Human NAALADase-like 2/NAALADL2 Antibody

Catalog # Availability Size / Price Qty
NAALADase‑like 2/NAALADL2 in Human Kidney.
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Human NAALADase-like 2/NAALADL2 Antibody Summary

Species Reactivity
Detects human NAALADase‑like 2/NAALADL2 in ELISAs.
Monoclonal Mouse IgG2B Clone # 817227
Protein A or G purified from hybridoma culture supernatant
Mouse myeloma cell line NS0-derived recombinant human NAALADase‑like 2/NAALADL2
Accession # Q58DX5
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.


Recommended Concentration
8-25 µg/mL
See below

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Immunohistochemistry NAALADase-like 2/NAALADL2 antibody in Human Kidney by Immunohistochemistry (IHC-P). View Larger

NAALADase‑like 2/NAALADL2 in Human Kidney. NAALADase-like 2/NAALADL2 was detected in immersion fixed paraffin-embedded sections of human kidney using Mouse Anti-Human NAALADase-like 2/ NAALADL2 Monoclonal Antibody (Catalog # MAB46651) at 15 µg/mL overnight at 4 °C. Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic (Catalog # CTS013). Tissue was stained using the Anti-Mouse HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS002) and counterstained with hematoxylin (blue). Specific staining was localized to cytoplasm of epithelial cells in convoluted tubules. View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.


Preparation and Storage

Sterile PBS to a final concentration of 0.5 mg/mL.
Reconstitution Buffer Available
Reconstitution Buffer 1 (PBS)
Catalog #
Size / Price
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: NAALADase-like 2/NAALADL2

NAALADL2 (N-acetylated alpha -linked acidic dipeptidase like 2) is a member of the peptidase M28 family of enzymes. It is presumably a type II transmembrane (TM) protein that may have O-glycosyl hydrolase activity. Human NAALADL2 is 795 amino acids (aa) in length. It is believed to contain a cytoplasmic and TM segment at the N-terminus, followed by a peptidase domain (aa 444‑596) and a TfR-like dimerization region (aa 688‑777). There are multiple splice forms. One shows a 4 aa substitution for aa 292‑795, a second shows an alternate start site at Met18 with a 24 aa substitution for aa 314‑795, and a third contains an alternate start site at Met283, accompanied by a deletion of aa 363‑411 and 633‑795. Over aa 152‑795, human NAALADL2 shares 87% and 82% aa sequence identity with mouse and canine NAALADL2, respectively.

Long Name
N-Acetylated Alpha-Linked Acidic Dipeptidase-like 2
Entrez Gene IDs
254827 (Human); 635702 (Mouse); 499583 (Rat)
Alternate Names
inactive N-acetylated-alpha-linked acidic dipeptidase-like protein 2; NAALADase L2; NAALADase like 2; NAALADase-like 2; NAALADL2; N-acetylated alpha-linked acidic dipeptidase 2; N-acetylated alpha-linked acidic dipeptidase-like 2

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Isotype Controls

Reconstitution Buffers

Secondary Antibodies

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Human NAALADase-like 2/NAALADL2 Antibody
By Anonymous on 12/26/2021
Application: IHC Sample Tested: Kidney tissue Species: Human