Human TGF‑ beta RII Antibody

Name: Human TGF‑ beta RII Antibody
Brand: R&D Systems
SKU: MAB2412
Price: 369 USD
Availability: InStock

R&D Systems | Catalog # MAB2412

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Product Specifications
Applications
Preparation & Storage
Calculators
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species Reactivity

Human

Applications

ELISA

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG_2A Clone # 176507

View all TGF-beta RII Primary Antibodies »

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant human TGF‑ beta RII
Thr23-Asp184
Accession # NP_001020018

Specificity

Detects human TGF-beta RII in sandwich ELISAs.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG_2A

Applications for Human TGF‑ beta RII Antibody

Application

Recommended Usage

ELISA

This antibody functions as an ELISA detection antibody when paired with Mouse Anti-Human TGF‑ beta RII Monoclonal Antibody (Catalog # MAB2411).

This product is intended for assay development on various assay platforms requiring antibody pairs. We recommend the Human TGF-beta RII DuoSet ELISA Kit (Catalog # DY241) for convenient development of a sandwich ELISA.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

Background: TGF-beta RII

TGF-beta RII is a membrane-bound serine/threonine kinase. Upon ligand binding, TGF-beta RII interacts with TGF-beta RI to form the heteromeric signaling complex that transduces TGF-beta signals. A splice variant of the type II receptor, TGF-beta RIIb, containing a 25 amino acid residue insertion near the N-terminus of the mature protein has also been described.