Human Progesterone R/NR3C3 Antibody

R&D Systems | Catalog # PP-A9621A-00

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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Immunohistochemistry, Western Blot, Direct ELISA, Immunoprecipitation

Cited:

Immunocytochemistry, SDS-Page

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2A Clone # A9621A
View all Progesterone R/NR3C3 Primary Antibodies »

Product Specifications

Immunogen

Recombinant human Progesterone R/NR3C3 Isoform A
aa 166-263

Specificity

This antibody specifically recognizes human PR isoform A and B and cross reacts with mouse and rat PR isoform A and B. Not yet tested in other species.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Applications for Human Progesterone R/NR3C3 Antibody

Application
Recommended Usage

Direct ELISA

This antibody can be used at 10 ng/mL with the appropriate secondary reagents to detect human PR.

Immunohistochemistry

This antibody can be used at 10 - 20 μg/mL with the appropriate secondary reagents to detect human PR.

Immunoprecipitation

Optimal dilutions should be determined by each laboratory.

Western Blot

This antibody can be used at 1 μg/mL under reducing and non-reducing conditions with the appropriate secondary reagents to detect human PR.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

A liquid formulation in physiologic saline with 0.1% NaN3

Shipping

The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

This antibody is stable for greater than six months when held at -20 °C in a manual defrost freezer or at -70 °C. Upon thawing, the antibody can be stored at 2-8 °C for at least 1 month without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Background: Progesterone R/NR3C3

Progesterone receptor (PR; NR3C3) is a member of the Steroid Receptor family. PR binds progesterone. PR is expressed in the uterus, ovary, vagina, fallopian tubes and breast. PR plays a central role in diverse reproductive events associated with establishment and maintenance of pregnancy, alveolar development in the breast and sexual behavior. Two isoforms of this receptor have been identified, PR-A and PR-B, 94 and 114 kDa in size, respectively.

Long Name

Progesterone Receptor

Alternate Names

NR3C3, PGR, ProgesteroneR

Entrez Gene IDs

5241 (Human)

Gene Symbol

PGR

Additional Progesterone R/NR3C3 Products

Product Documents for Human Progesterone R/NR3C3 Antibody

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Human Progesterone R/NR3C3 Antibody

For research use only

Citations for Human Progesterone R/NR3C3 Antibody

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Protocols

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FAQs

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