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15 results for "P2Y Receptor Antagonists Small Molecules and Peptides" in Products

P2Y Receptor Antagonists Small Molecules and Peptides

P2Y Purinergic Receptor Family

The P2Y purinergic receptor family consists of 8 mammalian receptors (P2Y1, P2Y2, P2Y4, P2Y6, P2Y11, P2Y12, P2Y13 and P2Y14), as well as the non-mammalian chick p2y3, Xenopus p2y8 and turkey p2y receptors. The p2y9 and p2y10 receptors are orphan receptors, and p2y5 was found to be a leukotriene B4 receptor. The mammalian P2Y receptors bind adenine and/or uridine nucleotides, with each receptor having a unique binding profile.

P2Y receptors are GPCRs that have 7 ...

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Selective P2Y12 antagonist

Alternate Names: Plavix
Chemical Name: (S)-(+)-Methyl 2-(4,5,6,7-tetrahydrothieno[3,2-c]pyridin-5-yl)-2-(2-chlorophenyl)acetate hydrogen sulfate
Purity: ≥98%
Selective P2Y12 antagonist
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Selective P2Y1 antagonist

Chemical Name: 2'-Deoxy-N6-methyladenosine 3',5'-bisphosphate tetrasodium salt
Purity: ≥98%
Selective P2Y1 antagonist
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Highly potent and selective P2Y1 antagonist

Chemical Name: (1R*,2S*)-4-[2-Iodo-6-(methylamino)-9H-purin-9-yl]-2-(phosphonooxy)bicyclo[3.1.0]hexane-1-methanol dihydrogen phosphate ester tetraammonium salt
Purity: ≥96%
Highly potent and selective P2Y1 antagonist
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Highly potent P2Y12 antagonist

Chemical Name: 1-Amino-9,10-dihydro-9,10-dioxo-4-[[4-(phenylamino)-3-sulfophenyl]amino]-2-anthracenesulfonic acid sodium salt
Purity: ≥95%
Highly potent P2Y12 antagonist
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Non-selective P2 antagonist

Chemical Name: 8,8'-[Carbonylbis[imino-3,1-phenylenecarbonylimino(4-methyl-3,1-phenylene)carbonylimino]]bis-1,3,5-naphthalenetrisulfonic acid hexasodium salt
Purity: ≥98%
Non-selective P2 antagonist
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High affinity and selective P2Y14 antagonist

Chemical Name: 4-[4-(4-Piperidinyl)phenyl]-7-[4-(trifluoromethyl)phenyl]-2-naphthalenecarboxylic acid hydrochloride
Purity: ≥98%
High affinity and selective P2Y14 antagonist
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Selective P2Y6 antagonist

Chemical Name: N,N''-1,4-Butanediylbis[N'-(3-isothiocyanatophenyl)thiourea
Purity: ≥95%
Selective P2Y6 antagonist
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Selective P2Y11 and P2X1 antagonist

Chemical Name: 8,8'-[Carbonylbis[imino-3,1-phenylenecarbonylimino(4-fluoro-3,1-phenylene)carbonylimino]]bis-1,3,5-naphthalenetrisulfonic acid hexasodium salt
Purity: ≥90%
Selective P2Y11 and P2X1 antagonist
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Selective and competitive P2Y2 antagonist

Chemical Name: 5-[[5-(2,8-Dimethyl-5H-dibenzo[a,d]cyclohepten-5-yl)-3,4-dihydro-2-oxo-4-thioxo-1(2H)-pyrimidinyl]methyl]-N-2H-tetrazol-5-yl-2-furancarboxamide
Purity: ≥97%
Selective and competitive P2Y2 antagonist
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Non-selective P2 antagonist

Chemical Name: Pyridoxalphosphate-6-azophenyl-2',4'-disulfonic acid tetrasodium salt
Non-selective P2 antagonist
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Selective P2Y12 antagonist

Alternate Names: Plavix
Chemical Name: Methyl 2-(4,5,6,7-tetrahydrothieno[3,2-c]pyridin-5-yl)-2-(2-chlorophenyl)acetate hydrochloride
Purity: ≥98%
Selective P2Y12 antagonist
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Competitive P2Y13 antagonist

Chemical Name: 2-[(2-Chloro-5-nitrophenyl)azo]-5-hydroxy-6-methyl-3-[(phosphonooxy)methyl]-4-pyridinecarboxaldehyde disodium salt
Purity: ≥96%
Competitive P2Y13 antagonist
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Highly potent P2Y12 antagonist

Alternate Names: Cangrelor tetrasodium salt
Chemical Name: N-[2-(Methylthio)ethyl]-2-[(3,3,3-trifluoropropyl)thio]adenosine-5'-O-(β,γ-dichloromethylene)triphosphate tetrasodium salt
Purity: ≥98%
Highly potent P2Y12 antagonist
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P2Y1 allosteric antagonist

Chemical Name: N-[2-[2-(1,1-Dimethylethyl)phenoxy]-3-pyridinyl]-N'-[4-(trifluoromethoxy)phenyl]urea
Purity: ≥98%
P2Y1 allosteric antagonist
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High affinity P2Y12 antagonist

Chemical Name: Ethyl 5-cyano-2-methyl-6-[4-[[[(phenylmethyl)sulfonyl]amino]carbonyl]-1-piperidinyl]-3-pyridinecarboxylate
Purity: ≥98%
High affinity P2Y12 antagonist
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