Fetal Bovine Serum

Fetal Bovine Serum (FBS) is the ideal cell growth supplement and generally preferred over other types of cell culture sera. The significantly lower content of antibodies compared to adult and newborn sera minimizes the risk of antibody cross reaction with cells in culture. It’s high level of nutrients and optimal combination of growth factors makes Fetal Bovine Serum the most effective cell growth promoter for virtually any cell culture system.

Standard Grades of FBS Specialty Grades of FBS FBS Quality
Which FBS is Best for Your Cells?

Standard Grades for Fetal Bovine Serum

Keeping your cell culture requirements in mind, we offer several grades of fetal bovine serum to support a broad spectrum of culture needs. All standard grades of fetal bovine serum are also available heat inactivated.

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Grade of Fetal Bovine Serum Material Origin Additional Features Heat Inactivated Available?
Premium Grade Fetal Bovine Serum USDA-approved FBS The most affordable grade of fetal bovine serum Yes
Optima Grade Fetal Bovine Serum US Origin FBS, USDA-Aphis certified Additional extensive biochemical profile and extended virus testing to provide piece of mind for our serum users. It also includes a comprehensive quality assurance testing. Yes
Premium Select Grade Fetal Bovine Serum USDA-approved FBS The highest quality FBS grade. Additional extensive hormone profiling, biochemical analysis, and rigorous viral testing for specific research applications requiring this data. Yes

Specialty Grades of Fetal Bovine Serum

In addition to our standard grades of fetal bovine serum, R&D Systems also offers specialty grades of fetal bovine serum. These sera have been selected for specialty cell culture applications such as embryonic stem cell cultures, hybridoma technology, TET systems and cell lines, and more. All our specialty grades of fetal bovine serum as also available heat inactivated.

Specialty Fetal Bovine Serum Material Origin Additional Features Heat Inactivated Available?
Embryonic Stem Cell Qualified Fetal Bovine Serum USDA-approved FBS Removes the need for time-consuming pre-screening of multiple lots of serum. This specialty fetal bovine serum ensures stability when culturing embryonic stem cells by screening for plating efficiency, colony morphology, and cytotoxicity, while also maintaining cells in their undifferentiated state. Yes
Hybridoma Qualified Fetal Bovine Serum USDA-approved FBS Designed for the culture of hybridoma and myeloma cells. This specialty FBS has been screened to show superior growth at limiting dilutions and lack of cytotoxicity in growth studies. Yes
TET Tested Fetal Bovine Serum USDA-approved FBS Designed for used in TET Systems and cell lines. This specialty grade of FBS shows undetectable levels of tetracycline and tetracycline-derivatives, measured throughout serum production. Yes
Charcoal/Dextran Treated Fetal Bovine Serum US Origin FBS, USDA-approved FBS Designed for use in cultures requiring lower levels of hormones, steroids, or growth factors in serum, such as the fields of insulin and estrogen research. This specialty FBS is screened for various hormones and steroids before and after treatment. Yes
Dialyzed Fetal Bovine Serum US Origin FBS Designed for use in cell culture systems requiring reduced concentrations od low molecular weight components, such as nucleotides, amino acids, hormones, salts, and small proteins. This serum is dialyzed against physiological saline using a 12 – 14 kiloDalton (kDa) cutoff membrane using a controlled process where glucose concentration is precisely monitored throughout the procedure. Exhaustive dialysis is not performed in order to prevent precipitation and inactivation of serum peptides. Yes

FBS Quality

R&D Systems offers a wide variety of fetal bovine serum, manufactured at our ISO 9001:2105 certified facility, to support general cell culture, stem cell cultures, and many other specialized cell culture needs. We have USDA APHIS-certified, US Origin, and USDA-approved grades of FBS. We recognize the vital impact of quality fetal bovine serum for today’s evolving cell culture technology and is proud to have an established a network of raw materials to ensure direct control over all processes involved in the manufacture of our fetal bovine serum.