Human/Mouse Glypican 5 Antibody Summary
Glu25-Thr554
Accession # P78333
Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Reconstitution Calculator
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: Glypican 5
Glypican 5 (GPC5) belongs to the Glypican family of heparan sulfate proteoglycans that are linked to the cell surface through a glycosyl-phosphatidylinositol anchor. Glypican 5 is expressed primarily in embryonic neurons and mesenchyme.
Product Datasheets
Citations for Human/Mouse Glypican 5 Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Citations: Showing 1 - 7
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Development of a novel anti-human glypican 5 monoclonal antibody (G5Mab-1) for multiple applications
Authors: Kaneko, Y;Tanaka, T;Fujisawa, S;Li, G;Satofuka, H;Kaneko, MK;Suzuki, H;Kato, Y;
Biochemistry and biophysics reports
Species: Chinese Hamster, Human
Sample Types: Whole Cells
Applications: Immunocytochemistry -
?-Amyloid induces microglial expression of GPC4 and APOE leading to increased neuronal tau pathology and toxicity.
Authors: Holmes, BB;Weigel, TK;Chung, JM;Kaufman, SK;Apresa, BI;Byrnes, JR;Kumru, KS;Vaquer-Alicea, J;Gupta, A;Rose, IVL;Zhang, Y;Nana, AL;Alter, D;Grinberg, LT;Spina, S;Leung, KK;Miller, BL;Condello, C;Kampmann, M;Seeley, WW;Coutinho-Budd, JC;Wells, JA;
Molecular neurodegeneration
Species: Human
Sample Types: Whole Cells
Applications: Immunocytochemistry -
?-Amyloid Induces Microglial Expression of GPC4 and APOE Leading to Increased Neuronal Tau Pathology and Toxicity
Authors: Holmes, BB;Weigel, TK;Chung, JM;Kaufman, SK;Apresa, BI;Byrnes, JR;Kumru, KS;Vaquer-Alicea, J;Gupta, A;Rose, IVL;Zhang, Y;Nana, AL;Alter, D;Grinberg, LT;Spina, S;Leung, KK;Condello, C;Kampmann, M;Seeley, WW;Coutinho-Budd, JC;Wells, JA;
bioRxiv : the preprint server for biology
Species: Human
Sample Types: Whole Cells
Applications: Immunocytochemistry -
Subcellular localization of glypican-5 is associated with dynamic motility of the human mesenchymal stem cell line U3DT
Authors: M Takeuchi, K Takeuchi, T Takai, R Yamaguchi, T Furukawa, KI Akagi, JK Takeuchi
PLoS ONE, 2021-02-19;16(2):e0226538.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Heparan sulfate proteoglycans containing a glypican 5 core and 2-O-sulfo-iduronic acid function as Sonic Hedgehog co-receptors to promote proliferation.
Authors: Witt, Rochelle, Hecht, Marie-Ly, Pazyra-Murphy, Maria F, Cohen, Samuel M, Noti, Christia, van Kuppevelt, Toin H, Fuller, Maria, Chan, Jennifer, Hopwood, John J, Seeberger, Peter H, Segal, Rosalind
J Biol Chem, 2013-07-18;288(36):26275-88.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
Role for amplification and expression of glypican-5 in rhabdomyosarcoma.
Authors: Williamson D, Selfe J, Lu YJ, Pritchard-Jones K, Murai K, Jones P, Workman P, Shipley J
Cancer Res., 2007-01-01;67(1):57-65.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot -
Glypican-5 stimulates rhabdomyosarcoma cell proliferation by activating Hedgehog signaling
Authors: Fuchuan Li, Wen Shi, Mariana Capurro, Jorge Filmus
Journal of Cell Biology
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