Human TGF-beta RII Antibody
Human TGF-beta RII Antibody Summary
Thr23-Asp184
Accession # NP_001020018
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Applications
This antibody functions as an ELISA detection antibody when paired with Mouse Anti-Human TGF‑ beta RII Monoclonal Antibody (Catalog # MAB2411).
This product is intended for assay development on various assay platforms requiring antibody pairs. We recommend the Human TGF-beta RII DuoSet ELISA Kit (Catalog # DY241) for convenient development of a sandwich ELISA.
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
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Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: TGF-beta RII
TGF-beta RII is a membrane-bound serine/threonine kinase. Upon ligand binding, TGF-beta RII interacts with TGF-beta RI to form the heteromeric signaling complex that transduces TGF-beta signals. A splice variant of the type II receptor, TGF-beta RIIb, containing a 25 amino acid residue insertion near the N-terminus of the mature protein has also been described.
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