Human mGluR3 Antibody

Catalog # Availability Size / Price Qty
Detection of MGLUR3 in HEK293 Human Cell Line Transfected with Human MGLUR3 and eGFP by Flow Cytometry.
2 Images
Product Details
Supplemental Products

Human mGluR3 Antibody Summary

Species Reactivity
Detects human mGluR3 in direct ELISAs.
Monoclonal Mouse IgG2B Clone # 530503
Protein A or G purified from hybridoma culture supernatant
Chinese hamster ovary cell line CHO-derived recombinant human mGluR3
Accession # Q14832
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.


Recommended Concentration
Flow Cytometry
0.25 µg/106 cells
See below
5-25 µg/mL
Immersion fixed paraffin-embedded sections of human hypothalamus tissue
Ready to be labeled using established conjugation methods. No BSA or other carrier proteins that could interfere with conjugation.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Flow Cytometry Detection of MGLUR3 antibody in HEK293 Human Cell Line Transfected with Human MGLUR3 and eGFP antibody by Flow Cytometry. View Larger

Detection of MGLUR3 in HEK293 Human Cell Line Transfected with Human MGLUR3 and eGFP by Flow Cytometry. HEK293 human embryonic kidney cell line transfected with human MGLUR3 and eGFP was stained with (A) Mouse Anti-Human MGLUR3 Monoclonal Antibody (Catalog # MAB4668) or (B) Mouse IgG2B isotype control antibody (Catalog # MAB0041) followed by APC-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # F0101B). View our protocol for Staining Membrane-associated Proteins.

Immunohistochemistry mGluR3 antibody in Human Hypothalamus Tissue by Immunohistochemistry (IHC-P). View Larger

mGluR3 in Human Hypothalamus Tissue. mGluR3 was detected in immersion fixed paraffin-embedded sections of human hypothalamus tissue using Mouse Anti-Human mGluR3 Monoclonal Antibody (Catalog # MAB4668) at 5 µg/mL for 1 hour at room temperature followed by incubation with the Anti-Mouse IgG VisUCyte™ HRP Polymer Antibody (VC001). Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic (CTS013). Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to cell membrane in neurons. Staining was performed using our IHC Staining with VisUCyte HRP Polymer Detection Reagents protocol.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.


Preparation and Storage

Reconstitute at 0.5 mg/mL in sterile PBS.
Reconstitution Buffer Available
Reconstitution Buffer 1 (PBS)
Catalog #
Size / Price
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: mGluR3

Metabotropic glutamate receptor 3 (mGluR3) is a 90-100 kDa, 7-transmembrane glycoprotein that belongs to group II of the C-family of G-protein coupled receptors. It is a presynaptic receptor expressed on both neurons and glia, whose activation reduces adenylate cyclase activity. Mature human mGluR3 is 857 amino acids in length and contains a 554 amino acid (aa) N-terminal extracellular domain (ECD) (aa 23-576). The ECD binds glutamate and forms homodimers. There is one alternative splice form that is soluble, 515 aa in length and shows a 96 aa substitution for aa 442-879. Over aa 25-507, human mGluR3 shares 97% aa sequence identity with mouse and rat mGluR3 and 67% aa sequence identity with hGluR2.

Long Name
Metabotropic Glutamate Receptor 3
Entrez Gene IDs
2913 (Human); 108069 (Mouse); 24416 (Rat)
Alternate Names
GLUR3; glutamate receptor, metabotropic 3; GPRC1C; GPRC1Cglutamate metabotropic receptor 3; GRM3; mGlu3; mGluR3; MGLUR3metabotropic glutamate receptor 3

Product Datasheets

You must select a language.



No product specific FAQs exist for this product, however you may

View all Antibody FAQs

Isotype Controls

Reconstitution Buffers

Secondary Antibodies

Reviews for Human mGluR3 Antibody

There are currently no reviews for this product. Be the first to review Human mGluR3 Antibody and earn rewards!

Have you used Human mGluR3 Antibody?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review