Human RAR beta /NR1B2 Antibody

  (1 citations)     
Datasheet / CoA / SDS
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Citations (1)
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  • Species Reactivity
    Human
  • Specificity
    This antibody specifically recognizes human RAR beta and does not cross-react with human RAR alpha or RAR gamma. Not yet tested in other species.
  • Source
    Monoclonal Mouse IgG2A Clone # H4338
  • Purification
    Protein A or G purified from hybridoma culture supernatant
  • Immunogen
    Recombinant human RAR beta/NR1B2
    aa 2-79
  • Formulation
    A liquid formulation in physiologic saline with 0.1% NaN3.
  • Label
    Unconjugated
Product Datasheets

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Applications
  •  
    Recommended
    Concentration
    Sample
  • Western Blot
    This antibody can be used at 1 μg/mL under reducingconditions with the appropriate secondary reagents to detect human RAR beta.
  • Immunoprecipitation
    Optimal dilutions should be determined by eachlaboratory.
  • Direct ELISA
    This antibody can be used at 0.2 μg/mL with the appropriatesecondary reagents to detect human RAR beta.
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Preparation and Storage
  • Shipping
    The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.
  • Stability & Storage
    This antibody is stable for greater than six months when held at -20 °C in a manual defrost freezer or at -70 °C. Upon thawing, the antibody can be stored at 2-8 °C for at least 1 month without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Background: RAR beta/NR1B2
Retinoic Acid Receptor beta (RAR beta, hap; NR1B2) is closely related to the Thyroid hormone Receptor (TR). RARs bind to two retinoids, all-trans retinoic acid and 9-cis retinoic acid. RAR beta is expressed in the ovary, uterus, mammary cell lines, and adult and fetal spleen. RARs have been associated with several diseases, among which cancer is one of the most important. RAR beta takes part in apoptosis.
  • Long Name:
    Retinoic Acid Receptor, beta
  • Entrez Gene IDs:
    5915 (Human)
  • Alternate Names:
    beta polypeptide; HAP; HBV-activated protein; NR1B2; RAR beta; RARB; retinoic acid receptor, beta; RRB2
Related Research Areas
Citations:

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

1 Citations: Showing 1 - 1

  1. RAR?/RXR Synergism Potentiates Retinoid Responsiveness in Cutaneous T Cell Lymphoma Cell Lines
    Authors: L Wang, SS DeMarco, MS Peaks, AL Maiorana-B, J Chen, MJ Crouch, BM Shewchuk, SR Shaikh, CM Phillips, LC Bridges
    Exp. Dermatol., 2017;0(0):.
    Species: Human
    Sample Type: Cell Lysates
    Application: WB

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