191 results for "GABA-B R2" in Products
GABA-B R2 Products
The neurotransmitter gamma-aminobutyric acid (GABA) mediates an inhibitory signal upon binding to two ligand-gated channels, GABA-A and GABA-C receptors, and a G-protein linked receptor, GABA-B. The GABA-B receptor is a heterodimeric complex composed of two 7-transmembrane GPCRs termed GABA-B R1 and GABA-B R2. GABA-B receptors have been implicated in the GABA-induced modulation of sympathetic and catecholaminergic pathways in the central nervous system.
Potent and selective GABAB antagonist
| Chemical Name: | (2S)-3-[[(1S)-1-(3,4-Dichlorophenyl)ethyl]amino-2-hydroxypropyl](phenylmethyl)phosphinic acid hydrochloride |
| Purity: | ≥98% |
Recombinant Monoclonal Antibody.
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #2605C |
| Applications: | IHC, WB, Simple Western |
| Reactivity: | Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | IHC, WB, Simple Western |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #S81-2 |
| Applications: | IHC, WB, ICC/IF |
Selective GABAB agonist; active enantiomer of (RS)-Baclofen (Cat. No. 0417)
| Alternate Names: | STX 209 |
| Chemical Name: | (R)-4-Amino-3-(4-chlorophenyl)butanoic acid |
| Purity: | ≥99% |
Potent and selective GABAB antagonist
| Chemical Name: | [S-(R*,R*)]-[3-[[1-(3,4-Dichlorophenyl)ethyl]amino]-2-hydroxypropyl](cyclohexylmethyl) phosphinic acid |
| Purity: | ≥96% |
Selective GABAB antagonist
| Chemical Name: | (RS)-3-Amino-2-(4-chlorophenyl)propylsulfonic acid |
| Purity: | ≥98% |
Recombinant Monoclonal Antibody.
| Reactivity: | Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #2605F |
| Applications: | WB, Simple Western |
| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #5G7F7 |
| Applications: | IHC, WB, ELISA, ICC/IF |
Selective GABAB antagonist; more potent than Saclofen (Cat. No. 0246)
| Chemical Name: | (RS)-3-Amino-2-(4-chlorophenyl)-2-hydroxypropyl-sulfonic acid |
Selective and competitive GABAB antagonist; orally bioavailable
| Chemical Name: | (2S)-(+)-5,5-Dimethyl-2-morpholineacetic acid |
| Purity: | ≥98% |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC |
Selective GABAB antagonist; brain penetrant
| Chemical Name: | (3-Aminopropyl)(diethoxymethyl)phosphinic acid |
Potent and selective GABAB antagonist
| Chemical Name: | 3-[[(3,4-Dichlorophenyl)methyl]amino]propyl] diethoxymethyl)phosphinic acid |
| Purity: | ≥98% |
Caged GABA; inhibits neural activity
| Alternate Names: | RuBi-GABA-PMe3 |
| Chemical Name: | (bis(2,2'-Bipyridine-N,N')trimethylphosphine)-4-aminobutyric acid ruthenium complex sodium hexafluorophosphate salt |
| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #5G7B9 |
| Applications: | IHC, WB, ELISA |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC |
Highly potent GABAB agonist; also GABAA-ρ antagonist
| Alternate Names: | CGP 35024 |
| Chemical Name: | 3-Aminopropyl(methyl)phosphinic acid |
Selective GABAB agonist
| Chemical Name: | (RS)-4-Amino-3-(4-chlorophenyl)butanoic acid |
| Purity: | ≥99% |
Positive allosteric modulator of GABAB receptors
| Chemical Name: | 3,5-bis(1,1-Dimethylethyl)-4-hydroxy-β,β-dimethyl-benzenepropanol |
| Purity: | ≥98% |
Positive allosteric modulator of GABAB receptors
| Chemical Name: | N,N'-Dicyclopentyl-2-(methylthio)-5-nitro-4,6-pyrimidinediamine |
| Purity: | ≥98% |
GABAB antagonist; displays activity at presynaptic receptors
| Chemical Name: | (3-Aminopropyl)ethylphosphinic acid hydrochloride |
| Purity: | ≥98% |
Potent and selective postitive allosteric modulator of GABAB receptors
| Chemical Name: | 5,7-Bis(1,1-dimethylethyl)-3-hydroxy-3(trifluoromethyl)-2(3H)-benzofuranone |
| Purity: | ≥98% |
| Reactivity: | Human |
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #SR1039 |
| Applications: | IHC, WB, Flow, ICC/IF |