Human Phospho-Src (Y419) Antibody Summary
Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Data Examples

Src in Human Colon.

Detection of Human Phospho-Src (Y419) by Western Blot.

Src in Human Liver Cancer Tissue.

Src in Human Liver.

Detection of Human Phospho-Src (Y419) by Simple WesternTM.
Reconstitution Calculator
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: Src
Src and other Src family protein tyrosine kinases are proto-oncogenes that play key roles in regulating cell growth and differentiation. Src family activity is regulated by tyrosine phosphorylation at two sites with opposing effects. Phosphorylation at Y419 of human Src up-regulates kinase activity, while phosphorylation at Y530 inactivates Src.
Product Datasheets
Citations for Human Phospho-Src (Y419) Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Citations: Showing 1 - 5
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Role and regulation of Yap in KrasG12D-induced lung cancer
Authors: Y Mao, S Sun, KD Irvine
Oncotarget, 2017;8(67):110877-110889.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC-Fr -
Clonorchis sinensis excretory-secretory products promote the migration and invasion of cholangiocarcinoma cells by activating the integrin ?4-FAK/Src signaling pathway
Authors: JH Pak, Q Bashir, IK Kim, SJ Hong, S Maeng, YY Bahk, TS Kim
Mol. Biochem. Parasitol, 2017;0(0):.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot -
Intravitreal AAV2.COMP-Ang1 Prevents Neurovascular Degeneration in a Murine Model of Diabetic Retinopathy.
Authors: Cahoon J, Rai R, Carroll L, Uehara H, Zhang X, O'Neil C, Medina R, Das S, Muddana S, Olson P, Nielson S, Walker K, Flood M, Messenger W, Archer B, Barabas P, Krizaj D, Gibson C, Li D, Koh G, Gao G, Stitt A, Ambati B
Diabetes, 2015;64(12):4247-59.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot -
Kaposi's sarcoma-associated herpesvirus induces rapid release of angiopoietin-2 from endothelial cells.
Authors: Ye F, Zhou F, Nithianantham S, Chandran B, Yu X, Weinberg A, Gao S
J Virol, 2013;87(11):6326-35.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot -
Targeting Src in Mucinous Ovarian Carcinoma.
Authors: Matsuo K, Nishimura M, Bottsford-Miller JN, Huang J, Komurov K, Armaiz-Pena GN, Shahzad MM, Stone RL, Roh JW, Sanguino AM, Lu C, Im DD, Rosenshien NB, Sakakibara A, Nagano T, Yamasaki M, Enomoto T, Kimura T, Ram PT, Schmeler KM, Gallick GE, Wong KK, Frumovitz M, Sood AK
Clin. Cancer Res., 2011;17(16):5367-5378.
Species: Human
Sample Types: Whole Tissue
Applications: IHC-P
FAQs
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