214 results for "TGF-beta RI/ALK-5" in Products
TGF-beta RI/ALK-5 Products
Most cell types express three sizes of receptors for TGF-beta. These are designated Type I (53 kDa), Type II (70 - 85 kDa), and Type III (250 - 350 kDa). The Type I receptor is a membrane-bound serine/threonine kinase that apparently requires the presence of the Type II receptor to bind TGF-beta. The Type II receptor is also a membrane-bound serine/threonine kinase that binds TGF-beta1 and TGF-beta 3 with high affinity and TGF-beta 2 with much lower affinity. The Type I and Type II receptors ...
Potent, selective inhibitor of TGF-βRI, ALK4 and ALK7
| Chemical Name: | 4-[4-(1,3-benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]benzamide |
| Purity: | ≥99% |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ELISA, ICC/IF |
| Reactivity: | Human, Mouse |
| Details: | Rat IgG2A Monoclonal Clone #141231 |
| Applications: | WB |
| Reactivity: | Mouse |
| Source: | Sf 21 (baculovirus) |
| Accession #: | BAA05023.1 |
| Applications: | Bioactivity |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Source: | NS0 |
| Accession #: | P36897 |
| Applications: | Bioactivity |
| Reactivity: | Mouse |
| Details: | Rat IgG2A Monoclonal Clone #141229 |
| Applications: | WB |
Recombinant Monoclonal Antibody.
| Reactivity: | Human, Mouse |
| Details: | Rat IgG2A Monoclonal Clone #141231R |
| Applications: | WB |
Recombinant Monoclonal Antibody.
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #854621R |
| Applications: | ELISA |
| Reactivity: | Mouse |
| Applications: |
| Reactivity: | Human |
| Applications: |
| Reactivity: | Mouse |
| Details: | Rat IgG2 Monoclonal Clone #RM0016-3A11 |
| Applications: | IHC, WB |
![Immunohistochemistry-Paraffin: TGF-beta RI/ALK-5 Antibody (RM0016-3A11) - Azide and BSA Free [NBP2-11921]](https://resources.rndsystems.com/images/products/TGF-beta-RI-ALK-5-Antibody-RM0016-3A11-Immunohistochemistry-Paraffin-NBP2-11921-img0002.jpg "Immunohistochemistry-Paraffin: TGF-beta RI/ALK-5 Antibody (RM0016-3A11) - Azide and BSA Free [NBP2-11921]")
| Reactivity: | Human |
| Applications: | WB |
![Western Blot: TGF-beta RI/ALK-5 Overexpression Lysate [NBL1-16856]](https://resources.rndsystems.com/images/products/TGF-beta-Receptor-I-Overexpression-Lysate-Adult-Normal-Western-Blot-NBL1-16856-img0002.jpg "Western Blot: TGF-beta RI/ALK-5 Overexpression Lysate [NBL1-16856]")
| Reactivity: | Human |
| Source: | Baculovirus |
| Applications: | PAGE |
![SDS-PAGE: Recombinant Human TGF-beta RI/ALK-5 Isoform 1 hIgG-His Protein [NBP2-61985]](https://resources.rndsystems.com/images/products/Recombinant-Human-TGF-beta-RI-ALK-5-Isoform-1-Protein-SDS-Page-NBP2-61985-img0001.jpg "SDS-PAGE: Recombinant Human TGF-beta RI/ALK-5 Isoform 1 hIgG-His Protein [NBP2-61985]")
| Reactivity: | Human |
| Sensitivity: | 0.118 ng/mL (example only; lot dependent) |
| Assay Range: | 0.312 - 20 ng/mL (example only; lot dependent) |
| Applications: | ELISA |
| Reactivity: | Human |
| Sensitivity: | 0.118 ng/mL (example only; lot dependent) |
| Assay Range: | 0.312 - 20 ng/mL (example only; lot dependent) |
| Applications: | ELISA |
SB 431542 synthesized to cGMP guidelines
| Chemical Name: | 4-[4-(1,3-benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]benzamide |
| Purity: | ≥99% |
Potent and selective inhibitor of TGF-βRI
| Alternate Names: | E-616452,SJN 2511,ALK5 Inhibitor II |
| Chemical Name: | 2-(3-(6-Methylpyridine-2-yl)-1H-pyrazol-4-yl)-1,5-naphthyridine |
| Purity: | ≥99% |
RepSox synthesized to Ancillary Material Grade
| Alternate Names: | ALK5 Inhibitor II,SJN 2511,E-616452 |
| Chemical Name: | 2-[3-(6-Methylpyridin-2-yl)-1H-pyrazol-4-yl]-1,5-naphthyridine |
| Purity: | ≥99% |
ALK4 and ALK5 (TGFβRI) inhibitor
| Alternate Names: | LY 2157299 |
| Chemical Name: | 4-[5,6-Dihydro-2-(6-methyl-2-pyridinyl)-4H-pyrrolo[1,2-b]pyrazol-3-yl]-6-quinolinecarboxamide |
| Purity: | ≥98% |
Biotinylated
| Reactivity: | Human |
| Source: | HEK293 |
| Accession #: | P36897.1 |
| Applications: | Bioactivity |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human, Mouse |
| Details: | Rat IgG2A Monoclonal Clone #141231 |
| Applications: | WB |
Recombinant Monoclonal Antibody.
| Reactivity: | Human, Mouse |
| Details: | Rat IgG2A Monoclonal Clone #141231R |
| Applications: | WB |