Human CRHR-1 Antibody

Catalog # Availability Size / Price Qty
MAB3930
MAB3930-SP
Product Details
Citations (1)
FAQs
Supplemental Products
Reviews

Human CRHR-1 Antibody Summary

Species Reactivity
Human
Specificity
Detects human CRHR‑1 transfectants but not irrelevant transfectants.
Source
Monoclonal Mouse IgG2A Clone # 343919
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
NS0 mouse myeloma cell line transfected with human CRHR-1
Ser24-Val415
Accession # NP_004373
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Applications

Recommended Concentration
Sample
Flow Cytometry
2.5 µg/106 cells
Human CRHR‑1 transfected Ba/F3 cells
Immunohistochemistry
8-25 µg/mL
Immersion fixed paraffin-embedded sections of human placenta
CyTOF-ready
Ready to be labeled using established conjugation methods. No BSA or other carrier proteins that could interfere with conjugation.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Preparation and Storage

Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS.
Reconstitution Buffer Available
Reconstitution Buffer 1 (PBS)
Catalog #
Availability
Size / Price
Qty
RB01
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: CRHR1

Corticotrophin-Releasing Hormone Receptor 1 (CRHR-1), also known as CRFR-1, is a 7TM protein that belongs to the G protein-coupled receptor family 2. CRHR-1 is expressed in the brain and adrenal gland where it mediates corticotropin-induced effects on anxiety, depression, and stress-associated pathologies. The immunogen for this antibody corresponds to one of the four alternately spliced forms and has a 29 amino acid deletion in the first cytoplasmic domain. Human CRHR-1 shares 97% amino acid sequence identity with mouse and rat CRHR-1.

Long Name
Corticotropin Releasing Hormone Receptor 1
Entrez Gene IDs
1394 (Human); 12921 (Mouse)
Alternate Names
CHR-R1; corticotropin releasing hormone receptor 1; corticotropin-releasing factor receptor 1; corticotropin-releasing factor type 1 receptor; Corticotropin-releasing hormone receptor 1; CRF1; CRFR; CRF-R; CRFR1; CRF-R1; CRF-R-1; CRFR-1; CRHR1; CRH-R-1; CRHR1f; CRH-R1h; CRHR1L; CRHRCRH-R1; seven transmembrane helix receptor

Product Datasheets

Citation for Human CRHR-1 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

1 Citation: Showing 1 - 1

  1. Conformation-specific monoclonal antibodies recognizing the native structure of G protein-coupled receptor (GPCR)
    Authors: Y Isozaki, K Tsumoto, M Tomita
    International immunopharmacology, 2021;98(0):107872.
    Species: Chinese Hamster
    Sample Types: Whole Cells
    Applications: IHC

FAQs

No product specific FAQs exist for this product, however you may

View all Antibody FAQs

Isotype Controls

Mouse IgG2A Isotype Control

Reconstitution Buffers

Secondary Antibodies

Reviews for Human CRHR-1 Antibody

There are currently no reviews for this product. Be the first to review Human CRHR-1 Antibody and earn rewards!

Have you used Human CRHR-1 Antibody?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review