Human LXR alpha/NR1H3 Ligand Binding Domain Antibody

R&D Systems | Catalog # PP-PPZ0412-00

R&D Systems
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human, Mouse, Transgenic Mouse

Applications

Validated:

Immunohistochemistry, Western Blot, Immunoprecipitation, Gel Supershift Assay

Cited:

Immunohistochemistry-Paraffin, Western Blot, Chromatin Immunoprecipitation (ChIP)

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2A Clone # PPZ0412
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Product Specifications

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Applications for Human LXR alpha/NR1H3 Ligand Binding Domain Antibody

Application
Recommended Usage

Gel Supershift Assay

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Formulation

A liquid formulation in physiologic saline with 0.1% NaN3.

Shipping

The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store the unopened product at -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: LXR alpha/NR1H3

Liver X Receptors (LXRs) are oxysterol activated nuclear receptors which are involved in the regulation of cholesterol metabolism and bile acids. Two known isoforms, alpha and beta, are differentially expressed. The alpha isoform is predominantly expressed in liver, whereas the beta isoform expression has been shown to be ubiquitous.

LXR antibodies are useful for lipid and cholesterol metabolism studies.

Long Name

Liver X Receptor alpha

Alternate Names

NR1H3, RLD-1

Entrez Gene IDs

10062 (Human)

Gene Symbol

NR1H3

Additional LXR alpha/NR1H3 Products

Product Documents for Human LXR alpha/NR1H3 Ligand Binding Domain Antibody

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Human LXR alpha/NR1H3 Ligand Binding Domain Antibody

For research use only

Citations for Human LXR alpha/NR1H3 Ligand Binding Domain Antibody

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Protocols

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