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Human SOX17 Antibody

AF1924 149 Citations 3 Reviews Datasheet / COA / SDS
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AF1924
AF1924-SP
Human SOX17 Antibody in Western Blot
6 Images
Product Details
Citations (149)
FAQs
Supplemental Products
Reviews (3)
Summary Data Examples Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human SOX17 Antibody Summary

Species Reactivity
Human
Specificity
Detects human SOX17 in direct ELISAs and Western blots. In direct ELISAs, less than 1% cross-reactivity with recombinant human (rh) SOX18 is observed.
Source
Polyclonal Goat IgG
Purification
Antigen Affinity-purified
Immunogen
E. coli-derived recombinant human SOX17
Asp177-Val414
Accession # Q9H6I2
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
Label
Unconjugated

Applications

Recommended Concentration
Sample
Western Blot
1 µg/mL
See below
Simple Western
10 µg/mL
See below
Chromatin Immunoprecipitation (ChIP)
5 µg/5 x 106 cells
See below
Immunocytochemistry
5-15 µg/mL
See below

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Data Examples

Western Blot Detection of Human SOX17 by Western Blot. View Larger

Detection of Human SOX17 by Western Blot. Western blot shows lysates of BG01V human embryonic stem cells untreated (-) or endoderm differentiated (+). PVDF membrane was probed with 1 µg/mL of Goat Anti-Human SOX17 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1924) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF109). A specific band was detected for SOX17 at approximately 55 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

Chromatin Immunoprecipitation (ChIP) Detection of SOX17-regulated Genes by Chromatin Immunoprecipitation. View Larger

Detection of SOX17-regulated Genes by Chromatin Immunoprecipitation. Endoderm-differentiated D3 mouse embryonic stem cell line was fixed using formaldehyde, resuspended in lysis buffer, and sonicated to shear chromatin. SOX17/DNA complexes were immunoprecipitated using 5 µg Goat Anti-Human SOX17 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1924) or control antibody (Catalog # AB-108-C) for 15 minutes in an ultrasonic bath, followed by Biotinylated Anti-Goat IgG Secondary Antibody (Catalog # BAF109). Immunocomplexes were captured using 50 µL of MagCellect Streptavidin Ferrofluid (Catalog # MAG999) and DNA was purified using chelating resin solution. Thep21promoter was detected by standard PCR.

Immunocytochemistry SOX17 in B16 Mouse Cell Line. View Larger

SOX17 in B16 Mouse Cell Line. SOX17 was detected in immersion fixed B16 mouse melanoma cell line using 10 µg/mL Goat Anti-Human SOX17 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1924) for 3 hours at room temperature. Cells were stained with the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red; Catalog # NL001) and counter-stained with DAPI (blue). View our protocol for Fluorescent ICC Staining of Cells on Coverslips.

Immunocytochemistry SOX17 in Human BG01V Cells. View Larger

SOX17 in Human BG01V Cells. SOX17 was detected in immersion fixed endoderm differentiated BG01V human embryonic stem cells using 10 µg/mL Goat Anti-Human SOX17 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1924) for 3 hours at room temperature. Cells were stained with the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red, upper panel; Catalog # NL001) and counterstained with DAPI (blue, lower panel). View our protocol for Fluorescent ICC Staining of Cells on Coverslips.

Simple Western Detection of Human SOX17 by Simple Western<SUP>TM</SUP>. View Larger

Detection of Human SOX17 by Simple WesternTM. Simple Western lane view shows lysates of BG01V human embryonic stem cells untreated (-) or endoderm differentiated (+), loaded at 0.2 mg/mL. A specific band was detected for SOX17 at approximately 59 kDa (as indicated) using 10 µg/mL of Goat Anti-Human SOX17 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1924) followed by 1:50 dilution of HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF109). This experiment was conducted under reducing conditions and using the 12-230 kDa separation system.

Simple Western Detection of Human SOX17 by Simple Western<sup>TM</sup>. View Larger

Detection of Human SOX17 by Simple WesternTM. Simple Western lane view shows lysates of iBJ6 human induced pluripotent stem cell line untreated (-) or endoderm differentiated (+), loaded at 0.2 mg/mL. A specific band was detected for SOX17 at approximately 58 kDa (as indicated) using 10 µg/mL of Goat Anti-Human SOX17 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1924) followed by 1:50 dilution of HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF109). This experiment was conducted under reducing conditions and using the 12-230 kDa separation system.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Reconstitution
Reconstitute at 0.2 mg/mL in sterile PBS.
Reconstitution Buffer Available
Reconstitution Buffer 1 (PBS)
Catalog #
Availability
Size / Price
Qty
RB01
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: SOX17

SOX17 is a member of the SOX family of transcription factors that bind DNA via a high mobility group (HMG) domain. SOX17 is suggested to play an important role in endoderm development (1, 2).

References
  1. Kanai-Azuma, M. et al. (2002) Development 129:2367.
  2. Katoh, M. et al. (2002) Int. J. Mol. Med. 9:153.
Long Name
Transcription Factor SOX17
Entrez Gene IDs
64321 (Human)
Alternate Names
FLJ22252; SOX17; SRY (sex determining region Y)-box 17; SRY-related HMG-box transcription factor SOX17; transcription factor SOX-17; VUR3

Product Datasheets

Product Datasheet
COA
SDS

Citations for Human SOX17 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

149 Citations: Showing 1 - 10
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  1. Comparative analysis of the mitochondrial morphology, energy metabolism, and gene expression signatures in three types of blastocyst-derived stem cells
    Authors: J Choi, BJ Seo, H La, SH Yoon, YJ Hong, JH Lee, HM Chung, K Hong, JT Do
    Redox Biol, 2020;30(0):101437.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  2. Multipotent RAG1+ progenitors emerge directly from haemogenic endothelium in human pluripotent stem cell-derived haematopoietic organoids
    Authors: A Motazedian, FF Bruveris, SV Kumar, JV Schiesser, T Chen, ES Ng, AP Chidgey, CA Wells, AG Elefanty, EG Stanley
    Nat. Cell Biol., 2020;22(1):60-73.
    Species: Mouse
    Sample Types: PSCs
    Applications: IF
  3. Single cell census of human kidney organoids shows reproducibility and diminished off-target cells after transplantation
    Authors: A Subramania, EH Sidhom, M Emani, K Vernon, N Sahakian, Y Zhou, M Kost-Alimo, M Slyper, J Waldman, D Dionne, LT Nguyen, A Weins, JL Marshall, O Rosenblatt, A Regev, A Greka
    Nat Commun, 2019;10(1):5462.
    Species: Mouse
    Sample Types: Organoid
    Applications: ICC
  4. Establishment and characterization of induced pluripotent stem cells (iPSCs) from central nervous system lupus erythematosus
    Authors: MT De Angelis, G Santamaria, EI Parrotta, S Scalise, M Lo Conte, S Gasparini, E Ferlazzo, U Aguglia, C Ciampi, A Sgura, G Cuda
    J. Cell. Mol. Med., 2019;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  5. Human induced pluripotent stem cell-derived vocal fold mucosa mimics development and responses to smoke exposure
    Authors: V Lungova, X Chen, Z Wang, C Kendziorsk, SL Thibeault
    Nat Commun, 2019;10(1):4161.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  6. Single-cell qPCR demonstrates that Repsox treatment changes cell fate from endoderm to neuroectoderm and disrupts epithelial-mesenchymal transition
    Authors: Q Li, Q Huang
    PLoS ONE, 2019;14(10):e0223724.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  7. Uterine SOX17: a key player in human endometrial receptivity and embryo implantation
    Authors: S Kinnear, LA Salamonsen, M Francois, V Harley, J Evans
    Sci Rep, 2019;9(1):15495.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  8. Circadian Entrainment Triggers Maturation of Human In�Vitro Islets
    Authors: JR Alvarez-Do, J Donaghey, N Rasouli, JHR Kenty, A Helman, J Charlton, JR Straubhaar, A Meissner, DA Melton
    Cell Stem Cell, 2019;26(1):108-122.e10.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  9. Generation of a NKX2.1 - p63 double transgenic knock-in reporter cell line from human induced pluripotent stem cells (MHHi006-A-4)
    Authors: N Drick, A Sahabian, P Pongpamorn, S Merkert, G Göhring, T Welte, U Martin, R Olmer
    Stem Cell Res, 2019;42(0):101659.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  10. Molecular determinants of nephron vascular specialization in the kidney
    Authors: DM Barry, EA McMillan, B Kunar, R Lis, T Zhang, T Lu, E Daniel, M Yokoyama, JM Gomez-Sali, A Sureshbabu, O Cleaver, A Di Lorenzo, ME Choi, J Xiang, D Redmond, SY Rabbany, T Muthukumar, S Rafii
    Nat Commun, 2019;10(1):5705.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  11. A versatile toolbox for knock-in gene targeting based on the Multisite Gateway technology
    Authors: S Yoshimatsu, T Sone, M Nakajima, T Sato, R Okochi, M Ishikawa, M Nakamura, E Sasaki, S Shiozawa, H Okano
    PLoS ONE, 2019;14(8):e0221164.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  12. Generation of eight human induced pluripotent stem cell lines from Parkinson's disease patients carrying familial mutations
    Authors: M Chen, M Maimaitili, SH Buchholdt, UB Jensen, F Febbraro, M Denham
    Stem Cell Res, 2019;42(0):101657.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  13. Generation of an induced pluripotent stem cell line (UBCi001-A) from a presymptomatic individual carrying the R418X progranulin gene mutation
    Authors: J Frew, X Wu, GY Hsiung, HH Feldman, IR Mackenzie, HB Nygaard
    Stem Cell Res, 2019;41(0):101582.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  14. Generation of gene-corrected iPSC line, KIOMi002-A, from Parkinson's disease patient iPSC with LRRK2 G2019S mutation using BAC-based homologous recombination
    Authors: SY Lee, SK Chung
    Stem Cell Res, 2019;41(0):101649.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  15. Generation of a knock-in MAP2-tdTomato reporter human embryonic stem cell line with inducible expression of NEUROG2/1 (NYGCe001-A)
    Authors: C Lu, NE Sanjana
    Stem Cell Res, 2019;41(0):101643.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  16. Generation of a homozygous HDAC6 knockout human embryonic stem cell line by CRISPR/Cas9 editing
    Authors: L Xie, J Huang, X Li, L Dai, X Lin, J Zhang, J Luo, W Zhang
    Stem Cell Res, 2019;41(0):101610.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  17. In vitro metabolic zonation through oxygen gradient on a chip
    Authors: F Tonon, GG Giobbe, A Zambon, C Luni, O Gagliano, A Floreani, G Grassi, N Elvassore
    Sci Rep, 2019;9(1):13557.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  18. Efficient generation of human primordial germ cell-like cells from pluripotent stem cells in a methylcellulose-based 3D system at large scale
    Authors: X Wang, T Liao, C Wan, X Yang, J Zhao, R Fu, Z Yao, Y Huang, Y Shi, G Chang, Y Zheng, F Luo, Z Liu, Y Wang, X Mao, XY Zhao
    PeerJ, 2019;6(0):e6143.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  19. Induced pluripotent stem cell line (INSAi001-A) from a Gaucher disease type 3 patient compound heterozygote for mutations in the GBA1 gene
    Authors: AJ Duarte, D Ribeiro, R Santos, L Moreira, J Bragança, O Amaral
    Stem Cell Res, 2019;41(0):101595.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  20. Chemically defined and xenogeneic-free differentiation of human pluripotent stem cells into definitive endoderm in 3D culture
    Authors: U Diekmann, H Wolling, R Dettmer, I Niwolik, O Naujok, FFR Buettner
    Sci Rep, 2019;9(1):996.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  21. Generation of human antral and fundic gastric organoids from pluripotent stem cells
    Authors: TR Broda, KW McCracken, JM Wells
    Nat Protoc, 2019;14(1):28-50.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  22. Generation of a human induced pluripotent stem cell line, BRCi001-A, derived from a patient with mucopolysaccharidosis type I
    Authors: M Suga, T Kondo, K Imamura, R Shibukawa, Y Okanishi, Y Sagara, K Tsukita, T Enami, M Furujo, K Saijo, Y Nakamura, M Osawa, MK Saito, S Yamanaka, H Inoue
    Stem Cell Res, 2019;36(0):101406.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  23. Histone H3K9 Methyltransferase G9a in Oocytes Is Essential for Preimplantation Development but Dispensable for CG Methylation Protection
    Authors: WK Au Yeung, J Brind'Amou, Y Hatano, K Yamagata, R Feil, MC Lorincz, M Tachibana, Y Shinkai, H Sasaki
    Cell Rep, 2019;27(1):282-293.e4.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  24. The BAF and PRC2 Complex Subunits Dpf2 and Eed Antagonistically Converge on Tbx3 to Control ESC Differentiation
    Authors: W Zhang, C Chronis, X Chen, H Zhang, R Spalinskas, M Pardo, L Chen, G Wu, Z Zhu, Y Yu, L Yu, J Choudhary, J Nichols, MM Parast, B Greber, P Sahlén, K Plath
    Cell Stem Cell, 2019;24(1):138-152.e8.
    Species: Mouse
    Sample Types: Cell Lysates
    Applications: Western Blot
  25. Characterization of the first induced pluripotent stem cell line generated from a patient with autosomal dominant catecholaminergic polymorphic ventricular tachycardia due to a heterozygous mutation in cardiac calsequestrin-2
    Authors: S Ross, M Holliday, S Lim, C Semsarian
    Stem Cell Res, 2019;37(0):101450.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  26. Single-Cell RNA-Sequencing-Based CRISPRi Screening Resolves Molecular Drivers of Early Human Endoderm Development
    Authors: RMJ Genga, EM Kernfeld, KM Parsi, TJ Parsons, MJ Ziller, R Maehr
    Cell Rep, 2019;27(3):708-718.e10.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  27. Novel hybrid three-dimensional artificial liver using human induced pluripotent stem cells and a rat decellularized liver scaffold
    Authors: T Minami, T Ishii, K Yasuchika, K Fukumitsu, S Ogiso, Y Miyauchi, H Kojima, T Kawai, R Yamaoka, Y Oshima, H Kawamoto, M Kotaka, K Yasuda, K Osafune, S Uemoto
    Regen Ther, 2019;10(0):127-133.
    Species: Human
    Sample Types: Liver hiPSCs
    Applications: ICC
  28. Generation of one iPSC line (IMEDEAi006-A) from an early-onset familial Alzheimer's Disease (fAD) patient carrying the E280A mutation in the PSEN1 gene
    Authors: S Vallejo-Di, A Fleischer, JM Martín-Fer, A Sánchez-Gi, M Castresana, D Aguillón, A Villegas, CA Mastronard, LG Espinosa, M Arcos-Burg, Á Del Pozo, E Herrán, E Gainza, M Isaza-Ruge, F Lopera, D Bachiller
    Stem Cell Res, 2019;37(0):101440.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  29. The use of simultaneous reprogramming and gene correction to generate an osteogenesis imperfecta patient COL1A1 c. 3936 G>T iPSC line and an isogenic control iPSC line
    Authors: S Howden, H Hosseini F, A Motazedian, AG Elefanty, EG Stanley, SR Lamandé, JF Bateman
    Stem Cell Res, 2019;38(0):101453.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  30. Generation of a heterozygous COL1A1 (c.3969_3970insT) osteogenesis imperfecta mutation human iPSC line, MCRIi001-A-1, using CRISPR/Cas9 editing
    Authors: H Hosseini F, YN Patria, A Motazedian, AG Elefanty, EG Stanley, SR Lamandé, JF Bateman
    Stem Cell Res, 2019;37(0):101449.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  31. Loss of Cubilin, the intrinsic factor-vitamin B12 receptor, impairs visceral endoderm endocytosis and endodermal patterning in the mouse
    Authors: A Perea-Gome, O Cases, V Lelièvre, MV Pulina, J Collignon, AK Hadjantona, R Kozyraki
    Sci Rep, 2019;9(1):10168.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  32. SMYD2 Drives Mesendodermal Differentiation of Human Embryonic Stem Cells through Mediating the Transcriptional Activation of Key Mesendodermal Genes
    Authors: HJ Bai, P Zhang, L Ma, H Liang, G Wei, HT Yang
    Stem Cells, 2019;0(0):.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  33. Generation of an induced pluripotent stem cell line (GIBHi003-A) from a Parkinson's disease patient with mutant PINK1 (p. I368N)
    Authors: MM Abdul, DP Ibañez, P Zhao, H Liu, X Zhong, Y Li, M Zhang, W Li, Y Li, C Ward, S Chen, D Wang, B Qin, MA Esteban, X Wang, W Fan, Z Luo
    Stem Cell Res, 2019;41(0):101607.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  34. Regulatory pathways governing murine coronary vessel formation are dysregulated in the injured adult heart
    Authors: S Payne, M Gunadasa-R, A Neal, AN Redpath, J Patel, KM Chouliaras, I Ratnayaka, N Smart, S De Val
    Nat Commun, 2019;10(1):3276.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  35. Generation of Mouse Parthenogenetic Epiblast Stem Cells and Their Imprinting Patterns
    Authors: BJ Seo, HS Jang, H Song, C Park, K Hong, JW Lee, JT Do
    Int J Mol Sci, 2019;20(21):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  36. Dissecting the dynamics of signaling events in the BMP, WNT, and NODAL cascade during self-organized fate patterning in human gastruloids
    Authors: S Chhabra, L Liu, R Goh, X Kong, A Warmflash
    PLoS Biol., 2019;17(10):e3000498.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  37. Wnt Inhibition Facilitates RNA-Mediated Reprogramming of Human Somatic Cells to Naive Pluripotency
    Authors: N Bredenkamp, J Yang, J Clarke, GG Stirparo, F von Meyenn, S Dietmann, D Baker, R Drummond, Y Ren, D Li, C Wu, M Rostovskay, S Eminli-Mei, A Smith, G Guo
    Stem Cell Reports, 2019;13(6):1083-1098.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  38. Random Mutagenesis, Clonal Events, and Embryonic or Somatic Origin Determine the mtDNA Variant Type and Load in Human Pluripotent Stem�Cells
    Authors: F Zambelli, J Mertens, D Dziedzicka, J Sterckx, C Markouli, A Keller, P Tropel, L Jung, S Viville, H Van de Vel, M Geens, S Seneca, K Sermon, C Spits
    Stem Cell Reports, 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  39. Three lines of induced pluripotent stem cells derived from a 15q11.2-q13.1 duplication syndrome patient
    Authors: Y Arioka, I Kushima, D Mori, N Ozaki
    Stem Cell Res, 2018;31(0):240-243.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  40. A hPSC-based platform to discover gene-environment interactions that impact human ?-cell and dopamine neuron survival
    Authors: T Zhou, TW Kim, CN Chong, L Tan, S Amin, Z Sadat Badi, S Mukherjee, Z Ghazizadeh, H Zeng, M Guo, M Crespo, T Zhang, R Kenyon, CL Robinson, E Apostolou, H Wang, JZ Xiang, T Evans, L Studer, S Chen
    Nat Commun, 2018;9(1):4815.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  41. Generation of two induced pluripotent stem cells lines from a Mucopolysaccharydosis IIIB (MPSIIIB) patient
    Authors: S Vallejo-Di, A Fleischer, JM Martín-Fer, A Sánchez-Gi, D Bachiller
    Stem Cell Res, 2018;33(0):180-184.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  42. Generation of two induced pluripotent stem cell (iPSC) lines from p.F508del Cystic Fibrosis patients
    Authors: A Fleischer, IM Lorenzo, E Palomino, T Aasen, F Gómez, M Servera, VJ Asensio, V Gálvez, JC Izpisúa-Be, D Bachiller
    Stem Cell Res, 2018;29(0):1-5.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  43. Esrrb Unlocks Silenced Enhancers for Reprogramming to Naive Pluripotency
    Authors: K Adachi, W Kopp, G Wu, S Heising, B Greber, M Stehling, MJ Araúzo-Bra, ST Boerno, B Timmermann, M Vingron, HR Schöler
    Cell Stem Cell, 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: IHC
  44. Short-term retinoic acid treatment sustains pluripotency and suppresses differentiation of human induced pluripotent stem cells
    Authors: MT De Angelis, EI Parrotta, G Santamaria, G Cuda
    Cell Death Dis, 2018;9(1):6.
    Species: Human
    Sample Types: Embryoid Bodies
    Applications: ICC
  45. yylncT Defines a Class of Divergently Transcribed lncRNAs and Safeguards the T-mediated Mesodermal Commitment of Human PSCs
    Authors: S Frank, G Ahuja, D Bartsch, N Russ, W Yao, JC Kuo, JP Derks, VS Akhade, Y Kargapolov, T Georgomano, JE Messling, M Gramm, L Brant, R Rehimi, NE Vargas, A Kuroczik, TP Yang, RGA Sahito, J Franzen, J Hescheler, A Sachinidis, M Peifer, A Rada-Igles, M Kanduri, IG Costa, C Kanduri, A Papantonis, L Kurian
    Cell Stem Cell, 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  46. Generation of gene-corrected iPSC line from Parkinson's disease patient iPSC line with alpha-SNCA A53T mutation
    Authors: SY Lee, S Jeong, J Kim, SK Chung
    Stem Cell Res, 2018;30(0):145-149.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  47. Generation of an induced pluripotent stem cell line from a hypertrophic cardiomyopathy patient with a pathogenic myosin binding protein C (MYBPC3) p.Arg502Trp mutation
    Authors: M Holliday, SB Ross, S Lim, C Semsarian
    Stem Cell Res, 2018;33(0):56-59.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  48. WNT signaling memory is required for ACTIVIN to function as a morphogen in human gastruloids
    Authors: A Yoney, F Etoc, A Ruzo, T Carroll, JJ Metzger, I Martyn, S Li, C Kirst, ED Siggia, AH Brivanlou
    Elife, 2018;7(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  49. Generation of a homozygous CRISPR/Cas9-mediated knockout human iPSC line for the STUB1 locus
    Authors: S Schuster, S Saravanaku, L Schöls, S Hauser
    Stem Cell Res, 2018;34(0):101378.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  50. SOX17 regulates uterine epithelial-stromal cross-talk acting via a distal enhancer upstream of Ihh
    Authors: X Wang, X Li, T Wang, SP Wu, JW Jeong, TH Kim, SL Young, BA Lessey, RB Lanz, JP Lydon, FJ DeMayo
    Nat Commun, 2018;9(1):4421.
    Species: Mouse
    Sample Types: Tissue Homogenates
    Applications: Immunoprecipitation
  51. Establishment of STUB1/CHIP mutant induced pluripotent stem cells (iPSCs) from a patient with Gordon Holmes syndrome/SCAR16
    Authors: S Schuster, Y Schelling, M Synofzik, P Höflinger, L Schöls, S Hauser
    Stem Cell Res, 2018;29(0):166-169.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  52. Induced pluripotent stem cells derived from a schizophrenia patient with ASTN2 deletion
    Authors: Y Arioka, I Kushima, H Kubo, D Mori, N Ozaki
    Stem Cell Res, 2018;30(0):81-84.
    Species: Human
    Sample Types: Whole Cells
    Applications: IHC
  53. G9a regulates temporal preimplantation developmental program and lineage segregation in blastocyst
    Authors: JJ Zylicz, M Borensztei, FC Wong, Y Huang, C Lee, S Dietmann, MA Surani
    Elife, 2018;7(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  54. Generation of a human Juvenile myelomonocytic leukemia iPSC line, CHOPi001-A, with a mutation in CBL
    Authors: AL Gagne, JA Maguire, S Gandre-Bab, ST Chou, SK Tasian, ML Loh, MJ Weiss, P Gadue, DL French
    Stem Cell Res, 2018;31(0):157-160.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  55. Sox7 promotes high-grade glioma by increasing VEGFR2-mediated vascular abnormality
    Authors: IK Kim, K Kim, E Lee, DS Oh, CS Park, S Park, JM Yang, JH Kim, HS Kim, DT Shima, JH Kim, SH Hong, YH Cho, YH Kim, JB Park, GY Koh, YS Ju, HK Lee, S Lee, I Kim
    J. Exp. Med., 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: IHC-P
  56. Coordinated Control of mRNA and rRNA Processing Controls Embryonic Stem Cell Pluripotency and Differentiation
    Authors: NS Corsini, AM Peer, P Moeseneder, M Roiuk, TR Burkard, HC Theussl, I Moll, JA Knoblich
    Cell Stem Cell, 2018;22(4):543-558.e12.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  57. Mapping the Mouse Cell Atlas by Microwell-Seq
    Authors: X Han, R Wang, Y Zhou, L Fei, H Sun, S Lai, A Saadatpour, Z Zhou, H Chen, F Ye, D Huang, Y Xu, W Huang, M Jiang, X Jiang, J Mao, Y Chen, C Lu, J Xie, Q Fang, Y Wang, R Yue, T Li, H Huang, SH Orkin, GC Yuan, M Chen, G Guo
    Cell, 2018;172(5):1091-1107.e17.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  58. Generation of nine induced pluripotent stem cell lines as an ethnic diversity panel
    Authors: X Gao, JJ Yourick, RL Sprando
    Stem Cell Res, 2018;31(0):193-196.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  59. Generation of Spinocerebellar Ataxia Type 2 induced pluripotent stem cell lines, CHOPi002-A and CHOPi003-A, from patients with abnormal CAG repeats in the coding region of the ATXN2 gene
    Authors: JA Maguire, AL Gagne, P Gonzalez-A, BL Davidson, V Shakkottai, P Gadue, DL French
    Stem Cell Res, 2018;34(0):101361.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  60. Derivation of induced pluripotent stem cells in Japanese macaque (Macaca fuscata)
    Authors: R Nakai, M Ohnuki, K Kuroki, H Ito, H Hirai, R Kitajima, T Fujimoto, M Nakagawa, W Enard, M Imamura
    Sci Rep, 2018;8(1):12187.
    Species: Primate - Macaca mulatta (Rhesus Macaque)
    Sample Types: Whole Cells
    Applications: ICC
  61. Derivation and characterization of the NIH registry human stem cell line NYSCF100 line under defined feeder-free conditions
    Authors: A Sevilla, E Forero, M Zimmer, H Martinez, K Reggio, D Paull, D Egli, S Noggle
    Stem Cell Res, 2018;29(0):99-102.
    Species: Human
    Sample Types: Whole Cells
    Applications: IHC
  62. Generation of two induced pluripotent stem cells lines from Mucopolysaccharydosis IIIA patient: IMEDEAi004-A and IMEDEAi004-B
    Authors: S Vallejo, A Fleischer, JM Martín, A Sánchez, E Palomino, D Bachiller
    Stem Cell Res, 2018;32(0):110-114.
    Species: Human
    Sample Types:
  63. Generation of a PXR reporter human induced pluripotent stem cell line (PXR-mCherry hiPSC) using the CRISPR/Cas9 system
    Authors: H Kim, JW Kim, SJ Kim, YJ Choi, DS Kim, HJ Park
    Stem Cell Res, 2017;26(0):72-75.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  64. Guided self-organization and cortical plate formation in human brain organoids
    Authors: MA Lancaster, NS Corsini, S Wolfinger, EH Gustafson, AW Phillips, TR Burkard, T Otani, FJ Livesey, JA Knoblich
    Nat. Biotechnol., 2017;0(0):.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  65. An Activating STAT3 Mutation Causes Neonatal Diabetes through Premature Induction of Pancreatic Differentiation
    Authors: J Saarimäki-, D Balboa, MA Russell, J Saarikettu, M Kinnunen, S Keskitalo, A Malhi, C Valensisi, C Andrus, S Eurola, H Grym, J Ustinov, K Wartiovaar, RD Hawkins, O Silvennoin, M Varjosalo, NG Morgan, T Otonkoski
    Cell Rep, 2017;19(2):281-294.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  66. Functional Thyroid Follicular Cells Differentiation from Human-Induced Pluripotent Stem Cells in Suspension Culture
    Authors: A Arauchi, K Matsuura, T Shimizu, T Okano
    Front Endocrinol (Lausanne), 2017;8(0):103.
    Species: Human
    Sample Types: Embryoid Bodies
    Applications: Flow Cytometry
  67. Lymphoblast-derived integration-free ISRM-CON9 iPS cell line from a 75year old female
    Authors: S Martins, M Bohndorf, F Schröter, F Assar, W Wruck, K Sleegers, C Van Broeck, J Adjaye
    Stem Cell Res, 2017;26(0):76-79.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  68. Activation of the Aryl Hydrocarbon Receptor Interferes with Early Embryonic Development
    Authors: M Gialitakis, M Tolaini, Y Li, M Pardo, L Yu, A Toribio, JS Choudhary, K Niakan, V Papayannop, B Stockinger
    Stem Cell Reports, 2017;9(5):1377-1386.
    Species: Mouse
    Sample Types: Embryo
    Applications: IHC-Fr
  69. Plasticity of the inner cell mass in mouse blastocyst is restricted by the activity of FGF/MAPK pathway
    Authors: M Wigger, K Kisielewsk, K Filimonow, B Plusa, M Maleszewsk, A Suwi?ska
    Sci Rep, 2017;7(1):15136.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  70. Identification of a small molecule that facilitates the differentiation of human iPSCs/ESCs and mouse embryonic pancreatic explants into pancreatic endocrine cells
    Authors: Y Kondo, T Toyoda, R Ito, M Funato, Y Hosokawa, S Matsui, T Sudo, M Nakamura, C Okada, X Zhuang, A Watanabe, A Ohta, N Inagaki, K Osafune
    Diabetologia, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  71. Acellular Mouse Kidney ECM can be Used as a Three-Dimensional Substrate to Test the Differentiation Potential of Embryonic Stem Cell Derived Renal Progenitors
    Authors: M Sambi, T Chow, J Whiteley, M Li, S Chua, V Raileanu, IM Rogers
    Stem Cell Rev, 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  72. TALEN-mediated shift of mitochondrial DNA heteroplasmy in MELAS-iPSCs with m.13513G>A mutation
    Authors: N Yahata, Y Matsumoto, M Omi, N Yamamoto, R Hata
    Sci Rep, 2017;7(1):15557.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  73. Insulin-producing cells derived from 'induced pluripotent stem cells' of patients with fulminant type 1 diabetes: vulnerability to cytokine insults and increased expression of apoptosis-related genes
    Authors: Y Hosokawa, T Toyoda, K Fukui, MY Baden, M Funato, Y Kondo, T Sudo, H Iwahashi, M Kishida, C Okada, A Watanabe, I Asaka, K Osafune, A Imagawa, I Shimomura
    J Diabetes Investig, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  74. Peripheral blood derived induced pluripotent stem cells (iPSCs) from a female with familial hypertrophic cardiomyopathy
    Authors: SB Ross, ST Fraser, RD Bagnall, C Semsarian
    Stem Cell Res, 2017;20(0):76-79.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  75. Dynamics of 5-carboxylcytosine during hepatic differentiation: potential general role for active demethylation by DNA repair in lineage specification
    Authors: LC Lewis, PC Lo, JM Foster, N Dai, IR Corrêa, PM Durczak, G Duncan, A Ramsawhook, GP Aithal, C Denning, NR Hannan, A Ruzov
    Epigenetics, 2017;0(0):0.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  76. The circular RNA circBIRC6 participates in the molecular circuitry controlling human pluripotency
    Authors: CY Yu, TC Li, YY Wu, CH Yeh, W Chiang, CY Chuang, HC Kuo
    Nat Commun, 2017;8(1):1149.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  77. Principles of early human development and germ cell program from conserved model systems
    Authors: T Kobayashi, H Zhang, WWC Tang, N Irie, S Withey, D Klisch, A Sybirna, S Dietmann, DA Contreras, R Webb, C Allegrucci, R Alberio, MA Surani
    Nature, 2017;546(7658):416-420.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  78. Generation of induced pluripotent stem cells (iPSCs) from a hypertrophic cardiomyopathy patient with the pathogenic variant p.Val698Ala in beta-myosin heavy chain (MYH7) gene
    Authors: SB Ross, ST Fraser, N Nowak, C Semsarian
    Stem Cell Res, 2017;20(0):88-90.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  79. Lineage Establishment and Progression within the Inner Cell Mass of the Mouse Blastocyst Requires FGFR1 and FGFR2
    Authors: M Kang, V Garg, AK Hadjantona
    Dev. Cell, 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  80. Distinct Requirements for FGFR1 and FGFR2 in Primitive Endoderm Development and Exit from Pluripotency
    Authors: A Molotkov, P Mazot, JR Brewer, RM Cinalli, P Soriano
    Dev. Cell, 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  81. Xist-dependent imprinted X inactivation and the early developmental consequences of its failure
    Authors: M Borensztei, L Syx, K Ancelin, P Diabangoua, C Picard, T Liu, JB Liang, I Vassilev, R Galupa, N Servant, E Barillot, A Surani, CJ Chen, E Heard
    Nat. Struct. Mol. Biol, 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  82. Accreditation of Biosafe Clinical-Grade Human Embryonic Stem Cells According to Chinese Regulations
    Authors: Q Gu, J Wang, L Wang, ZX Liu, WW Zhu, YQ Tan, WF Han, J Wu, CJ Feng, JH Fang, L Liu, L Wang, W Li, XY Zhao, BY Hu, J Hao, Q Zhou
    Stem Cell Reports, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  83. Human iPSC-Derived Neural Progenitors Are an Effective Drug Discovery Model for Neurological mtDNA Disorders
    Authors: C Lorenz, P Lesimple, R Bukowiecki, A Zink, G Inak, B Mlody, M Singh, M Semtner, N Mah, K Aur‚, M Leong, O Zabiegalov, EM Lyras, V Pfiffer, B Fauler, J Eichhorst, B Wiesner, N Huebner, J Priller, T Mielke, D Meierhofer, Z Izsv k, JC Meier, F Bouillaud, J Adjaye, M Schuelke, EE Wanker, A LombŠs, A Prigione
    Cell Stem Cell, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  84. Rapid DNA replication origin licensing protects stem cell pluripotency
    Authors: JP Matson, R Dumitru, P Coryell, RM Baxley, W Chen, K Twaroski, BR Webber, J Tolar, AK Bielinsky, JE Purvis, JG Cook
    Elife, 2017;6(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  85. Embryonic cholecystitis and defective gallbladder contraction in the Sox17-haploinsufficient model of biliary atresia
    Authors: H Higashiyam, A Ozawa, H Sumitomo, M Uemura, K Fujino, H Igarashi, K Imaimatsu, N Tsunekawa, Y Hirate, M Kurohmaru, Y Saijoh, M Kanai-Azum, Y Kanai
    Development, 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  86. Directed differentiation of human induced pluripotent stem cells into functional cholangiocyte-like cells
    Authors: F Sampazioti, MC de Brito, I Geti, A Bertero, NR Hannan, L Vallier
    Nat Protoc, 2017;12(4):814-827.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  87. Direct Reprogramming of Fibroblasts via a Chemically Induced XEN-like State
    Authors: X Li, D Liu, Y Ma, X Du, J Jing, L Wang, B Xie, D Sun, S Sun, X Jin, X Zhang, T Zhao, J Guan, Z Yi, W Lai, P Zheng, Z Huang, Y Chang, Z Chai, J Xu, H Deng
    Cell Stem Cell, 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  88. ICM conversion to epiblast by FGF/ERK inhibition is limited in time and requires transcription and protein degradation
    Authors: S Bessonnard, S Coqueran, S Vandormael, A Dufour, J Artus, M Cohen-Tann
    Sci Rep, 2017;7(1):12285.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  89. The chromatin modifier Satb1 regulates cell fate through Fgf signalling in the early mouse embryo
    Authors: M Goolam, M Zernicka-G
    Development, 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  90. Novel SOX17 frameshift mutations in endometrial cancer are functionally distinct from recurrent missense mutations
    Authors: CJ Walker, MJ O'Hern, VA Serna, T Kurita, MA Miranda, CE Sapp, DG Mutch, DE Cohn, PJ Goodfellow
    Oncotarget, 2017;8(40):68758-68768.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  91. p38 (Mapk14/11) occupies a regulatory node governing entry into primitive endoderm differentiation during preimplantation mouse embryo development
    Open Biol, 2016;6(9):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  92. Selection and dynamics of embryonic stem cell integration into early mouse embryos.
    Authors: Alexandrova S, Kalkan T, Humphreys P, Riddell A, Scognamiglio R, Trumpp A, Nichols J
    Development, 2016;143(1):24-34.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  93. Changes in Parthenogenetic Imprinting Patterns during Reprogramming by Cell Fusion
    Authors: Hyun Sik Jang
    PLoS ONE, 2016;11(5):e0156491.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: IHC
  94. The Anterior-Posterior Patterning of Definitive Endoderm Generated from Human Embryonic Stem Cells Depends on the Differential Signaling of Retinoic Acid, Wnt- and BMP-Signaling
    Authors: Claudia Davenport
    Stem Cells, 2016;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: IHC
  95. Diverse Functions of Retinoic Acid in Brain Vascular Development
    J Neurosci, 2016;36(29):7786-801.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  96. Ductular reaction-on-a-chip: Microfluidic co-cultures to study stem cell fate selection during liver injury
    Sci Rep, 2016;6(0):36077.
    Species: Rat
    Sample Types: Whole Cells
    Applications: IHC
  97. Hepatic differentiation of human pluripotent stem cells in miniaturized format suitable for high-throughput screen
    Authors: A Carpentier, I Nimgaonkar, V Chu, Y Xia, Z Hu, TJ Liang
    Stem Cell Res, 2016;16(3):640-650.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  98. Efficient derivation of extraembryonic endoderm stem cell lines from mouse postimplantation embryos
    Sci Rep, 2016;6(0):39457.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  99. Generation of optic atrophy 1 patient-derived induced pluripotent stem cells (iPS-OPA1-BEHR) for disease modeling of complex optic atrophy syndromes (Behr syndrome)
    Stem Cell Res, 2016;17(2):426-429.
    Species: Human
    Sample Types: Whole Cells
    Applications: IHC-Fr
  100. Inappropriate cadherin switching in the mouse epiblast compromises proper signaling between the epiblast and the extraembryonic ectoderm during gastrulation
    Sci Rep, 2016;6(0):26562.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: IHC
  101. Derivation of Patient Specific Pluripotent Stem Cells Using Clinically Discarded Cumulus Cells
    PLoS ONE, 2016;11(11):e0165715.
    Species: Human
    Sample Types: Whole Cells
    Applications: IHC-P
  102. Capturing the biology of disease severity in a PSC-based model of familial dysautonomia
    Authors: N Zeltner, F Fattahi, NC Dubois, N Saurat, F Lafaille, L Shang, B Zimmer, J Tchieu, MA Soliman, G Lee, JL Casanova, L Studer
    Nat. Med., 2016;22(12):1421-1427.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  103. Activin-A and Bmp4 levels modulate cell type specification during CHIR-induced cardiomyogenesis.
    Authors: Kim M, Horst A, Blinka S, Stamm K, Mahnke D, Schuman J, Gundry R, Tomita-Mitchell A, Lough J
    PLoS ONE, 2015;10(2):e0118670.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  104. Transcription activator-like effector nuclease (TALEN)-mediated CLYBL targeting enables enhanced transgene expression and one-step generation of dual reporter human induced pluripotent stem cell (iPSC) and neural stem cell (NSC) lines.
    Authors: Cerbini T, Funahashi R, Luo Y, Liu C, Park K, Rao M, Malik N, Zou J
    PLoS ONE, 2015;10(1):e0116032.
    Species: Human
    Sample Types: Whole Cells
    Applications: IHC
  105. Design of a Vitronectin-Based Recombinant Protein as a Defined Substrate for Differentiation of Human Pluripotent Stem Cells into Hepatocyte-Like Cells.
    Authors: Nagaoka M, Kobayashi M, Kawai C, Mallanna S, Duncan S
    PLoS ONE, 2015;10(8):e0136350.
    Species: Human
    Sample Types: Whole Cells
    Applications: IHC
  106. Automated, high-throughput derivation, characterization and differentiation of induced pluripotent stem cells.
    Authors: Paull D, Sevilla A, Zhou H, Hahn A, Kim H, Napolitano C, Tsankov A, Shang L, Krumholz K, Jagadeesan P, Woodard C, Sun B, Vilboux T, Zimmer M, Forero E, Moroziewicz D, Martinez H, Malicdan M, Weiss K, Vensand L, Dusenberry C, Polus H, Sy K, Kahler D, Gahl W, Solomon S, Chang S, Meissner A, Eggan K, Noggle S
    Nat Methods, 2015;12(9):885-92.
    Species: Human
    Sample Types: Whole Cells
    Applications: IHC
  107. Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis.
    Authors: Takasato M, Er P, Chiu H, Maier B, Baillie G, Ferguson C, Parton R, Wolvetang E, Roost M, Chuva de Sousa Lopes S, Little M
    Nature, 2015;526(7574):564-8.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  108. HEB associates with PRC2 and SMAD2/3 to regulate developmental fates.
    Authors: Yoon, Se-Jin, Foley, Joseph W, Baker, Julie C
    Nat Commun, 2015;6(0):6546.
    Species: Mouse
    Sample Types: Cell Lysates
    Applications: Western Blot
  109. Induction of pluripotency in human somatic cells via a transient state resembling primitive streak-like mesendoderm.
    Authors: Takahashi K, Tanabe K, Ohnuki M, Narita M, Sasaki A, Yamamoto M, Nakamura M, Sutou K, Osafune K, Yamanaka S
    Nat Commun, 2014;5(0):3678.
    Species: Human
    Sample Types: Whole Cells
    Applications: IHC
  110. Efficient programming of human eye conjunctiva-derived induced pluripotent stem (ECiPS) cells into definitive endoderm-like cells.
    Authors: Massumi M, Hoveizi E, Baktash P, Hooti A, Ghazizadeh L, Nadri S, Pourasgari F, Hajarizadeh A, Soleimani M, Nabiuni M, Khorramizadeh M
    Exp Cell Res, 2014;322(1):51-61.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  111. Generation and characterization of induced pluripotent stem cells from Aid-deficient mice.
    Authors: Shimamoto R, Amano N, Ichisaka T, Watanabe A, Yamanaka S, Okita K
    PLoS ONE, 2014;9(4):e94735.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  112. A modified EpiSC culture condition containing a GSK3 inhibitor can support germline-competent pluripotency in mice.
    Authors: Tsukiyama, Tomoyuki, Ohinata, Yasuhide
    PLoS ONE, 2014;9(4):e95329.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  113. Discovery of directional and nondirectional pioneer transcription factors by modeling DNase profile magnitude and shape.
    Authors: Sherwood, Richard, Hashimoto, Tatsunor, O'Donnell, Charles, Lewis, Sophia, Barkal, Amira A, van Hoff, John Pet, Karun, Vivek, Jaakkola, Tommi, Gifford, David K
    Nat Biotechnol, 2014;32(2):171-8.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  114. Citrullination regulates pluripotency and histone H1 binding to chromatin.
    Authors: Christophorou M, Castelo-Branco G, Halley-Stott R, Oliveira C, Loos R, Radzisheuskaya A, Mowen K, Bertone P, Silva J, Zernicka-Goetz M, Nielsen M, Gurdon J, Kouzarides T
    Nature, 2014;507(7490):104-8.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  115. Unfolded protein response is required for the definitive endodermal specification of mouse embryonic stem cells via Smad2 and beta-catenin signaling.
    Authors: Xu H, Tsang K, Wang Y, Chan J, Xu G, Gao W
    J Biol Chem, 2014;289(38):26290-301.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: IHC
  116. BMP signalling regulates the pre-implantation development of extra-embryonic cell lineages in the mouse embryo.
    Authors: Graham, Sarah J, Wicher, Krzyszto, Jedrusik, Agnieszk, Guo, Guoji, Herath, Wishva, Robson, Paul, Zernicka-Goetz, Magdalen
    Nat Commun, 2014;5(0):5667.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  117. Sox17-mediated maintenance of fetal intra-aortic hematopoietic cell clusters.
    Authors: Nobuhisa I, Osawa M, Uemura M, Kishikawa Y, Anani M, Harada K, Takagi H, Saito K, Kanai-Azuma M, Kanai Y, Iwama A, Taga T
    Mol Cell Biol, 2014;34(11):1976-90.
    Species: Mouse
    Sample Types: Embryo
    Applications: IHC
  118. GATA6 levels modulate primitive endoderm cell fate choice and timing in the mouse blastocyst.
    Authors: Schrode N, Saiz N, Di Talia S, Hadjantonakis A
    Dev Cell, 2014;29(4):454-67.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  119. miR-373 is regulated by TGFbeta signaling and promotes mesendoderm differentiation in human Embryonic Stem Cells.
    Authors: Rosa A, Papaioannou M, Krzyspiak J, Brivanlou A
    Dev Biol, 2014;391(1):81-8.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  120. Generation of functional insulin-producing cells from mouse embryonic stem cells through 804G cell-derived extracellular matrix and protein transduction of transcription factors.
    Authors: Kaitsuka T, Noguchi H, Shiraki N, Kubo T, Wei F, Hakim F, Kume S, Tomizawa K
    Stem Cells Transl Med, 2014;3(1):114-27.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  121. High oxygen condition facilitates the differentiation of mouse and human pluripotent stem cells into pancreatic progenitors and insulin-producing cells.
    Authors: Hakim F, Kaitsuka T, Raeed J, Wei F, Shiraki N, Akagi T, Yokota T, Kume S, Tomizawa K
    J Biol Chem, 2014;289(14):9623-38.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  122. Derivation of transgene-free human induced pluripotent stem cells from human peripheral T cells in defined culture conditions.
    Authors: Kishino, Yoshikaz, Seki, Tomohisa, Fujita, Jun, Yuasa, Shinsuke, Tohyama, Shugo, Kunitomi, Akira, Tabei, Ryota, Nakajima, Kazuaki, Okada, Marina, Hirano, Akinori, Kanazawa, Hideaki, Fukuda, Keiichi
    PLoS ONE, 2014;9(5):e97397.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  123. Cell-cycle control of developmentally regulated transcription factors accounts for heterogeneity in human pluripotent cells.
    Authors: Singh A, Chappell J, Trost R, Lin L, Wang T, Tang J, Matlock B, Weller K, Wu H, Zhao S, Jin P, Dalton S
    Stem Cell Reports, 2013;1(6):532-44.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  124. Production of hepatocyte-like cells from human pluripotent stem cells.
    Authors: Hannan, Nicholas, Segeritz, Charis-P, Touboul, Thomas, Vallier, Ludovic
    Nat Protoc, 2013;8(2):430-7.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  125. Defined extracellular matrix components are necessary for definitive endoderm induction.
    Authors: Taylor-Weiner H, Schwarzbauer J, Engler A
    Stem Cells, 2013;31(10):2084-94.
    Species: Mouse
    Sample Types: Cell Lysates
    Applications: Western Blot
  126. Identification of transcription factors for lineage-specific ESC differentiation.
    Authors: Yamamizu K, Piao Y, Sharov A, Zsiros V, Yu H, Nakazawa K, Schlessinger D, Ko M
    Stem Cell Reports, 2013;1(6):545-59.
  127. Self-renewal of embryonic-stem-cell-derived progenitors by organ-matched mesenchyme.
    Authors: Sneddon, Julie B, Borowiak, Malgorza, Melton, Douglas
    Nature, 2012;491(7426):765-8.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  128. CD166(pos) subpopulation from differentiated human ES and iPS cells support repair of acute lung injury.
    Authors: Soh, Boon Sen, Zheng, Dahai, Li Yeo, Julie Su, Yang, Henry He, Ng, Shi Yan, Wong, Lan Hion, Zhang, Wencai, Li, Pin, Nichane, Massimo, Asmat, Atasha, Wong, Poo Sing, Wong, Peng Che, Su, Lin Lin, Mantalaris, Sakis A, Lu, Jia, Xian, Wa, McKeon, Frank, Chen, Jianzhu, Lim, Elaine H, Lim, Bing
    Mol Ther, 2012;20(12):2335-46.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  129. The endothelial cell line bEnd.3 maintains human pluripotent stem cells.
    Authors: Joubin, Katherin, Richardson, Amelia, Novoa, Natalia, Tu, Edmund, Tomishima, Mark J
    Stem Cells Dev, 2012;21(12):2312-21.
    Species: Human
    Sample Types: Whole Cells
  130. A molecular signature for purified definitive endoderm guides differentiation and isolation of endoderm from mouse and human embryonic stem cells.
    Authors: Wang P, McKnight K, Wong D, Rodriguez R, Sugiyama T, Gu X, Ghodasara A, Qu K, Chang H, Kim S
    Stem Cells Dev, 2012;21(12):2273-87.
    Species: Mouse
    Sample Types: Cell Lysates
    Applications: Western Blot
  131. A novel chemically directed route for the generation of definitive endoderm from human embryonic stem cells based on inhibition of GSK-3.
    Authors: Bone HK, Nelson AS, Goldring CE, Tosh D, Welham MJ
    J. Cell. Sci., 2011;124(0):1992-2000.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  132. Early in vitro differentiation of mouse definitive endoderm is not correlated with progressive maturation of nuclear DNA methylation patterns.
    Authors: Tajbakhsh J, Gertych A, Fagg WS
    PLoS ONE, 2011;6(7):e21861.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  133. CD24: a novel surface marker for PDX1-positive pancreatic progenitors derived from human embryonic stem cells.
    Authors: Jiang W, Sui X, Zhang D, Liu M, Ding M, Shi Y, Deng H
    Stem Cells, 2011;29(4):609-17.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  134. The ROCK inhibitor Y-27632 improves recovery of human embryonic stem cells after fluorescence-activated cell sorting with multiple cell surface markers.
    Authors: Emre N, Vidal JG, Elia J
    PLoS ONE, 2010;5(8):e12148.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  135. Origin and formation of the first two distinct cell types of the inner cell mass in the mouse embryo.
    Authors: Morris SA, Teo RT, Li H, Robson P, Glover DM, Zernicka-Goetz M
    Proc. Natl. Acad. Sci. U.S.A., 2010;107(14):6364-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  136. Induction of pluripotent stem cells from human third molar mesenchymal stromal cells.
    Authors: Oda Y, Yoshimura Y, Ohnishi H
    J. Biol. Chem., 2010;285(38):29270-8.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  137. SIP1 mediates cell-fate decisions between neuroectoderm and mesendoderm in human pluripotent stem cells.
    Authors: Chng Z, Teo A, Pedersen RA, Vallier L
    Cell Stem Cell, 2010;6(1):59-70.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  138. A role for PDGF signaling in expansion of the extra-embryonic endoderm lineage of the mouse blastocyst.
    Authors: Artus J, Panthier JJ, Hadjantonakis AK
    Development, 2010;137(20):3361-72.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  139. Alginate microcapsule for propagation and directed differentiation of hESCs to definitive endoderm.
    Authors: Chayosumrit M, Tuch B, Sidhu K
    Biomaterials, 2010;31(3):505-14.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  140. Feeder-free derivation of induced pluripotent stem cells from adult human adipose stem cells.
    Authors: Sun N, Panetta NJ, Gupta DM, Wilson KD, Lee A, Jia F, Hu S, Cherry AM, Robbins RC, Longaker MT, Wu JC
    Proc. Natl. Acad. Sci. U.S.A., 2009;106(37):15720-5.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  141. Small molecules efficiently direct endodermal differentiation of mouse and human embryonic stem cells.
    Authors: Borowiak M, Maehr R, Chen S, Chen AE, Tang W, Fox JL, Schreiber SL, Melton DA
    Cell Stem Cell, 2009;4(4):348-58.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  142. Vitronectin promotes oligodendrocyte differentiation during neurogenesis of human embryonic stem cells.
    Authors: Gil JE, Woo DH, Shim JH, Kim SE, You HJ, Park SH, Paek SH, Kim SK, Kim JH
    FEBS Lett., 2009;583(3):561-7.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  143. Highly efficient differentiation of human ES cells and iPS cells into mature pancreatic insulin-producing cells.
    Authors: Zhang D, Jiang W, Liu M, Sui X, Yin X, Chen S, Shi Y, Deng H
    Cell Res., 2009;19(4):429-38.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  144. A late requirement for Wnt and FGF signaling during activin-induced formation of foregut endoderm from mouse embryonic stem cells.
    Authors: Hansson M, Olesen DR, Peterslund JM, Engberg N, Kahn M, Winzi M, Klein T, Maddox-Hyttel P, Serup P
    Dev. Biol., 2009;330(2):286-304.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  145. Biphasic induction of Pdx1 in mouse and human embryonic stem cells can mimic development of pancreatic beta-cells.
    Authors: Bernardo AS, Cho CH, Mason S, Docherty HM, Pedersen RA, Vallier L, Docherty K
    Stem Cells, 2009;27(2):341-51.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  146. High-throughput screening assay for the identification of compounds regulating self-renewal and differentiation in human embryonic stem cells.
    Authors: Desbordes SC, Placantonakis DG, Ciro A, Socci ND, Lee G, Djaballah H, Studer L
    Cell Stem Cell, 2008;2(6):602-12.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  147. Prospective isolation and global gene expression analysis of definitive and visceral endoderm.
    Authors: Sherwood RI, Jitianu C, Cleaver O, Shaywitz DA, Lamenzo JO, Chen AE, Golub TR, Melton DA
    Dev. Biol., 2007;304(2):541-55.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  148. Long-term self-renewal and directed differentiation of human embryonic stem cells in chemically defined conditions.
    Authors: Yao S, Chen S, Clark J, Hao E, Beattie GM, Hayek A, Ding S
    Proc. Natl. Acad. Sci. U.S.A., 2006;103(18):6907-12.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  149. Generation of a human Ocular Albinism type 1 iPSC line, SEIi001-A, with a mutation in GPR143.
    Authors: Baulier E, Garcia Diaz A, Corneo B, Farber D
    Stem Cell Res, 0;33(0):274-277.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay

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Reviews for Human SOX17 Antibody

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Human SOX17 Antibody
By Anonymous on 04/15/2019
Application: ICC/IF Sample Tested: Differentiated embryonic stem cells Species: Human

SOX17 antibody was used to assess the efficient differentiation of hESCs towards Definitive endoderm
cells were fixed by adding 4%PFA for 15min
blocking buffer contained 10%FCS, 0.1% BSA in PBS
For permeabilisation 0.5% Triton X-100 was used
Antibody was used at 10mg/ml and left o/n at 4oC

Immunocytochemistry/Immunofluorescence Human SOX17 Antibody AF1924
Human SOX17 Antibody
By Anonymous on 04/13/2018
Application: WB Sample Tested: Tumor cell lyastes Species: Human
Human SOX17 Antibody
By Anonymous on 12/15/2016
Application: ICC/IF Sample Tested: Induced Pluripotent Stem Cells,Endoderm Species: Human

Used this antibody to verify the endodermal germ layer derived from iPSC.