Human NAIP Antibody

Catalog # Availability Size / Price Qty
Detection of Human NAIP by Western Blot.
2 Images
Product Details
Supplemental Products

Human NAIP Antibody Summary

Species Reactivity
Detects human NAIP in Western blots. In direct ELISAs, no cross-reactivity with recombinant mouse (rm) NAIP or rmNAIP2 is observed.
Monoclonal Mouse IgG1 Clone # 541609
Protein A or G purified from hybridoma culture supernatant
E.coli-derived recombinant human NAIP
Accession # Q13075
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.


Recommended Concentration
Western Blot
1 µg/mL
See below
8-25 µg/mL
See below

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Data Examples

Western Blot Detection of Human NAIP antibody by Western Blot. View Larger

Detection of Human NAIP by Western Blot. Western blot shows lysates of HEK293 human embryonic kidney cell line either mock transfected or transfected with human NAIP and human brain (cerebellum) tissue. PVDF Membrane was probed with 1 µg/mL of Human NAIP Monoclonal Antibody (Catalog # MAB829) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF007). A specific band was detected for NAIP at approximately 160 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 2.

Immunohistochemistry NAIP antibody in Human Brain by Immunohistochemistry (IHC-P). View Larger

NAIP in Human Brain. NAIP was detected in immersion fixed paraffin-embedded sections of human brain (cerebellum) using Human NAIP Monoclonal Antibody (Catalog # MAB829) at 15 µg/mL overnight at 4 °C. Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic (Catalog # CTS013). Tissue was stained using the Anti-Mouse HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS002) and counterstained with hematoxylin (blue). Specific staining was localized to Purkinje neurons. View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.


Preparation and Storage

Sterile PBS to a final concentration of 0.5 mg/mL.
Reconstitution Buffer Available
Reconstitution Buffer 1 (PBS)
Catalog #
Size / Price
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: NAIP

Neuronal apoptosis inhibitory protein (NAIP; also Baculoviral IAP repeat-containing protein 1) is a 160 kDa member of the inhibitor of apoptosis family of proteins (also known as BIRC proteins). Human NAIP is 1403 amino acids (aa) in length.  It contains three distinct regions: an N-terminal cluster of three baculoviral inhibitory repeat (BIR) domains, a central nucleotide binding oligomerization domain (NOD), and a C-terminal leucine-rich repeat (LRR) domain.  Human NAIP shares 68% aa identity with mouse NAIP.  NAIP is expressed in motor neurons, but not in sensory neurons.  It is also expressed in the liver, placenta and to a lesser extent in the spinal cord.  NAIP prevents motor neuron apoptosis, and defects in NAIP have been found in individuals with spinal muscular atrophy.

Long Name
Neuronal Apoptosis Inhibitor Protein
Entrez Gene IDs
4671 (Human); 17940 (Mouse); 191568 (Rat)
Alternate Names
baculoviral IAP repeat-containing 1; BIRC1; BIRC1baculoviral IAP repeat-containing protein 1; FLJ18088; FLJ42520; FLJ58811; NAIP; Neuronal apoptosis inhibitory protein; NLR family, apoptosis inhibitory protein; NLR family, BIR domain containing 1; NLRB1; nucleotide-binding oligomerization domain, leucine rich repeat and BIR domaincontaining 1; psi neuronal apoptosis inhibitory protein; psiNAIP

Product Datasheets


No product specific FAQs exist for this product, however you may

View all Antibody FAQs

Cell and Tissue Staining Kits

Immunohistochemistry Reagents

Isotype Controls

Reconstitution Buffers

Secondary Antibodies

Reviews for Human NAIP Antibody

There are currently no reviews for this product. Be the first to review Human NAIP Antibody and earn rewards!

Have you used Human NAIP Antibody?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review