Mouse MOG Antibody

Catalog # Availability Size / Price Qty
AF2439
AF2439-SP
MOG in Mouse Brain.
1 Image
Product Details
Citations (4)
FAQs
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Mouse MOG Antibody Summary

Species Reactivity
Mouse
Specificity
Detects mouse MOG in direct ELISAs and Western blots. In direct ELISAs, less than 40% cross-reactivity with recombinant human MOG is observed.
Source
Polyclonal Goat IgG
Purification
Antigen Affinity-purified
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse MOG
Gly29-Gly153
Accession # Q61885
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
Label
Unconjugated

Applications

Recommended Concentration
Sample
Western Blot
0.1 µg/mL
Recombinant Mouse MOG
Immunohistochemistry
5-15 µg/mL
See below

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Data Example

Immunohistochemistry MOG in Mouse Brain. View Larger

MOG in Mouse Brain. MOG was detected in perfusion fixed frozen sections of mouse brain (cortex) using 15 µg/mL Goat Anti-Mouse MOG Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2439) overnight at 4 °C. Tissue was stained with the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS008) and counterstained with hematoxylin (blue). View our protocol for Chromogenic IHC Staining of Frozen Tissue Sections.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Reconstitution
Reconstitute at 0.2 mg/mL in sterile PBS.
Reconstitution Buffer Available
Reconstitution Buffer 1 (PBS)
Catalog #
Availability
Size / Price
Qty
RB01
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: MOG

Mouse MOG is an integral membrane protein belonging to the immunoglobulin superfamily. It is found exclusively on myelinating oligodendrocytes in the central nervous system. The amino-terminal extracellular domain of mouse MOG shares 97% and 92% amino acid sequence identity with the corresponding regions of rat and human MOG, respectively.

Long Name
Myelin Oligodendrocyte Glycoprotein
Entrez Gene IDs
4340 (Human); 17441 (Mouse)
Alternate Names
MGC26137; MOG Ig-AluB; MOG; MOGIG2; myelin oligodendrocyte glycoprotein; myelin-oligodendrocyte glycoprotein

Product Datasheets

Citations for Mouse MOG Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

4 Citations: Showing 1 - 4
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  1. Ninjurin1 deficiency attenuates susceptibility of experimental autoimmune encephalomyelitis in mice.
    Authors: Ahn, Bum Ju, Le, Hoang, Shin, Min Wook, Bae, Sung-Jin, Lee, Eun Ji, Wee, Hee-Jun, Cha, Jong-Ho, Lee, Hyo-Jong, Lee, Hye Shin, Kim, Jeong Hu, Kim, Chang-Ye, Seo, Ji Hae, Lo, Eng H, Jeon, Sejin, Lee, Mi-Ni, Oh, Goo Taeg, Yin, Guo Nan, Ryu, Ji-Kan, Suh, Jun-Kyu, Kim, Kyu-Won
    J Biol Chem, 2014;289(6):3328-38.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  2. Contactin-1 regulates myelination and nodal/paranodal domain organization in the central nervous system.
    Authors: Colakoglu G, Bergstrom-Tyrberg U, Berglund E, Ranscht B
    Proc Natl Acad Sci U S A, 2014;111(3):E394-403.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  3. In vivo imaging of dorsal root regeneration: rapid immobilization and presynaptic differentiation at the CNS/PNS border.
    Authors: Di Maio A, Skuba A, Himes BT
    J. Neurosci., 2011;31(12):4569-82.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  4. Negative regulation of autoimmune demyelination by the inhibitory receptor CLM-1.
    Authors: Xi H, Katschke KJ, Helmy KY, Wark PA, Kljavin N, Clark H, Eastham-Anderson J, Shek T, Roose-Girma M, Ghilardi N, van Lookeren Campagne M
    J. Exp. Med., 2010;207(1):7-16, S1-5.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC Fresh

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Cell and Tissue Staining Kits

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Secondary Antibodies

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