Mouse P-Cadherin Antibody

Catalog # Availability Size / Price Qty
AF761
AF761-SP
Detection of P‑Cadherin by Western Blot.
9 Images
Product Details
Citations (26)
FAQs
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Mouse P-Cadherin Antibody Summary

Species Reactivity
Mouse
Specificity
Detects P‑Cadherin in ELISAs and Western blots. In sandwich immunoassays, less than 2% cross-reactivity with recombinant human (rh) P‑Cadherin is observed and less than 0.3% cross-reactivity with recombinant mouse E-Cadherin, rhN-Cadherin, and rhCadherin-8 is observed.
Source
Polyclonal Goat IgG
Purification
Antigen Affinity-purified
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse P-Cadherin
Glu100-Gly647
Accession # Q8BSL6
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Endotoxin Level
<0.10 EU per 1 μg of the antibody by the LAL method.
Label
Unconjugated

Applications

Recommended Concentration
Sample
Western Blot
0.5 µg/mL
See below
Simple Western
25 µg/mL
See below
Flow Cytometry
0.25 µg/106 cells
XB2 mouse teratoma keratinocyte cell line
Immunohistochemistry
5-15 µg/mL
See below
Adhesion Blockade
The adhesion of A431 human epithelial carcinoma cells (1 x 105 cells/well) to immobilized Recombinant Mouse P-Cadherin Fc Chimera (Catalog # 761-MP, 10 µg/mL, 100 µL/well) was maximally inhibited (80-100%) by 50 µg/mL of the antibody.
 
CyTOF-ready
Ready to be labeled using established conjugation methods. No BSA or other carrier proteins that could interfere with conjugation.
 
Immunocytochemistry
5-15 µg/mL
See below

Mouse P-Cadherin Sandwich Immunoassay

Recommended Concentration
Reagent
ELISA Capture (Matched Antibody Pair)
0.2-0.8 µg/mL 

Use in combination with:

Detection Reagent: Mouse P‑Cadherin Biotinylated Antibody (Catalog # BAF761)

Standard: Recombinant Mouse P-Cadherin Fc Chimera Protein, CF (Catalog # 761-MP)

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Western Blot Detection of P-Cadherin antibody by Western Blot. View Larger

Detection of P‑Cadherin by Western Blot. Western blot shows lysates of mouse embryo tissue. PVDF membrane was probed with 0.5 µg/mL of Goat Anti-Mouse P-Cadherin Antigen Affinity-purified Polyclonal Antibody (Catalog # AF761) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF017). A specific band was detected for P-Cadherin at approximately 115 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

Immunocytochemistry P-Cadherin antibody in A431 Human Cell Line by Immunocytochemistry (ICC). View Larger

P‑Cadherin in A431 Human Cell Line. P-Cadherin was detected in immersion fixed A431 human epithelial carcinoma cell line using Goat Anti-Mouse P-Cadherin Antigen Affinity-purified Polyclonal Antibody (Catalog # AF761) at 10 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 493-conjugated Anti-Goat IgG Secondary Antibody (green; Catalog # NL003) and counterstained with DAPI (blue). Specific staining was localized to intercellular junctions. View our protocol for Fluorescent ICC Staining of Cells on Coverslips.

Immunohistochemistry P-Cadherin antibody in Mouse Embryo by Immunohistochemistry (IHC-Fr). View Larger

P‑Cadherin in Mouse Embryo. P-Cadherin was detected in immersion fixed frozen sections of mouse embryo (15 dpc) using Goat Anti-Mouse P-Cadherin Antigen Affinity-purified Polyclonal Antibody (Catalog # AF761) at 15 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS008) and counterstained with hematoxylin (blue). Specific staining was localized to connective tissue and lungs. View our protocol for Chromogenic IHC Staining of Frozen Tissue Sections.

Simple Western Detection of Mouse P-Cadherin antibody by Simple Western<sup>TM</sup>. View Larger

Detection of Mouse P‑Cadherin by Simple WesternTM. Simple Western lane view shows lysates of mouse embryo tissue, loaded at 0.2 mg/mL. A specific band was detected for P-Cadherin at approximately 115 kDa (as indicated) using 25 µg/mL of Goat Anti-Mouse P-Cadherin Antigen Affinity-purified Polyclonal Antibody (Catalog # AF761) followed by 1:50 dilution of HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF109). This experiment was conducted under reducing conditions and using the 12-230 kDa separation system.

Western Blot Detection of Mouse P-Cadherin by Western Blot View Larger

Detection of Mouse P-Cadherin by Western Blot BMPR1a regulated P-cadherin expression via p63 and Slug. (A) Immunohistochemistry staining for P-cadherin in control (n = 4 mice) and cKO (n = 3 mice) mammary glands at pregnancy day 14.5. Scale bar, 50 μm. (B) Western blotting for P-cadherin in mammary epithelial cells isolated from control and cKO mice at pregnancy day 14.5. beta -Tubulin was used as a loading control. Statistical analysis the expression of P-cadherin/ beta -Tubulin. n = 3 mice. (C) qRT-PCR analysis of Cdh3 in FACS-sorted control and cKO myoepithelial cells at pregnancy day 14.5. n = 4 biological replicates. (D) P-cadherin (red) and K14 (green) double immunofluorescence staining in HC11 mammary epithelial cells treated with BMP4 (50 ng/mL) for 24 h. n = 3 biological replicates. Scale bar, 25 μm. (E) Western blotting for P-cadherin in HC11 mammary epithelial cells treated with BMP4 (50 ng/mL) for 24 h. beta -Tubulin was used as a loading control. Statistical analysis the expression of P-cadherin/ beta -Tubulin. n = 3 biological replicates. (F) Scatter plot showing the correlation between BMPR1A and CDH3 expression in mammary glands from TCGA and GTEx data. Pearson’s coefficient test was performed to assess statistical significance. (G) Western blotting for P-cadherin in HC11 cells treated with p63 siRNA (sip63)/Slug siRNA (siSlug) and scramble RNA (NC) at 48 h. beta -Actin was used as a loading control. Statistical analysis the expression of P-cadherin/ beta -Actin. n = 3 biological replicates. (H) Immunofluorescence for P-cadherin (green) in HC11 cells treated with p63 siRNA (sip63)/Slug siRNA (siSlug) and scramble RNA (NC) at 48 h. n = 3 biological replicates. Scale bar, 25 μm. (I) Western blotting for K14, P-cadherin, p63 and Slug in HC11 cells treated with scramble RNA, p63 siRNA, Slug siRNA, or p63 siRNA and Slug siRNA at 48 h. beta -Actin was used as a loading control. Statistical analysis the expression of K14/ beta -Actin, P-cadherin/ beta -Actin, p63/ beta -Actin and Slug/ beta -Actin. n = 3 biological replicates. Data were presented as means ± SD. ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001. Image collected and cropped by CiteAb from the following open publication (https://pubmed.ncbi.nlm.nih.gov/34336839), licensed under a CC-BY license. Not internally tested by R&D Systems.

Western Blot Detection of Mouse P-Cadherin by Western Blot View Larger

Detection of Mouse P-Cadherin by Western Blot BMPR1a regulated P-cadherin expression via p63 and Slug. (A) Immunohistochemistry staining for P-cadherin in control (n = 4 mice) and cKO (n = 3 mice) mammary glands at pregnancy day 14.5. Scale bar, 50 μm. (B) Western blotting for P-cadherin in mammary epithelial cells isolated from control and cKO mice at pregnancy day 14.5. beta -Tubulin was used as a loading control. Statistical analysis the expression of P-cadherin/ beta -Tubulin. n = 3 mice. (C) qRT-PCR analysis of Cdh3 in FACS-sorted control and cKO myoepithelial cells at pregnancy day 14.5. n = 4 biological replicates. (D) P-cadherin (red) and K14 (green) double immunofluorescence staining in HC11 mammary epithelial cells treated with BMP4 (50 ng/mL) for 24 h. n = 3 biological replicates. Scale bar, 25 μm. (E) Western blotting for P-cadherin in HC11 mammary epithelial cells treated with BMP4 (50 ng/mL) for 24 h. beta -Tubulin was used as a loading control. Statistical analysis the expression of P-cadherin/ beta -Tubulin. n = 3 biological replicates. (F) Scatter plot showing the correlation between BMPR1A and CDH3 expression in mammary glands from TCGA and GTEx data. Pearson’s coefficient test was performed to assess statistical significance. (G) Western blotting for P-cadherin in HC11 cells treated with p63 siRNA (sip63)/Slug siRNA (siSlug) and scramble RNA (NC) at 48 h. beta -Actin was used as a loading control. Statistical analysis the expression of P-cadherin/ beta -Actin. n = 3 biological replicates. (H) Immunofluorescence for P-cadherin (green) in HC11 cells treated with p63 siRNA (sip63)/Slug siRNA (siSlug) and scramble RNA (NC) at 48 h. n = 3 biological replicates. Scale bar, 25 μm. (I) Western blotting for K14, P-cadherin, p63 and Slug in HC11 cells treated with scramble RNA, p63 siRNA, Slug siRNA, or p63 siRNA and Slug siRNA at 48 h. beta -Actin was used as a loading control. Statistical analysis the expression of K14/ beta -Actin, P-cadherin/ beta -Actin, p63/ beta -Actin and Slug/ beta -Actin. n = 3 biological replicates. Data were presented as means ± SD. ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001. Image collected and cropped by CiteAb from the following open publication (https://pubmed.ncbi.nlm.nih.gov/34336839), licensed under a CC-BY license. Not internally tested by R&D Systems.

Western Blot Detection of Mouse P-Cadherin by Western Blot View Larger

Detection of Mouse P-Cadherin by Western Blot BMPR1a regulated P-cadherin expression via p63 and Slug. (A) Immunohistochemistry staining for P-cadherin in control (n = 4 mice) and cKO (n = 3 mice) mammary glands at pregnancy day 14.5. Scale bar, 50 μm. (B) Western blotting for P-cadherin in mammary epithelial cells isolated from control and cKO mice at pregnancy day 14.5. beta -Tubulin was used as a loading control. Statistical analysis the expression of P-cadherin/ beta -Tubulin. n = 3 mice. (C) qRT-PCR analysis of Cdh3 in FACS-sorted control and cKO myoepithelial cells at pregnancy day 14.5. n = 4 biological replicates. (D) P-cadherin (red) and K14 (green) double immunofluorescence staining in HC11 mammary epithelial cells treated with BMP4 (50 ng/mL) for 24 h. n = 3 biological replicates. Scale bar, 25 μm. (E) Western blotting for P-cadherin in HC11 mammary epithelial cells treated with BMP4 (50 ng/mL) for 24 h. beta -Tubulin was used as a loading control. Statistical analysis the expression of P-cadherin/ beta -Tubulin. n = 3 biological replicates. (F) Scatter plot showing the correlation between BMPR1A and CDH3 expression in mammary glands from TCGA and GTEx data. Pearson’s coefficient test was performed to assess statistical significance. (G) Western blotting for P-cadherin in HC11 cells treated with p63 siRNA (sip63)/Slug siRNA (siSlug) and scramble RNA (NC) at 48 h. beta -Actin was used as a loading control. Statistical analysis the expression of P-cadherin/ beta -Actin. n = 3 biological replicates. (H) Immunofluorescence for P-cadherin (green) in HC11 cells treated with p63 siRNA (sip63)/Slug siRNA (siSlug) and scramble RNA (NC) at 48 h. n = 3 biological replicates. Scale bar, 25 μm. (I) Western blotting for K14, P-cadherin, p63 and Slug in HC11 cells treated with scramble RNA, p63 siRNA, Slug siRNA, or p63 siRNA and Slug siRNA at 48 h. beta -Actin was used as a loading control. Statistical analysis the expression of K14/ beta -Actin, P-cadherin/ beta -Actin, p63/ beta -Actin and Slug/ beta -Actin. n = 3 biological replicates. Data were presented as means ± SD. ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001. Image collected and cropped by CiteAb from the following open publication (https://pubmed.ncbi.nlm.nih.gov/34336839), licensed under a CC-BY license. Not internally tested by R&D Systems.

Western Blot Detection of Mouse P-Cadherin by Western Blot View Larger

Detection of Mouse P-Cadherin by Western Blot BMPR1a regulated P-cadherin expression via p63 and Slug. (A) Immunohistochemistry staining for P-cadherin in control (n = 4 mice) and cKO (n = 3 mice) mammary glands at pregnancy day 14.5. Scale bar, 50 μm. (B) Western blotting for P-cadherin in mammary epithelial cells isolated from control and cKO mice at pregnancy day 14.5. beta -Tubulin was used as a loading control. Statistical analysis the expression of P-cadherin/ beta -Tubulin. n = 3 mice. (C) qRT-PCR analysis of Cdh3 in FACS-sorted control and cKO myoepithelial cells at pregnancy day 14.5. n = 4 biological replicates. (D) P-cadherin (red) and K14 (green) double immunofluorescence staining in HC11 mammary epithelial cells treated with BMP4 (50 ng/mL) for 24 h. n = 3 biological replicates. Scale bar, 25 μm. (E) Western blotting for P-cadherin in HC11 mammary epithelial cells treated with BMP4 (50 ng/mL) for 24 h. beta -Tubulin was used as a loading control. Statistical analysis the expression of P-cadherin/ beta -Tubulin. n = 3 biological replicates. (F) Scatter plot showing the correlation between BMPR1A and CDH3 expression in mammary glands from TCGA and GTEx data. Pearson’s coefficient test was performed to assess statistical significance. (G) Western blotting for P-cadherin in HC11 cells treated with p63 siRNA (sip63)/Slug siRNA (siSlug) and scramble RNA (NC) at 48 h. beta -Actin was used as a loading control. Statistical analysis the expression of P-cadherin/ beta -Actin. n = 3 biological replicates. (H) Immunofluorescence for P-cadherin (green) in HC11 cells treated with p63 siRNA (sip63)/Slug siRNA (siSlug) and scramble RNA (NC) at 48 h. n = 3 biological replicates. Scale bar, 25 μm. (I) Western blotting for K14, P-cadherin, p63 and Slug in HC11 cells treated with scramble RNA, p63 siRNA, Slug siRNA, or p63 siRNA and Slug siRNA at 48 h. beta -Actin was used as a loading control. Statistical analysis the expression of K14/ beta -Actin, P-cadherin/ beta -Actin, p63/ beta -Actin and Slug/ beta -Actin. n = 3 biological replicates. Data were presented as means ± SD. ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001. Image collected and cropped by CiteAb from the following open publication (https://pubmed.ncbi.nlm.nih.gov/34336839), licensed under a CC-BY license. Not internally tested by R&D Systems.

Western Blot Detection of Mouse P-Cadherin by Western Blot View Larger

Detection of Mouse P-Cadherin by Western Blot BMPR1a regulated P-cadherin expression via p63 and Slug. (A) Immunohistochemistry staining for P-cadherin in control (n = 4 mice) and cKO (n = 3 mice) mammary glands at pregnancy day 14.5. Scale bar, 50 μm. (B) Western blotting for P-cadherin in mammary epithelial cells isolated from control and cKO mice at pregnancy day 14.5. beta -Tubulin was used as a loading control. Statistical analysis the expression of P-cadherin/ beta -Tubulin. n = 3 mice. (C) qRT-PCR analysis of Cdh3 in FACS-sorted control and cKO myoepithelial cells at pregnancy day 14.5. n = 4 biological replicates. (D) P-cadherin (red) and K14 (green) double immunofluorescence staining in HC11 mammary epithelial cells treated with BMP4 (50 ng/mL) for 24 h. n = 3 biological replicates. Scale bar, 25 μm. (E) Western blotting for P-cadherin in HC11 mammary epithelial cells treated with BMP4 (50 ng/mL) for 24 h. beta -Tubulin was used as a loading control. Statistical analysis the expression of P-cadherin/ beta -Tubulin. n = 3 biological replicates. (F) Scatter plot showing the correlation between BMPR1A and CDH3 expression in mammary glands from TCGA and GTEx data. Pearson’s coefficient test was performed to assess statistical significance. (G) Western blotting for P-cadherin in HC11 cells treated with p63 siRNA (sip63)/Slug siRNA (siSlug) and scramble RNA (NC) at 48 h. beta -Actin was used as a loading control. Statistical analysis the expression of P-cadherin/ beta -Actin. n = 3 biological replicates. (H) Immunofluorescence for P-cadherin (green) in HC11 cells treated with p63 siRNA (sip63)/Slug siRNA (siSlug) and scramble RNA (NC) at 48 h. n = 3 biological replicates. Scale bar, 25 μm. (I) Western blotting for K14, P-cadherin, p63 and Slug in HC11 cells treated with scramble RNA, p63 siRNA, Slug siRNA, or p63 siRNA and Slug siRNA at 48 h. beta -Actin was used as a loading control. Statistical analysis the expression of K14/ beta -Actin, P-cadherin/ beta -Actin, p63/ beta -Actin and Slug/ beta -Actin. n = 3 biological replicates. Data were presented as means ± SD. ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001. Image collected and cropped by CiteAb from the following open publication (https://pubmed.ncbi.nlm.nih.gov/34336839), licensed under a CC-BY license. Not internally tested by R&D Systems.

Reconstitution Calculator

Reconstitution Calculator

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Preparation and Storage

Reconstitution
Reconstitute at 0.2 mg/mL in sterile PBS.
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Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: P-Cadherin

Placental Cadherin (P-Cadherin or PCAD) is a member of the cadherin family of cell adhesion molecules. Cadherins are calcium-dependent transmembrane proteins, which bind to one another in a homophilic manner. On their cytoplasmic side, they associate with the three catenins, alpha, beta, and gamma (plakoglobin). This association links the cadherin protein to the cytoskeleton. Without association with the catenins, the cadherins are non-adhesive. Cadherins play a role in development, specifically in tissue formation. They may also help to maintain tissue architecture in the adult. P-Cadherin is a classical cadherin molecule. Classical cadherins consist of a large extracellular domain which contains DXD and DXNDN repeats responsible for mediating calcium-dependent adhesion, a single-pass transmembrane domain, and a short carboxy-terminal cytoplasmic domain responsible for interacting with the catenins. Constitutive P-Cadherin expression is found in the epidermis, mesothelium, corneal epithelium, and uterine decidua. Mouse P-Cadherin is an 822 amino acid (aa) protein with a 27 aa signal sequence and a 795 aa propeptide. The mature protein begins at aa 100 and has a 542 aa extracellular region, a 27 aa transmembrane region, and a 153 aa cytoplasmic region.

References
  1. Bussemakers, M.J.G. et al. (1993) Mol. Biol. Reports 17:123.
  2. Overduin, M. et al. (1995) Science 267:386.
  3. Takeichi, M. (1991) Science 251:1451.
  4. Nose, A. et al. (1987) EMBO J. 6:3655.
Long Name
Placental Cadherin
Entrez Gene IDs
1001 (Human); 12560 (Mouse); 116777 (Rat)
Alternate Names
CAD3; cadherin 3, P-cadherin (placental); cadherin 3, type 1, P-cadherin (placental); Cadherin-3; CDH3; CDHP; CDHPcalcium-dependent adhesion protein, placental; HJMD; PCAD; PCadherin; P-Cadherin; PCADP-cadherin; Placental cadherin

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Citations for Mouse P-Cadherin Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

26 Citations: Showing 1 - 10
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  1. An RNAi screen unravels the complexities of Rho GTPase networks in skin morphogenesis
    Authors: Melanie Laurin, Nicholas C Gomez, John Levorse, Ataman Sendoel, Megan Sribour, Elaine Fuchs
    eLife
  2. TLR2 Regulates Hair Follicle Cycle and Regeneration via BMP Signaling
    Authors: Luyang Xiong, Irina Zhevlakova, Xiaoxia Z. West, Detao Gao, Rakhylia Murtazina, Anthony Horak et al.
    bioRxiv
  3. SIRT 7 activates quiescent hair follicle stem cells to ensure hair growth in mice
    Authors: Guo Li, Xiaolong Tang, Shuping Zhang, Meiling Jin, Ming Wang, Zhili Deng et al.
    The EMBO Journal
  4. Role of the soluble epoxide hydrolase in the hair follicle stem cell homeostasis and hair growth
    Authors: Zumer Naeem, Sven Zukunft, Stephan Günther, Stefan Liebner, Andreas Weigert, Bruce D. Hammock et al.
    Pflügers Archiv - European Journal of Physiology
  5. m6A RNA methylation impacts fate choices during skin morphogenesis
    Authors: Linghe Xi, Thomas Carroll, Irina Matos, Ji-Dung Luo, Lisa Polak, H Amalia Pasolli et al.
    eLife
  6. Correction of aberrant growth preserves tissue homeostasis
    Authors: Samara Brown, Cristiana M. Pineda, Tianchi Xin, Jonathan Boucher, Kathleen C. Suozzi, Sangbum Park et al.
    Nature
  7. Decomposing a deterministic path to mesenchymal niche formation by two intersecting morphogen gradients
    Authors: Qu R, Gupta K, Dong D et al.
    Developmental cell
  8. Progenitors oppositely polarize WNT activators and inhibitors to orchestrate tissue development
    Authors: Irina Matos, Amma Asare, John Levorse, Tamara Ouspenskaia, June de la Cruz-Racelis, Laura-Nadine Schuhmacher et al.
    eLife
  9. Identification of hair shaft progenitors that create a niche for hair pigmentation
    Authors: Chung-Ping Liao, Reid C. Booker, Sean J. Morrison, Lu Q. Le
    Genes & Development
  10. Signalling by senescent melanocytes hyperactivates hair growth
    Authors: Wang, X;Ramos, R;Phan, AQ;Yamaga, K;Flesher, JL;Jiang, S;Oh, JW;Jin, S;Jahid, S;Kuan, CH;Nguyen, TK;Liang, HY;Shettigar, NU;Hou, R;Tran, KH;Nguyen, A;Vu, KN;Phung, JL;Ingal, JP;Levitt, KM;Cao, X;Liu, Y;Deng, Z;Taguchi, N;Scarfone, VM;Wang, G;Paolilli, KN;Wang, X;Guerrero-Juarez, CF;Davis, RT;Greenberg, EN;Ruiz-Vega, R;Vasudeva, P;Murad, R;Widyastuti, LHP;Lee, HL;McElwee, KJ;Gadeau, AP;Lawson, DA;Andersen, B;Mortazavi, A;Yu, Z;Nie, Q;Kunisada, T;Karin, M;Tuckermann, J;Esko, JD;Ganesan, AK;Li, J;Plikus, MV;
    Nature
    Species: Transgenic Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  11. Stem cells tightly regulate dead cell clearance to maintain tissue fitness
    Authors: Stewart, KS;Gonzales, KA;Yuan, S;Tierney, MT;Bonny, AR;Yang, Y;Infarinato, NR;Cowley, CJ;Levorse, JM;Pasolli, HA;Ghosh, S;Rothlin, CV;Fuchs, E;
    bioRxiv : the preprint server for biology
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  12. Transcriptomic Changes Predict Metabolic Alterations in LC3 Associated Phagocytosis in Aged Mice
    Authors: A Dhingra, JW Tobias, NJ Philp, K Boesze-Bat
    International Journal of Molecular Sciences, 2023-04-04;24(7):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  13. Sox2 in the dermal papilla regulates hair follicle pigmentation
    Authors: KJ Ng, J Lim, YN Tan, D Quek, Z Lim, N Pantelirei, C Clavel
    Oncogene, 2022-07-19;40(3):111100.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  14. Corticosterone inhibits GAS6 to govern hair follicle stem-cell quiescence
    Authors: S Choi, B Zhang, S Ma, M Gonzalez-C, D Stein, X Jin, ST Kim, YL Kang, A Besnard, A Rezza, L Grisanti, JD Buenrostro, M Rendl, M Nahrendorf, A Sahay, YC Hsu
    Nature, 2021-03-31;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  15. Distinct Regulatory Programs Control the Latent Regenerative Potential of Dermal Fibroblasts during Wound Healing
    Authors: S Abbasi, S Sinha, E Labit, NL Rosin, G Yoon, W Rahmani, A Jaffer, N Sharma, A Hagner, P Shah, R Arora, J Yoon, A Islam, A Uchida, CK Chang, JA Stratton, RW Scott, FMV Rossi, TM Underhill, J Biernaskie
    Cell Stem Cell, 2020-08-04;27(3):396-412.e6.
    Species: Mouse, Transgenic Mouse
    Sample Types: Whole Cells, Whole Tissue
    Applications: ICC, IHC
  16. miR-29a/b1 Inhibits Hair Follicle Stem Cell Lineage Progression by Spatiotemporally Suppressing WNT and BMP Signaling
    Authors: M Ge, C Liu, L Li, M Lan, Y Yu, L Gu, Y Su, K Zhang, Y Zhang, T Wang, C Liu, F Liu, M Li, L Xiong, K Wang, T He, Y Dai, Y Zhao, N Li, Z Yu, Q Meng
    Cell Rep, 2019-11-19;29(8):2489-2504.e4.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  17. Functionally Distinctive Ptch Receptors Establish Multimodal Hedgehog Signaling in the Tooth Epithelial Stem Cell Niche
    Authors: M Binder, P Chmielarz, PJ Mckinnon, LC Biggs, I Thesleff, A Balic
    Stem Cells, 2019-06-10;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  18. Cadherins in the retinal pigment epithelium (RPE) revisited: P-cadherin is the highly dominant cadherin expressed in human and mouse RPE in vivo
    Authors: X Yang, JY Chung, U Rai, N Esumi
    PLoS ONE, 2018-01-16;13(1):e0191279.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  19. Stem cell plasticity enables hair regeneration following Lgr5(+) cell loss
    Authors: JD Hoeck, B Biehs, AV Kurtova, NM Kljavin, F de Sousa E, B Alicke, H Koeppen, Z Modrusan, R Piskol, FJ de Sauvage
    Nat. Cell Biol., 2017-05-29;19(6):666-676.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  20. Stem Cell Lineage Infidelity Drives Wound Repair and Cancer
    Authors: Y Ge, NC Gomez, RC Adam, M Nikolova, H Yang, A Verma, CP Lu, L Polak, S Yuan, O Elemento, E Fuchs
    Cell, 2017-04-20;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  21. Role of cell and matrix-bound VEGF isoforms in lens development.
    Authors: Saint-Geniez M, Kurihara T, D'Amore PA
    Invest. Ophthalmol. Vis. Sci., 2008-08-29;50(1):311-21.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  22. Single-Cell Analysis Reveals a Hair Follicle Dermal Niche Molecular Differentiation Trajectory that Begins Prior to Morphogenesis
    Authors: Gupta K, Levinsohn J, Linderman G et al.
    Dev. Cell
  23. E‐cadherin mediates apical membrane initiation site localisation during de novo polarisation of epithelial cavities
    Authors: Xuan Liang, Antonia Weberling, Chun Yuan Hii, Magdalena Zernicka‐Goetz, Clare E Buckley
    The EMBO Journal
  24. Keratin-mediated hair growth and its underlying biological mechanism
    Authors: Seong Yeong An, Hyo-Sung Kim, So Yeon Kim, Se Young Van, Han Jun Kim, Jae-Hyung Lee et al.
    Communications Biology
  25. Loss of lamin B1 is a biomarker to quantify cellular senescence in photoaged skin
    Authors: Audrey Shimei Wang, Peh Fern Ong, Alexandre Chojnowski, Carlos Clavel, Oliver Dreesen
    Scientific Reports
  26. Molar Bud-to-Cap Transition Is Proliferation Independent
    Authors: S. Yamada, R. Lav, J. Li, A.S. Tucker, J.B.A. Green
    Journal of Dental Research

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