Human CRHBP Antibody

Catalog # Availability Size / Price Qty
Product Details
Citations (2)
Supplemental Products
Reviews (4)

Human CRHBP Antibody Summary

Species Reactivity
Detects human CRHBP in direct ELISAs and Western blots. In direct ELISAs, approximately 30% cross-reactivity with recombinant mouse CRHBP is observed.
Polyclonal Goat IgG
Antigen Affinity-purified
Mouse myeloma cell line NS0-derived recombinant human CRHBP
Accession # P24387.2
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.


Recommended Concentration
Western Blot
0.1 µg/mL
Recombinant Human CRHBP
5-15 µg/mL
Immersion fixed paraffin-embedded sections of human liver

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.


Preparation and Storage

Reconstitute at 0.2 mg/mL in sterile PBS.
Reconstitution Buffer Available
Reconstitution Buffer 1 (PBS)
Catalog #
Size / Price
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: CRHBP

Human CRHBP is a 37 kDa secreted glycoprotein that likely serves to regulate CRH availability to the adrenal. In human, CRHBP complexes with CRH to form a circulating 41 kDa complex. In rodent and horse, this complex is restricted to the CNS. Human CRHBP is synthesized as a 322 amino acid (aa) precursor that contains a 24 aa signal sequence and a 298 aa mature region. The mature region contains one potential CUB domain and five intrachain disulfide bonds. Human mature CRHBP shares 87% and 84% sequence identity with mouse and equine CRHBP, respectively.

Long Name
Corticotropin Releasing Hormone Binding Protein
Entrez Gene IDs
1393 (Human)
Alternate Names
corticotropin releasing hormone binding protein; corticotropin-releasing factor-binding protein; Corticotropin-releasing hormone-binding protein; CRFBP; CRFBPcorticotropin releasing hormone-binding protein; CRF-BPCRF-binding protein; CRHBP; CRH-BP

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Citations for Human CRHBP Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

2 Citations: Showing 1 - 2
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  1. Decreased CRHBP expression is predictive of poor prognosis in patients with hepatocellular carcinoma
    Authors: HB Xia, HJ Wang, LQ Fu, SB Wang, L Li, GQ Ru, XL He, XM Tong, XZ Mou, DS Huang
    Oncol Lett, 2018;16(3):3681-3689.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC-P
  2. Reduced mrna expression level of corticotropin-releasing hormone-binding protein is associated with aggressive human kidney cancer.
    Authors: Tezval H, Atschekzei F, Peters I, Waalkes S, Hennenlotter J, Stenzl A, Becker J, Merseburger A, Kuczyk M, Serth J
    BMC Cancer, 2013;13(0):199.
    Species: Human
    Sample Types: Tissue Homogenates
    Applications: Western Blot


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Isotype Controls

Reconstitution Buffers

Secondary Antibodies

Goat IgG (H+L) Antibody


Reviews for Human CRHBP Antibody

Average Rating: 3.8 (Based on 4 Reviews)

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Human CRHBP Antibody
By Jon Ladd on 06/10/2020
Application: Microarrays Sample Tested: EDTA Plasma Species: Human

Human CRHBP Antibody
By Anonymous on 11/10/2018
Application: ELISA Sample Tested: Plasma Species: Human

Human CRHBP Antibody
By Anonymous on 11/07/2018
Application: Microarrays Sample Tested: EDTA Plasma Species: Human

Human CRHBP Antibody
By Anonymous on 11/02/2018
Application: MiAr Sample Tested: EDTA Plasma Species: Human