Human CRHBP Antibody
Human CRHBP Antibody Summary
Accession # P24387.2
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Human CRHBP is a 37 kDa secreted glycoprotein that likely serves to regulate CRH availability to the adrenal. In human, CRHBP complexes with CRH to form a circulating 41 kDa complex. In rodent and horse, this complex is restricted to the CNS. Human CRHBP is synthesized as a 322 amino acid (aa) precursor that contains a 24 aa signal sequence and a 298 aa mature region. The mature region contains one potential CUB domain and five intrachain disulfide bonds. Human mature CRHBP shares 87% and 84% sequence identity with mouse and equine CRHBP, respectively.
Citations for Human CRHBP Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
Citations: Showing 1 - 2
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Decreased CRHBP expression is predictive of poor prognosis in patients with hepatocellular carcinoma
Authors: HB Xia, HJ Wang, LQ Fu, SB Wang, L Li, GQ Ru, XL He, XM Tong, XZ Mou, DS Huang
Oncol Lett, 2018;16(3):3681-3689.
Sample Types: Whole Tissue
Reduced mrna expression level of corticotropin-releasing hormone-binding protein is associated with aggressive human kidney cancer.
Authors: Tezval H, Atschekzei F, Peters I, Waalkes S, Hennenlotter J, Stenzl A, Becker J, Merseburger A, Kuczyk M, Serth J
BMC Cancer, 2013;13(0):199.
Sample Types: Tissue Homogenates
Applications: Western Blot
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