Biotinylated and Unlabeled Proteins Exhibit Similar Activity.
Biotinylated Recombinant Human TNF-alpha (Catalog # BT210) promotes cytotoxicity in L-929 mouse fibroblast cells in a manner similar to the unlabeled protein (Catalog # 210-TA) (left panel). Both biotinylated Recombinant Human VEGF 165 (Catalog # BT293) and the unlabeled protein (Catalog # 293-VE) stimulate HUVEC human umbilical vein endothelial cell proliferation (right panel).
Active Biotinylated Recombinant Proteins
Biotinylated proteins can be powerful tools to assess protein/protein interactions in a range of assay formats, including immunoprecipitation, flow cytometry, immunoassays, and surface plasmon resonance. To be successful, it is crucial that biotinylation does not affect protein activity. For this reason, we hold our biotinylated proteins to the same specifications as their unlabeled counterparts.
Features and benefits
Only source of proteins tested in the same bioassay as unlabeled proteins to ensure specificity
Mammalian cell-expressed proteins labeled via carbohydrates to minimize biotin interference on protein function
Need a protein biotinylated or any other custom development work?
Our Custom Protein Development Team is comprised of experts dedicated to providing proteins that meet your specifications. This includes developing proteins from scratch, manufacturing to animal-free/GMP specifications, or adding labels such as biotin.