Our CellXVivo™ Immune Cell Differentiation and Expansion Kits include optimized cytokine combinations and protocols for the differentiation and expansion of dendritic cells, T helper cell subtypes, regulatory T cells, and B cells.
Differentiates CD14+ monocytes into monocyte-derived dendritic cells.
Differentiates mouse bone marrow cells into dendritic cells.
Differentiates CD14+ monocytes into M1 macrophage cells.
Differentiates CD14+ monocytes into M2 macrophage cells.
Differentiates naïve CD4+ lymphocytes into mature Th1 effector cells.
Differentiates naïve CD4+ lymphocytes into mature Th2 effector cells.
Differentiates naïve CD4+ human lymphocytes into CD25+FoxP3+ regulatory T cells.
Differentiates naïve CD4+ mouse lymphocytes into CD25+FoxP3+ regulatory T cells.
Expands human CD3+CD56+ cytokine-induced killer (CIK) cell populations from PBMCs.
Expands B cell populations.
A 500X cocktail of Monensin, PMA, and Ionomycin for activating immune cells.
Leukocyte maturation into immune effector cell types occurs in vivo following immune insults or injuries, making it challenging to harvest populations of mature human immune cells without significant variability. In an effort to simplify and reduce variability during the procurement of mature leukocyte populations, R&D Systems offers CellXVivo™ kits to expand and differentiate mature lymphoid and myeloid immune cell types from enriched populations of peripheral blood mononuclear cells (PBMCs). These kits contain the high-quality reagents and optimized protocols needed to drive efficient differentiation or expansion. CellXVivo™ Immune Cell Differentiation and Expansion Kits are developed and optimized to be used in conjunction with our MagCellect™ Cell Selection Kits.