Mouse IFN-gamma DuoSet ELISA Summary
* Provided that the recommended microplates, buffers, diluents, substrates and solutions are used, and the assay is run as summarized in the Assay Procedure provided.
This DuoSet ELISA Development kit contains the basic components required for the development of sandwich ELISAs to measure natural and recombinant mouse IFN-gamma. The suggested diluent is suitable for the analysis of most cell culture supernate samples. Diluents for complex matrices, such as serum and plasma, should be evaluated prior to use in this DuoSet.
Product Features
- Optimized capture and detection antibody pairings with recommended concentrations save lengthy development time
- Development protocols are provided to guide further assay optimization
- Assay can be customized to your specific needs
- Economical alternative to complete kits
Kit Content
- Capture Antibody
- Detection Antibody
- Recombinant Standard
- Streptavidin conjugated to horseradish-peroxidase (Streptavidin-HRP)
Other Reagents Required
DuoSet Ancillary Reagent Kit 2 (5 plates): (Catalog # DY008) containing 96 well microplates, plate sealers, substrate solution, stop solution, plate coating buffer (PBS), wash buffer, and Reagent Diluent Concentrate 2.
The components listed above may be purchased separately:
PBS: (Catalog # DY006), or 137 mM NaCl, 2.7 mM KCl, 8.1 mM Na2HPO4, 1.5 mM KH2PO4, pH 7.2 - 7.4, 0.2 µm filtered
Wash Buffer: (Catalog # WA126), or 0.05% Tween® 20 in PBS, pH 7.2-7.4
Block Buffer: (Catalog # DY995), or 1% BSA in PBS, pH 7.2-7.4, 0.2 µm filtered
Reagent Diluent: 0.1% BSA, 0.05% Tween 20 in Tris-buffered Saline (20 mM Trizma base, 150 mM NaCI) pH 7.2-7.4, 0.2 μm filtered
Substrate Solution: 1:1 mixture of Color Reagent A (H2O2) and Color Reagent B (Tetramethylbenzidine) (Catalog # DY999)
Stop Solution: 2 N H2SO4 (Catalog # DY994)
Microplates: R&D Systems (Catalog # DY990)
Plate Sealers: ELISA Plate Sealers (Catalog # DY992)
Data Example
Product Datasheets
Preparation and Storage
Background: IFN-gamma
IFN-gamma (Interferon-gamma) is the prototype proinflammatory cytokine and is produced by a variety of immune cells under inflammatory conditions, notably by T cells and NK cells. It plays a key role in host defense by promoting the development and activation of Th1 cells, chemoattraction and activation of monocytes and macrophages, upregulation of antigen presentation molecules, and immunoglobulin class switching in B cells. It also exhibits antiviral, antiproliferative, and apoptotic effects. In addition, IFN-gamma functions as an anti-inflammatory mediator by promoting the development of regulatory T cells and inhibiting Th17 cell differentiation. IFN-gamma dimers signal through a receptor complex of two IFN-gamma R1 and two IFN-gamma R2 subunits.
Assay Procedure
GENERAL ELISA PROTOCOL
Plate Preparation
- Dilute the Capture Antibody to the working concentration in PBS without carrier protein. Immediately coat a 96-well microplate with 100 μL per well of the diluted Capture Antibody. Seal the plate and incubate overnight at room temperature.
- Aspirate each well and wash with Wash Buffer, repeating the process two times for a total of three washes. Wash by filling each well with Wash Buffer (400 μL) using a squirt bottle, manifold dispenser, or autowasher. Complete removal of liquid at each step is essential for good performance. After the last wash, remove any remaining Wash Buffer by aspirating or by inverting the plate and blotting it against clean paper towels.
- Block plates by adding 300 μL of Block Buffer to each well. Incubate at room temperature for a minimum of 1 hour.
- Repeat the aspiration/wash as in step 2. The plates are now ready for sample addition.
Assay Procedure
- Add 100 μL of sample or standards in Reagent Diluent, or an appropriate diluent, per well. Cover with an adhesive strip and incubate 2 hours at room temperature.
- Repeat the aspiration/wash as in step 2 of Plate Preparation.
- Add 100 μL of the Detection Antibody, diluted in Reagent Diluent, to each well. Cover with a new adhesive strip and incubate 2 hours at room temperature.
- Repeat the aspiration/wash as in step 2 of Plate Preparation.
- Add 100 μL of the working dilution of Streptavidin-HRP to each well. Cover the plate and incubate for 20 minutes at room temperature. Avoid placing the plate in direct light.
- Repeat the aspiration/wash as in step 2.
- Add 100 μL of Substrate Solution to each well. Incubate for 20 minutes at room temperature. Avoid placing the plate in direct light.
- Add 50 μL of Stop Solution to each well. Gently tap the plate to ensure thorough mixing.
- Determine the optical density of each well immediately, using a microplate reader set to 450 nm. If wavelength correction is available, set to 540 nm or 570 nm. If wavelength correction is not available, subtract readings at 540 nm or 570 nm from the readings at 450 nm. This subtraction will correct for optical imperfections in the plate. Readings made directly at 450 nm without correction may be higher and less accurate.
Citations for Mouse IFN-gamma DuoSet ELISA
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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ADP-ribosylating adjuvant reveals plasticity in cDC1 cells that drive mucosal Th17 cell development and protection against influenza virus infection
Authors: M Arabpour, C Lebrero-Fe, K Schön, A Strömberg, V Börjesson, K Lahl, M Ballegeer, X Saelens, D Angeletti, W Agace, N Lycke
Mucosal Immunology, 2022;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
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Anti-CD80/86 antibodies inhibit inflammatory reaction and improve graft survival in a high-risk murine corneal transplantation rejection model
Authors: J Zhu, T Inomata, M Nakamura, K Fujimoto, Y Akasaki, K Fujio, A Yanagawa, K Uchida, J Sung, N Negishi, K Nagino, Y Okumura, M Miura, H Shokirova, M Kuwahara, K Hirosawa, A Midorikawa, A Eguchi, T Huang, H Yagita, S Habu, K Okumura, A Murakami
Scientific Reports, 2022;12(1):4853.
Species: Mouse
Sample Types: Cell Culture Supernates
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Menthone Inhalation Alleviates Local and Systemic Allergic Inflammation in Ovalbumin-Sensitized and Challenged Asthmatic Mice
Authors: YH Su, JY Lin
International Journal of Molecular Sciences, 2022;23(7):.
Species: Mouse
Sample Types: BALF
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Coordination of asparagine uptake and asparagine synthetase expression modulates CD8+ T cell activation
Authors: HC Hope, RJ Brownlie, CM Fife, L Steele, M Lorger, RJ Salmond
JCI Insight, 2021;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
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Expression of IL-20 Receptor Subunit beta Is Linked to EAE Neuropathology and CNS Neuroinflammation
Authors: JR Dayton, Y Yuan, LP Pacumio, BG Dorflinger, SC Yoo, MJ Olson, SI Hernández-, MM McMahon, L Cruz-Oreng
Frontiers in Cellular Neuroscience, 2021;15(0):683687.
Species: Mouse
Sample Types: Tissue Homogenates
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Gut microbiota-mediated secondary bile acids regulate dendritic cells to attenuate autoimmune uveitis through TGR5 signaling
Authors: J Hu, C Wang, X Huang, S Yi, S Pan, Y Zhang, G Yuan, Q Cao, X Ye, H Li
Cell Reports, 2021;36(12):109726.
Species: Mouse
Sample Types: Cell Culture Supernates
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Gut microbiota modulation induced by Zika virus infection in immunocompetent mice
Authors: R Corrêa, I de Oliveir, HA Braz-de-Me, LP de Sant'An, R das Neves, G Pasquarell, PS Prado, GP Kobinger, CF Maurice, KG Magalhães
Scientific Reports, 2021;11(1):1421.
Species: Mouse
Sample Types: Tissue Homogenates
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Monophosphoryl Lipid A and Poly I:C Combination Adjuvant Promoted Ovalbumin-Specific Cell Mediated Immunity in Mice Model
Authors: SY Ahn, CTT Le, EJ Ko
Biology, 2021;10(9):.
Species: Mouse
Sample Types: BALF
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Diesel exhaust particles increase nasal symptoms and IL-17A in house dust mite-induced allergic mice
Authors: HJ Jung, YK Ko, WS Shim, HJ Kim, DY Kim, CS Rhee, MK Park, DH Han
Scientific Reports, 2021;11(1):16300.
Species: Mouse
Sample Types: Cell Culture Supernates
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Fasting impairs type 2 helper T cell infiltration in the lung of an eosinophilic asthma mouse model
Authors: Y Suzuki, T Hayashi, R Yokoyama, F Nakagawa, J Inoue, T Higashi, R Onodera, K Motoyama
FEBS Open Bio, 2021;0(0):.
Species: Mouse
Sample Types: BALF
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Role of the inhibitor of serine peptidase 2 (ISP2) of Trypanosoma brucei rhodesiense in parasite virulence and modulation of the inflammatory responses of the host
Authors: DJ Levy, A Goundry, RSS Laires, TFR Costa, CM Novo, DJ Grab, JC Mottram, APCA Lima
PloS Neglected Tropical Diseases, 2021;15(6):e0009526.
Species: Mouse
Sample Types: Cell Culture Supernates
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P32-specific CAR T cells with dual antitumor and antiangiogenic therapeutic potential in gliomas
Authors: L Rousso-Noo, I Mastandrea, S Talmor, T Waks, A Globerson, M Haugas, T Teesalu, L Alvarez-Va, Z Eshhar, D Friedmann-
Nature Communications, 2021;12(1):3615.
Species: Mouse
Sample Types: Cell Culture Supernates
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Ding Chuan Tang Attenuates Airway Inflammation and Eosinophil Infiltration in Ovalbumin-Sensitized Asthmatic Mice
Authors: J Ma, MX Liu, LC Chen, JJ Shen, ML Kuo
BioMed Research International, 2021;2021(0):6692772.
Species: Mouse
Sample Types: Cell Culture Supernates
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Development of Delivery Systems Enhances the Potency of Cell-Based HIV-1 Therapeutic Vaccine Candidates
Authors: A Hadi, A Rastgoo, M Eskandaria, N Haghighipo, A Bolhassani
Journal of Immunology Research, 2021;2021(0):5538348.
Species: Mouse
Sample Types: Cell Culture Supernates
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Allergen Exposure in Murine Neonates Promoted the Development of Asthmatic Lungs
Authors: JC Chen, CC Chan, NC Ting, ML Kuo
Biomedicines, 2021;9(6):.
Species: Mouse
Sample Types: Cell Culture Supernates
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The Adjuvants Polyphosphazene (PCEP) and a Combination of Curdlan Plus Leptin Promote a Th17-Type Immune Response to an Intramuscular Vaccine in Mice
Authors: A Chaffey, G Hamonic, D Chand, GK Mutwiri, HL Wilson
Vaccines, 2021;9(5):.
Species: Mouse
Sample Types: Cell Culture Supernates
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Ex Vivo-Induced Bone Marrow-Derived Myeloid Suppressor Cells Prevent Corneal Allograft Rejection in Mice
Authors: J Zhu, T Inomata, K Fujimoto, K Uchida, K Fujio, K Nagino, M Miura, N Negishi, Y Okumura, Y Akasaki, K Hirosawa, M Kuwahara, A Eguchi, H Shokirova, A Yanagawa, A Midorikawa, A Murakami
Investigative Ophthalmology & Visual Science, 2021;62(7):3.
Species: Mouse
Sample Types: Cell Culture Supernates
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Anti-inflammatory Effects of Empagliflozin and Gemigliptin on LPS-Stimulated Macrophage via the IKK/NF-&kappaB, MKK7/JNK, and JAK2/STAT1 Signalling Pathways
Authors: N Lee, YJ Heo, SE Choi, JY Jeon, SJ Han, DJ Kim, Y Kang, KW Lee, HJ Kim
Journal of Immunology Research, 2021;2021(0):9944880.
Species: Mouse
Sample Types: Cell Culture Supernates
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Microfluidics sorting enables the isolation of an intact cellular pair complex of CD8+ T cells and antigen-presenting cells in a cognate antigen recognition-dependent manner
Authors: S Kuwabara, Y Tanimoto, M Okutani, M Jie, Y Haseda, Y Kinugasa-K, T Aoshi
PLoS ONE, 2021;16(6):e0252666.
Species: Mouse
Sample Types: Cell Culture Supernates
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Opisthorchis viverrini antigens up-regulates the expression of CD80 and MHC class II in JAWSII mouse dendritic cells and promotes IL-10 and TGF-&beta secretions
Authors: S Jittimanee, S Wongratana, C Kaewraemru, J Jittimanee
Parasitology international, 2021;84(0):102401.
Species: Mouse
Sample Types: Cell Culture Supernates
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Anti-parasitic activity of Annona muricata L. leaf ethanolic extract and its fractions against Toxoplasma gondii in vitro and in vivo
Authors: NC Miranda, EC Borges Ara, AB Justino, Y Cariaco, CM Mota, LA Costa-Nasc, FS Espindola, NM Silva
Journal of ethnopharmacology, 2021;0(0):114019.
Species: Mouse
Sample Types: Serum
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CIS-platin increases immune activity of monocytes and cytotoxic T-cells in a murine model of epithelial ovarian cancer
Authors: D Hopkins, H Sanchez, BB PhD, IW Md
Translational Oncology, 2021;14(12):101217.
Species: Mouse
Sample Types: Cell Culture Supernates
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VEGFR2 activity on myeloid cells mediates immune suppression in the tumor microenvironment
Authors: Y Zhang, H Huang, M Coleman, A Ziemys, P Gopal, SM Kazmi, RA Brekken
JCI Insight, 2021;6(23):.
Species: Mouse
Sample Types: Tissue Homogenates
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Potent antitumor effects of cell-penetrating peptides targeting STAT3 axis
Authors: M Aftabizade, YJ Li, Q Zhao, C Zhang, N Ambaye, J Song, T Nagao, C Lahtz, M Fakih, DK Ann, H Yu, A Herrmann
JCI Insight, 2021;6(2):.
Species: Mouse
Sample Types: Cell Culture Supernates
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IL-2/JES6-1 mAb complexes dramatically increase sensitivity to LPS through IFN-gamma production by CD25+Foxp3- T cells
Authors: J Tomala, P Weberova, B Tomalova, Z Jiraskova, L Sivak, J Kovarova, M Kovar
Elife, 2021;10(0):.
Species: Mouse
Sample Types: Serum
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Mitochondrial respiration contributes to the interferon gamma response in antigen-presenting cells
Authors: MC Kiritsy, K McCann, D Mott, SM Holland, SM Behar, CM Sassetti, AJ Olive
Elife, 2021;10(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
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TARM1 contributes to development of arthritis by activating dendritic cells through recognition of collagens
Authors: R Yabe, SH Chung, MA Murayama, S Kubo, K Shimizu, Y Akahori, T Maruhashi, A Seno, T Kaifu, S Saijo, Y Iwakura
Nature Communications, 2021;12(1):94.
Species: Mouse
Sample Types: Cell Culture Supernates
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Development of combination adjuvant for efficient T cell and antibody response induction against protein antigen
Authors: Y Haseda, L Munakata, C Kimura, Y Kinugasa-K, Y Mori, R Suzuki, T Aoshi
PLoS ONE, 2021;16(8):e0254628.
Species: Mouse
Sample Types: Cell Culture Supernates
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Endangered Lymphocytes: The Effects of Alloxan and Streptozotocin on Immune Cells in Type 1 Induced Diabetes
Authors: LAD Queiroz, JB Assis, JPT Guimarães, ESA Sousa, AC Milhomem, KKS Sunahara, A Sá-Nunes, JO Martins
Mediators of Inflammation, 2021;2021(0):9940009.
Species: Mouse
Sample Types: Tissue Homogenates
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Geographic differences in gut microbiota composition impact susceptibility to enteric infection
Authors: AM Porras, Q Shi, H Zhou, R Callahan, G Montenegro, N Solomons, IL Brito
Cell Reports, 2021;36(4):109457.
Species: Mouse
Sample Types: Tissue Supernates
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NLRP1 acts as a negative regulator of Th17 cell programming in mice and humans with autoimmune diabetes
Authors: FRC Costa, JA Leite, DM Rassi, JF da Silva, J Elias-Oliv, JB Guimarães, MC Foss-Freit, NOS Câmara, A Pontillo, RC Tostes, JS Silva, D Carlos
Cell Reports, 2021;35(8):109176.
Species: Mouse
Sample Types: Tissue Homogenates
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Topical administration of the kappa opioid receptor agonist nalfurafine suppresses corneal neovascularization and inflammation
Authors: H Shokirova, T Inomata, T Saitoh, J Zhu, K Fujio, Y Okumura, A Yanagawa, K Fujimoto, J Sung, A Eguchi, M Miura, K Nagino, K Hirosawa, M Kuwahara, Y Akasaki, H Nagase, A Murakami
Scientific Reports, 2021;11(1):8647.
Species: Mouse
Sample Types: Tissue Homogenates
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Oligodeoxynucleotides containing unmethylated cytosine-guanine motifs are effective immunostimulants against pneumococcal meningitis in the immunocompetent and neutropenic host
Authors: S Ribes, L Zacke, S Nessler, N Saiepour, E Avendaño-G, M Ballüer, UK Hanisch, R Nau
Journal of Neuroinflammation, 2021;18(1):39.
Species: Mouse
Sample Types: Tissue Homogenates
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Brucella ovis mutant in ABC transporter protects against Brucella canis infection in mice and it is safe for dogs
Authors: C Eckstein, JPS Mol, FB Costa, PP Nunes, PA Lima, MM Melo, TP Carvalho, DO Santos, MF Silva, TF Carvalho, LF Costa, OAO Melo Júnio, RC Giunchette, TA Paixão, RL Santos
PLoS ONE, 2020;15(4):e0231893.
Species: Mouse
Sample Types: Cell Culture Supernates
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In silico analysis and in vivo assessment of a novel epitope-based vaccine candidate against uropathogenic Escherichia coli
Authors: S Hasanzadeh, M Habibi, MA Shokrgozar, R Ahangari C, K Ahmadi, MR Asadi Kara, S Bouzari
Sci Rep, 2020;10(1):16258.
Species: Mouse
Sample Types: Cell Culture Supernates
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Aptamer targeted therapy potentiates immune checkpoint blockade in triple-negative breast cancer
Authors: S Camorani, M Passariell, L Agnello, S Esposito, F Collina, M Cantile, M Di Bonito, IV Ulasov, M Fedele, A Zannetti, C De Lorenzo, L Cerchia
J. Exp. Clin. Cancer Res., 2020;39(1):180.
Species: Mouse
Sample Types: Cell Culture Supernates
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Dietary Fructose Alters the Composition, Localization and Metabolism of Gut Microbiota in Association with Worsening Colitis
Authors: DC Montrose, R Nishiguchi, S Basu, HA Staab, XK Zhou, H Wang, L Meng, M Johncilla, JR Cubillos-R, DK Morales, MT Wells, KW Simpson, S Zhang, B Dogan, C Jiao, Z Fei, A Oka, JW Herzog, RB Sartor, AJ Dannenberg
Cell Mol Gastroenterol Hepatol, 2020;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
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Pre-treatment with the viral Toll-like receptor 3 agonist poly(I:C) modulates innate immunity and protects neutropenic mice infected intracerebrally with Escherichia coli
Authors: S Ribes, C Arcilla, M Ott, S Schütze, UK Hanisch, S Nessler, R Nau
J Neuroinflammation, 2020;17(1):24.
Species: Mouse
Sample Types: Tissue Homogenates
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Strain-Specific Differences in House Dust Mite (Dermatophagoides farinae)-Induced Mouse Models of Allergic Rhinitis
Authors: KI Lee, JS Bae, EH Kim, JH Kim, L Lyu, YJ Chung, JH Mo
Clin Exp Otorhinolaryngol, 2020;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
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Combination therapy using human papillomavirus L1/E6/E7 genes and archaeosome: a nanovaccine confer immuneadjuvanting effects to fight cervical cancer
Authors: H Karimi, H Soleimanja, A Abdoli, RS Banijamali
Sci Rep, 2020;10(1):5787.
Species: Mouse
Sample Types: Cell Culture Supernates
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The Role of ST2 Receptor in the Regulation of Brucella abortus Oral Infection
Authors: R Santos, PC Campos, M Rungue, V Rocha, D Santos, V Mendes, FV Marinho, F Martins, MF Ricci, DCD Reis, GD Cassali, JC Alves-Filh, AT Vieira, SC Oliveira
Pathogens, 2020;9(5):.
Species: Mouse
Sample Types: Cell Culture Supernates
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Modifying bacterial flagellin to evade Nod-like Receptor CARD 4 recognition enhances protective immunity against Salmonella
Authors: P Tourlomous, JA Wright, AS Bittante, LJ Hopkins, SJ Webster, OJ Bryant, P Mastroeni, DJ Maskell, CE Bryant
Nat Microbiol, 2020;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
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Comprehensive Screening of Mouse T-Cell Epitopes in Human Herpesvirus 6B Glycoprotein H/L/Q1/Q2 Tetramer Complex
Authors: M Okutani, A Kawabata, M Nishimura, S Nagamata, S Kuwabara, Y Haseda, L Munakata, R Suzuki, Y Mori, T Aoshi
J Immunol Res, 2020;2020(0):4697529.
Species: Mouse
Sample Types: Cell Culture Supernates
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High-dose intranasal application of titanium dioxide nanoparticles induces the systemic uptakes and allergic airway inflammation in asthmatic mice
Authors: S Abdulnasse, M Hannig, DD Le, S Heck, M Leitner, AJ Omlor, I Tavernaro, A Kraegeloh, R Kautenburg, G Kickelbick, A Beilhack, M Bischoff, J Nguyen, M Sester, R Bals, QT Dinh
Respir. Res., 2020;21(1):168.
Species: Mouse
Sample Types: Serum
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Tofacitinib treatment aggravates Staphylococcus aureus septic arthritis, but attenuates sepsis and enterotoxin induced shock in mice
Authors: A Jarneborn, M Mohammad, C Engdahl, Z Hu, M Na, A Ali, T Jin
Sci Rep, 2020;10(1):10891.
Species: Mouse
Sample Types: Serum
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The Exopolysaccharide of Lactobacillus fermentum UCO-979C Is Partially Involved in Its Immunomodulatory Effect and Its Ability to Improve the Resistance against Helicobacter pylori Infection
Authors: V Garcia-Cas, G Marcial, L Albarracín, M Tomokiyo, P Clua, H Takahashi, H Kitazawa, A Garcia-Can, J Villena
Microorganisms, 2020;8(4):.
Species: Mouse
Sample Types: Cell Culture Supernates
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Nucleic Acid-Sensing Toll-Like Receptors Play a Dominant Role in Innate Immune Recognition of Pneumococci
Authors: A Famà, A Midiri, G Mancuso, C Biondo, G Lentini, R Galbo, MM Giardina, GV De Gaetano, L Romeo, G Teti, C Beninati
MBio, 2020;11(2):.
Species: Mouse
Sample Types: Tissue Lysates
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Epigenetic therapy inhibits metastases by disrupting premetastatic niches
Authors: Z Lu, J Zou, S Li, MJ Topper, Y Tao, H Zhang, X Jiao, W Xie, X Kong, M Vaz, H Li, Y Cai, L Xia, P Huang, K Rodgers, B Lee, JB Riemer, CP Day, RC Yen, Y Cui, Y Wang, Y Wang, W Zhang, H Easwaran, A Hulbert, K Kim, RA Juergens, SC Yang, RJ Battafaran, EL Bush, SR Broderick, SM Cattaneo, JR Brahmer, CM Rudin, J Wrangle, Y Mei, YJ Kim, B Zhang, KK Wang, PM Forde, JB Margolick, BD Nelkin, CA Zahnow, DM Pardoll, F Housseau, SB Baylin, L Shen, MV Brock
Nature, 2020;0(0):.
Species: Mouse
Sample Types: Cell culture supernate
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T cell-intrinsic role for Nod2 in protection against Th17-mediated uveitis
Authors: RJ Napier, EJ Lee, MP Davey, EE Vance, JM Furtado, PE Snow, KA Samson, SJ Lashley, BR Brown, R Horai, MJ Mattapalli, B Xu, MC Callegan, LS Uebelhoer, CL Lancioni, RK Vehe, BA Binstadt, JR Smith, RR Caspi, HL Rosenzweig
Nat Commun, 2020;11(1):5406.
Species: Mouse
Sample Types: Cell Lysates
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Respiratory syncytial virus infection exacerbates pneumococcal pneumonia via Gas6/Axl-mediated macrophage polarization
Authors: T Shibata, A Makino, R Ogata, S Nakamura, T Ito, K Nagata, Y Terauchi, T Oishi, M Fujieda, Y Takahashi, M Ato
J. Clin. Invest., 2020;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
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Combination of Innate Immune Modulators as Vaccine Adjuvants in Mice
Authors: A Haddadi, A Chaffey, SH Ng, D Yalamati, HL Wilson
Vaccines (Basel), 2020;8(4):.
Species: Mouse
Sample Types: Cell Culture Supernates
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Parkinson's disease-associated kinase LRRK2 regulates genes required for cell adhesion, polarization, and chemotaxis in activated murine macrophages
Authors: DR Levy, A Udgata, P Tourlomous, MF Symmons, LJ Hopkins, CE Bryant, NJ Gay
J. Biol. Chem., 2020;0(0):.
Species: Mouse
Sample Types: Serum
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Myeloid-derived suppressor cells therapy enhance immunoregulatory properties in acute graft versus host disease with combination of regulatory T cells
Authors: MJ Park, JA Baek, SY Kim, KA Jung, JW Choi, SH Park, SK Kwok, ML Cho
Journal of Translational Medicine, 2020;18(1):483.
Species: Mouse
Sample Types: Cell Culture Supernates
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TXNIP Regulates Natural Killer Cell-Mediated Innate Immunity by Inhibiting IFN-&gamma Production during Bacterial Infection
Authors: DO Kim, JE Byun, WS Kim, MJ Kim, JH Choi, H Kim, E Choi, TD Kim, SR Yoon, JY Noh, YJ Park, J Lee, HJ Cho, HG Lee, SH Min, I Choi, H Jung
International Journal of Molecular Sciences, 2020;21(24):.
Species: Mouse
Sample Types: Serum
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The Impact of Focused Ultrasound in Two Tumor Models: Temporal Alterations in the Natural History on Tumor Microenvironment and Immune Cell Response
Authors: G Cohen, P Chandran, RM Lorsung, LE Tomlinson, M Sundby, SR Burks, JA Frank
Cancers (Basel), 2020;12(2):.
Species: Mouse
Sample Types: Cell Culture Supernates
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Anti-Axl antibody treatment reduces the severity of experimental autoimmune encephalomyelitis
Authors: JC DuBois, AK Ray, P Davies, B Shafit-Zag
J Neuroinflammation, 2020;17(1):324.
Species: Mouse
Sample Types: Cell Culture Supernates
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Isolation of Two Novel Human Anti-CTLA-4 mAbs with Intriguing Biological Properties on Tumor and NK Cells
Authors: M Passariell, C Vetrei, E Sasso, G Froechlich, C Gentile, AM D'Alise, N Zambrano, E Scarselli, A Nicosia, C De Lorenzo
Cancers (Basel), 2020;12(8):.
Species: Mouse
Sample Types: Cell Culture Supernates
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Head-to-head comparisons of Toxoplasma gondii and its near relative Hammondia hammondi reveal dramatic differences in the host response and effectors with species-specific functions
Authors: ZS Wong, SL Sokol-Borr, P Olias, JP Dubey, JP Boyle
PLoS Pathog., 2020;16(6):e1008528.
Species: Mouse
Sample Types: Cell Culture Supernates
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Antileishmanial activity of a new chloroquine analog in an animal model of Leishmania panamensis infection
Authors: L Herrera, A Llanes, J Álvarez, K Degracia, CM Restrepo, R Rivera, DE Stephens, HT Dang, OV Larionov, R Lleonart, PL Fernández
Int J Parasitol Drugs Drug Resist, 2020;14(0):56-61.
Species: Mouse
Sample Types: Cell Culture Supernates
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Microfluidic-prepared DOTAP nanoparticles induce strong T-cell responses in mice
Authors: Y Haseda, L Munakata, J Meng, R Suzuki, T Aoshi
PLoS ONE, 2020;15(1):e0227891.
Species: Mouse
Sample Types: Cell Culture Supernates
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Skeletal muscle antagonizes antiviral CD8+ T cell exhaustion
Authors: J Wu, N Weisshaar, A Hotz-Wagen, A Madi, S Ma, A Mieg, M Hering, K Mohr, T Schlimbach, H Borgers, G Cui
Sci Adv, 2020;6(24):eaba3458.
Species: Mouse
Sample Types: Serum
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Restricting Glycolysis Preserves T Cell Effector Functions and Augments Checkpoint Therapy
Authors: K Renner, C Bruss, A Schnell, G Koehl, HM Becker, M Fante, AN Menevse, N Kauer, R Blazquez, L Hacker, SM Decking, T Bohn, S Faerber, K Evert, L Aigle, S Amslinger, M Landa, O Krijgsman, EA Rozeman, C Brummer, PJ Siska, K Singer, S Pektor, M Miederer, K Peter, E Gottfried, W Herr, I Marchiq, J Pouyssegur, WR Roush, S Ong, S Warren, T Pukrop, P Beckhove, SA Lang, T Bopp, CU Blank, JL Cleveland, PJ Oefner, K Dettmer, M Selby, M Kreutz
Cell Rep, 2019;29(1):135-150.e9.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Macrophage migration inhibitory factor enhances influenza-associated mortality in mice
Authors: CA Smith, DJ Tyrell, UA Kulkarni, S Wood, L Leng, RL Zemans, R Bucala, DR Goldstein
JCI Insight, 2019;4(13):.
Species: Mouse
Sample Types: Serum
-
Sterile Lung Inflammation Induced by Silica Exacerbates Mycobacterium tuberculosis Infection via STING-Dependent Type 2 Immunity
Authors: S Benmerzoug, B Bounab, S Rose, D Gosset, F Biet, T Cochard, A Xavier, N Rouxel, L Fauconnier, WGC Horsnell, B Ryffel, D Togbe, VFJ Quesniaux
Cell Rep, 2019;27(9):2649-2664.e5.
Species: Mouse
Sample Types: Tissue Homogenates
-
The immunoreceptor CD300a controls the intensity of inflammation and dysfunction in a model of Ag-induced arthritis in mice
Authors: BVS Valiate, RU Alvarez, L Karra, CM Queiroz-Jú, FA Amaral, F Levi-Schaf, MM Teixeira
J. Leukoc. Biol., 2019;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Alpha-galactosylceramide enhances mucosal immunity to oral whole-cell cholera vaccines
Authors: CJH Davitt, S Longet, A Albutti, V Aversa, S Nordqvist, B Hackett, CP McEntee, M Rosa, IS Coulter, M Lebens, J Tobias, J Holmgren, EC Lavelle
Mucosal Immunol, 2019;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
DNA threads released by activated CD4+ T lymphocytes provide autocrine costimulation
Authors: M Costanza, PL Poliani, P Portararo, B Cappetti, S Musio, F Pagani, L Steinman, MP Colombo, R Pedotti, S Sangaletti
Proc. Natl. Acad. Sci. U.S.A., 2019;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Gut microbiota modulate dendritic cell antigen presentation and radiotherapy-induced antitumor immune response
Authors: M Uribe-Herr, S Rafail, S Beghi, L Gil-de-Góm, I Verginadis, K Bittinger, S Pustylniko, S Pierini, R Perales-Li, IA Blair, CA Mesaros, NW Snyder, F Bushman, C Koumenis, A Facciabene
J. Clin. Invest., 2019;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Human metapneumovirus activates NOD-like receptor protein 3 inflammasome via its small hydrophobic protein which plays a detrimental role during infection in mice
Authors: VB Lê, J Dubois, C Couture, MH Cavanagh, O Uyar, A Pizzorno, M Rosa-Calat, MÈ Hamelin, G Boivin
PLoS Pathog., 2019;15(4):e1007689.
Species: Mouse
Sample Types: BALF
-
A rationally designed peptide antagonist of the PD-1 signaling pathway as an immunomodulatory agent for cancer therapy
Authors: PG Sasikumar, RK Ramachandr, S Adurthi, AA Dhudashia, S Vadlamani, K Vemula, S Vunnum, LK Satyam, DS Samiulla, K Subbarao, R Nair, R Shrimali, N Gowda, M Ramachandr
Mol. Cancer Ther., 2019;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Anti-leishmanial activity of Brevinin 2R and its Lauric acid conjugate type against L. major: In vitro mechanism of actions and in vivo treatment potentials
Authors: F Zahedifard, H Lee, JH No, M Salimi, N Seyed, A Asoodeh, S Rafati
PLoS Negl Trop Dis, 2019;13(2):e0007217.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Modifying internal organization and surface morphology of siRNA lipoplexes by sodium alginate addition for efficient siRNA delivery
Authors: DC Arruda, IJ Gonzalez, S Finet, L Cordova, V Trichet, GF Andrade, C Hoffmann, P Bigey, WA de Almeida, A Da Silva C, A Malachias, V Escriou
J Colloid Interface Sci, 2019;540(0):342-353.
Species: Mouse
Sample Types: Serum
-
Rorc restrains the potency of ST2+ regulatory T cells in ameliorating intestinal graft-versus-host disease
Authors: J Yang, A Ramadan, DK Reichenbac, M Loschi, J Zhang, B Griesenaue, H Liu, KL Hippen, BR Blazar, S Paczesny
JCI Insight, 2019;0(0):.
Species: Mouse
Sample Types: Plasma
-
Immunomodulatory effect of Syphacia obvelata in treatment of experimental DSS-induced colitis in mouse model
Authors: N Taghipour, N Mosaffa, HA Aghdaei, M Rostami-Ne, JV Weinstock, S Shahnavaz, MR Zali
Sci Rep, 2019;9(1):19127.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Rapid synthesis and immunogenicity of mycobacterial (1?5)-?-d-arabinofuranan
Authors: H Leelayuwap, S Ruchirawat, S Boonyaratt
Carbohydr Polym, 2019;206(0):262-272.
Species: Mouse
Sample Types: Cell Culture Supernates
-
DeSUMOylase SENP7-Mediated Epithelial Signaling Triggers Intestinal Inflammation via Expansion of Gamma-Delta T Cells
Authors: A Suhail, ZA Rizvi, P Mujagond, SA Ali, P Gaur, M Singh, V Ahuja, A Awasthi, CV Srikanth
Cell Rep, 2019;29(11):3522-3538.e7.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Strongyloides venezuelensis-infection alters the profile of cytokines and liver inflammation in mice co-infected with Schistosoma mansoni
Authors: MC de Rezende, JMP Moreira, LLM Fernandes, VF Rodrigues, D Negrão-Cor
Cytokine, 2019;127(0):154931.
Species: Mouse
Sample Types: Tissue Homogenates
-
Vaccination with a live-attenuated small-colony variant improves the humoral and cell-mediated responses against�Staphylococcus aureus
Authors: J Côté-Grave, E Brouillett, F Malouin
PLoS ONE, 2019;14(12):e0227109.
Species: Mouse
Sample Types: Cell Culture Supern
-
Antitumor and antioxidant effects of Clinacanthus nutans Lindau in 4?T1 tumor-bearing mice
Authors: NMA Nik Abd Ra, MY Nurliyana, MNFNN Afiqah, MA Osman, M Hamid, MAM Lila
BMC Complement Altern Med, 2019;19(1):340.
Species: Mouse
Sample Types: Serum
-
Canonical PI3K? signaling in myeloid cells restricts Trypanosoma cruzi infection and dampens chagasic myocarditis
Authors: MC Silva, M Davoli-Fer, TS Medina, R Sesti-Cost, GK Silva, CD Lopes, LE Cardozo, FN Gava, K Lyroni, FC Dias, AF Frade, M Baron, HI Nakaya, F Figueiredo, JC Alves-Filh, FQ Cunha, C Tsatsanis, C Chevillard, E Cunha-Neto, E Hirsch, JS Silva, TM Cunha
Nat Commun, 2018;9(1):1513.
Species: Mouse
Sample Types: Serum
-
Integration of T Cell Receptor, Notch and Cytokine Signals Programs in Mouse ?? T Cell Effector Differentiation
Authors: P Zarin, TSH In, ELY Chen, J Singh, GW Wong, M Mohtashami, DL Wiest, MK Anderson, JC Zúñiga-Pfl
Immunol. Cell Biol., 2018;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
CD71+ Erythroid Suppressor Cells Promote Fetomaternal Tolerance through Arginase-2 and PDL-1
Authors: C Delyea, N Bozorgmehr, P Koleva, G Dunsmore, S Shahbaz, V Huang, S Elahi
J. Immunol., 2018;0(0):.
Species: Mouse
Sample Types: Tissue Homogenates
-
Fraxinellone Attenuates Rheumatoid Inflammation in Mice
Authors: SM Jung, J Lee, SY Baek, J Lee, SG Jang, SM Hong, JS Park, ML Cho, SH Park, SK Kwok
Int J Mol Sci, 2018;19(3):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Stimulation of TNF receptor type 2 expands regulatory T cells and ameliorates established collagen-induced arthritis in mice
Authors: V Lamontain, T Schmid, D Weber-Stef, D Zeller, Z Jenei-Lanz, H Wajant, RH Straub, DN Männel
Cell. Mol. Immunol., 2018;0(0):.
Species: Mouse
Sample Types: Serum
-
Improving therapeutic efficacy of IL-12 intratumoral gene electrotransfer through novel plasmid design and modified parameters
Authors: C Burkart, A Mukhopadhy, SA Shirley, RJ Connolly, JH Wright, A Bahrami, JS Campbell, RH Pierce, DA Canton
Gene Ther., 2018;0(0):.
Species: Mouse
Sample Types: Tissue Homogenates
-
Vaccination with whole-cell killed or recombinant leishmanial protein and toll-like receptor agonists against Leishmania tropica in BALB/c mice
Authors: M Rostamian, F Bahrami, HM Niknam
PLoS ONE, 2018;13(9):e0204491.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Analysis of the Trichuris suis excretory/secretory proteins as a function of life cycle stage and their immunomodulatory properties
Authors: LP Leroux, M Nasr, R Valanparam, M Tam, BA Rosa, E Siciliani, DE Hill, DS Zarlenga, M Jaramillo, JV Weinstock, TG Geary, MM Stevenson, JF Urban, M Mitreva, A Jardim
Sci Rep, 2018;8(1):15921.
Species: Mouse
Sample Types: Cell Culture Supernates
-
The Plant Proteinase Inhibitor CrataBL Plays a Role in Controlling Asthma Response in Mice
Authors: ASS Bortolozzo, APD Rodrigues, FM Arantes-Co, BM Saraiva-Ro, FCR de Souza, TR Brüggemann, MV de Brito, RDS Ferreira, MTDS Correia, PMG Paiva, CM Prado, EA Leick, MLV Oliva, MA Martins, VC Ruiz-Schut, RF Righetti, IFLC Tibério
Biomed Res Int, 2018;2018(0):9274817.
Species: Mouse
Sample Types: Tissue Homogenates
-
Increasing intratumor C/EBP-? LIP and nitric oxide levels overcome resistance to doxorubicin in triple negative breast cancer
Authors: IC Salaroglio, E Gazzano, A Abdullrahm, E Mungo, B Castella, GEFA Abd-Elrahm, M Massaia, M Donadelli, M Rubinstein, C Riganti, J Kopecka
J. Exp. Clin. Cancer Res., 2018;37(1):286.
Species: Mouse
Sample Types: Tissue Homogenates
-
Brief Exposure of Skin to Near-Infrared Laser Modulates Mast Cell Function and Augments the Immune Response
Authors: Y Kimizuka, W Katagiri, JJ Locascio, A Shigeta, Y Sasaki, M Shibata, K Morse, RF Sîrbulescu, M Miyatake, P Reeves, M Suematsu, J Gelfand, T Brauns, MC Poznansky, K Tsukada, S Kashiwagi
J. Immunol., 2018;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
IGF-1-Overexpressing Mesenchymal Stem/Stromal Cells Promote Immunomodulatory and Proregenerative Effects in Chronic Experimental Chagas Disease
Authors: DN Silva, BSF Souza, CM Azevedo, JF Vasconcelo, PG de Jesus, MS Feitoza, CS Meira, GB Carvalho, BR Cavalcante, R Ribeiro-Do, MBP Soares
Stem Cells Int, 2018;2018(0):9108681.
Species: Mouse
Sample Types: Serum
-
PrtA immunization fails to protect against pulmonary and invasive infection by Streptococcus pneumoniae
Authors: CF Hsu, CH Hsiao, SF Tseng, JR Chen, YJ Liao, SJ Chen, CS Lin, HK Sytwu, YP Chuang
Respir. Res., 2018;19(1):187.
Species: Mouse
Sample Types: Cell Culture Supernates
-
A Restricted Role for Fc?R in the Regulation of Adaptive Immunity
Authors: MF Fransen, H Benonisson, WW van Maren, HS Sow, C Breukel, MM Linssen, JWC Claassens, C Brouwers, J van der Ka, M Camps, JW Kleinovink, KK Vonk, S van Heinin, N Klar, L van Beek, V van Harmel, L Daxinger, KS Nandakumar, R Holmdahl, C Coward, Q Lin, S Hirose, D Salvatori, T van Hall, C van Kooten, P Mastroeni, F Ossendorp, JS Verbeek
J. Immunol., 2018;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
ATX-MS-1467 Induces Long-Term Tolerance to Myelin Basic Protein in (DR2?�?Ob1)F1 Mice by Induction of IL-10-Secreting iTregs
Authors: ALS De Souza, S Rudin, R Chang, K Mitchell, T Crandall, S Huang, JK Choi, SL Okitsu, DL Graham, B Tomkinson, T Dellovade
Neurol Ther, 2018;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Respiratory Disease following Viral Lung Infection Alters the Murine Gut Microbiota
Authors: HT Groves, L Cuthbertso, P James, MF Moffatt, MJ Cox, JS Tregoning
Front Immunol, 2018;9(0):182.
Species: Mouse
Sample Types: Airway Lavage Fluid
-
Probiotic treatment during neonatal age provides optimal protection against experimental asthma through the modulation of microbiota and T cells: Neonatal exposure to probiotics prevents asthma
Authors: CFCG Nunes, JS Nogueira, FB Canto, PHO Vianna, BT Ciambarell, PMRE Silva, KR Miranda, LA Lobo, RMCP Domingues, M Busch, GC Atella, AM Vale, M Bellio, A Nóbrega, R Fucs
Int. Immunol., 2018;0(0):.
Species: Mouse
Sample Types: BALF
Applications: ELISA Capture -
Immunization with Pseudomonas aeruginosa outer membrane vesicles stimulates protective immunity in mice
Authors: X Zhang, F Yang, J Zou, W Wu, H Jing, Q Gou, H Li, J Gu, Q Zou, J Zhang
Vaccine, 2018;36(8):1047-1054.
Species: Mouse
Sample Types: Cell Culture Supernates
Applications: ELISA Capture -
Analogous corticosteroids, 9A and EK100, derived from solid-state-cultured mycelium of Antrodia camphorata inhibit proinflammatory cytokine expression in macrophages
Authors: ST Kao, YH Kuo, SD Wang, HJ Hong, LJ Lin
Cytokine, 2018;108(0):136-144.
Species: Mouse
Sample Types: BALF
-
A novel multi-peptide subunit vaccine admixed with AddaVax adjuvant produces significant immunogenicity and protection against Proteus mirabilis urinary tract infection in mice model
Authors: E Choubini, M Habibi, A Khorshidi, A Ghasemi, MR Asadi Kara, S Bouzari
Mol. Immunol., 2018;96(0):88-97.
Species: Mouse
Sample Types: Cell Culture Supernates
Applications: ELISA Standard -
Ethanolic extract of the fungus Trichoderma stromaticum decreases inflammation and ameliorates experimental cerebral malaria in C57BL/6 mice
Authors: Y Cariaco, WR Lima, R Sousa, LAC Nascimento, MP Briceño, WL Fotoran, G Wunderlich, JL Dos Santos, NM Silva
Sci Rep, 2018;8(1):1547.
Species: Mouse
Sample Types: Serum
-
Thymic-Specific Serine Protease Limits Central Tolerance and Exacerbates Experimental Autoimmune Encephalomyelitis
Authors: L Serre, M Girard, A Ramadan, P Menut, N Rouquié, LE Lucca, K Mahiddine, B Leobon, LT Mars, S Guerder
J. Immunol., 2017;0(0):.
Species: Mouse
Sample Types: Cell Lysates
-
Impact of combined sodium chloride and saturated long-chain fatty acid challenge on the differentiation of T helper cells in neuroinflammation
Authors: A Hammer, A Schliep, S Jörg, A Haghikia, R Gold, M Kleinewiet, DN Müller, RA Linker
J Neuroinflammation, 2017;14(1):184.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Chronic Toxoplasma gondii Infection Exacerbates Secondary Polymicrobial Sepsis
Authors: MC Souza, DM Fonseca, A Kanashiro, L Benevides, TS Medina, MS Dias, WA Andrade, G Bonfá, MAB Silva, A Gozzi, MC Borges, RT Gazzinelli, JC Alves-Filh, FQ Cunha, JS Silva
Front Cell Infect Microbiol, 2017;7(0):116.
Species: Mouse
Sample Types: Serum
-
Therapeutic effect of human adipose-derived stem cells and their secretome in experimental diabetic pain
Authors: AT Brini, G Amodeo, LM Ferreira, A Milani, S Niada, G Moschetti, S Franchi, E Borsani, LF Rodella, AE Panerai, P Sacerdote
Sci Rep, 2017;7(1):9904.
Species: Mouse
Sample Types: Tissue Homogenates
-
Th17 cells are refractory to senescence and retain robust antitumor activity after long-term ex vivo expansion
Authors: JS Bowers, MH Nelson, K Majchrzak, SR Bailey, B Rohrer, AD Kaiser, C Atkinson, L Gattinoni, CM Paulos
JCI Insight, 2017;2(5):e90772.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Semiconductor diode laser device adjuvanting intradermal vaccine
Authors: Y Kimizuka, JJ Callahan, Z Huang, K Morse, W Katagiri, A Shigeta, R Bronson, S Takeuchi, Y Shimaoka, MP Chan, Y Zeng, B Li, H Chen, RY Tan, C Dwyer, T Mulley, P Leblanc, C Goudie, J Gelfand, K Tsukada, T Brauns, MC Poznansky, D Bean, S Kashiwagi
Vaccine, 2017;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Erythroid Suppressor Cells Compromise Neonatal Immune Response against Bordetella pertussis
Authors: G Dunsmore, N Bozorgmehr, C Delyea, P Koleva, A Namdar, S Elahi
J. Immunol., 2017;0(0):.
Species: Mouse
Sample Types: Tissue Homogenates
-
IRF5 distinguishes severe asthma in humans and drives Th1 phenotype and airway hyperreactivity in mice
Authors: TB Oriss, M Raundhal, C Morse, RE Huff, S Das, R Hannum, MC Gauthier, KL Scholl, K Chakrabort, SM Nouraie, SE Wenzel, P Ray, A Ray
JCI Insight, 2017;2(10):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Contributions of CD8 T cells to the pathogenesis of mouse adenovirus type 1 respiratory infection
Authors: CT Molloy, JS Andonian, HM Seltzer, MC Procario, ME Watson, JB Weinberg
Virology, 2017;507(0):64-74.
-
Inducing maternal inflammation promotes leptin production in offspring but does not improve allergic symptoms in a mouse model of allergic rhinitis
Authors: A Imai, K Satoi, E Fujimoto, K Sato
Heliyon, 2017;3(6):e00327.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Oncolytic adenovirus and tumor-targeting immune modulatory therapy improve autologous cancer vaccination
Authors: H Jiang, Y Rivera-Mol, K Clise-Dwye, L Bover, L Vence, Y Yuan, FF Lang, C Toniatti, MB Hossain, C Gomez-Manz, J Fueyo
Cancer Res., 2017;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Both anti-TNF and CTLA4 Ig treatments attenuate the disease severity of staphylococcal dermatitis in mice
Authors: M Na, W Wang, Y Fei, E Josefsson, A Ali, T Jin
PLoS ONE, 2017;12(3):e0173492.
Species: Mouse
Sample Types: Tissue Homogenates
-
Hp91 immunoadjuvant: An HMGB1-derived peptide for development of therapeutic HPV vaccines
Authors: Somayeh Talebi
Biomed. Pharmacother, 2017;85(0):148-154.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Natural killer cell-intrinsic type I IFN signaling controls Klebsiella pneumoniae growth during lung infection
Authors: M Ivin, A Dumigan, FN de Vasconc, F Ebner, M Borroni, A Kavirayani, KN Przybyszew, RJ Ingram, S Lienenklau, U Kalinke, D Stoiber, JA Bengoechea, P Kovarik
PLoS Pathog., 2017;13(11):e1006696.
Species: Mouse
Sample Types: Tissue Homogenates
-
Role of NOX2-derived reactive oxygen species in NK cell-mediated control of murine melanoma metastasis
Authors: E Aydin, J Johansson, FH Nazir, K Hellstrand, A Martner
Cancer Immunol Res, 2017;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Synthetic Cannabinoid-Induced Immunosuppression Augments Cerebellar Dysfunction in Tetanus-Toxin Treated Mice
Authors: J Yun, SM Gu, TH Lee, YJ Song, S Seong, YH Kim, HJ Cha, KM Han, J Shin, H Oh, K Jung, C Ahn, HK Park, HS Kim
Biomol Ther (Seoul), 2017;25(3):266-271.
Species: Mouse
Sample Types: Tissue Homogenates
-
Repeated Activation of Lung Invariant NKT Cells Results in Chronic Obstructive Pulmonary Disease-Like Symptoms.
Authors: Tsao C, Tsao P, Chen Y, Chuang Y
PLoS ONE, 2016;11(1):e0147710.
Species: Mouse
Sample Types: BALF
-
Protective and Pathogenic Roles of CD8+ T Lymphocytes in Murine Orientia tsutsugamushi Infection
PLoS Negl Trop Dis, 2016;10(9):e0004991.
Species: Mouse
Sample Types: Serum
-
AAV8-Mediated Angiotensin-Converting Enzyme 2 Gene Delivery Prevents Experimental Autoimmune Uveitis by Regulating MAPK, NF-?B and STAT3 Pathways
Sci Rep, 2016;6(0):31912.
Species: Mouse
Sample Types: Cell Culture Supernates
-
ER? in CD4+ T Cells Is Crucial for Ligand-Mediated Suppression of Central Nervous System Autoimmunity
J Immunol, 2016;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Coadministration of a Plasmid Encoding HIV-1 Gag Enhances the Efficacy of Cancer DNA Vaccines
Mol Ther, 2016;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Proinflammatory M1 macrophages inhibit RANKL-induced osteoclastogenesis
Infect Immun, 2016;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
C1P Attenuates Lipopolysaccharide-Induced Acute Lung Injury by Preventing NF-?B Activation in Neutrophils
J Immunol, 2016;196(5):2319-26.
Species: Mouse
Sample Types: BALF
-
Lack of IL-1 Receptor-Associated Kinase-4 Leads to Defective Th1 Cell Responses and Renders Mice Susceptible to Mycobacterial Infection
J Immunol, 2016;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Advax, a Delta Inulin Microparticle, Potentiates In-built Adjuvant Property of Co-administered Vaccines
EBioMedicine, 2016;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
IL-22 Restrains Tapeworm-Mediated Protection against Experimental Colitis via Regulation of IL-25 Expression
Authors: JL Reyes, MR Fernando, F Lopes, G Leung, NL Mancini, CE Matisz, A Wang, DM McKay
PLoS Pathog, 2016;12(4):e1005481.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Novel Function of Extracellular Matrix Protein 1 in Suppressing Th17 Cell Development in Experimental Autoimmune Encephalomyelitis
Authors: Pan Su
J Immunol, 2016;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Dysfunction of hepatic regulatory T cells in experimental sclerosing cholangitis is related with IL-12 signaling
Authors: Dorothee Schwinge
J. Hepatol, 2016;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Myelin Oligodendrocyte Glycoprotein induces incomplete tolerance of CD4(+) T cells specific for both a myelin and a neuronal self antigen in mice
Authors: Liliana E Lucca
Eur J Immunol, 2016;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Mucosal immunization confers long-term protection against intragastrically established Neospora caninum infection
Vaccine, 2016;0(0):.
Species: Mouse
Sample Types: Tissue Homogenates
-
Interleukin-27 Mediates Susceptibility to Visceral Leishmaniasis by Suppressing the IL-17-Neutrophil Response
Authors: Gustavo F S Quirino
Infect Immun, 2016;0(0):.
Species: Mouse
Sample Types: Tissue Homogenates
-
Impact of Histone H1 on the Progression of Allergic Rhinitis and Its Suppression by Neutralizing Antibody in Mice
Authors: T Nakano, R Kamei, T Fujimura, Y Takaoka, A Hori, CY Lai, KC Chiang, Y Shimada, N Ohmori, T Goto, K Ono, CL Chen, S Goto, S Kawamoto
PLoS ONE, 2016;11(4):e0153630.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Immune signatures of protective spleen memory CD8 T cells
Sci Rep, 2016;6(0):37651.
Species: Mouse
Sample Types: Cell Culture Supernates
-
IL-22 dampens the T cell response in experimental malaria
Authors: Julie Sellau
Sci Rep, 2016;6(0):28058.
Species: Mouse
Sample Types: Cell Culture Supernates
-
The Hippo Pathway Kinases LATS1/2 Suppress Cancer Immunity
Authors: Toshiro Moroishi
Cell, 2016;167(6):1525-1539.e17.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Gene Therapy Induces Antigen-Specific Tolerance in Experimental Collagen-Induced Arthritis
PLoS ONE, 2016;11(5):e0154630.
Species: Mouse
Sample Types: Cell Culture Supernates
-
MyD88 adapter-like (Mal)/TIRAP is required for cytokine production by splenic Ly6CloTLR2hi but not by Ly6ChiTLR2hi monocytes during Trypanosoma cruzi Infection
J Biol Chem, 2016;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Eriobotrya japonica Water Extract Characterization: An Inducer of Interferon-Gamma Production Mainly by the JAK-STAT Pathway
Authors: Khalid Z Matalka
Molecules, 2016;21(6):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Testosterone-Mediated Endocrine Function and TH1/TH2 Cytokine Balance after Prenatal Exposure to Perfluorooctane Sulfonate: By Sex Status
Int J Mol Sci, 2016;17(9):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Involvement of IL-17A-producing TCR ?? T cells in late protective immunity against pulmonary Mycobacterium tuberculosis infection
Authors: Masayuki Umemura
Immun Inflamm Dis, 2016;4(4):401-412.
Species: Mouse
Sample Types: Tissue Homogenates
-
Cannabinoid receptor 2 modulates susceptibility to experimental cerebral malaria through a CCL17-dependent mechanism
J Biol Chem, 2016;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Prolonged contact with dendritic cells turns lymph node-resident NK cells into anti-tumor effectors
EMBO Mol Med, 2016;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Poly-N-acetyl glucosamine production by Staphylococcus epidermidis cells increases their in vivo pro-inflammatory effect
Infect Immun, 2016;0(0):.
Species: Mouse
Sample Types: Tissue Secretion
-
The circadian clock regulates inflammatory arthritis
FASEB J, 2016;0(0):.
Species: Mouse
Sample Types: Serum
-
A Simple Screening Approach To Prioritize Genes for Functional Analysis Identifies a Role for Interferon Regulatory Factor 7 in the Control of Respiratory Syncytial Virus Disease
Authors: John S Tregoning
mSystems, 2016;1(3):.
Species: Mouse
Sample Types: Tissue Homogenates
-
Dendritic Cell-Like Cells Accumulate in Regenerating Murine Skeletal Muscle after Injury and Boost Adaptive Immune Responses Only upon a Microbial Challenge
PLoS ONE, 2016;11(5):e0155870.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Gene electrotransfer into skin using noninvasive multi-electrode array for vaccination and wound healing
Authors: Spela Kos
Bioelectrochemistry, 2016;114(0):33-41.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Editor's Highlight: Subvisible Aggregates of Immunogenic Proteins Promote a Th1-Type Response
Authors: Jeremy P Derrick
Toxicol. Sci., 2016;153(2):258-70.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Chrysin promotes attenuation of depressive-like behavior and hippocampal dysfunction resulting from olfactory bulbectomy in mice
Authors: Silvana Peterini Boeira
Chem. Biol. Interact., 2016;0(0):.
Species: Mouse
Sample Types: Tissue Homogenates
-
NLRP12 negatively regulates proinflammatory cytokine production and host defense against Brucella abortus
Eur. J. Immunol., 2016;0(0):.
Species: Mouse
Sample Types: Serum
-
IL-27 Is Essential for Suppression of Experimental Allergic Asthma by the TLR7/8 Agonist R848 (Resiquimod)
Authors: Gesine Hansen
J. Immunol., 2016;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Comparison of potential protection conferred by three immunization strategies (protein/protein, DNA/DNA, and DNA/protein) against Brucella infection using Omp2b in BALB/c Mice
Authors: Saeid Bouzari
Vet. Microbiol., 2016;197(0):47-52.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Tuberculosis Susceptibility and Vaccine Protection Are Independently Controlled by Host Genotype
MBio, 2016;7(5):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
T-bet overexpression regulates AHR-mediated Th-17 differentiation through an IFN?-independent pathway
Authors: Masahiro Yokosawa
Clin. Exp. Immunol, 2016;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
DCIR maintains bone homeostasis by regulating IFN-gamma production in T cells.
Authors: Maruhashi T, Kaifu T, Yabe R, Seno A, Chung S, Fujikado N, Iwakura Y
J Immunol, 2015;194(12):5681-91.
Species: Mouse
Sample Types: Tissue Homogenates
-
Intestinal helminths regulate lethal acute graft-versus-host disease and preserve the graft-versus-tumor effect in mice.
Authors: Li Y, Chen H, Bannick N, Henry M, Holm A, Metwali A, Urban J, Rothman P, Weiner G, Blazar B, Elliott D, Ince M
J Immunol, 2015;194(3):1011-20.
Species: Mouse
Sample Types: Cell Culture Supernates
-
NK cells require IL-28R for optimal in vivo activity.
Authors: Souza-Fonseca-Guimaraes F, Young A, Mittal D, Martinet L, Bruedigam C, Takeda K, Andoniou C, Degli-Esposti M, Hill G, Smyth M
Proc Natl Acad Sci U S A, 2015;112(18):E2376-84.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Limited Contribution of IL-36 versus IL-1 and TNF Pathways in Host Response to Mycobacterial Infection.
Authors: Segueni N, Vigne S, Palmer G, Bourigault M, Olleros M, Vesin D, Garcia I, Ryffel B, Quesniaux V, Gabay C
PLoS ONE, 2015;10(5):e0126058.
Species: Mouse
Sample Types: Tissue Homogenates
-
CD252 regulates mast cell mediated, CD1d-restricted NKT-cell activation in mice.
Authors: Gonzalez Roldan N, Orinska Z, Ewers H, Bulfone-Paus S
Eur J Immunol, 2015;46(2):432-9.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Proinflammatory effects of interferon gamma in mouse adenovirus 1 myocarditis.
Authors: McCarthy M, Procario M, Twisselmann N, Wilkinson J, Archambeau A, Michele D, Day S, Weinberg J
J Virol, 2015;89(1):468-79.
Species: Mouse
Sample Types: Tissue Homogenates
-
B cells modulate systemic responses to Pneumocystis murina lung infection and protect on-demand hematopoiesis via T cell-independent innate mechanisms when type I interferon signaling is absent.
Authors: Hoyt T, Dobrinen E, Kochetkova I, Meissner N
Infect Immun, 2015;83(2):743-58.
Species: Mouse
Sample Types: Serum
-
High IFN-gamma and low SLPI mark severe asthma in mice and humans.
Authors: Raundhal M, Morse C, Khare A, Oriss T, Milosevic J, Trudeau J, Huff R, Pilewski J, Holguin F, Kolls J, Wenzel S, Ray P, Ray A
J Clin Invest, 2015;125(8):3037-50.
Species: Mouse
Sample Types: Tissue Homogenates
-
Phosphatidylinositol 3-Kinase gamma is required for the development of experimental cerebral malaria.
Authors: Lacerda-Queiroz N, Brant F, Rodrigues D, Vago J, Rachid M, Sousa L, Teixeira M, Teixeira A
PLoS ONE, 2015;10(3):e0119633.
Species: Mouse
Sample Types: Serum
-
Histone deacetylase 11: A novel epigenetic regulator of myeloid derived suppressor cell expansion and function.
Authors: Sahakian E, Powers J, Chen J, Deng S, Cheng F, Distler A, Woods D, Rock-Klotz J, Sodre A, Youn J, Woan K, Villagra A, Gabrilovich D, Sotomayor E, Pinilla-Ibarz J
Mol Immunol, 2015;63(2):579-85.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Testosterone suppresses hepatic inflammation by the downregulation of IL-17, CXCL-9, and CXCL-10 in a mouse model of experimental acute cholangitis.
Authors: Schwinge D, Carambia A, Quaas A, Krech T, Wegscheid C, Tiegs G, Prinz I, Lohse A, Herkel J, Schramm C
J Immunol, 2015;194(6):2522-30.
-
Murid Gammaherpesvirus Latency-Associated Protein M2 Promotes the Formation of Conjugates between Transformed B Lymphoma Cells and T Helper Cells.
Authors: Fontinha D, Lopes F, Marques S, Simas J
PLoS ONE, 2015;10(11):e0142540.
Species: Mouse
Sample Types: Cell Culture Supernates
-
A critical role for the TLR signaling adapter Mal in alveolar macrophage-mediated protection against Bordetella pertussis.
Authors: Bernard N, Finlay C, Tannahill G, Cassidy J, O'Neill L, Mills K
Mucosal Immunol, 2015;8(5):982-92.
Species: Mouse
Sample Types: Tissue Homogenates
-
Memory Th1 Cells Are Protective in Invasive Staphylococcus aureus Infection.
Authors: Brown A, Murphy A, Lalor S, Leech J, O'Keeffe K, Mac Aogain M, O'Halloran D, Lacey K, Tavakol M, Hearnden C, Fitzgerald-Hughes D, Humphreys H, Fennell J, van Wamel W, Foster T, Geoghegan J, Lavelle E, Rogers T, McLoughlin R
PLoS Pathog, 2015;11(11):e1005226.
Species: Mouse
Sample Types: Cell Culture Supernates
-
TAGLN2 regulates T cell activation by stabilizing the actin cytoskeleton at the immunological synapse.
Authors: Na B, Kim H, Piragyte I, Oh H, Kwon M, Akber U, Lee H, Park D, Song W, Park Z, Im S, Rho M, Hyun Y, Kim M, Jun C
J Cell Biol, 2015;209(1):143-62.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Hydroxypropyl-beta-cyclodextrin spikes local inflammation that induces Th2 cell and T follicular helper cell responses to the coadministered antigen.
Authors: Onishi M, Ozasa K, Kobiyama K, Ohata K, Kitano M, Taniguchi K, Homma T, Kobayashi M, Sato A, Katakai Y, Yasutomi Y, Wijaya E, Igarashi Y, Nakatsu N, Ise W, Inoue T, Yamada H, Vandenbon A, Standley D, Kurosaki T, Coban C, Aoshi T, Kuroda E, Ishii K
J Immunol, 2015;194(6):2673-82.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Th1-Like ICOS+ Foxp3+ Treg Cells Preferentially Express CXCR3 and Home to beta-Islets during Pre-Diabetes in BDC2.5 NOD Mice.
Authors: Kornete M, Mason E, Girouard J, Lafferty E, Qureshi S, Piccirillo C
PLoS ONE, 2015;10(5):e0126311.
Species: Mouse
Sample Types: Tissue Homogenates
-
Overexpression of IL-15 promotes tumor destruction via NK1.1+ cells in a spontaneous breast cancer model.
Authors: Gillgrass A, Chew M, Krneta T, Ashkar A
BMC Cancer, 2015;15(0):293.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Effects of High-Intensity Swimming on Lung Inflammation and Oxidative Stress in a Murine Model of DEP-Induced Injury.
Authors: Avila L, Bruggemann T, Bobinski F, da Silva M, Oliveira R, Martins D, Mazzardo-Martins L, Duarte M, de Souza L, Dafre A, Vieira R, Santos A, Bonorino K, Hizume Kunzler D
PLoS ONE, 2015;10(9):e0137273.
Species: Mouse
Sample Types: Tissue Homogenates
-
Immune requirements for protective Th17 recall responses to Mycobacterium tuberculosis challenge.
Authors: Monin L, Griffiths K, Slight S, Lin Y, Rangel-Moreno J, Khader S
Mucosal Immunol, 2015;8(5):1099-109.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Mesenchymal stem/stromal cells protect against autoimmunity via CCL2-dependent recruitment of myeloid-derived suppressor cells.
Authors: Lee H, Ko J, Jeong H, Ko A, Kim M, Wee W, Yoon S, Oh J
J Immunol, 2015;194(8):3634-45.
Species: Mouse
Sample Types: Tissue Homogenates
-
Critical role of IL-33 receptor ST2 in experimental cerebral malaria development.
Authors: Palomo J, Reverchon F, Piotet J, Besnard A, Couturier-Maillard A, Maillet I, Tefit M, Erard F, Mazier D, Ryffel B, Quesniaux V
Eur J Immunol, 2015;45(5):1354-65.
-
EBV oncogene N-LMP1 induces CD4 T cell-mediated angiogenic blockade in the murine tumor model.
Authors: Wu T, Wang L, Liu S, Hsu T, Lin C, Feng G, Chen J, Liu H, Chung I, Yen T, Chang Y, Liao S, Chang C, Chow K
J Immunol, 2015;194(9):4577-87.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Innate immunity drives the initiation of a murine model of primary biliary cirrhosis.
Authors: Chang C, Chen Y, Zhang W, Leung P, Gershwin M, Chuang Y
PLoS ONE, 2015;10(3):e0121320.
Species: Mouse
Sample Types: Serum
-
Simultaneous and dose dependent melanoma cytotoxic and immune stimulatory activity of betulin.
Authors: Pfarr K, Danciu C, Arlt O, Neske C, Dehelean C, Pfeilschifter J, Radeke H
PLoS ONE, 2015;10(3):e0118802.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Superior Suppressive Capacity of Skin Tregs Compared with Lung Tregs in a Model of Epicutaneous Priming.
Authors: Mahapatra S, Albrecht M, Baru A, Sparwasser T, Herrick C, Dittrich A
J Invest Dermatol, 2015;135(10):2418-26.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Mutant Brucella abortus membrane fusogenic protein induces protection against challenge infection in mice.
Authors: de Souza Filho J, de Paulo Martins V, Campos P, Alves-Silva J, Santos N, de Oliveira F, Menezes G, Azevedo V, Cravero S, Oliveira S
Infect Immun, 2015;83(4):1458-64.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Differential Immunometabolic Phenotype in Th1 and Th2 Dominant Mouse Strains in Response to High-Fat Feeding.
Authors: Jovicic N, Jeftic I, Jovanovic I, Radosavljevic G, Arsenijevic N, Lukic M, Pejnovic N
PLoS ONE, 2015;10(7):e0134089.
Species: Mouse
Sample Types: Tissue Homogenates
-
IFN-gamma-producing and IL-17-producing gammadelta T cells differentiate at distinct developmental stages in murine fetal thymus.
Authors: Shibata K, Yamada H, Nakamura M, Hatano S, Katsuragi Y, Kominami R, Yoshikai Y
J Immunol, 2014;192(5):2210-8.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Signaling via tumor necrosis factor receptor 1 but not Toll-like receptor 2 contributes significantly to hydrosalpinx development following Chlamydia muridarum infection.
Authors: Dong X, Liu Y, Chang X, Lei L, Zhong G
Infect Immun, 2014;82(5):1833-9.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Defining immune engagement thresholds for in vivo control of virus-driven lymphoproliferation.
Authors: Godinho-Silva C, Marques S, Fontinha D, Veiga-Fernandes H, Stevenson P, Simas J
PLoS Pathog, 2014;10(6):e1004220.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Lifetime-dependent effects of bisphenol A on asthma development in an experimental mouse model.
Authors: Petzold, Susanne, Averbeck, Marco, Simon, Jan C, Lehmann, Irina, Polte, Tobias
PLoS ONE, 2014;9(6):e100468.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Animal model of respiratory syncytial virus: CD8+ T cells cause a cytokine storm that is chemically tractable by sphingosine-1-phosphate 1 receptor agonist therapy.
Authors: Walsh K, Teijaro J, Brock L, Fremgen D, Collins P, Rosen H, Oldstone M
J Virol, 2014;88(11):6281-93.
Species: Mouse
Sample Types: BALF
-
Differential role of NK cells against Candida albicans infection in immunocompetent or immunocompromised mice.
Authors: Quintin J, Voigt J, van der Voort R, Jacobsen I, Verschueren I, Hube B, Giamarellos-Bourboulis E, van der Meer J, Joosten L, Kurzai O, Netea M
Eur J Immunol, 2014;44(8):2405-14.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Delineating the role of histamine-1- and -4-receptors in a mouse model of Th2-dependent antigen-specific skin inflammation.
Authors: Mahapatra S, Albrecht M, Behrens B, Jirmo A, Behrens G, Hartwig C, Neumann D, Raap U, Bahre H, Herrick C, Dittrich A
PLoS ONE, 2014;9(2):e87296.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Differential IL-10 production by DCs determines the distinct adjuvant effects of LPS and PTX in EAE induction.
Authors: Zhou H, Wang Y, Lian Q, Yang B, Ma Y, Wu X, Sun S, Liu Y, Sun B
Eur J Immunol, 2014;44(5):1352-62.
Species: Mouse
Sample Types: Cell Culture Supernates
-
IL-17 contributes to neutrophil recruitment but not to control of viral replication during acute mouse adenovirus type 1 respiratory infection.
Authors: McCarthy M, Zhu L, Procario M, Weinberg J
Virology, 2014;456(0):259-67.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Dichloroacetate modulates cytokines toward T helper 1 function via induction of the interleukin-12-interferon-gamma pathway.
Authors: Badr M, Qinna N, Qadan F, Matalka K
Onco Targets Ther, 2014;7(0):193-201.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) prevents lipopolysaccharide (LPS)-induced, sepsis-related severe acute lung injury in mice.
Authors: Takaoka, Yuki, Goto, Shigeru, Nakano, Toshiaki, Tseng, Hui-Peng, Yang, Shih-Min, Kawamoto, Seiji, Ono, Kazuhisa, Chen, Chao-Lon
Sci Rep, 2014;4(0):5204.
Species: Mouse
Sample Types: Serum
-
Malaria-induced NLRP12/NLRP3-dependent caspase-1 activation mediates inflammation and hypersensitivity to bacterial superinfection.
Authors: Ataide M, Andrade W, Zamboni D, Wang D, Souza M, Franklin B, Elian S, Martins F, Pereira D, Reed G, Fitzgerald K, Golenbock D, Gazzinelli R
PLoS Pathog, 2014;10(1):e1003885.
Species: Mouse
Sample Types: Whole Blood
-
STAT4 deficiency fails to induce lung Th2 or Th17 immunity following primary or secondary respiratory syncytial virus (RSV) challenge but enhances the lung RSV-specific CD8+ T cell immune response to secondary challenge.
Authors: Dulek D, Newcomb D, Toki S, Goliniewska K, Cephus J, Reiss S, Bates J, Crowe J, Boyd K, Moore M, Zhou W, Peebles R
J Virol, 2014;88(17):9655-72.
Species: Mouse
Sample Types: Tissue Homogenates
-
The glycosylated Rv1860 protein of mycobacterium tuberculosis inhibits dendritic cell mediated TH1 and TH17 polarization of T cells and abrogates protective immunity conferred by BCG.
Authors: Satchidanandam V, Kumar N, Jumani R, Challu V, Elangovan S, Khan N
PLoS Pathog, 2014;10(6):e1004176.
Species: Mouse
Sample Types: Cell Culture Supernates
-
MyD88 signalling in myeloid cells is sufficient to prevent chronic mycobacterial infection.
Authors: Berod L, Stuve P, Swallow M, Arnold-Schrauf C, Kruse F, Gentilini M, Freitag J, Holzmann B, Sparwasser T
Eur J Immunol, 2014;44(5):1399-409.
Species: Mouse
Sample Types: Serum
-
Unique macrophages different from M1/M2 macrophages inhibit T cell mitogenesis while upregulating Th17 polarization.
Authors: Tatano Y, Shimizu T, Tomioka H
Sci Rep, 2014;4(0):4146.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Pulmonary immune responses to 2009 pandemic influenza A (H1N1) virus in mice.
Authors: Lv J, Wang D, Hua Y, Pei S, Wang J, Hu W, Wang X, Jia N, Jiang Q
BMC Infect Dis, 2014;14(0):197.
Species: Mouse
Sample Types: Tissue Homogenates
-
Role of the aryl hydrocarbon receptor in the immune response profile and development of pathology during Plasmodium berghei Anka infection.
Authors: Brant F, Miranda A, Esper L, Rodrigues D, Kangussu L, Bonaventura D, Soriani F, Pinho V, Souza D, Rachid M, Weiss L, Tanowitz H, Teixeira M, Teixeira A, Machado F
Infect Immun, 2014;82(8):3127-40.
Species: Mouse
Sample Types: Tissue Homogenates
-
An iron-acquisition-deficient mutant of Corynebacterium pseudotuberculosis efficiently protects mice against challenge.
Authors: Ribeiro D, Rocha F, Leite K, Soares S, Silva A, Portela R, Meyer R, Miyoshi A, Oliveira S, Azevedo V, Dorella F
Vet Res, 2014;45(0):28.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Intraperitoneal prophylaxis with CpG oligodeoxynucleotides protects neutropenic mice against intracerebral Escherichia coli K1 infection.
Authors: Ribes S, Meister T, Ott M, Redlich S, Janova H, Hanisch U, Nessler S, Nau R
J Neuroinflammation, 2014;11(0):14.
-
IL-25 and type 2 innate lymphoid cells induce pulmonary fibrosis.
Authors: Hams, Emily, Armstrong, Michelle, Barlow, Jillian, Saunders, Sean P, Schwartz, Christia, Cooke, Gordon, Fahy, Ruairi J, Crotty, Thomas B, Hirani, Nikhil, Flynn, Robin J, Voehringer, David, McKenzie, Andrew N, Donnelly, Seamas C, Fallon, Padraic
Proc Natl Acad Sci U S A, 2014;111(1):367-72.
Species: Mouse
Sample Types: Tissue Homogenates
-
Mapping the innate signaling cascade essential for cytokine storm during influenza virus infection.
Authors: Teijaro J, Walsh K, Rice S, Rosen H, Oldstone M
Proc Natl Acad Sci U S A, 2014;111(10):3799-804.
Species: Mouse
Sample Types: BALF
-
Fingolimod attenuates splenocyte-induced demyelination in cerebellar slice cultures.
Authors: Pritchard A, Mir A, Dev K
PLoS ONE, 2014;9(6):e99444.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Sm10.3, a member of the micro-exon gene 4 (MEG-4) family, induces erythrocyte agglutination in vitro and partially protects vaccinated mice against Schistosoma mansoni infection.
Authors: Martins V, Morais S, Pinheiro C, Assis N, Figueiredo B, Ricci N, Alves-Silva J, Caliari M, Oliveira S
PLoS Negl Trop Dis, 2014;8(3):e2750.
Species: Mouse
Sample Types: Cell Culture Supernates
-
The aryl hydrocarbon receptor: differential contribution to T helper 17 and T cytotoxic 17 cell development.
Authors: Hayes M, Ovcinnikovs V, Smith A, Kimber I, Dearman R
PLoS ONE, 2014;9(9):e106955.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Protease-activated receptor-2 activation contributes to house dust mite-induced IgE responses in mice.
Authors: Post, Sijranke, Heijink, Irene H, Petersen, Arjen H, de Bruin, Harold G, van Oosterhout, Antoon J, Nawijn, Martijn
PLoS ONE, 2014;9(3):e91206.
Species: Mouse
Sample Types: Tissue Homogenates
-
A2B adenosine receptors prevent insulin resistance by inhibiting adipose tissue inflammation via maintaining alternative macrophage activation.
Authors: Csoka B, Koscso B, Toro G, Kokai E, Virag L, Nemeth Z, Pacher P, Bai P, Hasko G
Diabetes, 2014;63(3):850-66.
Species: Mouse
Sample Types: Plasma
-
IL-27 and IL-12 oppose pro-inflammatory IL-23 in CD4+ T cells by inducing Blimp1.
Authors: Heinemann C, Heink S, Petermann F, Vasanthakumar A, Rothhammer V, Doorduijn E, Mitsdoerffer M, Sie C, Prazeres da Costa O, Buch T, Hemmer B, Oukka M, Kallies A, Korn T
Nat Commun, 2014;5(0):3770.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Recombinant p35 from bacteria can form Interleukin (IL-)12, but Not IL-35.
Authors: Aparicio-Siegmund S, Moll J, Lokau J, Grusdat M, Schroder J, Plohn S, Rose-John S, Grotzinger J, Lang P, Scheller J, Garbers C
PLoS ONE, 2014;9(9):e107990.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Role of OGR1 in myeloid-derived cells in prostate cancer.
Authors: Yan, L, Singh, L S, Zhang, L, Xu, Y
Oncogene, 2014;33(2):157-64.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Protective effect of intranasal immunization with Neospora caninum membrane antigens against murine neosporosis established through the gastrointestinal tract.
Authors: Ferreirinha P, Dias J, Correia A, Perez-Cabezas B, Santos C, Teixeira L, Ribeiro A, Rocha A, Vilanova M
Immunology, 2014;141(2):256-67.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Toll-like receptor 6 senses Mycobacterium avium and is required for efficient control of mycobacterial infection.
Authors: Marinho F, de Paula R, Mendes A, de Almeida L, Gomes M, Carvalho N, Oliveira F, Caliari M, Oliveira S
Eur J Immunol, 2013;43(9):2373-85.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Defining the range of pathogens susceptible to Ifitm3 restriction using a knockout mouse model.
Authors: Everitt, Aaron R, Clare, Simon, McDonald, Jacqueli, Kane, Leanne, Harcourt, Katherin, Ahras, Malika, Lall, Amar, Hale, Christin, Rodgers, Angela, Young, Douglas, Haque, Ashraful, Billker, Oliver, Tregoning, John S, Dougan, Gordon, Kellam, Paul
PLoS ONE, 2013;8(11):e80723.
Species: Mouse
Sample Types: BALF
-
Nanogel-based PspA intranasal vaccine prevents invasive disease and nasal colonization by Streptococcus pneumoniae.
Authors: Kong, Il Gyu, Sato, Ayuko, Yuki, Yoshikaz, Nochi, Tomonori, Takahashi, Haruko, Sawada, Shinichi, Mejima, Mio, Kurokawa, Shiho, Okada, Kazunari, Sato, Shintaro, Briles, David E, Kunisawa, Jun, Inoue, Yusuke, Yamamoto, Masafumi, Akiyoshi, Kazunari, Kiyono, Hiroshi
Infect Immun, 2013;81(5):1625-34.
Species: Mouse
Sample Types: Cell Culture Supernates
-
CD3(-)NK1.1(+) cells aid in the early induction of a Th1 response to an attaching and effacing enteric pathogen.
Authors: Reid-Yu S, Small C, Coombes B
Eur J Immunol, 2013;43(10):2638-49.
Species: Mouse
Sample Types: Tissue Homogenates
-
Vaccination using recombinants influenza and adenoviruses encoding amastigote surface protein-2 are highly effective on protection against Trypanosoma cruzi infection.
Authors: Barbosa R, Filho B, Dos Santos L, Junior P, Marques P, Pereira R, Cara D, Bruna-Romero O, Rodrigues M, Gazzinelli R, Machado A
PLoS ONE, 2013;8(4):e61795.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Excitotoxic neuronal cell death during an oligodendrocyte-directed CD8+ T cell attack in the CNS gray matter.
Authors: Melzer N, Hicking G, Bittner S, Bobak N, Gobel K, Herrmann A, Wiendl H, Meuth S
J Neuroinflammation, 2013;10(0):121.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Epithelial NF-kappaB orchestrates house dust mite-induced airway inflammation, hyperresponsiveness, and fibrotic remodeling.
Authors: Tully J, Hoffman S, Lahue K, Nolin J, Anathy V, Lundblad L, Daphtary N, Aliyeva M, Black K, Dixon A, Poynter M, Irvin C, Janssen-Heininger Y
J Immunol, 2013;191(12):5811-21.
Species: Mouse
Sample Types: Tissue Homogenates
-
Exposure to atmospheric particulate matter enhances Th17 polarization through the aryl hydrocarbon receptor.
Authors: van Voorhis, Michael, Knopp, Samantha, Julliard, Walker, Fechner, John H, Zhang, Xiaoji, Schauer, James J, Mezrich, Joshua D
PLoS ONE, 2013;8(12):e82545.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Effects of Lactobacillus kefiranofaciens M1 isolated from kefir grains on germ-free mice.
Authors: Chen Y, Chen M
PLoS ONE, 2013;8(11):e78789.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Subcomponent vaccine based on CTA1-DD adjuvant with incorporated UreB class II peptides stimulates protective Helicobacter pylori immunity.
Authors: Nedrud J, Bagheri N, Schon K, Xin W, Bergroth H, Eliasson D, Lycke N
PLoS ONE, 2013;8(12):e83321.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Mesenchymal stem cells inhibit cutaneous radiation-induced fibrosis by suppressing chronic inflammation.
Authors: Horton J, Hudak K, Chung E, White A, Scroggins B, Burkeen J, Citrin D
Stem Cells, 2013;31(10):2231-41.
Species: Mouse
Sample Types: Tissue Homogenates
-
CXCR5(+) T helper cells mediate protective immunity against tuberculosis.
Authors: Slight S, Rangel-Moreno J, Gopal R, Lin Y, Fallert Junecko B, Mehra S, Selman M, Becerril-Villanueva E, Baquera-Heredia J, Pavon L, Kaushal D, Reinhart T, Randall T, Khader S
J Clin Invest, 2013;123(2):712-26.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Genetic deletion of the HIF-1alpha isoform I.1 in T cells enhances antibacterial immunity and improves survival in a murine peritonitis model.
Authors: Georgiev P, Belikoff B, Hatfield S, Ohta A, Sitkovsky M, Lukashev D
Eur J Immunol, 2013;43(3):655-66.
Species: Mouse
Sample Types: Serum
-
Continuous and discontinuous cigarette smoke exposure differentially affects protective Th1 immunity against pulmonary tuberculosis.
Authors: Shaler C, Horvath C, McCormick S, Jeyanathan M, Khera A, Zganiacz A, Kasinska J, Stampfli M, Xing Z
PLoS ONE, 2013;8(3):e59185.
-
Rac2-deficiency leads to exacerbated and protracted colitis in response to Citrobacter rodentium infection.
Authors: Fattouh R, Guo C, Lam G, Gareau M, Ngan B, Glogauer M, Muise A, Brumell J
PLoS ONE, 2013;8(4):e61629.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Bifidobacterium longum alleviates dextran sulfate sodium-induced colitis by suppressing IL-17A response: involvement of intestinal epithelial costimulatory molecules.
Authors: Miyauchi, Eiji, Ogita, Tasuku, Miyamoto, Junki, Kawamoto, Seiji, Morita, Hidetosh, Ohno, Hiroshi, Suzuki, Takuya, Tanabe, Soichi
PLoS ONE, 2013;8(11):e79735.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Critical role of ASC inflammasomes and bacterial type IV secretion system in caspase-1 activation and host innate resistance to Brucella abortus infection.
Authors: Gomes M, Campos P, Oliveira F, Corsetti P, Bortoluci K, Cunha L, Zamboni D, Oliveira S
J Immunol, 2013;190(7):3629-38.
Species: Mouse
Sample Types: Serum
-
UNC93B1 and nucleic acid-sensing Toll-like receptors mediate host resistance to infection with Leishmania major.
Authors: Schamber-Reis B, Petritus P, Caetano B, Martinez E, Okuda K, Golenbock D, Scott P, Gazzinelli R
J Biol Chem, 2013;288(10):7127-36.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Mouse tumor vasculature expresses NKG2D ligands and can be targeted by chimeric NKG2D-modified T cells.
Authors: Zhang T, Sentman C
J Immunol, 2013;190(5):2455-63.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Intravenous mesenchymal stem cells prevented rejection of allogeneic corneal transplants by aborting the early inflammatory response.
Authors: Oh J, Lee R, Yu J, Ko J, Lee H, Ko A, Roddy G, Prockop D
Mol Ther, 2012;20(11):2143-52.
Species: Mouse
Sample Types: Tissue Homogenates
-
Depletion of phagocytic myeloid cells triggers spontaneous T cell- and NK cell-dependent antitumor activity.
Authors: Guth A, Hafeman S, Dow S
Oncoimmunology, 2012;1(8):1248-1257.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Schistosome-derived omega-1 drives Th2 polarization by suppressing protein synthesis following internalization by the mannose receptor.
J. Exp. Med., 2012;209(10):1753-67, S1.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Role of Toll interleukin-1 receptor (IL-1R) 8, a negative regulator of IL-1R/Toll-like receptor signaling, in resistance to acute Pseudomonas aeruginosa lung infection.
Authors: Veliz Rodriguez T, Moalli F, Polentarutti N, Paroni M, Bonavita E, Anselmo A, Nebuloni M, Mantero S, Jaillon S, Bragonzi A, Mantovani A, Riva F, Garlanda C
Infect. Immun., 2012;80(1):100-9.
Species: Mouse
Sample Types: Serum
-
Immune Modulation Mediated by Cryptococcal Laccase Promotes Pulmonary Growth and Brain Dissemination of Virulent Cryptococcus neoformans in Mice.
Authors: Qiu Y, Davis M, Dayrit J, Hadd Z, Meister D, Osterholzer J, Williamson P, Olszewski M
PLoS ONE, 2012;7(10):e47853.
Species: Mouse
Sample Types: Cell Culture Supernates
-
IL-10 mediated regulation of liver inflammation during acute murine cytomegalovirus infection.
Authors: Gaddi, Pamela J, Crane, Meredith, Kamanaka, Masahito, Flavell, Richard, Yap, George S, Salazar-Mather, Thais P
PLoS ONE, 2012;7(8):e42850.
Species: Mouse
Sample Types: Serum
-
TLR9 and MyD88 are crucial for the development of protective immunity to malaria.
Authors: Gowda NM, Wu X, Gowda DC
J. Immunol., 2012;188(10):5073-85.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Control of allergen-induced inflammation and hyperresponsiveness by the metalloproteinase ADAMTS-12.
Authors: Paulissen G, El Hour M, Rocks N, Gueders M, Bureau F, Foidart J, Lopez-Otin C, Noel A, Cataldo D
J Immunol, 2012;189(8):4135-43.
Species: Mouse
Sample Types: Tissue Homogenates
-
Alveolar Macrophages Play a Key Role in Cockroach-Induced Allergic Inflammation via TNF-alpha Pathway.
Authors: Kim J, Sohn J, Choi J, Lee J, Hong C, Lee J, Park J
PLoS ONE, 2012;7(10):e47971.
Species: Mouse
Sample Types: Tissue Homogenates
-
Intestinal epithelial cell-derived semaphorin 7A negatively regulates development of colitis via alphavbeta1 integrin.
Authors: Kang S, Okuno T, Takegahara N, Takamatsu H, Nojima S, Kimura T, Yoshida Y, Ito D, Ohmae S, You DJ, Toyofuku T, Jang MH, Kumanogoh A
J. Immunol., 2011;188(3):1108-16.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Transcriptomic analysis of host immune and cell death responses associated with the influenza A virus PB1-F2 protein.
Authors: Le Goffic R, Leymarie O, Chevalier C, Rebours E, Da Costa B, Vidic J, Descamps D, Sallenave JM, Rauch M, Samson M, Delmas B
PLoS Pathog., 2011;7(8):e1002202.
Species: Mouse
Sample Types: BALF
-
CD4 T cells promote rather than control tuberculosis in the absence of PD-1-mediated inhibition.
Authors: Barber DL, Mayer-Barber KD, Feng CG
J. Immunol., 2011;186(3):1598-607.
Species: Mouse
Sample Types: BALF
-
Phosphoinositide 3-kinase gamma plays a critical role in bleomycin-induced pulmonary inflammation and fibrosis in mice.
Authors: Russo RC, Garcia CC, Barcelos LS, Rachid MA, Guabiraba R, Roffe E, Souza AL, Sousa LP, Mirolo M, Doni A, Cassali GD, Pinho V, Locati M, Teixeira MM
J. Leukoc. Biol., 2011;89(2):269-82.
Species: Mouse
Sample Types: Tissue Homogenates
-
Endothelial cells are central orchestrators of cytokine amplification during influenza virus infection.
Authors: Teijaro JR, Walsh KB, Cahalan S, Fremgen DM, Roberts E, Scott F, Martinborough E, Peach R, Oldstone MB, Rosen H
Cell, 2011;146(6):980-91.
Species: Mouse
Sample Types: BALF
-
Api6/AIM/Sp{alpha}/CD5L Overexpression in Alveolar Type II Epithelial Cells Induces Spontaneous Lung Adenocarcinoma.
Authors: Li Y, Qu P, Wu L, Li B, Du H, Yan C
Cancer Res., 2011;71(16):5488-99.
Species: Mouse
Sample Types: Serum
-
The Therapeutic Potential of the Humoral Pattern Recognition Molecule PTX3 in Chronic Lung Infection Caused by Pseudomonas aeruginosa.
Authors: Moalli F, Paroni M, Veliz Rodriguez T, Riva F, Polentarutti N, Bottazzi B, Valentino S, Mantero S, Nebuloni M, Mantovani A, Bragonzi A, Garlanda C
J. Immunol., 2011;186(9):5425-34.
Species: Mouse
Sample Types: Tissue Homogenates
-
Alpha-Galactosylceramide-induced airway eosinophilia is mediated through the activation of NKT cells.
Authors: Chuang YH, Wang TC, Jen HY, Yu AL, Chiang BL
J. Immunol., 2010;186(8):4687-92.
Species: Mouse
Sample Types: BALF
-
Th17 cells are the dominant T cell subtype primed by Shigella flexneri mediating protective immunity.
Authors: Sellge G, Magalhaes JG, Konradt C, Fritz JH, Salgado-Pabon W, Eberl G, Bandeira A, Di Santo JP, Sansonetti PJ, Phalipon A
J. Immunol., 2010;184(4):2076-85.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Mucosal delivery of human papillomavirus pseudovirus-encapsidated plasmids improves the potency of DNA vaccination.
Authors: Graham BS, Kines RC, Corbett KS, Nicewonger J, Roberts JN, Schiller JT, Buck CB
Mucosal Immunol, 2010;3(5):475-86.
Species: Mouse
Sample Types: BALF
-
A critical role for C5L2 in the pathogenesis of experimental allergic asthma.
Authors: Zhang X, Schmudde I, Laumonnier Y, Pandey MK, Clark JR, Konig P, Gerard NP, Gerard C, Wills-Karp M, Kohl J
J. Immunol., 2010;185(11):6741-52.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Metabolic syndrome and altered gut microbiota in mice lacking Toll-like receptor 5.
Authors: Vijay-Kumar M, Aitken JD, Carvalho FA, Cullender TC, Mwangi S, Srinivasan S, Sitaraman SV, Knight R, Ley RE, Gewirtz AT
Science, 2010;328(5975):228-31.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Expression of bioactive single-chain murine IL-12 in transgenic plants.
Authors: Liu J, Dolan MC, Reidy M, Cramer CL
J. Interferon Cytokine Res., 2009;28(0):381-92.
Species: Mouse
Sample Types: Cell Culture Supernates
-
A chlamydial type III-secreted effector protein (Tarp) is predominantly recognized by antibodies from humans infected with Chlamydia trachomatis and induces protective immunity against upper genital tract pathologies in mice.
Authors: Wang J, Chen L, Chen F, Zhang X, Zhang Y, Baseman J, Perdue S, Yeh IT, Shain R, Holland M, Bailey R, Mabey D, Yu P, Zhong G
Vaccine, 2009;27(22):2967-80.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Elevated asymmetric dimethylarginine alters lung function and induces collagen deposition in mice.
Authors: Wells SM, Buford MC, Migliaccio CT, Holian A
Am. J. Respir. Cell Mol. Biol., 2009;40(2):179-88.
Species: Mouse
Sample Types: BALF
-
Mucosal immunity in mice induced by orally administered transgenic rice.
Authors: Zhang X, Yuan Z, Duan Q, Zhu H, Yu H, Wang Q
Vaccine, 2009;27(10):1596-600.
Species: Mouse
Sample Types: Cell Culture Supernates
-
The IFN regulatory factor 7-dependent type I IFN response is not essential for early resistance against murine cytomegalovirus infection.
Authors: Steinberg C, Eisenacher K, Gross O, Reindl W, Schmitz F, Ruland J, Krug A
Eur. J. Immunol., 2009;39(4):1007-18.
Species: Mouse
Sample Types: Serum
-
Effects of umbelliferone in a murine model of allergic airway inflammation.
Authors: Vasconcelos JF, Teixeira MM, Barbosa-Filho JM, Agra MF, Nunes XP, Giulietti AM, Ribeiro-Dos-Santos R, Soares MB
Eur. J. Pharmacol., 2009;609(1):126-31.
Species: Mouse
Sample Types: BALF
-
CD69+ CD4+ CD25- T cells, a new subset of regulatory T cells, suppress T cell proliferation through membrane-bound TGF-beta 1.
Authors: Han Y, Guo Q, Zhang M, Chen Z, Cao X
J. Immunol., 2009;182(1):111-20.
Species: Mouse
Sample Types: Cell Culture Supernates
-
A conjugated linoleic acid-enriched beef diet attenuates lipopolysaccharide-induced inflammation in mice in part through PPARgamma-mediated suppression of toll-like receptor 4.
Authors: Reynolds CM, Draper E, Keogh B, Rahman A, Moloney AP, Mills KH, Loscher CE, Roche HM
J. Nutr., 2009;139(12):2351-7.
Species: Mouse
Sample Types: Serum
-
Lack of Toll IL-1R8 exacerbates Th17 cell responses in fungal infection.
Authors: Bozza S, Zelante T, Moretti S, Bonifazi P, DeLuca A, D'Angelo C, Giovannini G, Garlanda C, Boon L, Bistoni F, Puccetti P, Mantovani A, Romani L
J. Immunol., 2008;180(6):4022-31.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Central role of MyD88-dependent dendritic cell maturation and proinflammatory cytokine production to control Brucella abortus infection.
Authors: Macedo GC, Magnani DM, Carvalho NB, Bruna-Romero O, Gazzinelli RT, Oliveira SC
J. Immunol., 2008;180(2):1080-7.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Adenosine A2A receptor activation inhibits T helper 1 and T helper 2 cell development and effector function.
Authors: Csoka B, Himer L, Selmeczy Z, Vizi ES, Pacher P, Ledent C, Deitch EA, Spolarics Z, Nemeth ZH, Hasko G
FASEB J., 2008;22(10):3491-9.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Streptococcus equi antigens adsorbed onto surface modified poly-epsilon-caprolactone microspheres induce humoral and cellular specific immune responses.
Authors: Florindo HF, Pandit S, Goncalves LM, Alpar HO, Almeida AJ
Vaccine, 2008;26(33):4168-77.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Administration of a synthetic TLR4 agonist protects mice from pneumonic tularemia.
Authors: Lembo A, Pelletier M, Iyer R, Timko M, Dudda JC, West TE, Wilson CB, Hajjar AM, Skerrett SJ
J. Immunol., 2008;180(11):7574-81.
Species: Mouse
Sample Types: Tissue Homogenates
-
Amelioration of delayed-type hypersensitivity responses by IL-27 administration.
Authors: Miyazaki Y, Shimanoe Y, Wang S, Yoshida H
Biochem. Biophys. Res. Commun., 2008;373(3):397-402.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Identification of cardiac troponin I sequence motifs leading to heart failure by induction of myocardial inflammation and fibrosis.
Authors: Kaya Z, Goser S, Buss SJ, Leuschner F, Ottl R, Li J, Volkers M, Zittrich S, Pfitzer G, Rose NR, Katus HA
Circulation, 2008;118(20):2063-72.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Amelioration of experimental autoimmune encephalomyelitis in IL-4Ralpha-/- mice implicates compensatory up-regulation of Th2-type cytokines.
Authors: Gaupp S, Cannella B, Raine CS
Am. J. Pathol., 2008;173(1):119-29.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Decreased pathology and prolonged survival of human DC-SIGN transgenic mice during mycobacterial infection.
Authors: Schaefer M, Reiling N, Fessler C, Stephani J, Taniuchi I, Hatam F, Yildirim AO, Fehrenbach H, Walter K, Ruland J, Wagner H, Ehlers S, Sparwasser T
J. Immunol., 2008;180(10):6836-45.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Functional regulatory T cells accumulate in aged hosts and promote chronic infectious disease reactivation.
Authors: Lages CS, Suffia I, Velilla PA, Huang B, Warshaw G, Hildeman DA, Belkaid Y, Chougnet C
J. Immunol., 2008;181(3):1835-48.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Protective immunity to systemic infection with attenuated Salmonella enterica serovar enteritidis in the absence of IL-12 is associated with IL-23-dependent IL-22, but not IL-17.
Authors: Schulz SM, Kohler G, Schutze N, Knauer J, Straubinger RK, Chackerian AA, Witte E, Wolk K, Sabat R, Iwakura Y, Holscher C, Muller U, Kastelein RA, Alber G
J. Immunol., 2008;181(11):7891-901.
Species: Mouse
Sample Types: Serum
-
CD40L-expressing CD8 T cells prime CD8alpha(+) DC for IL-12p70 production.
Authors: Wong KL, Lew FC, MacAry PA, Kemeny DM
Eur. J. Immunol., 2008;38(8):2251-62.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Surfactant protein D alters allergic lung responses in mice and human subjects.
Authors: Brandt EB, Mingler MK, Stevenson MD, Wang N, Khurana Hershey GK, Whitsett JA, Rothenberg ME
J. Allergy Clin. Immunol., 2008;121(5):1140-1147.e2.
Species: Mouse
Sample Types: BALF
-
Interleukin 10 regulates inflammatory cytokine synthesis to protect against lipopolysaccharide-induced abortion and fetal growth restriction in mice.
Authors: Robertson SA, Care AS, Skinner RJ
Biol. Reprod., 2007;76(5):738-48.
Species: Mouse
Sample Types: Serum
-
Mycobacterium tuberculosis antigens specifically modulate CCR2 and MCP-1/CCL2 on lymphoid cells from human pulmonary hilar lymph nodes.
Authors: Arias MA, Jaramillo G, Lopez YP, Mejia N, Mejia C, Pantoja AE, Shattock RJ, Garcia LF, Griffin GE
J. Immunol., 2007;179(12):8381-91.
Species: Human
Sample Types: Cell Culture Supernates
-
Lactoferrin enhanced efficacy of the BCG vaccine to generate host protective responses against challenge with virulent Mycobacterium tuberculosis.
Authors: Hwang SA, Wilk KM, Budnicka M, Olsen M, Bangale YA, Hunter RL, Kruzel ML, Actor JK
Vaccine, 2007;25(37):6730-43.
Species: Mouse
Sample Types: Cell Culture Supernates
-
CXCR3-dependent recruitment of antigen-specific T lymphocytes to the liver during murine cytomegalovirus infection.
Authors: Hokeness KL, Deweerd ES, Munks MW, Lewis CA, Gladue RP, Salazar-Mather TP
J. Virol., 2007;81(3):1241-50.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Deletion of TLR5 results in spontaneous colitis in mice.
Authors: Vijay-Kumar M, Sanders CJ, Taylor RT, Kumar A, Aitken JD, Sitaraman SV, Neish AS, Uematsu S, Akira S, Williams IR, Gewirtz AT
J. Clin. Invest., 2007;117(12):3909-21.
Species: Mouse
Sample Types: Serum
-
Differing effects of clarithromycin and azithromycin on cytokine production by murine dendritic cells.
Authors: Sugiyama K, Shirai R, Mukae H, Ishimoto H, Nagata T, Sakamoto N, Ishii H, Nakayama S, Yanagihara K, Mizuta Y, Kohno S
Clin. Exp. Immunol., 2007;147(3):540-6.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Nod1-mediated innate immune recognition of peptidoglycan contributes to the onset of adaptive immunity.
Authors: Fritz JH, Le Bourhis L, Sellge G, Magalhaes JG, Fsihi H, Kufer TA, Collins C, Viala J, Ferrero RL, Girardin SE, Philpott DJ
Immunity, 2007;26(4):445-59.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Soluble Interleukin IL-15Ralpha is generated by alternative splicing or proteolytic cleavage and forms functional complexes with IL-15.
Authors: Bulanova E, Budagian V, Duitman E, Orinska Z, Krause H, Ruckert R, Reiling N, Bulfone-Paus S
J. Biol. Chem., 2007;282(18):13167-79.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Chimeric NKG2D receptor-bearing T cells as immunotherapy for ovarian cancer.
Authors: Barber A, Zhang T, DeMars LR, Conejo-Garcia J, Roby KF, Sentman CL
Cancer Res., 2007;67(10):5003-8.
Species: Mouse
Sample Types: Cell Culture Supernates
-
An alternative pathway of NF-kappaB activation results in maturation and T cell priming activity of dendritic cells overexpressing a mutated IkappaBalpha.
Authors: Moore F, Buonocore S, Aksoy E, Ouled-Haddou N, Goriely S, Lazarova E, Paulart F, Heirman C, Vaeremans E, Thielemans K, Goldman M, Flamand V
J. Immunol., 2007;178(3):1301-11.
Species: Mouse
Sample Types: Cell Culture Supernates
-
CD40L disruption enhances Abeta vaccine-mediated reduction of cerebral amyloidosis while minimizing cerebral amyloid angiopathy and inflammation.
Authors: Obregon D, Hou H, Bai Y, Nikolic WV, Mori T, Luo D, Zeng J, Ehrhart J, Fernandez F, Morgan D, Giunta B, Town T, Tan J
Neurobiol. Dis., 2007;29(2):336-53.
Species: Mouse
Sample Types: Cell Culture Supernates
-
NKG2D receptor signaling enhances cytolytic activity by virus-specific CD8+ T cells: evidence for a protective role in virus-induced encephalitis.
Authors: Walsh KB, Lanier LL, Lane TE
J. Virol., 2007;82(6):3031-44.
Species: Mouse
Sample Types: Tissue Homogenates
-
The differential effect of Eriobotrya japonica hydrophilic leaf extract on cytokines production and modulation.
Authors: Matalka KZ, Ali D, Khawad AE, Qa'dan F
Cytokine, 2007;40(3):235-40.
Species: Mouse
Sample Types: Serum
-
Expansion of CD4+CD25+ regulatory T cells by intravenous immunoglobulin: a critical factor in controlling experimental autoimmune encephalomyelitis.
Authors: Ephrem A, Chamat S, Miquel C, Fisson S, Mouthon L, Caligiuri G, Delignat S, Elluru S, Bayry J, Lacroix-Desmazes S, Cohen JL, Salomon BL, Kazatchkine MD, Kaveri SV, Misra N
Blood, 2007;111(2):715-22.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Essential role for IL-10 in resistance to lipopolysaccharide-induced preterm labor in mice.
Authors: Robertson SA, Skinner RJ, Care AS
J. Immunol., 2006;177(7):4888-96.
Species: Mouse
Sample Types: Serum
-
Mucosal administration of CpG oligodeoxynucleotide elicits strong CC and CXC chemokine responses in the vagina and serves as a potent Th1-tilting adjuvant for recombinant gD2 protein vaccination against genital herpes.
Authors: Tengvall S, Lundqvist A, Eisenberg RJ, Cohen GH, Harandi AM
J. Virol., 2006;80(11):5283-91.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Differential involvement of TLR2 and TLR4 in host survival during pulmonary infection with Chlamydia pneumoniae.
Authors: Rodriguez N, Wantia N, Fend F, Durr S, Wagner H, Miethke T
Eur. J. Immunol., 2006;36(5):1145-55.
Species: Mouse
Sample Types: Tissue Homogenates
-
The effects of dehydroepiandrosterone (DHEA) on in vitro spleen cell proliferation and cytokine production.
Authors: Powell JM, Sonnenfeld G
J. Interferon Cytokine Res., 2006;26(1):34-9.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Transgenic expression of a CD83-immunoglobulin fusion protein impairs the development of immune-competent CD4-positive T cells.
Authors: Luthje K, Cramer SO, Ehrlich S, Veit A, Steeg C, Fleischer B, Bonin A, Breloer M
Eur. J. Immunol., 2006;36(8):2035-45.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Attenuation of primary nonfunction for syngeneic islet graft using sodium 4-phenylbutyrate.
Authors: Fu SH, Chen ST, Hsu BR
Transplant. Proc., 2005;37(4):1830-1.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Subcellular fractions of Brucella ovis distinctively induce the production of interleukin-2, interleukin-4, and interferon-gamma in mice.
Authors: Salas-Tellez E, Nunez del Arco A, Tenorio V, Diaz-Aparicio E, de la Garza M, Suarez-Guemes F
Can. J. Vet. Res., 2005;69(1):53-7.
Species: Mouse
Sample Types: Cell Culture Supernates
-
MyD88-dependent and -independent murine cytomegalovirus sensing for IFN-alpha release and initiation of immune responses in vivo.
Authors: Delale T, Paquin A, Asselin-Paturel C, Dalod M, Brizard G, Bates EE, Kastner P, Chan S, Akira S, Vicari A, Biron CA, Trinchieri G, Briere F
J. Immunol., 2005;175(10):6723-32.
Species: Mouse
Sample Types: Serum
-
Dendritic cells and NK cells stimulate bystander T cell activation in response to TLR agonists through secretion of IFN-alpha beta and IFN-gamma.
Authors: Kamath AT, Sheasby CE, Tough DF
J. Immunol., 2005;174(2):767-76.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Comparative immunomodulatory properties of a chitosan-MDP adjuvant combination following intranasal or intramuscular immunisation.
Authors: Moschos SA, Bramwell VW, Somavarapu S, Alpar HO
Vaccine, 2005;23(16):1923-30.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Immunosuppressive effects of CCL17 on pulmonary antifungal responses during pulmonary invasive aspergillosis.
Authors: Carpenter KJ, Hogaboam CM
Infect. Immun., 2005;73(11):7198-207.
Species: Mouse
Sample Types: Tissue Homogenates
-
Leukaemia inhibitory factor (LIF) is functionally linked to axotrophin and both LIF and axotrophin are linked to regulatory immune tolerance.
Authors: Metcalfe SM, Muthukumarana PA, Thompson HL, Haendel MA, Lyons GE
FEBS Lett., 2005;579(3):609-14.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Leukemia inhibitory factor is linked to regulatory transplantation tolerance.
Authors: Metcalfe SM, Watson TJ, Shurey S, Adams E, Green CJ
Transplantation, 2005;79(6):726-30.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Long-term control of Mycobacterium bovis BCG infection in the absence of Toll-like receptors (TLRs): investigation of TLR2-, TLR6-, or TLR2-TLR4-deficient mice.
Authors: Nicolle D, Fremond C, Pichon X, Bouchot A, Maillet I, Ryffel B, Quesniaux VJ
Infect. Immun., 2004;72(12):6994-7004.
Species: Mouse
Sample Types: Cell Lysates
-
Toll-like receptor 2 is required for optimal control of Listeria monocytogenes infection.
Authors: Torres D, Barrier M, Bihl F, Quesniaux VJ, Maillet I, Akira S, Ryffel B, Erard F
Infect. Immun., 2004;72(4):2131-9.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Comparison of immunogenicities of recombinant Plasmodium vivax merozoite surface protein 1 19- and 42-kiloDalton fragments expressed in Escherichia coli.
Authors: Sachdeva S, Ahmad G, Malhotra P, Mukherjee P, Chauhan VS
Infect. Immun., 2004;72(10):5775-82.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Fatal Mycobacterium tuberculosis infection despite adaptive immune response in the absence of MyD88.
Authors: Fremond CM, Yeremeev V, Nicolle DM, Jacobs M, Quesniaux VF, Ryffel B
J. Clin. Invest., 2004;114(12):1790-9.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Active hexose correlated compound enhances the immune function of mice in the hindlimb-unloading model of spaceflight conditions.
Authors: Aviles H, Belay T, Vance M, Sun B, Sonnenfeld G
J. Appl. Physiol., 2004;97(4):1437-44.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Transcutaneous immunization with cholera toxin B subunit adjuvant suppresses IgE antibody responses via selective induction of Th1 immune responses.
Authors: Anjuere F, George-Chandy A, Audant F, Rousseau D, Holmgren J, Czerkinsky C
J. Immunol., 2003;170(3):1586-92.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Intracellular thiols contribute to Th2 function via a positive role in IL-4 production.
Authors: Monick MM, Samavati L, Butler NS, Mohning M, Powers LS, Yarovinsky T, Spitz DR, Hunninghake GW
J. Immunol., 2003;171(10):5107-15.
Species: Mouse
Sample Types: Cell Culture Supernates
-
NKG2D CAR T-cell therapy inhibits the growth of NKG2D ligand heterogeneous tumors.
Authors: Spear P, Barber A, Rynda-Apple A, Sentman C
Immunol Cell Biol, 0;91(6):435-40.
Species: Mouse
Sample Types: Cell Culture Supernates
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We measured the INF-gamma level of culture supernatants from mouse spleen cells treated by group A or group B reagents. The data was normalized by comparing with that in control cells.
The kit worked great and very sensitive! We loved it.
You may use this kit with serum samples diluted >1:10.
Specificity: Specific
Sensitivity: Sensitive
Buffer: reagent diluent
Dilution: 100ng/ml (detection)