Human SOX17 Antibody Summary
Asp177-Val414
Accession # Q9H6I2
Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Data Examples

Detection of Human SOX17 by Western Blot. Western blot shows lysates of BG01V human embryonic stem cells untreated (-) or endoderm differentiated (+). PVDF membrane was probed with 1 µg/mL of Goat Anti-Human SOX17 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1924) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF109). A specific band was detected for SOX17 at approximately 55 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

Detection of SOX17-regulated Genes by Chromatin Immunoprecipitation. Endoderm-differentiated D3 mouse embryonic stem cell line was fixed using formaldehyde, resuspended in lysis buffer, and sonicated to shear chromatin. SOX17/DNA complexes were immunoprecipitated using 5 µg Goat Anti-Human SOX17 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1924) or control antibody (Catalog # AB-108-C) for 15 minutes in an ultrasonic bath, followed by Biotinylated Anti-Goat IgG Secondary Antibody (Catalog # BAF109). Immunocomplexes were captured using 50 µL of MagCellect Streptavidin Ferrofluid (Catalog # MAG999) and DNA was purified using chelating resin solution. Thep21promoter was detected by standard PCR.

SOX17 in B16 Mouse Cell Line. SOX17 was detected in immersion fixed B16 mouse melanoma cell line using 10 µg/mL Goat Anti-Human SOX17 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1924) for 3 hours at room temperature. Cells were stained with the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red; Catalog # NL001) and counter-stained with DAPI (blue). View our protocol for Fluorescent ICC Staining of Cells on Coverslips.

SOX17 in Human BG01V Cells. SOX17 was detected in immersion fixed endoderm differentiated BG01V human embryonic stem cells using 10 µg/mL Goat Anti-Human SOX17 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1924) for 3 hours at room temperature. Cells were stained with the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red, upper panel; Catalog # NL001) and counterstained with DAPI (blue, lower panel). View our protocol for Fluorescent ICC Staining of Cells on Coverslips.

Detection of Human SOX17 by Simple WesternTM. Simple Western lane view shows lysates of BG01V human embryonic stem cells untreated (-) or endoderm differentiated (+), loaded at 0.2 mg/mL. A specific band was detected for SOX17 at approximately 59 kDa (as indicated) using 10 µg/mL of Goat Anti-Human SOX17 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1924) followed by 1:50 dilution of HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF109). This experiment was conducted under reducing conditions and using the 12-230 kDa separation system.

Detection of Human SOX17 by Simple WesternTM. Simple Western lane view shows lysates of iBJ6 human induced pluripotent stem cell line untreated (-) or endoderm differentiated (+), loaded at 0.2 mg/mL. A specific band was detected for SOX17 at approximately 58 kDa (as indicated) using 10 µg/mL of Goat Anti-Human SOX17 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1924) followed by 1:50 dilution of HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF109). This experiment was conducted under reducing conditions and using the 12-230 kDa separation system.
Reconstitution Calculator
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: SOX17
SOX17 is a member of the SOX family of transcription factors that bind DNA via a high mobility group (HMG) domain. SOX17 is suggested to play an important role in endoderm development (1, 2).
- Kanai-Azuma, M. et al. (2002) Development 129:2367.
- Katoh, M. et al. (2002) Int. J. Mol. Med. 9:153.
Product Datasheets
Citations for Human SOX17 Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Citations: Showing 1 - 10
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Generation of one iPSC line (IMEDEAi007-A) by Sendai Virus transduction of PBMCs from a Psoriasis donor
Authors: S Vallejo-Di, A Fleischer, J María Mart, A Sánchez-Gi, C Gómez-Mart, M Castresana, D Bachiller
Stem Cell Res, 2020;47(0):101917.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of a human induced pluripotent stem cell line derived from a Parkinson's disease patient carrying SNCA duplication
Authors: H Suzuki, N Egawa, T Kondo, K Imamura, T Enami, K Tsukita, M Suga, R Shibukawa, Y Okanishi, T Uchiyama, H Inoue, R Takahashi
Stem Cell Res, 2020;45(0):101828.
Species: Human
Sample Types: Whole Cell
Applications: Flow Cytometry -
Comparative analysis of the mitochondrial morphology, energy metabolism, and gene expression signatures in three types of blastocyst-derived stem cells
Authors: J Choi, BJ Seo, H La, SH Yoon, YJ Hong, JH Lee, HM Chung, K Hong, JT Do
Redox Biol, 2020;30(0):101437.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Multipotent RAG1+ progenitors emerge directly from haemogenic endothelium in human pluripotent stem cell-derived haematopoietic organoids
Authors: A Motazedian, FF Bruveris, SV Kumar, JV Schiesser, T Chen, ES Ng, AP Chidgey, CA Wells, AG Elefanty, EG Stanley
Nat. Cell Biol., 2020;22(1):60-73.
Species: Mouse
Sample Types: PSCs
Applications: IF -
Generation of a human induced pluripotent stem cell line, BRCi005-A, derived from a Best disease patient with BEST1 mutations
Authors: K Kamata, Y Otsuka, K Imamura, A Oishi, T Kondo, M Suga, R Shibukawa, Y Okanishi, Y Sagara, K Tsukita, T Yasukawa, H Usui, K Muguruma, A Tsujikawa, H Inoue
Stem Cell Res, 2020;45(0):101782.
Species: Human
Sample Types: Whole Cell
Applications: ICC -
Generation of a human induced pluripotent stem cell line, BRCi004-A, derived from a patient with age-related macular degeneration
Authors: K Kamata, Y Otsuka, K Imamura, A Oishi, T Kondo, M Suga, R Shibukawa, Y Okanishi, Y Sagara, K Tsukita, T Yasukawa, H Usui, K Muguruma, A Tsujikawa, H Inoue
Stem Cell Res, 2020;45(0):101787.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of two hiPSC lines (MHHi016-A, MHHi016-B) from a primary ciliary dyskinesia patient carrying a homozygous 5�bp duplication (c.248_252dup (p.Gly85Cysfs*11)) in exon 1 of the CCNO gene
Authors: J Dahlmann, A Sahabian, N Drick, A Haase, G Göhring, N Lachmann, FC Ringshause, T Welte, U Martin, R Olmer
Stem Cell Res, 2020;46(0):101850.
Species: Human
Sample Types: Whole Cell
Applications: Flow Cytometry -
Generation of two human induced pluripotent stem cell lines (MHHi017-A, MHHi017-B) from a patient with primary ciliary dyskinesia carrying a homozygous mutation (c.7915C�>�T [p.Arg2639*]) in the DNAH5 gene
Authors: N Drick, J Dahlmann, A Sahabian, A Haase, G Göhring, N Lachmann, FC Ringshause, T Welte, U Martin, R Olmer
Stem Cell Res, 2020;46(0):101848.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of three induced pluripotent stem cell lines from a Parkinson's disease patient with mutant PARKIN�(p. C253Y)
Authors: M Tariq, H Liu, DP Ibañez, Y Li, S Chen, M Jiang, W Fan, P Zhao, Z Luo, D Wang, S Kanwal
Stem Cell Res, 2020;45(0):101822.
Species: Human
Sample Types: Whole Cells
Applications: Functional Assay -
Generation of human induced pluripotent stem cell line LUMCi027-A and its isogenic gene-corrected line from a patient affected by arrhythmogenic cardiomyopathy and carrying the c.2013delC PKP2 mutation
Authors: V Meraviglia, CH Arendzen, M Tok, C Freund, AS Maione, E Sommariva, M Bellin
Stem Cell Res, 2020;46(0):101835.
Species: Human
Sample Types: Whole Cell
Applications: ICC -
iPSC-Derived Intestinal Organoids from Cystic Fibrosis Patients Acquire CFTR Activity upon TALEN-Mediated Repair of the p.F508del Mutation
Authors: A Fleischer, S Vallejo-Dí, JM Martín-Fer, A Sánchez-Gi, M Castresana, A Del Pozo, A Esquisabel, S Ávila, JL Castrillo, E Gaínza, JL Pedraz, M Viñas, D Bachiller
Mol Ther Methods Clin Dev, 2020;17(0):858-870.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation and Profiling of 2,135 Human ESC Lines for the Systematic Analyses of Cell States Perturbed by Inducing Single Transcription Factors
Authors: Y Nakatake, SBH Ko, AA Sharov, S Wakabayash, M Murakami, M Sakota, N Chikazawa, C Ookura, S Sato, N Ito, M Ishikawa-H, SS Mak, LM Jakt, T Ueno, K Hiratsuka, M Matsushita, SK Goparaju, T Akiyama, KI Ishiguro, M Oda, N Gouda, A Umezawa, H Akutsu, K Nishimura, R Matoba, O Ohara, MSH Ko
Cell Rep, 2020;31(7):107655.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Intrauterine Pressures Adjusted by Reichert's Membrane Are Crucial for Early Mouse Morphogenesis
Authors: Y Ueda, C Kimura-Yos, K Mochida, M Tsume, Y Kameo, T Adachi, O Lefebvre, R Hiramatsu, I Matsuo
Cell Rep, 2020;31(7):107637.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
Generation of two human induced pluripotent stem cell lines, LUMCi020-A and LUMCi021-A, from two patients with Catecholaminergic Polymorphic Ventricular Tachycardia carrying heterozygous mutations in the RYR2 gene
Authors: V Meraviglia, CH Arendzen, C Freund, DE Atsma, CL Mummery, M Bellin
Stem Cell Res, 2020;45(0):101764.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of an induced pluripotent stem cell line (DANi-011A) from a Parkinson's disease patient with a LRRK2 p.G2019S mutation
Authors: M Chen, M Maimaitili, SH Buchholdt, UB Jensen, F Febbraro, M Denham
Stem Cell Res, 2020;45(0):101781.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of intestinal organoids derived from human pluripotent stem cells for drug testing
Authors: S Yoshida, H Miwa, T Kawachi, S Kume, K Takahashi
Sci Rep, 2020;10(1):5989.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Gallbladder wall abnormality in biliary atresia of mouse Sox17+/- neonates and human infants
Authors: M Uemura, M Higashi, M Pattarapan, S Takami, N Ichikawa, H Higashiyam, T Furukawa, J Fujishiro, Y Fukumura, T Yao, T Tajiri, M Kanai-Azum, Y Kanai
Dis Model Mech, 2020;13(4):.
Species: Human
Sample Types: Whole Tissue
Applications: IHC -
Generation and characterization of four Chediak-Higashi Syndrome (CHS) induced pluripotent stem cell (iPSC) lines
Authors: J Serra-Vina, MB Sandler, E Pak, W Zheng, A Dutra, W Introne, WA Gahl, MC Malicdan
Stem Cell Res, 2020;47(0):101883.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of one iPSC line (IMEDEAi006-A) from an early-onset familial Alzheimer's Disease (fAD) patient carrying the E280A mutation in the PSEN1 gene
Authors: S Vallejo-Di, A Fleischer, JM Martín-Fer, A Sánchez-Gi, M Castresana, D Aguillón, A Villegas, CA Mastronard, LG Espinosa, M Arcos-Burg, Á Del Pozo, E Herrán, E Gainza, M Isaza-Ruge, F Lopera, D Bachiller
Stem Cell Res, 2019;37(0):101440.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
In vitro metabolic zonation through oxygen gradient on a chip
Authors: F Tonon, GG Giobbe, A Zambon, C Luni, O Gagliano, A Floreani, G Grassi, N Elvassore
Sci Rep, 2019;9(1):13557.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
A versatile toolbox for knock-in gene targeting based on the Multisite Gateway technology
Authors: S Yoshimatsu, T Sone, M Nakajima, T Sato, R Okochi, M Ishikawa, M Nakamura, E Sasaki, S Shiozawa, H Okano
PLoS ONE, 2019;14(8):e0221164.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Regulatory pathways governing murine coronary vessel formation are dysregulated in the injured adult heart
Authors: S Payne, M Gunadasa-R, A Neal, AN Redpath, J Patel, KM Chouliaras, I Ratnayaka, N Smart, S De Val
Nat Commun, 2019;10(1):3276.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC-Fr -
SMYD2 Drives Mesendodermal Differentiation of Human Embryonic Stem Cells through Mediating the Transcriptional Activation of Key Mesendodermal Genes
Authors: HJ Bai, P Zhang, L Ma, H Liang, G Wei, HT Yang
Stem Cells, 2019;0(0):.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot -
Loss of Cubilin, the intrinsic factor-vitamin B12 receptor, impairs visceral endoderm endocytosis and endodermal patterning in the mouse
Authors: A Perea-Gome, O Cases, V Lelièvre, MV Pulina, J Collignon, AK Hadjantona, R Kozyraki
Sci Rep, 2019;9(1):10168.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
Generation of a heterozygous COL1A1 (c.3969_3970insT) osteogenesis imperfecta mutation human iPSC line, MCRIi001-A-1, using CRISPR/Cas9 editing
Authors: H Hosseini F, YN Patria, A Motazedian, AG Elefanty, EG Stanley, SR Lamandé, JF Bateman
Stem Cell Res, 2019;37(0):101449.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
The use of simultaneous reprogramming and gene correction to generate an osteogenesis imperfecta patient COL1A1 c. 3936 G>T iPSC line and an isogenic control iPSC line
Authors: S Howden, H Hosseini F, A Motazedian, AG Elefanty, EG Stanley, SR Lamandé, JF Bateman
Stem Cell Res, 2019;38(0):101453.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Chemically defined and xenogeneic-free differentiation of human pluripotent stem cells into definitive endoderm in 3D culture
Authors: U Diekmann, H Wolling, R Dettmer, I Niwolik, O Naujok, FFR Buettner
Sci Rep, 2019;9(1):996.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Novel hybrid three-dimensional artificial liver using human induced pluripotent stem cells and a rat decellularized liver scaffold
Authors: T Minami, T Ishii, K Yasuchika, K Fukumitsu, S Ogiso, Y Miyauchi, H Kojima, T Kawai, R Yamaoka, Y Oshima, H Kawamoto, M Kotaka, K Yasuda, K Osafune, S Uemoto
Regen Ther, 2019;10(0):127-133.
Species: Human
Sample Types: Liver hiPSCs
Applications: ICC -
Single-Cell RNA-Sequencing-Based CRISPRi Screening Resolves Molecular Drivers of Early Human Endoderm Development
Authors: RMJ Genga, EM Kernfeld, KM Parsi, TJ Parsons, MJ Ziller, R Maehr
Cell Rep, 2019;27(3):708-718.e10.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Characterization of the first induced pluripotent stem cell line generated from a patient with autosomal dominant catecholaminergic polymorphic ventricular tachycardia due to a heterozygous mutation in cardiac calsequestrin-2
Authors: S Ross, M Holliday, S Lim, C Semsarian
Stem Cell Res, 2019;37(0):101450.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
The BAF and PRC2 Complex Subunits Dpf2 and Eed Antagonistically Converge on Tbx3 to Control ESC Differentiation
Authors: W Zhang, C Chronis, X Chen, H Zhang, R Spalinskas, M Pardo, L Chen, G Wu, Z Zhu, Y Yu, L Yu, J Choudhary, J Nichols, MM Parast, B Greber, P Sahlén, K Plath
Cell Stem Cell, 2019;24(1):138-152.e8.
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot -
Histone H3K9 Methyltransferase G9a in Oocytes Is Essential for Preimplantation Development but Dispensable for CG Methylation Protection
Authors: WK Au Yeung, J Brind'Amou, Y Hatano, K Yamagata, R Feil, MC Lorincz, M Tachibana, Y Shinkai, H Sasaki
Cell Rep, 2019;27(1):282-293.e4.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
Generation of a human induced pluripotent stem cell line, BRCi001-A, derived from a patient with mucopolysaccharidosis type I
Authors: M Suga, T Kondo, K Imamura, R Shibukawa, Y Okanishi, Y Sagara, K Tsukita, T Enami, M Furujo, K Saijo, Y Nakamura, M Osawa, MK Saito, S Yamanaka, H Inoue
Stem Cell Res, 2019;36(0):101406.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of human antral and fundic gastric organoids from pluripotent stem cells
Authors: TR Broda, KW McCracken, JM Wells
Nat Protoc, 2019;14(1):28-50.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Human induced pluripotent stem cell-derived vocal fold mucosa mimics development and responses to smoke exposure
Authors: V Lungova, X Chen, Z Wang, C Kendziorsk, SL Thibeault
Nat Commun, 2019;10(1):4161.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Efficient generation of human primordial germ cell-like cells from pluripotent stem cells in a methylcellulose-based 3D system at large scale
Authors: X Wang, T Liao, C Wan, X Yang, J Zhao, R Fu, Z Yao, Y Huang, Y Shi, G Chang, Y Zheng, F Luo, Z Liu, Y Wang, X Mao, XY Zhao
PeerJ, 2019;6(0):e6143.
Species: Human
Sample Types: Whole Tissue
Applications: IHC-Fr -
Establishment and characterization of induced pluripotent stem cells (iPSCs) from central nervous system lupus erythematosus
Authors: MT De Angelis, G Santamaria, EI Parrotta, S Scalise, M Lo Conte, S Gasparini, E Ferlazzo, U Aguglia, C Ciampi, A Sgura, G Cuda
J. Cell. Mol. Med., 2019;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Single-cell qPCR demonstrates that Repsox treatment changes cell fate from endoderm to neuroectoderm and disrupts epithelial-mesenchymal transition
Authors: Q Li, Q Huang
PLoS ONE, 2019;14(10):e0223724.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Uterine SOX17: a key player in human endometrial receptivity and embryo implantation
Authors: S Kinnear, LA Salamonsen, M Francois, V Harley, J Evans
Sci Rep, 2019;9(1):15495.
Species: Human
Sample Types: Whole Tissue
Applications: IHC -
Generation of gene-corrected iPSC line, KIOMi002-A, from Parkinson's disease patient iPSC with LRRK2 G2019S mutation using BAC-based homologous recombination
Authors: SY Lee, SK Chung
Stem Cell Res, 2019;41(0):101649.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of Mouse Parthenogenetic Epiblast Stem Cells and Their Imprinting Patterns
Authors: BJ Seo, HS Jang, H Song, C Park, K Hong, JW Lee, JT Do
Int J Mol Sci, 2019;20(21):.
Species: Mouse
Sample Types: Whole Cells
Applications: ICC -
Dissecting the dynamics of signaling events in the BMP, WNT, and NODAL cascade during self-organized fate patterning in human gastruloids
Authors: S Chhabra, L Liu, R Goh, X Kong, A Warmflash
PLoS Biol., 2019;17(10):e3000498.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Induced pluripotent stem cell line (INSAi001-A) from a Gaucher disease type 3 patient compound heterozygote for mutations in the GBA1 gene
Authors: AJ Duarte, D Ribeiro, R Santos, L Moreira, J Bragança, O Amaral
Stem Cell Res, 2019;41(0):101595.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of an induced pluripotent stem cell line (GIBHi003-A) from a Parkinson's disease patient with mutant PINK1 (p. I368N)
Authors: MM Abdul, DP Ibañez, P Zhao, H Liu, X Zhong, Y Li, M Zhang, W Li, Y Li, C Ward, S Chen, D Wang, B Qin, MA Esteban, X Wang, W Fan, Z Luo
Stem Cell Res, 2019;41(0):101607.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of a homozygous HDAC6 knockout human embryonic stem cell line by CRISPR/Cas9 editing
Authors: L Xie, J Huang, X Li, L Dai, X Lin, J Zhang, J Luo, W Zhang
Stem Cell Res, 2019;41(0):101610.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of a knock-in MAP2-tdTomato reporter human embryonic stem cell line with inducible expression of NEUROG2/1 (NYGCe001-A)
Authors: C Lu, NE Sanjana
Stem Cell Res, 2019;41(0):101643.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Single cell census of human kidney organoids shows reproducibility and diminished off-target cells after transplantation
Authors: A Subramania, EH Sidhom, M Emani, K Vernon, N Sahakian, Y Zhou, M Kost-Alimo, M Slyper, J Waldman, D Dionne, LT Nguyen, A Weins, JL Marshall, O Rosenblatt, A Regev, A Greka
Nat Commun, 2019;10(1):5462.
Species: Mouse
Sample Types: Organoid
Applications: ICC -
Wnt Inhibition Facilitates RNA-Mediated Reprogramming of Human Somatic Cells to Naive Pluripotency
Authors: N Bredenkamp, J Yang, J Clarke, GG Stirparo, F von Meyenn, S Dietmann, D Baker, R Drummond, Y Ren, D Li, C Wu, M Rostovskay, S Eminli-Mei, A Smith, G Guo
Stem Cell Reports, 2019;13(6):1083-1098.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of an induced pluripotent stem cell line (UBCi001-A) from a presymptomatic individual carrying the R418X progranulin gene mutation
Authors: J Frew, X Wu, GY Hsiung, HH Feldman, IR Mackenzie, HB Nygaard
Stem Cell Res, 2019;41(0):101582.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of eight human induced pluripotent stem cell lines from Parkinson's disease patients carrying familial mutations
Authors: M Chen, M Maimaitili, SH Buchholdt, UB Jensen, F Febbraro, M Denham
Stem Cell Res, 2019;42(0):101657.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of a NKX2.1 - p63 double transgenic knock-in reporter cell line from human induced pluripotent stem cells (MHHi006-A-4)
Authors: N Drick, A Sahabian, P Pongpamorn, S Merkert, G Göhring, T Welte, U Martin, R Olmer
Stem Cell Res, 2019;42(0):101659.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Molecular determinants of nephron vascular specialization in the kidney
Authors: DM Barry, EA McMillan, B Kunar, R Lis, T Zhang, T Lu, E Daniel, M Yokoyama, JM Gomez-Sali, A Sureshbabu, O Cleaver, A Di Lorenzo, ME Choi, J Xiang, D Redmond, SY Rabbany, T Muthukumar, S Rafii
Nat Commun, 2019;10(1):5705.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
Circadian Entrainment Triggers Maturation of Human In�Vitro Islets
Authors: JR Alvarez-Do, J Donaghey, N Rasouli, JHR Kenty, A Helman, J Charlton, JR Straubhaar, A Meissner, DA Melton
Cell Stem Cell, 2019;26(1):108-122.e10.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of two induced pluripotent stem cells lines from Mucopolysaccharydosis IIIA patient: IMEDEAi004-A and IMEDEAi004-B
Authors: S Vallejo, A Fleischer, JM Martín, A Sánchez, E Palomino, D Bachiller
Stem Cell Res, 2018;32(0):110-114.
Species: Human
Sample Types:
-
Generation of nine induced pluripotent stem cell lines as an ethnic diversity panel
Authors: X Gao, JJ Yourick, RL Sprando
Stem Cell Res, 2018;31(0):193-196.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of a human Juvenile myelomonocytic leukemia iPSC line, CHOPi001-A, with a mutation in CBL
Authors: AL Gagne, JA Maguire, S Gandre-Bab, ST Chou, SK Tasian, ML Loh, MJ Weiss, P Gadue, DL French
Stem Cell Res, 2018;31(0):157-160.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of a homozygous CRISPR/Cas9-mediated knockout human iPSC line for the STUB1 locus
Authors: S Schuster, S Saravanaku, L Schöls, S Hauser
Stem Cell Res, 2018;34(0):101378.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of Spinocerebellar Ataxia Type 2 induced pluripotent stem cell lines, CHOPi002-A and CHOPi003-A, from patients with abnormal CAG repeats in the coding region of the ATXN2 gene
Authors: JA Maguire, AL Gagne, P Gonzalez-A, BL Davidson, V Shakkottai, P Gadue, DL French
Stem Cell Res, 2018;34(0):101361.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
yylncT Defines a Class of Divergently Transcribed lncRNAs and Safeguards the T-mediated Mesodermal Commitment of Human PSCs
Authors: S Frank, G Ahuja, D Bartsch, N Russ, W Yao, JC Kuo, JP Derks, VS Akhade, Y Kargapolov, T Georgomano, JE Messling, M Gramm, L Brant, R Rehimi, NE Vargas, A Kuroczik, TP Yang, RGA Sahito, J Franzen, J Hescheler, A Sachinidis, M Peifer, A Rada-Igles, M Kanduri, IG Costa, C Kanduri, A Papantonis, L Kurian
Cell Stem Cell, 2018;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: ICC -
Derivation and characterization of the NIH registry human stem cell line NYSCF100 line under defined feeder-free conditions
Authors: A Sevilla, E Forero, M Zimmer, H Martinez, K Reggio, D Paull, D Egli, S Noggle
Stem Cell Res, 2018;29(0):99-102.
Species: Human
Sample Types: Whole Cells
Applications: IHC -
A hPSC-based platform to discover gene-environment interactions that impact human ?-cell and dopamine neuron survival
Authors: T Zhou, TW Kim, CN Chong, L Tan, S Amin, Z Sadat Badi, S Mukherjee, Z Ghazizadeh, H Zeng, M Guo, M Crespo, T Zhang, R Kenyon, CL Robinson, E Apostolou, H Wang, JZ Xiang, T Evans, L Studer, S Chen
Nat Commun, 2018;9(1):4815.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of two induced pluripotent stem cells lines from a Mucopolysaccharydosis IIIB (MPSIIIB) patient
Authors: S Vallejo-Di, A Fleischer, JM Martín-Fer, A Sánchez-Gi, D Bachiller
Stem Cell Res, 2018;33(0):180-184.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Three lines of induced pluripotent stem cells derived from a 15q11.2-q13.1 duplication syndrome patient
Authors: Y Arioka, I Kushima, D Mori, N Ozaki
Stem Cell Res, 2018;31(0):240-243.
Species: Human
Sample Types: Whole Tissue
Applications: IHC -
Derivation of induced pluripotent stem cells in Japanese macaque (Macaca fuscata)
Authors: R Nakai, M Ohnuki, K Kuroki, H Ito, H Hirai, R Kitajima, T Fujimoto, M Nakagawa, W Enard, M Imamura
Sci Rep, 2018;8(1):12187.
Species: Primate - Macaca mulatta (Rhesus Macaque)
Sample Types: Whole Cells
Applications: ICC -
Generation of an induced pluripotent stem cell line from a hypertrophic cardiomyopathy patient with a pathogenic myosin binding protein C (MYBPC3) p.Arg502Trp mutation
Authors: M Holliday, SB Ross, S Lim, C Semsarian
Stem Cell Res, 2018;33(0):56-59.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
WNT signaling memory is required for ACTIVIN to function as a morphogen in human gastruloids
Authors: A Yoney, F Etoc, A Ruzo, T Carroll, JJ Metzger, I Martyn, S Li, C Kirst, ED Siggia, AH Brivanlou
Elife, 2018;7(0):.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Esrrb Unlocks Silenced Enhancers for Reprogramming to Naive Pluripotency
Authors: K Adachi, W Kopp, G Wu, S Heising, B Greber, M Stehling, MJ Araúzo-Bra, ST Boerno, B Timmermann, M Vingron, HR Schöler
Cell Stem Cell, 2018;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: IHC -
Short-term retinoic acid treatment sustains pluripotency and suppresses differentiation of human induced pluripotent stem cells
Authors: MT De Angelis, EI Parrotta, G Santamaria, G Cuda
Cell Death Dis, 2018;9(1):6.
Species: Human
Sample Types: Embryoid Bodies
Applications: ICC -
Coordinated Control of mRNA and rRNA Processing Controls Embryonic Stem Cell Pluripotency and Differentiation
Authors: NS Corsini, AM Peer, P Moeseneder, M Roiuk, TR Burkard, HC Theussl, I Moll, JA Knoblich
Cell Stem Cell, 2018;22(4):543-558.e12.
Species: Mouse
Sample Types: Whole Cells
Applications: ICC -
SOX17 regulates uterine epithelial-stromal cross-talk acting via a distal enhancer upstream of Ihh
Authors: X Wang, X Li, T Wang, SP Wu, JW Jeong, TH Kim, SL Young, BA Lessey, RB Lanz, JP Lydon, FJ DeMayo
Nat Commun, 2018;9(1):4421.
Species: Mouse
Sample Types: Tissue Homogenates
Applications: Immunoprecipitation -
Generation of two induced pluripotent stem cell (iPSC) lines from p.F508del Cystic Fibrosis patients
Authors: A Fleischer, IM Lorenzo, E Palomino, T Aasen, F Gómez, M Servera, VJ Asensio, V Gálvez, JC Izpisúa-Be, D Bachiller
Stem Cell Res, 2018;29(0):1-5.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Random Mutagenesis, Clonal Events, and Embryonic or Somatic Origin Determine the mtDNA Variant Type and Load in Human Pluripotent Stem�Cells
Authors: F Zambelli, J Mertens, D Dziedzicka, J Sterckx, C Markouli, A Keller, P Tropel, L Jung, S Viville, H Van de Vel, M Geens, S Seneca, K Sermon, C Spits
Stem Cell Reports, 2018;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Sox7 promotes high-grade glioma by increasing VEGFR2-mediated vascular abnormality
Authors: IK Kim, K Kim, E Lee, DS Oh, CS Park, S Park, JM Yang, JH Kim, HS Kim, DT Shima, JH Kim, SH Hong, YH Cho, YH Kim, JB Park, GY Koh, YS Ju, HK Lee, S Lee, I Kim
J. Exp. Med., 2018;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: IHC-P -
Establishment of STUB1/CHIP mutant induced pluripotent stem cells (iPSCs) from a patient with Gordon Holmes syndrome/SCAR16
Authors: S Schuster, Y Schelling, M Synofzik, P Höflinger, L Schöls, S Hauser
Stem Cell Res, 2018;29(0):166-169.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Induced pluripotent stem cells derived from a schizophrenia patient with ASTN2 deletion
Authors: Y Arioka, I Kushima, H Kubo, D Mori, N Ozaki
Stem Cell Res, 2018;30(0):81-84.
Species: Human
Sample Types: Whole Cells
Applications: IHC -
G9a regulates temporal preimplantation developmental program and lineage segregation in blastocyst
Authors: JJ Zylicz, M Borensztei, FC Wong, Y Huang, C Lee, S Dietmann, MA Surani
Elife, 2018;7(0):.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
Mapping the Mouse Cell Atlas by Microwell-Seq
Authors: X Han, R Wang, Y Zhou, L Fei, H Sun, S Lai, A Saadatpour, Z Zhou, H Chen, F Ye, D Huang, Y Xu, W Huang, M Jiang, X Jiang, J Mao, Y Chen, C Lu, J Xie, Q Fang, Y Wang, R Yue, T Li, H Huang, SH Orkin, GC Yuan, M Chen, G Guo
Cell, 2018;172(5):1091-1107.e17.
Species: Mouse
Sample Types: Whole Cells
Applications: ICC -
Generation of gene-corrected iPSC line from Parkinson's disease patient iPSC line with alpha-SNCA A53T mutation
Authors: SY Lee, S Jeong, J Kim, SK Chung
Stem Cell Res, 2018;30(0):145-149.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Novel SOX17 frameshift mutations in endometrial cancer are functionally distinct from recurrent missense mutations
Authors: CJ Walker, MJ O'Hern, VA Serna, T Kurita, MA Miranda, CE Sapp, DG Mutch, DE Cohn, PJ Goodfellow
Oncotarget, 2017;8(40):68758-68768.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot -
Guided self-organization and cortical plate formation in human brain organoids
Authors: MA Lancaster, NS Corsini, S Wolfinger, EH Gustafson, AW Phillips, TR Burkard, T Otani, FJ Livesey, JA Knoblich
Nat. Biotechnol., 2017;0(0):.
Species: Human
Sample Types: Whole Tissue
Applications: IHC -
Lymphoblast-derived integration-free ISRM-CON9 iPS cell line from a 75year old female
Authors: S Martins, M Bohndorf, F Schröter, F Assar, W Wruck, K Sleegers, C Van Broeck, J Adjaye
Stem Cell Res, 2017;26(0):76-79.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
An Activating STAT3 Mutation Causes Neonatal Diabetes through Premature Induction of Pancreatic Differentiation
Authors: J Saarimäki-, D Balboa, MA Russell, J Saarikettu, M Kinnunen, S Keskitalo, A Malhi, C Valensisi, C Andrus, S Eurola, H Grym, J Ustinov, K Wartiovaar, RD Hawkins, O Silvennoin, M Varjosalo, NG Morgan, T Otonkoski
Cell Rep, 2017;19(2):281-294.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Lineage Establishment and Progression within the Inner Cell Mass of the Mouse Blastocyst Requires FGFR1 and FGFR2
Authors: M Kang, V Garg, AK Hadjantona
Dev. Cell, 2017;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: ICC -
ICM conversion to epiblast by FGF/ERK inhibition is limited in time and requires transcription and protein degradation
Authors: S Bessonnard, S Coqueran, S Vandormael, A Dufour, J Artus, M Cohen-Tann
Sci Rep, 2017;7(1):12285.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
Acellular Mouse Kidney ECM can be Used as a Three-Dimensional Substrate to Test the Differentiation Potential of Embryonic Stem Cell Derived Renal Progenitors
Authors: M Sambi, T Chow, J Whiteley, M Li, S Chua, V Raileanu, IM Rogers
Stem Cell Rev, 2017;0(0):.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
Peripheral blood derived induced pluripotent stem cells (iPSCs) from a female with familial hypertrophic cardiomyopathy
Authors: SB Ross, ST Fraser, RD Bagnall, C Semsarian
Stem Cell Res, 2017;20(0):76-79.
Species: Human
Sample Types: Whole Tissue
Applications: IHC -
The chromatin modifier Satb1 regulates cell fate through Fgf signalling in the early mouse embryo
Authors: M Goolam, M Zernicka-G
Development, 2017;0(0):.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
Direct Reprogramming of Fibroblasts via a Chemically Induced XEN-like State
Authors: X Li, D Liu, Y Ma, X Du, J Jing, L Wang, B Xie, D Sun, S Sun, X Jin, X Zhang, T Zhao, J Guan, Z Yi, W Lai, P Zheng, Z Huang, Y Chang, Z Chai, J Xu, H Deng
Cell Stem Cell, 2017;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: ICC -
Directed differentiation of human induced pluripotent stem cells into functional cholangiocyte-like cells
Authors: F Sampazioti, MC de Brito, I Geti, A Bertero, NR Hannan, L Vallier
Nat Protoc, 2017;12(4):814-827.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Accreditation of Biosafe Clinical-Grade Human Embryonic Stem Cells According to Chinese Regulations
Authors: Q Gu, J Wang, L Wang, ZX Liu, WW Zhu, YQ Tan, WF Han, J Wu, CJ Feng, JH Fang, L Liu, L Wang, W Li, XY Zhao, BY Hu, J Hao, Q Zhou
Stem Cell Reports, 2017;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Xist-dependent imprinted X inactivation and the early developmental consequences of its failure
Authors: M Borensztei, L Syx, K Ancelin, P Diabangoua, C Picard, T Liu, JB Liang, I Vassilev, R Galupa, N Servant, E Barillot, A Surani, CJ Chen, E Heard
Nat. Struct. Mol. Biol, 2017;0(0):.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
Rapid DNA replication origin licensing protects stem cell pluripotency
Authors: JP Matson, R Dumitru, P Coryell, RM Baxley, W Chen, K Twaroski, BR Webber, J Tolar, AK Bielinsky, JE Purvis, JG Cook
Elife, 2017;6(0):.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
TALEN-mediated shift of mitochondrial DNA heteroplasmy in MELAS-iPSCs with m.13513G>A mutation
Authors: N Yahata, Y Matsumoto, M Omi, N Yamamoto, R Hata
Sci Rep, 2017;7(1):15557.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Human iPSC-Derived Neural Progenitors Are an Effective Drug Discovery Model for Neurological mtDNA Disorders
Authors: C Lorenz, P Lesimple, R Bukowiecki, A Zink, G Inak, B Mlody, M Singh, M Semtner, N Mah, K Aur‚, M Leong, O Zabiegalov, EM Lyras, V Pfiffer, B Fauler, J Eichhorst, B Wiesner, N Huebner, J Priller, T Mielke, D Meierhofer, Z Izsv k, JC Meier, F Bouillaud, J Adjaye, M Schuelke, EE Wanker, A LombŠs, A Prigione
Cell Stem Cell, 2017;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Distinct Requirements for FGFR1 and FGFR2 in Primitive Endoderm Development and Exit from Pluripotency
Authors: A Molotkov, P Mazot, JR Brewer, RM Cinalli, P Soriano
Dev. Cell, 2017;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: ICC -
Generation of induced pluripotent stem cells (iPSCs) from a hypertrophic cardiomyopathy patient with the pathogenic variant p.Val698Ala in beta-myosin heavy chain (MYH7) gene
Authors: SB Ross, ST Fraser, N Nowak, C Semsarian
Stem Cell Res, 2017;20(0):88-90.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Identification of a small molecule that facilitates the differentiation of human iPSCs/ESCs and mouse embryonic pancreatic explants into pancreatic endocrine cells
Authors: Y Kondo, T Toyoda, R Ito, M Funato, Y Hosokawa, S Matsui, T Sudo, M Nakamura, C Okada, X Zhuang, A Watanabe, A Ohta, N Inagaki, K Osafune
Diabetologia, 2017;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of a PXR reporter human induced pluripotent stem cell line (PXR-mCherry hiPSC) using the CRISPR/Cas9 system
Authors: H Kim, JW Kim, SJ Kim, YJ Choi, DS Kim, HJ Park
Stem Cell Res, 2017;26(0):72-75.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Embryonic cholecystitis and defective gallbladder contraction in the Sox17-haploinsufficient model of biliary atresia
Authors: H Higashiyam, A Ozawa, H Sumitomo, M Uemura, K Fujino, H Igarashi, K Imaimatsu, N Tsunekawa, Y Hirate, M Kurohmaru, Y Saijoh, M Kanai-Azum, Y Kanai
Development, 2017;0(0):.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
Dynamics of 5-carboxylcytosine during hepatic differentiation: potential general role for active demethylation by DNA repair in lineage specification
Authors: LC Lewis, PC Lo, JM Foster, N Dai, IR Corrêa, PM Durczak, G Duncan, A Ramsawhook, GP Aithal, C Denning, NR Hannan, A Ruzov
Epigenetics, 2017;0(0):0.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Activation of the Aryl Hydrocarbon Receptor Interferes with Early Embryonic Development
Authors: M Gialitakis, M Tolaini, Y Li, M Pardo, L Yu, A Toribio, JS Choudhary, K Niakan, V Papayannop, B Stockinger
Stem Cell Reports, 2017;9(5):1377-1386.
Species: Mouse
Sample Types: Embryo
Applications: IHC-Fr -
Insulin-producing cells derived from 'induced pluripotent stem cells' of patients with fulminant type 1 diabetes: vulnerability to cytokine insults and increased expression of apoptosis-related genes
Authors: Y Hosokawa, T Toyoda, K Fukui, MY Baden, M Funato, Y Kondo, T Sudo, H Iwahashi, M Kishida, C Okada, A Watanabe, I Asaka, K Osafune, A Imagawa, I Shimomura
J Diabetes Investig, 2017;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Plasticity of the inner cell mass in mouse blastocyst is restricted by the activity of FGF/MAPK pathway
Authors: M Wigger, K Kisielewsk, K Filimonow, B Plusa, M Maleszewsk, A Suwi?ska
Sci Rep, 2017;7(1):15136.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
Functional Thyroid Follicular Cells Differentiation from Human-Induced Pluripotent Stem Cells in Suspension Culture
Authors: A Arauchi, K Matsuura, T Shimizu, T Okano
Front Endocrinol (Lausanne), 2017;8(0):103.
Species: Human
Sample Types: Embryoid Bodies
Applications: Flow Cytometry -
The circular RNA circBIRC6 participates in the molecular circuitry controlling human pluripotency
Authors: CY Yu, TC Li, YY Wu, CH Yeh, W Chiang, CY Chuang, HC Kuo
Nat Commun, 2017;8(1):1149.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Principles of early human development and germ cell program from conserved model systems
Authors: T Kobayashi, H Zhang, WWC Tang, N Irie, S Withey, D Klisch, A Sybirna, S Dietmann, DA Contreras, R Webb, C Allegrucci, R Alberio, MA Surani
Nature, 2017;546(7658):416-420.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot -
Capturing the biology of disease severity in a PSC-based model of familial dysautonomia
Authors: N Zeltner, F Fattahi, NC Dubois, N Saurat, F Lafaille, L Shang, B Zimmer, J Tchieu, MA Soliman, G Lee, JL Casanova, L Studer
Nat. Med., 2016;22(12):1421-1427.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Ductular reaction-on-a-chip: Microfluidic co-cultures to study stem cell fate selection during liver injury
Sci Rep, 2016;6(0):36077.
Species: Rat
Sample Types: Whole Cells
Applications: IHC -
Efficient derivation of extraembryonic endoderm stem cell lines from mouse postimplantation embryos
Sci Rep, 2016;6(0):39457.
Species: Mouse
Sample Types: Whole Cells
Applications: ICC -
Diverse Functions of Retinoic Acid in Brain Vascular Development
J Neurosci, 2016;36(29):7786-801.
Species: Human
Sample Types: Whole Tissue
Applications: IHC-Fr -
p38 (Mapk14/11) occupies a regulatory node governing entry into primitive endoderm differentiation during preimplantation mouse embryo development
Open Biol, 2016;6(9):.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
Hepatic differentiation of human pluripotent stem cells in miniaturized format suitable for high-throughput screen
Authors: A Carpentier, I Nimgaonkar, V Chu, Y Xia, Z Hu, TJ Liang
Stem Cell Res, 2016;16(3):640-650.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Derivation of Patient Specific Pluripotent Stem Cells Using Clinically Discarded Cumulus Cells
PLoS ONE, 2016;11(11):e0165715.
Species: Human
Sample Types: Whole Cells
Applications: IHC-P -
Selection and dynamics of embryonic stem cell integration into early mouse embryos.
Authors: Alexandrova S, Kalkan T, Humphreys P, Riddell A, Scognamiglio R, Trumpp A, Nichols J
Development, 2016;143(1):24-34.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
Generation of optic atrophy 1 patient-derived induced pluripotent stem cells (iPS-OPA1-BEHR) for disease modeling of complex optic atrophy syndromes (Behr syndrome)
Stem Cell Res, 2016;17(2):426-429.
Species: Human
Sample Types: Whole Cells
Applications: IHC-Fr -
Inappropriate cadherin switching in the mouse epiblast compromises proper signaling between the epiblast and the extraembryonic ectoderm during gastrulation
Sci Rep, 2016;6(0):26562.
Species: Mouse
Sample Types: Whole Cells
Applications: IHC -
Changes in Parthenogenetic Imprinting Patterns during Reprogramming by Cell Fusion
Authors: Hyun Sik Jang
PLoS ONE, 2016;11(5):e0156491.
Species: Mouse
Sample Types: Whole Cells
Applications: IHC -
The Anterior-Posterior Patterning of Definitive Endoderm Generated from Human Embryonic Stem Cells Depends on the Differential Signaling of Retinoic Acid, Wnt- and BMP-Signaling
Authors: Claudia Davenport
Stem Cells, 2016;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: IHC -
Automated, high-throughput derivation, characterization and differentiation of induced pluripotent stem cells.
Authors: Paull D, Sevilla A, Zhou H, Hahn A, Kim H, Napolitano C, Tsankov A, Shang L, Krumholz K, Jagadeesan P, Woodard C, Sun B, Vilboux T, Zimmer M, Forero E, Moroziewicz D, Martinez H, Malicdan M, Weiss K, Vensand L, Dusenberry C, Polus H, Sy K, Kahler D, Gahl W, Solomon S, Chang S, Meissner A, Eggan K, Noggle S
Nat Methods, 2015;12(9):885-92.
Species: Human
Sample Types: Whole Cells
Applications: IHC -
Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis.
Authors: Takasato M, Er P, Chiu H, Maier B, Baillie G, Ferguson C, Parton R, Wolvetang E, Roost M, Chuva de Sousa Lopes S, Little M
Nature, 2015;526(7574):564-8.
Species: Human
Sample Types: Whole Tissue
Applications: IHC -
Design of a Vitronectin-Based Recombinant Protein as a Defined Substrate for Differentiation of Human Pluripotent Stem Cells into Hepatocyte-Like Cells.
Authors: Nagaoka M, Kobayashi M, Kawai C, Mallanna S, Duncan S
PLoS ONE, 2015;10(8):e0136350.
Species: Human
Sample Types: Whole Cells
Applications: IHC -
HEB associates with PRC2 and SMAD2/3 to regulate developmental fates.
Authors: Yoon, Se-Jin, Foley, Joseph W, Baker, Julie C
Nat Commun, 2015;6(0):6546.
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot -
Activin-A and Bmp4 levels modulate cell type specification during CHIR-induced cardiomyogenesis.
Authors: Kim M, Horst A, Blinka S, Stamm K, Mahnke D, Schuman J, Gundry R, Tomita-Mitchell A, Lough J
PLoS ONE, 2015;10(2):e0118670.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Transcription activator-like effector nuclease (TALEN)-mediated CLYBL targeting enables enhanced transgene expression and one-step generation of dual reporter human induced pluripotent stem cell (iPSC) and neural stem cell (NSC) lines.
Authors: Cerbini T, Funahashi R, Luo Y, Liu C, Park K, Rao M, Malik N, Zou J
PLoS ONE, 2015;10(1):e0116032.
Species: Human
Sample Types: Whole Cells
Applications: IHC -
BMP signalling regulates the pre-implantation development of extra-embryonic cell lineages in the mouse embryo.
Authors: Graham, Sarah J, Wicher, Krzyszto, Jedrusik, Agnieszk, Guo, Guoji, Herath, Wishva, Robson, Paul, Zernicka-Goetz, Magdalen
Nat Commun, 2014;5(0):5667.
Species: Mouse
Sample Types: Whole Cells
Applications: ICC -
Derivation of transgene-free human induced pluripotent stem cells from human peripheral T cells in defined culture conditions.
Authors: Kishino, Yoshikaz, Seki, Tomohisa, Fujita, Jun, Yuasa, Shinsuke, Tohyama, Shugo, Kunitomi, Akira, Tabei, Ryota, Nakajima, Kazuaki, Okada, Marina, Hirano, Akinori, Kanazawa, Hideaki, Fukuda, Keiichi
PLoS ONE, 2014;9(5):e97397.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Citrullination regulates pluripotency and histone H1 binding to chromatin.
Authors: Christophorou M, Castelo-Branco G, Halley-Stott R, Oliveira C, Loos R, Radzisheuskaya A, Mowen K, Bertone P, Silva J, Zernicka-Goetz M, Nielsen M, Gurdon J, Kouzarides T
Nature, 2014;507(7490):104-8.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
Unfolded protein response is required for the definitive endodermal specification of mouse embryonic stem cells via Smad2 and beta-catenin signaling.
Authors: Xu H, Tsang K, Wang Y, Chan J, Xu G, Gao W
J Biol Chem, 2014;289(38):26290-301.
Species: Mouse
Sample Types: Whole Cells
Applications: IHC -
Generation and characterization of induced pluripotent stem cells from Aid-deficient mice.
Authors: Shimamoto R, Amano N, Ichisaka T, Watanabe A, Yamanaka S, Okita K
PLoS ONE, 2014;9(4):e94735.
Species: Mouse
Sample Types: Whole Cells
Applications: ICC -
A modified EpiSC culture condition containing a GSK3 inhibitor can support germline-competent pluripotency in mice.
Authors: Tsukiyama, Tomoyuki, Ohinata, Yasuhide
PLoS ONE, 2014;9(4):e95329.
Species: Mouse
Sample Types: Whole Cells
Applications: ICC -
Induction of pluripotency in human somatic cells via a transient state resembling primitive streak-like mesendoderm.
Authors: Takahashi K, Tanabe K, Ohnuki M, Narita M, Sasaki A, Yamamoto M, Nakamura M, Sutou K, Osafune K, Yamanaka S
Nat Commun, 2014;5(0):3678.
Species: Human
Sample Types: Whole Cells
Applications: IHC -
miR-373 is regulated by TGFbeta signaling and promotes mesendoderm differentiation in human Embryonic Stem Cells.
Authors: Rosa A, Papaioannou M, Krzyspiak J, Brivanlou A
Dev Biol, 2014;391(1):81-8.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
High oxygen condition facilitates the differentiation of mouse and human pluripotent stem cells into pancreatic progenitors and insulin-producing cells.
Authors: Hakim F, Kaitsuka T, Raeed J, Wei F, Shiraki N, Akagi T, Yokota T, Kume S, Tomizawa K
J Biol Chem, 2014;289(14):9623-38.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Discovery of directional and nondirectional pioneer transcription factors by modeling DNase profile magnitude and shape.
Authors: Sherwood, Richard, Hashimoto, Tatsunor, O'Donnell, Charles, Lewis, Sophia, Barkal, Amira A, van Hoff, John Pet, Karun, Vivek, Jaakkola, Tommi, Gifford, David K
Nat Biotechnol, 2014;32(2):171-8.
Species: Mouse
Sample Types: Whole Cells
Applications: ICC -
Generation of functional insulin-producing cells from mouse embryonic stem cells through 804G cell-derived extracellular matrix and protein transduction of transcription factors.
Authors: Kaitsuka T, Noguchi H, Shiraki N, Kubo T, Wei F, Hakim F, Kume S, Tomizawa K
Stem Cells Transl Med, 2014;3(1):114-27.
Species: Mouse
Sample Types: Whole Cells
Applications: ICC -
Efficient programming of human eye conjunctiva-derived induced pluripotent stem (ECiPS) cells into definitive endoderm-like cells.
Authors: Massumi M, Hoveizi E, Baktash P, Hooti A, Ghazizadeh L, Nadri S, Pourasgari F, Hajarizadeh A, Soleimani M, Nabiuni M, Khorramizadeh M
Exp Cell Res, 2014;322(1):51-61.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
GATA6 levels modulate primitive endoderm cell fate choice and timing in the mouse blastocyst.
Authors: Schrode N, Saiz N, Di Talia S, Hadjantonakis A
Dev Cell, 2014;29(4):454-67.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
Sox17-mediated maintenance of fetal intra-aortic hematopoietic cell clusters.
Authors: Nobuhisa I, Osawa M, Uemura M, Kishikawa Y, Anani M, Harada K, Takagi H, Saito K, Kanai-Azuma M, Kanai Y, Iwama A, Taga T
Mol Cell Biol, 2014;34(11):1976-90.
Species: Mouse
Sample Types: Embryo
Applications: IHC -
Identification of transcription factors for lineage-specific ESC differentiation.
Authors: Yamamizu K, Piao Y, Sharov A, Zsiros V, Yu H, Nakazawa K, Schlessinger D, Ko M
Stem Cell Reports, 2013;1(6):545-59.
-
Cell-cycle control of developmentally regulated transcription factors accounts for heterogeneity in human pluripotent cells.
Authors: Singh A, Chappell J, Trost R, Lin L, Wang T, Tang J, Matlock B, Weller K, Wu H, Zhao S, Jin P, Dalton S
Stem Cell Reports, 2013;1(6):532-44.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Production of hepatocyte-like cells from human pluripotent stem cells.
Authors: Hannan, Nicholas, Segeritz, Charis-P, Touboul, Thomas, Vallier, Ludovic
Nat Protoc, 2013;8(2):430-7.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Defined extracellular matrix components are necessary for definitive endoderm induction.
Authors: Taylor-Weiner H, Schwarzbauer J, Engler A
Stem Cells, 2013;31(10):2084-94.
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot -
A molecular signature for purified definitive endoderm guides differentiation and isolation of endoderm from mouse and human embryonic stem cells.
Authors: Wang P, McKnight K, Wong D, Rodriguez R, Sugiyama T, Gu X, Ghodasara A, Qu K, Chang H, Kim S
Stem Cells Dev, 2012;21(12):2273-87.
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot -
The endothelial cell line bEnd.3 maintains human pluripotent stem cells.
Authors: Joubin, Katherin, Richardson, Amelia, Novoa, Natalia, Tu, Edmund, Tomishima, Mark J
Stem Cells Dev, 2012;21(12):2312-21.
Species: Human
Sample Types: Whole Cells
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Self-renewal of embryonic-stem-cell-derived progenitors by organ-matched mesenchyme.
Authors: Sneddon, Julie B, Borowiak, Malgorza, Melton, Douglas
Nature, 2012;491(7426):765-8.
Species: Mouse
Sample Types: Whole Cells
Applications: ICC -
CD166(pos) subpopulation from differentiated human ES and iPS cells support repair of acute lung injury.
Authors: Soh, Boon Sen, Zheng, Dahai, Li Yeo, Julie Su, Yang, Henry He, Ng, Shi Yan, Wong, Lan Hion, Zhang, Wencai, Li, Pin, Nichane, Massimo, Asmat, Atasha, Wong, Poo Sing, Wong, Peng Che, Su, Lin Lin, Mantalaris, Sakis A, Lu, Jia, Xian, Wa, McKeon, Frank, Chen, Jianzhu, Lim, Elaine H, Lim, Bing
Mol Ther, 2012;20(12):2335-46.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
A novel chemically directed route for the generation of definitive endoderm from human embryonic stem cells based on inhibition of GSK-3.
Authors: Bone HK, Nelson AS, Goldring CE, Tosh D, Welham MJ
J. Cell. Sci., 2011;124(0):1992-2000.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
CD24: a novel surface marker for PDX1-positive pancreatic progenitors derived from human embryonic stem cells.
Authors: Jiang W, Sui X, Zhang D, Liu M, Ding M, Shi Y, Deng H
Stem Cells, 2011;29(4):609-17.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Early in vitro differentiation of mouse definitive endoderm is not correlated with progressive maturation of nuclear DNA methylation patterns.
Authors: Tajbakhsh J, Gertych A, Fagg WS
PLoS ONE, 2011;6(7):e21861.
Species: Mouse
Sample Types: Whole Cells
Applications: ICC -
Origin and formation of the first two distinct cell types of the inner cell mass in the mouse embryo.
Authors: Morris SA, Teo RT, Li H, Robson P, Glover DM, Zernicka-Goetz M
Proc. Natl. Acad. Sci. U.S.A., 2010;107(14):6364-9.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
The ROCK inhibitor Y-27632 improves recovery of human embryonic stem cells after fluorescence-activated cell sorting with multiple cell surface markers.
Authors: Emre N, Vidal JG, Elia J
PLoS ONE, 2010;5(8):e12148.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
SIP1 mediates cell-fate decisions between neuroectoderm and mesendoderm in human pluripotent stem cells.
Authors: Chng Z, Teo A, Pedersen RA, Vallier L
Cell Stem Cell, 2010;6(1):59-70.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
A role for PDGF signaling in expansion of the extra-embryonic endoderm lineage of the mouse blastocyst.
Authors: Artus J, Panthier JJ, Hadjantonakis AK
Development, 2010;137(20):3361-72.
Species: Mouse
Sample Types: Whole Cells
Applications: ICC -
Induction of pluripotent stem cells from human third molar mesenchymal stromal cells.
Authors: Oda Y, Yoshimura Y, Ohnishi H
J. Biol. Chem., 2010;285(38):29270-8.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Alginate microcapsule for propagation and directed differentiation of hESCs to definitive endoderm.
Authors: Chayosumrit M, Tuch B, Sidhu K
Biomaterials, 2010;31(3):505-14.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot -
Biphasic induction of Pdx1 in mouse and human embryonic stem cells can mimic development of pancreatic beta-cells.
Authors: Bernardo AS, Cho CH, Mason S, Docherty HM, Pedersen RA, Vallier L, Docherty K
Stem Cells, 2009;27(2):341-51.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Small molecules efficiently direct endodermal differentiation of mouse and human embryonic stem cells.
Authors: Borowiak M, Maehr R, Chen S, Chen AE, Tang W, Fox JL, Schreiber SL, Melton DA
Cell Stem Cell, 2009;4(4):348-58.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Vitronectin promotes oligodendrocyte differentiation during neurogenesis of human embryonic stem cells.
Authors: Gil JE, Woo DH, Shim JH, Kim SE, You HJ, Park SH, Paek SH, Kim SK, Kim JH
FEBS Lett., 2009;583(3):561-7.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Feeder-free derivation of induced pluripotent stem cells from adult human adipose stem cells.
Authors: Sun N, Panetta NJ, Gupta DM, Wilson KD, Lee A, Jia F, Hu S, Cherry AM, Robbins RC, Longaker MT, Wu JC
Proc. Natl. Acad. Sci. U.S.A., 2009;106(37):15720-5.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
A late requirement for Wnt and FGF signaling during activin-induced formation of foregut endoderm from mouse embryonic stem cells.
Authors: Hansson M, Olesen DR, Peterslund JM, Engberg N, Kahn M, Winzi M, Klein T, Maddox-Hyttel P, Serup P
Dev. Biol., 2009;330(2):286-304.
Species: Mouse
Sample Types: Whole Cells
Applications: ICC -
Highly efficient differentiation of human ES cells and iPS cells into mature pancreatic insulin-producing cells.
Authors: Zhang D, Jiang W, Liu M, Sui X, Yin X, Chen S, Shi Y, Deng H
Cell Res., 2009;19(4):429-38.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
High-throughput screening assay for the identification of compounds regulating self-renewal and differentiation in human embryonic stem cells.
Authors: Desbordes SC, Placantonakis DG, Ciro A, Socci ND, Lee G, Djaballah H, Studer L
Cell Stem Cell, 2008;2(6):602-12.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Prospective isolation and global gene expression analysis of definitive and visceral endoderm.
Authors: Sherwood RI, Jitianu C, Cleaver O, Shaywitz DA, Lamenzo JO, Chen AE, Golub TR, Melton DA
Dev. Biol., 2007;304(2):541-55.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
Long-term self-renewal and directed differentiation of human embryonic stem cells in chemically defined conditions.
Authors: Yao S, Chen S, Clark J, Hao E, Beattie GM, Hayek A, Ding S
Proc. Natl. Acad. Sci. U.S.A., 2006;103(18):6907-12.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of a human Ocular Albinism type 1 iPSC line, SEIi001-A, with a mutation in GPR143.
Authors: Baulier E, Garcia Diaz A, Corneo B, Farber D
Stem Cell Res, 0;33(0):274-277.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay
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Permeabilised with 0.5% Triton + 0.1% BSA
Blocked with 0.1% BSA/ 10% FCS as blocking agent for 1 hour at RT
Primary was added at 1:20 in blocking buffer and incubated o/n at 4oC.
SOX17 antibody was used to assess the efficient differentiation of hESCs towards Definitive endoderm
cells were fixed by adding 4%PFA for 15min
blocking buffer contained 10%FCS, 0.1% BSA in PBS
For permeabilisation 0.5% Triton X-100 was used
Antibody was used at 10mg/ml and left o/n at 4oC
Used this antibody to verify the endodermal germ layer derived from iPSC.