When Recombinant Human IL-2 R alpha Fc Chimera (Catalog # 1020‑RL) is coated at 1 μg/mL, Recombinant, Biotinylated Human IL-2 (Catalog # BT202) binds with an ED50 of in the low ng/mL (Left panel). When Recombinant Human VSIG3 Fc Chimera (Catalog # 9229-VS) is coated at 5 μg/mL, Biotinylated Recombinant Human VISTA/B7-H5 Fc Chimera (Catalog # BT7126) binds in the low μg/mL range (Right panel).
Biotinylated proteins can be powerful tools to assess protein/protein interactions in a range of assay formats, including immunoprecipitation, flow cytometry, immunoassays, and surface plasmon resonance. To be successful, it is crucial that biotinylation does not affect protein activity. For this reason, we hold our biotinylated proteins to the same specifications as their unlabeled counterparts.
Features and benefits
Only source of proteins tested in the same bioassay as unlabeled proteins to ensure specificity
Mammalian cell-expressed proteins labeled via carbohydrates to minimize biotin interference on protein function
Need a protein biotinylated or any other custom development work? Request a Quote
Our Custom Protein Development Team is comprised of experts dedicated to providing proteins that meet your specifications. This includes developing proteins from scratch, manufacturing to animal-free/GMP specifications, or adding labels such as biotin.