349 results for "TrkA" in Products

TrkA Products

TrkA, the product of the protooncogene trk, is a member of the neurotrophic tyrosine kinase receptor family that has three members. TrkA, TrkB and TrkC preferentially bind NGF, NT-4 and BDNF, and NT-3, respectively. All Trk family proteins share a conserved complex subdomain organization consisting of a signal peptide, two cysteine-rich domains, a cluster of three leucine-rich motifs, and two immunoglobulin-like domains in the extracellular region, as well as an intracellular region that ...

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Contains 4 membranes - each spotted in duplicate with 49 different RTK antibodies

Reactivity: Human
Detection of Human Receptor Tyrosine Kinase Phosphorylation in KATO-III Cell Line.
(2)
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Reactivity: Human
Source: NS0
Accession #: AAA36770
Applications: Bioactivity
R&D Systems Recombinant Proteins and Enzymes
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Recombinant Monoclonal Antibody

Reactivity: Human, Mouse, Rat
Details: Rabbit IgG Monoclonal Clone #JJ084-04
Applications: IHC, WB, Flow, ICC/IF, IP
Western Blot: TrkA Antibody (JJ084-04) [NBP2-67473]
(10)
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Recombinant Monoclonal Antibody.

Reactivity: Human
Details: Mouse IgG1 Monoclonal Clone #165131R
Applications: KO, Flow, CyTOF-ready
Detection of TrkA antibody in BAF Cell Line Transfected with Human TrkA and eGFP antibody by Flow Cytometry.
(5)
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Reactivity: Human
Details: Mouse IgG1 Monoclonal Clone #994307
Applications: B/N, Flow, ICC/IF, CyTOF-ready
Detection of TrkA antibody in HEK293 Human Cell Line Transfected with Human TrkA and eGFP antibody by Flow Cytometry.
(3)
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JAK2, FLT3 and TrkA inhibitor; also inhibits AurA and AurB

Alternate Names: CEP-701
Chemical Name: (9S,10S,12R)-2,3,9,10,11,12-Hexahydro-10-hydroxy-10-(hydroxymethyl)-9-methyl-9,12-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocin-1-one
Purity: ≥98%
JAK2, FLT3 and TrkA inhibitor; also inhibits AurA and AurB
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Analyzed by SEC-MALS

Reactivity: Cynomolgus Monkey, Rhesus Macaque
Source: CHO
Accession #: XP_005541454.3
Applications: Bioactivity
(3)
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Reactivity: Rat
Source: NS0
Accession #: P35739
Applications: Bioactivity
R&D Systems Recombinant Proteins and Enzymes
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Reactivity: Human
Source: HEK293
Accession #: P04629-1
Applications: Bioactivity
Recombinant Human TrkA His Tagged Protein Bioactivity
(2)
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Reactivity: Human
Details: Rabbit IgG Polyclonal
Applications: IHC
Immunohistochemistry-Paraffin: TrkA Antibody [NBP2-38265]
(6)
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Potent, selective TrkA inhibitor

Chemical Name: 1,3-Dihydro-3-[(1-methyl-1H-indol-3-yl)methylene]-2H-pyrrolo[3,2-b]pyridin-2-one
Purity: ≥99%
Potent, selective TrkA inhibitor
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Reactivity: Cynomolgus Monkey, Rhesus Macaque
Source: CHO
Accession #: XP_005541454.3
Applications: Bioactivity
(2)
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Reactivity: Mouse
Source: NS0
Accession #: Q3UFB7
Applications: Bioactivity
Recombinant Mouse TrkA Fc Chimera Protein Bioactivity
(2)
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Inhibits NGF binding to p75NTR and TrkA

Chemical Name: 2,3,4,10-Tetrahydro-7,10-dimethyl-2,4-dioxobenzo[g]pteridine-8-carboxaldehyde
Purity: ≥95%
Inhibits NGF binding to p75NTR and TrkA
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Potent Trk inhibitor; inhibits TrkA, TrkB and TrkC

Chemical Name: N-[3-[[2,3-Dihydro-2-oxo-3-(1H-pyrrol-2-ylmethylene)-1H-indol-6-yl]amino]-4-methylphenyl]-N'-[2-fluoro-5-(trifluoromethyl)phenyl]urea
Purity: ≥98%
Potent Trk inhibitor; inhibits TrkA, TrkB and TrkC
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Potent and selective pan-Trk inhibitor; peripherally restricted

Chemical Name: N-[5-[[2-Amino-7-(2-hydroxy-1,1-dimethylethyl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]carbonyl]-3-pyridinyl]-5-chloro-2-pyridineacetamide
Purity: ≥98%
Potent and selective pan-Trk inhibitor; peripherally restricted
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Reactivity: Human, Mouse, Rat
Details: Mouse IgG1 Monoclonal Clone #OTI5B6
Applications: IHC, WB
Western Blot: TrkA Antibody (OTI5B6) [NBP2-46266]
(2)
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Recombinant Monoclonal Antibody

Reactivity: Human
Details: Mouse IgG1 Monoclonal Clone #165131R
Applications: KO, Flow
Detection of TrkA antibody in BAF Cell Line Transfected with Human TrkA and eGFP antibody by Flow Cytometry.
(3)
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Recombinant Monoclonal Antibody

Reactivity: Human
Details: Mouse IgG1 Monoclonal Clone #165131R
Applications: KO, Flow
Detection of TrkA antibody in BAF Cell Line Transfected with Human TrkA and eGFP antibody by Flow Cytometry.
(3)
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