Human RAR beta /NR1B2 Antibody

R&D Systems | Catalog # PP-H4338-00

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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Western Blot, Direct ELISA, Immunoprecipitation

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2A Clone # H4338
View all RAR beta/NR1B2 Primary Antibodies »

Product Specifications

Immunogen

Recombinant human RAR beta/NR1B2
aa 2-79

Specificity

This antibody specifically recognizes human RAR beta and does not cross-react with human RAR alpha or RAR gamma. Not yet tested in other species.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Applications for Human RAR beta /NR1B2 Antibody

Application
Recommended Usage

Direct ELISA

This antibody can be used at 0.2 μg/mL with the appropriate secondary reagents to detect human RAR beta.

Immunoprecipitation

Optimal dilutions should be determined by each laboratory.

Western Blot

This antibody can be used at 1 μg/mL under reducing conditions with the appropriate secondary reagents to detect human RAR beta.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

A liquid formulation in physiologic saline with 0.1% NaN3.

Shipping

The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

This antibody is stable for greater than six months when held at -20 °C in a manual defrost freezer or at -70 °C. Upon thawing, the antibody can be stored at 2-8 °C for at least 1 month without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Background: RAR beta/NR1B2

Retinoic Acid Receptor beta (RAR beta, hap; NR1B2) is closely related to the Thyroid hormone Receptor (TR). RARs bind to two retinoids, all-trans retinoic acid and 9-cis retinoic acid. RAR beta is expressed in the ovary, uterus, mammary cell lines, and adult and fetal spleen. RARs have been associated with several diseases, among which cancer is one of the most important. RAR beta takes part in apoptosis.

Long Name

Retinoic Acid Receptor, beta

Alternate Names

HAP, NR1B2, RARB, RRB2

Entrez Gene IDs

5915 (Human)

Gene Symbol

RARB

Additional RAR beta/NR1B2 Products

Product Documents for Human RAR beta /NR1B2 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Human RAR beta /NR1B2 Antibody

For research use only

Citations for Human RAR beta /NR1B2 Antibody

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FAQs

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