757 results for "CD117/c-kit" in Products
CD117/c-kit Products
CD117, also known as c-kit and SCF R, is the cellular receptor for Stem Cell Factor (SCF), also named c-kit ligand, mast cell growth factor, and steel factor. This receptor-ligand system plays essential roles in germ cell development, melanogenesis, hematopoiesis, and oncogenesis. CD117 is expressed on lymphoid, myeloid, erythroid, and megakaryocyte progenitors, NK cells, germ cells, melanocytes, glial cells, vascular smooth muscle cells, placenta, and epithelial cells. Altered levels and mutations in CD117 are associated with several types of cancer including lung, breast, gastrointestinal stromal, and germ cell tumors.
| Reactivity: | Human |
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| Reactivity: | Human, Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | IHC, WB, Flow, Dual ISH-IHC, Simple Western, + 1 More |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | IHC, WB, B/N, Flow, Simple Western, + 1 More |
Contains 4 membranes - each spotted in duplicate with 49 different RTK antibodies
| Reactivity: | Human |
| Reactivity: | Human, Mouse |
| Details: | Rat IgG2b Kappa Monoclonal Clone #2B8 |
| Applications: | IHC, Flow, ICC/IF, IP |
![Flow Cytometry: CD117/c-kit Antibody (2B8) - BSA Free [NB100-77477]](https://resources.rndsystems.com/images/products/CD117-c-kit-Antibody-2B8-Flow-Cytometry-NB100-77477-img0003.jpg "Flow Cytometry: CD117/c-kit Antibody (2B8) - BSA Free [NB100-77477]")
| Reactivity: | Human, Mouse, Guinea Pig |
| Details: | Rat IgG2b Kappa Monoclonal Clone #ACK2 |
| Applications: | IHC, WB, Flow, ICC/IF, IP |
![Immunohistochemistry Whole-Mount: CD117/c-kit Antibody (ACK2) - BSA Free [NBP1-43359]](https://resources.rndsystems.com/images/products/CD117-c-kit-Antibody-ACK2-Immunohistochemistry-Whole-Mount-NBP1-43359-img0003.jpg "Immunohistochemistry Whole-Mount: CD117/c-kit Antibody (ACK2) - BSA Free [NBP1-43359]")
| Reactivity: | Mouse |
| Details: | Rat IgG2A Monoclonal Clone #180627 |
| Applications: | IHC, WB, Flow, CyTOF-ready |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #47233 |
| Applications: | WB, ELISA(Cap), B/N, Flow, Simple Western, + 1 More |
| Reactivity: | Human |
| Source: | Sf 21 (baculovirus) |
| Accession #: | P10721 |
| Applications: | Bioactivity |
VEGFR inhibitor. Also inhibits KIT, RET, MET and FLT3
| Alternate Names: | Semaxinib |
| Chemical Name: | 3-[(3,5-Dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-2H-indol-2-one |
| Purity: | ≥98% |
| Reactivity: | Human, Mouse |
| Details: | Rat IgG2b Kappa Monoclonal Clone #2B8 |
| Applications: | IHC, Flow, ICC/IF, IP, CyTOF-ready |
![Flow Cytometry: CD117/c-kit Antibody (2B8) - Azide and BSA Free [NBP2-80624]](https://resources.rndsystems.com/images/products/CD117-c-kit-Antibody-2B8-Azide-and-BSA-Free-Flow-Cytometry-NBP2-80624-img0002.jpg "Flow Cytometry: CD117/c-kit Antibody (2B8) - Azide and BSA Free [NBP2-80624]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, Simple Western |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, Simple Western |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #CL1657 |
| Applications: | IHC, WB |
![Western Blot: CD117/c-kit Antibody (CL1657) [NBP2-52975]](https://resources.rndsystems.com/images/products/CD117-c-kit-Antibody-CL1657-Western-Blot-NBP2-52975-img0006.jpg "Western Blot: CD117/c-kit Antibody (CL1657) [NBP2-52975]")
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #OTI2B12 |
| Applications: | IHC, WB |
![Western Blot: CD117/c-kit Antibody (OTI2B12) [NBP2-45508]](https://resources.rndsystems.com/images/products/CD117-c-kit-Antibody-2B12-Western-Blot-NBP2-45508-img0013.jpg "Western Blot: CD117/c-kit Antibody (OTI2B12) [NBP2-45508]")
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #OTI2B12 |
| Applications: | IHC, WB |
![Western Blot: CD117/c-kit Antibody (OTI2B12)Azide and BSA Free [NBP2-71076]](https://resources.rndsystems.com/images/products/CD117-c-kit-Antibody-OTI2B12-Azide-and-BSA-Free-Western-Blot-NBP2-71076-img0001.jpg "Western Blot: CD117/c-kit Antibody (OTI2B12)Azide and BSA Free [NBP2-71076]")
| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #CL1667 |
| Applications: | IHC, WB |
![Western Blot: CD117/c-kit Antibody (CL1667) [NBP2-34487]](https://resources.rndsystems.com/images/products/CD117-c-kit-Antibody-CL1667-Western-Blot-NBP2-34487-img0006.jpg "Western Blot: CD117/c-kit Antibody (CL1667) [NBP2-34487]")
| Reactivity: | Human |
| Assay Range: | 31.2-2000 pg/mL |
| Applications: | ELISA |
Potent and selective v-Abl tyrosine kinase inhibitor; also inhibits PDGFR and c-kit
| Alternate Names: | Gleevec,CGP 57148B |
| Chemical Name: | 4-[(4-Methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]benzamide methanesulfonate |
| Purity: | ≥98% |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC |
![Immunohistochemistry-Paraffin: CD117/c-kit Antibody [NBP1-85593]](https://resources.rndsystems.com/images/products/CD117-c-kit-Antibody-Immunohistochemistry-Paraffin-NBP1-85593-img0004.jpg "Immunohistochemistry-Paraffin: CD117/c-kit Antibody [NBP1-85593]")
| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #CL1667 |
| Applications: | IHC, WB |
![CD117/c-kit Antibody (CL1667) - Azide and BSA Free Western Blot: CD117/c-kit Antibody [NBP3-44073]](https://resources.rndsystems.com/images/products/nbp3-44073_mouse-cd117-c-kit-mab-cl1667-azide-and-bsa-free-282202512104214.jpg "Western Blot: CD117/c-kit Antibody [NBP3-44073]")
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #CL1657 |
| Applications: | IHC, WB |
![CD117/c-kit Antibody (CL1657) - Azide and BSA Free Immunohistochemistry-Paraffin: CD117/c-kit Antibody [NBP3-44075]](https://resources.rndsystems.com/images/products/nbp3-44075_mouse-cd117-c-kit-mab-cl1657-azide-and-bsa-free-282202512182743.jpg "Immunohistochemistry-Paraffin: CD117/c-kit Antibody [NBP3-44075]")
c-Fms inhibitor; suppresses osteolysis and osteoclast accumulation
| Chemical Name: | N-[4-[(6,7-Dimethoxy-4-quinolinyl)oxy]-2-methoxyphenyl]-N'-[1-(2-thiazolyl)ethyl]urea |
| Purity: | ≥97% |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | IHC, WB, Flow |
| Reactivity: | Human |
| Applications: | ELISA |
