Human Progesterone R/NR3C3 Antibody

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Product Details
Citations (2)
Supplemental Products

Human Progesterone R/NR3C3 Antibody Summary

Species Reactivity
This antibody specifically recognizes human PR isoform A and B and cross reacts with mouse and rat PR isoform A and B. Not yet tested in other species.
Monoclonal Mouse IgG2A Clone # A9621A
Protein A or G purified from hybridoma culture supernatant
Recombinant human Progesterone R/NR3C3 Isoform A
aa 166-263
A liquid formulation in physiologic saline with 0.1% NaN3


Recommended Concentration
Western Blot
This antibody can be used at 1 μg/mL under reducing andnon-reducing conditions with the appropriate secondary reagents to detecthuman PR.
This antibody can be used at 10 - 20 μg/mL withthe appropriate secondary reagents to detect human PR.
Optimal dilutions should be determined by eachlaboratory.
Direct ELISA
This antibody can be used at 10 ng/mL with the appropriatesecondary reagents to detect human PR.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
This antibody is stable for greater than six months when held at -20 °C in a manual defrost freezer or at -70 °C. Upon thawing, the antibody can be stored at 2-8 °C for at least 1 month without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Background: Progesterone R/NR3C3

Progesterone receptor (PR; NR3C3) is a member of the Steroid Receptor family. PR binds progesterone. PR is expressed in the uterus, ovary, vagina, fallopian tubes and breast. PR plays a central role in diverse reproductive events associated with establishment and maintenance of pregnancy, alveolar development in the breast and sexual behavior. Two isoforms of this receptor have been identified, PR-A and PR-B, 94 and 114 kDa in size, respectively.

Long Name
Progesterone Receptor
Entrez Gene IDs
5241 (Human)
Alternate Names
NR3C3; NR3C3PRNuclear receptor subfamily 3 group C member 3; PGR; Progesterone R; progesterone receptor; ProgesteroneR

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Citations for Human Progesterone R/NR3C3 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

2 Citations: Showing 1 - 2
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  1. Disposable Amperometric Immunosensor for the Determination of Human P53 Protein in Cell Lysates Using Magnetic Micro-Carriers
    Authors: José M Pingarrón
    Biosensors (Basel), 2016;6(4):.
    Applications: SDS-Page
  2. Evidence for a Mullerian-inhibiting substance autocrine/paracrine system in adult human endometrium.
    Authors: Wang J, Dicken C, Lustbader JW, Tortoriello DV
    Fertil. Steril., 2009;91(4):1195-203.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC


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Isotype Controls

Mouse IgG2A Isotype Control

Secondary Antibodies

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