Human/Mouse/Rat PTP mu/PTPRM Antibody

Catalog # Availability Size / Price Qty
Detection of Human PTPμ/PTPRM by Western Blot.
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Product Details
Citations (1)
Supplemental Products

Human/Mouse/Rat PTP mu/PTPRM Antibody Summary

Species Reactivity
Human, Mouse, Rat
Detects human, mouse, and rat PTPμ/PTPRM in Western blots. In Western blots, no cross-reactivity with recombinant human PTPRK, PTPRT, PTPRD, PTPRG, PTPRF (LAR), or DEP1 is observed.
Monoclonal Mouse IgG2B Clone # 436502
Protein A or G purified from hybridoma culture supernatant
Mouse myeloma cell line NS0-derived recombinant human PTPμ/PTPRM
Accession # P28827
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.


Recommended Concentration
Western Blot
1 µg/mL
See below

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Western Blot Detection of Human PTPµ/PTPRM antibody by Western Blot. View Larger

Detection of Human PTPμ/PTPRM by Western Blot. Western blot shows lysates of HepG2 human hepatocellular carcinoma cell line, and CHP-100 human neuroblastoma cell line. PVDF membrane was probed with 1 µg/mL of Mouse Anti-Human/Mouse/Rat PTPµ/PTPRM Monoclonal Antibody (Catalog # MAB4446) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF007). A specific band was detected for PTPµ/PTPRM at approximately 280 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.


Preparation and Storage

Reconstitute at 0.5 mg/mL in sterile PBS.
Reconstitution Buffer Available
Reconstitution Buffer 1 (PBS)
Catalog #
Size / Price
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: PTP mu/PTPRM

Protein Tyrosine Phosphatase, receptor type M (PTPRM), also called PTPμ, PTPRμ, and RPTPμ, is expressed at highest levels in pulmonary vascular epithelia, where interactions with cadhedrins are believed to be important in regulating barrier permeability. The MAM and Fibronectin III (FNIII) domains on the extracellular side of PTPRM bind between cells, affecting adhesion and contact inhibition. Culturing cells to high density concentrates PTPRM at sites of tight contact and induces proteolytic cleavage of the 100 kDa extracellular domain.

Long Name
Protein Tyrosine Phosphatase Receptor-type M
Entrez Gene IDs
5797 (Human); 19274 (Mouse); 29616 (Rat)
Alternate Names
EC; hR-PTPu; MGC166994; protein tyrosine phosphatase mu; protein tyrosine phosphatase, receptor type, M; protein tyrosine phosphatase, receptor type, mu polypeptide; Protein-tyrosine phosphatase mu; PTP mu; PTPRL1; PTPRL1R-PTP-MU; PTPRM; receptor-type tyrosine-protein phosphatase mu; RPTPM; R-PTP-mu; RPTPU

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Citation for Human/Mouse/Rat PTP mu/PTPRM Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

1 Citation: Showing 1 - 1

  1. Miconazole inhibits signal transducer and activator of transcription 3 signaling by preventing its interaction with DNA damage-induced apoptosis suppressor
    Authors: SH Yoon, BK Kim, MJ Kang, JY Im, M Won
    Cancer Sci., 2020;0(0):.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot


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Isotype Controls

Reconstitution Buffers

Secondary Antibodies

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