Human SCF/c-kit Ligand Antibody
Human SCF/c-kit Ligand Antibody Summary
Accession # P21583
Human SCF/c-kit Ligand Sandwich Immunoassay
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: SCF/c-kit Ligand
SCF, also known as c-kit ligand, mast cell growth factor (MGF) and steel-factor (SLF), is a pleiotropic cytokine that plays essential roles in gametogenesis, melanogenesis and early stages of hematopoiesis. SCF can exist either as a membrane bound form or as a soluble form consisting of the first 164 or 165 amino acids of the extracellular domain.
Citations for Human SCF/c-kit Ligand Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
Citations: Showing 1 - 4
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Human airway smooth muscle promotes human lung mast cell survival, proliferation, and constitutive activation: cooperative roles for CADM1, stem cell factor, and IL-6.
Authors: Hollins F, Kaur D, Yang W, Cruse G, Saunders R, Sutcliffe A, Berger P, Ito A, Brightling CE, Bradding P
J. Immunol., 2008;181(4):2772-80.
Sample Types: Whole Cells
Isolation and characterization of CD146+ multipotent mesenchymal stromal cells.
Authors: Sorrentino A, Ferracin M, Castelli G, Biffoni M, Tomaselli G, Baiocchi M, Fatica A, Negrini M, Peschle C, Valtieri M
Exp. Hematol., 2008;36(8):1035-46.
Sample Types: Cell Lysates
Applications: Western Blot
C-KIT, by interacting with the membrane-bound ligand, recruits endothelial progenitor cells to inflamed endothelium.
Authors: Dentelli P, Rosso A, Balsamo A, Colmenares Benedetto S, Zeoli A, Pegoraro M, Camussi G, Pegoraro L, Brizzi MF
Sample Types: Whole Cells
Inhibition by glucocorticoids of the interleukin-1beta-enhanced expression of the mast cell growth factor SCF.
Authors: Da Silva CA, 2019, Kassel O, Mathieu E, Massard G, Gasser B, Frossard N
Sample Types: Cell Culture Supernates
Applications: ELISA Development
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