitor function in hindlimb ischaemia
    Authors: Y Deng, Z Yang, T Terry, S Pan, DG Woodside, J Wang, K Ruan, JT Willerson, RA Dixon, Q Liu
    Nat Commun, 2016;7(0):11276.  2016
  23. A Long-Gap Peripheral Nerve Injury Therapy Using Human Skeletal Muscle-Derived Stem Cells (Sk-SCs): An Achievement of Significant Morphological, Numerical and Functional Recovery
    PLoS ONE, 2016;11(11):e0166639.  2016
  24. Ethanol extract of Lophatheri Herba exhibits anti-cancer activity in human cancer cells by suppression of metastatic and angiogenic potential
    Sci Rep, 2016;6(0):36277.  2016
  25. Hypoxia-induced responses by endothelial colony-forming cells are modulated by placental growth factor
    Stem Cell Res Ther, 2016;7(1):173.  2016
  26. The Angiogenic Secretome in VEGF overexpressing Breast Cancer Xenografts
    Sci Rep, 2016;6(0):39460.  2016
  27. Sphingosine 1 Phosphate at the Blood Brain Barrier: Can the Modulation of S1P Receptor 1 Influence the Response of Endothelial Cells and Astrocytes to Inflammatory Stimuli?
    Authors: Spampinato S, Obermeier B, Cotleur A, Love A, Takeshita Y, Sano Y, Kanda T, Ransohoff R
    PLoS ONE, 2015;10(7):e0133392.  2015
  28. CoREST1 promotes tumor formation and tumor stroma interactions in a mouse model of breast cancer.
    Authors: Mazumdar, Sohini, Arendt, Lisa M, Phillips, Sarah, Sedic, Maja, Kuperwasser, Charlott, Gill, Grace
    PLoS ONE, 2015;10(3):e0121281.  2015
  29. Signaling via PI3K/FOXO1A pathway modulates formation and survival of human embryonic stem cell-derived endothelial cells.
    Authors: Merkely B, Gara E, Lendvai Z, Skopal J, Leja T, Zhou W, Kosztin A, Varady G, Mioulane M, Bagyura Z, Nemeth T, Harding S, Foldes G
    Stem Cells Dev, 2015;24(7):869-78.  2015
  30. Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts.
    Authors: Paggetti J, Haderk F, Seiffert M, Janji B, Distler U, Ammerlaan W, Kim Y, Adam J, Lichter P, Solary E, Berchem G, Moussay E
    Blood, 2015;126(9):1106-17.  2015
  31. Inhibition of IGF-1-Mediated Cellular Migration and Invasion by Migracin A in Ovarian Clear Cell Carcinoma Cells.
    Authors: Ukaji T, Lin Y, Banno K, Okada S, Umezawa K
    PLoS ONE, 2015;10(9):e0137663.  2015
  32. Identification of Novel Biomarkers for Metastatic Colorectal Cancer Using Angiogenesis-Antibody Array and Intracellular Signaling Array.
    Authors: Chung S, Dwabe S, Elshimali Y, Sukhija H, Aroh C, Vadgama J
    PLoS ONE, 2015;10(8):e0134948.  2015
  33. Intratumoral CD14+ Cells and Circulating CD14+HLA-DRlo/neg Monocytes Correlate with Decreased Survival in Patients with Clear Cell Renal Cell Carcinoma.
    Authors: Gustafson M, Lin Y, Bleeker J, Warad D, Tollefson M, Crispen P, Bulur P, Harrington S, Laborde R, Gastineau D, Leibovich B, Cheville J, Kwon E, Dietz A
    Clin Cancer Res, 2015;21(18):4224-33.  2015
  34. RECK controls breast cancer metastasis by modulating a convergent, STAT3-dependent neoangiogenic switch.
    Authors: Walsh, L A, Roy, D M, Reyngold, M, Giri, D, Snyder, A, Turcan, S, Badwe, C R, Lyman, J, Bromberg, J, King, T A, Chan, T A
    Oncogene, 2015;34(17):2189-203.  2015
  35. Sourcing of an alternative pericyte-like cell type from peripheral blood in clinically relevant numbers for therapeutic angiogenic applications.
    Authors: Blocki A, Wang Y, Koch M, Goralczyk A, Beyer S, Agarwal N, Lee M, Moonshi S, Dewavrin J, Peh P, Schwarz H, Bhakoo K, Raghunath M
    Mol Ther, 2015;23(3):510-22.  2015
  36. Deficiency of endothelium-specific transcription factor Sox17 induces intracranial aneurysm.
    Authors: Lee S, Kim I, Ahn J, Woo D, Kim S, Song S, Koh G, Kim H, Jeon B, Kim I
    , 2015;0(0):.  2015
  37. Breast cancer cells condition lymphatic endothelial cells within pre-metastatic niches to promote metastasis.
    Authors: Lee E, Fertig E, Jin K, Sukumar S, Pandey N, Popel A
    Nat Commun, 2014;5(0):4715.  2014
  38. Histone deacetylase-3 mediates positive feedback relationship between anaphylaxis and tumor metastasis.
    Authors: Eom S, Kim Y, Park D, Lee H, Lee Y, Choe J, Kim Y, Jeoung D
    J Biol Chem, 2014;289(17):12126-44.  2014
  39. Angiogenesis stimulated by human kallikrein-related peptidase 12 acting via a platelet-derived growth factor B-dependent paracrine pathway.
    Authors: Kryza T, Achard C, Parent C, Marchand-Adam S, Guillon-Munos A, Iochmann S, Korkmaz B, Respaud R, Courty Y, Heuze-Vourc'h N
    FASEB J, 2014;28(2):740-51.  2014
  40. Lysophosphatidic acid enhanced the angiogenic capability of human chondrocytes by regulating Gi/NF-kB-dependent angiogenic factor expression.
    Authors: Chuang, Yi-Wen, Chang, Wen-Ming, Chen, Kai-Hua, Hong, Chang-Ze, Chang, Pey-Jium, Hsu, Hung-Chi
    PLoS ONE, 2014;9(5):e95180.  2014
  41. Treatment of medulloblastoma with oncolytic measles viruses expressing the angiogenesis inhibitors endostatin and angiostatin.
    Authors: Hutzen, Brian, Bid, Hemant K, Houghton, Peter J, Pierson, Christop, Powell, Kimerly, Bratasz, Anna, Raffel, Corey, Studebaker, Adam W
    BMC Cancer, 2014;14(0):206.  2014
  42. Lymphatic endothelial cells support tumor growth in breast cancer.
    Authors: Lee, Esak, Pandey, Niranjan, Popel, Aleksand
    Sci Rep, 2014;4(0):5853.  2014
  43. Ionizing radiation induces tumor cell lysyl oxidase secretion.
    Authors: Shen C, Sharma A, Vuong D, Erler J, Pruschy M, Broggini-Tenzer A
    BMC Cancer, 2014;14(0):532.  2014
  44. Surgical sutures filled with adipose-derived stem cells promote wound healing.
    Authors: Reckhenrich A, Kirsch B, Wahl E, Schenck T, Rezaeian F, Harder Y, Foehr P, Machens H, Egana J
    PLoS ONE, 2014;9(3):e91169.  2014
  45. Extract of Cordyceps militaris inhibits angiogenesis and suppresses tumor growth of human malignant melanoma cells.
    Authors: Ruma I, Putranto E, Kondo E, Watanabe R, Saito K, Inoue Y, Yamamoto K, Nakata S, Kaihata M, Murata H, Sakaguchi M
    Int J Oncol, 2014;45(1):209-18.  2014
  46. Mesenchymal stromal cells: inhibiting PDGF receptors or depleting fibronectin induces mesodermal progenitors with endothelial potential.
    Authors: Ball S, Worthington J, Canfield A, Merry C, Kielty C
    Stem Cells, 2014;32(3):694-705.  2014
  47. Aberrant chloride intracellular channel 4 expression contributes to endothelial dysfunction in pulmonary arterial hypertension.
    Authors: Wojciak-Stothard B, Abdul-Salam V, Lao K, Tsang H, Irwin D, Lisk C, Loomis Z, Stenmark K, Edwards J, Yuspa S, Howard L, Edwards R, Rhodes C, Gibbs J, Wharton J, Zhao L, Wilkins M
    Circulation, 2014;129(17):1770-80.  2014
  48. Peripheral Blood-Derived Mesenchymal Stromal Cells Promote Angiogenesis via Paracrine Stimulation of Vascular Endothelial Growth Factor Secretion in the Equine Model.
    Authors: Bussche L, Van de Walle G
    Stem Cells Transl Med, 2014;3(12):1514-25.  2014
  49. Staphylococcal nuclease domain containing-1 (SND1) promotes migration and invasion via angiotensin II type 1 receptor (AT1R) and TGFbeta signaling.
    Authors: Santhekadur P, Akiel M, Emdad L, Gredler R, Srivastava J, Rajasekaran D, Robertson C, Mukhopadhyay N, Fisher P, Sarkar D
    FEBS Open Bio, 2014;4(0):353-61.  2014
  50. Sortilin mediates the release and transfer of exosomes in concert with two tyrosine kinase receptors.
    Authors: Wilson C, Naves T, Vincent F, Melloni B, Bonnaud F, Lalloue F, Jauberteau M
    J Cell Sci, 2014;127(0):3983-97.  2014
  51. PTEN expression is involved in the invasive properties of HNSCC: a key protein to consider in locoregional recurrence.
    Authors: Mriouah J, Boura C, Gargouri M, Plenat F, Faivre B
    Int J Oncol, 2014;44(3):709-16.  2014
  52. A metabolic shift favoring sphingosine 1-phosphate at the expense of ceramide controls glioblastoma angiogenesis.
    Authors: Abuhusain, Hazem J, Matin, Azadeh, Qiao, Qiao, Shen, Han, Kain, Nupur, Day, Bryan W, Stringer, Brett W, Daniels, Benjamin, Laaksonen, Maarit A, Teo, Charlie, McDonald, Kerrie L, Don, Anthony
    J Biol Chem, 2013;288(52):37355-64.  2013
  53. A novel serum protein signature associated with resistance to epidermal growth factor receptor tyrosine kinase inhibitors in head and neck squamous cell carcinoma.
    Authors: Box C, Mendiola M, Gowan S, Box G, Valenti M, Brandon A, Al-Lazikani B, Rogers S, Wilkins A, Harrington K, Eccles S
    Eur J Cancer, 2013;49(0):2512-21.  2013
  54. Fibroblasts derived from human pluripotent stem cells activate angiogenic responses in vitro and in vivo.
    Authors: Shamis Y, Silva E, Hewitt K, Brudno Y, Levenberg S, Mooney D, Garlick J
    PLoS ONE, 2013;8(12):e83755.  2013
  55. Inhibition of TGF-β signaling by the fungal lactones (S)-curvularin, dehydrocurvularin, oxacyclododecindione and galiellalactone.
    Cytokine, 2013;61(1):285-96.  2013
  56. Ultraviolet B preconditioning enhances the hair growth-promoting effects of adipose-derived stem cells via generation of reactive oxygen species.
    Stem Cells Dev, 2013;22(1):158-68.  2013
  57. Functional and molecular characterization of ex vivo cultured epiretinal membrane cells from human proliferative diabetic retinopathy.
    Authors: Vereb Z, Lumi X, Andjelic S, Globocnik-Petrovic M, Urbancic M, Hawlina M, Facsko A, Petrovski G
    Biomed Res Int, 2013;2013(0):492376.  2013
  58. Differentiation state determines neural effects on microvascular endothelial cells.
    Authors: Muffley L, Pan S, Smith A, Ga M, Hocking A, Gibran N
    Exp Cell Res, 2012;318(16):2085-93.  2012
  59. Multifunction protein staphylococcal nuclease domain containing 1 (SND1) promotes tumor angiogenesis in human hepatocellular carcinoma through novel pathway that involves nuclear factor κB and miR-221.
    Authors: Santhekadur PK, Das SK, Gredler R, Chen D, Srivastava J, Robertson C, Baldwin AS, Fisher PB, Sarkar D
    J. Biol. Chem., 2012;287(17):13952-8.  2012
  60. Cyclin-dependent kinase 8 mediates chemotherapy-induced tumor-promoting paracrine activities.
    Authors: Porter, Donald C, Farmaki, Elena, Altilia, Serena, Schools, Gary P, West, Deborah, Chen, Mengqian, Chang, Bey-Dih, Puzyrev, Anatoliy, Lim, Chang-uk, Rokow-Kittell, Rebecca, Friedhoff, Lawrence, Papavassiliou, Athanasi, Kalurupalle, Swathi, Hurteau, Gregory, Shi, Jun, Baran, Phil S, Gyorffy, Balazs, Wentland, Mark P, Broude, Eugenia, Kiaris, Hippokra, Roninson, Igor B
    Proc Natl Acad Sci U S A, 2012;109(34):13799-804.  2012
  61. Tumour-secreted miR-9 promotes endothelial cell migration and angiogenesis by activating the JAK-STAT pathway.
    EMBO J., 2012;31(17):3513-23.  2012
  62. Primary tumor hypoxia recruits CD11b+/Ly6Cmed/Ly6G+ immune suppressor cells and compromises NK cell cytotoxicity in the premetastatic niche.
    Authors: Sceneay J, Chow M, Chen A, Halse H, Wong C, Andrews D, Sloan E, Parker B, Bowtell D, Smyth M, Moller A
    Cancer Res, 2012;72(16):3906-11.  2012
  63. Tumor-initiating cells of various tumor types exhibit differential angiogenic properties and react differently to antiangiogenic drugs.
    Authors: Benayoun L, Gingis-Velitski S, Voloshin T, Segal E, Segev R, Munster M, Bril R, Satchi-Fainaro R, Scherer S, Shaked Y
    Stem Cells, 2012;30(9):1831-41.  2012
  64. Late SV40 factor (LSF) enhances angiogenesis by transcriptionally up-regulating matrix metalloproteinase-9 (MMP-9).
    Authors: Santhekadur PK, Gredler R, Chen D
    J. Biol. Chem., 2012;287(5):3425-32.  2012
  65. Age-related changes in expression and function of Toll-like receptors in human skin.
    Authors: Iram N, Mildner M, Prior M, Petzelbauer P, Fiala C, Hacker S, Schoppl A, Tschachler E, Elbe-Burger A
    Development, 2012;139(22):4210-9.  2012
  66. Bone morphogenetic protein modulator BMPER is highly expressed in malignant tumors and controls invasive cell behavior.
    Authors: Heinke J, Kerber M, Rahner S
    Oncogene, 2012;31(24):2919-30.  2012
  67. The secretion pattern of perivascular fat cells is different from that of subcutaneous and visceral fat cells.
    Authors: Rittig K, Dolderer JH, Balletshofer B, Machann J, Schick F, Meile T, Kuper M, Stock UA, Staiger H, Machicao F, Schaller HE, Konigsrainer A, Haring HU, Siegel-Axel DI
    Diabetologia, 2012;55(5):1514-25.  2012
  68. Highly invasive melanoma cells activate the vascular endothelium via an MMP-2/integrin alphavbeta5-induced secretion of VEGF-A.
    Am. J. Pathol., 2012;181(2):693-705.  2012
  69. Met Receptor Tyrosine Kinase Signaling Induces Secretion of the Angiogenic Chemokine Interleukin-8/CXCL8 in Pancreatic Cancer.
    Authors: Hill KS, Gaziova I, Harrigal L
    PLoS ONE, 2012;7(7):e40420.  2012
  70. Mesenchymal stem cells from adipose and bone marrow promote angiogenesis via distinct cytokine and protease expression mechanisms.
    Authors: Kachgal S, Putnam AJ
    Angiogenesis, 2011;14(1):47-59.  2011
  71. Human amniotic fluid-derived mesenchymal stem cells as therapeutic vehicles: a novel approach for the treatment of bladder cancer.
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    Cancer Res., 2009;69(0):9354-9.  2009
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Other Experimental Details Human Angiogenesis Antibody Array was used to evaluate mesenchymal stem cells secretion profiles when seeded in various extracellular matrices. Great tool that ganarates lots of data!

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