TGF-beta RI/ALK-5: Products

Most cell types express three sizes of receptors for TGF-beta. These are designated Type I (53 kDa), Type II (70 - 85 kDa), and Type III (250 - 350 kDa). The Type I receptor is a membrane-bound serine/threonine kinase that apparently requires the presence of the Type II receptor to bind TGF-beta.

"TGF-beta RI/ALK-5" has 33 results in Products.
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SB 431542 

SB 431542 synthesized to cGMP guidelines

A 83-01 

Selective inhibitor of TGF-βRI, ALK4 and ALK7

SB 431542 

Potent, selective inhibitor of TGF-βRI, ALK4 and ALK7

Recombinant Human TGF-beta RI/ALK-5 Fc Avi-tag Protein, CF 

Biotinylated
2 Images
Bioactivity

RepSox 

Potent and selective inhibitor of TGF-βRI

Recombinant Mouse TGF-beta RI/ALK-5 Fc Chimera Protein, CF 

This item is in process of being discontinued.
1 Image
Bioactivity

SB 525334 

Selective inhibitor of TGF-βRI

SB 505124 

Selective inhibitor of TGF-βRI, ALK4 and ALK7

Galunisertib 

ALK4 and ALK5 (TGFβRI) inhibitor

Human/Mouse TGF-beta  RI/ALK-5 Antibody 

Recombinant Monoclonal Antibody.

LY 364947 

Selective inhibitor of TGF-βRI

D 4476 

Selective CK1 inhibitor. Also inhibits TGF-βRI

GW 788388 

Potent and selective inhibitor of TGF-βRI

SD 208 

Potent ATP-competitive TGF-βRI inhibitor

R 268712 

Potent and selective inhibitor of TGF-βRI

IN 1130 

Potent and selective inhibitor of TGF-βRI

SM 16 

Potent TGF-βRI inhibitor; orally bioavailable

A 77-01 

Potent inhibitor of TGF-βRI

AZ 12799734 

Potent TGF-βRI inhibitor

A 83-01 

A 83-01 synthesized to Ancillary Material Grade

RepSox 

RepSox synthesized to Ancillary Material Grade

Human TGF-beta  RI/ALK-5 Antibody 

Recombinant Monoclonal Antibody.
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