Human VDR/NR1I1 Antibody
Human VDR/NR1I1 Antibody Summary
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Preparation and Storage
Vitamin D Receptor (VDR; NR1I1) is a member of the Steroid Receptor family related to the Pregnane X Receptor (PXR) and Constitutive Androstane Receptors (CARs). The natural ligand of VDR is 1, 25 di-hydroxyvitamin D3. VDR is expressed in osteoblasts, osteocytes, osteoclasts, bone, bone marrow, thymus and small intestine. VDR plays critical roles in calcium homeostasis, bone development and mineralization, as well as control of cell growth and differentiation. Retnoid X Receptors (RXRs) are the major partners for VDR since by heterodimerizing with VDR, they increase their DNA-binding affinity and select the correct spacing of direct repeat elements.
Citations for Human VDR/NR1I1 Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
Citations: Showing 1 - 2
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Response of Npt2a knockout mice to dietary calcium and phosphorus
Authors: Y Li, D Caballero, J Ponsetto, A Chen, C Zhu, J Guo, M Demay, H Jüppner, C Bergwitz
PLoS ONE, 2017;12(4):e0176232.
Sample Types: Serum
Cutting edge: progesterone directly upregulates vitamin d receptor gene expression for efficient regulation of T cells by calcitriol.
Authors: Thangamani S, Kim M, Son Y, Huang X, Kim H, Lee J, Cho J, Ulrich B, Broxmeyer H, Kim C
J Immunol, 2015;194(3):883-6.
Sample Types: Cell Lysates
Applications: Western Blot
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