19 results for "alpha-2A Adrenergic R/ADRA2A Small Molecules and Peptides" in Products
alpha-2A Adrenergic R/ADRA2A Small Molecules and Peptides
Alpha-2-adrenergic receptors, including ADRA2A, are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Studies in mouse revealed that both ADRA2A and ADRA2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. The ADRA2A subtype inhibited transmitter release at high stimulation frequencies, whereas the ADRA2C subtype modulated neurotransmission at lower levels of nerve activity.
α2A agonist
| Chemical Name: | [(2,6-Dichlorophenyl)acetyl]guanidine hydrochloride |
| Purity: | ≥98% |
Selective α2A antagonist
| Chemical Name: | 2-[(4,5-Dihydro-1H-imidazol-2-yl)methyl]-2,3-dihydro-1-methyl-1H-isoindole maleate |
| Purity: | ≥98% |
Potent and non-selective β antagonist; also potent α1 antagonist
| Alternate Names: | BM 14190 |
| Chemical Name: | 1-(9H-Carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-2-propanol |
| Purity: | ≥98% |
α2 agonist. Also I1 ligand
| Chemical Name: | 2-[(2,6-Dichlorophenyl)amino-2-imidazoline hydrochloride |
| Purity: | ≥98% |
Selective α2 antagonist
| Chemical Name: | 17α-Hydroxyyohimban-16α-carboxylic acid methyl ester hydrochloride |
| Purity: | ≥98% |
Potent, selective α2D antagonist
| Chemical Name: | 2-(2,3-Dihydro-2-methoxy-1,4-benzodioxin-2-yl)-4,5-dihydro-1H-imidazole hydrochloride |
| Purity: | ≥98% |
Non-selective 5-HT, dopamine, adrenalin and histamine receptor antagonist; antipsychotic agent
| Chemical Name: | (3aR*,12bR*)-5-Chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrole maleate |
| Purity: | ≥98% |
Potent and selective α2 antagonist
| Chemical Name: | 6-Chloro-N-methyl-2,3,4,5-tetrahydro-1-H-3-benzazepine hydrochloride |
| Purity: | ≥98% |
α2 agonist
| Chemical Name: | 5-Bromo-6-(2-imidazolin-2-ylamino)quinoxaline |
α2 agonist. Water-soluble form of UK 14,304 (Cat. No. 0425)
| Chemical Name: | 5-Bromo-6-(2-imidazolin-2-ylamino)quinoxaline tartrate |
| Purity: | ≥98% |
Potent, highly selective α2 agonist. Active isomer of medetomidine (Cat. No. 5160)
| Alternate Names: | d-Medetomidine hydrochloride |
| Chemical Name: | 4-[(1S)-1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole hydrochloride |
| Purity: | ≥98% |
Selective α2 antagonist
| Chemical Name: | 5-(2-Ethyl-2,3-dihydro-1H-indene-2-yl)-1H-imidazole hydrochloride |
| Purity: | ≥98% |
I1 ligand. Also α2 agonist
| Chemical Name: | 2-[N-(Dicyclopropylmethyl)amino]oxazoline hemifumarate |
| Purity: | ≥98% |
Potent 5-HT2 antagonist; also 5-HT3, H1 and α2 antagonist; antidepressant
| Alternate Names: | Org 3770,6-Azamianserin |
| Chemical Name: | 1,2,3,4,10,14b-Hexahydro-2-methylpyrazino[2,1-a]pyrido[2,3-c][2]benzazepine |
| Purity: | ≥98% |
α2 agonist
| Chemical Name: | 5-(Chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-2,1,3-benzothiadiazol-4-amine hydrochloride |
| Purity: | ≥98% |
Potent and highly selective α2 agonist
| Chemical Name: | 4-[1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole hydrochloride |
| Purity: | ≥98% |
Potent and selective adrenergic α2B antagonist
| Chemical Name: | 1-[2-[[[3-(3,5-Dimethyl-4-isoxazolyl)imidazo[1,2-a]pyridin-7-yl]carbonyl]amino]ethyl]-4-(methylamino)pyridinium chloride |
| Purity: | ≥98% |
Selective α2 agonist
| Alternate Names: | Azepexole |
| Chemical Name: | 6-Ethyl-5,6,7,8-tetrahydro-4H-oxazolo[4,5-d]azepin-2-amine dihydrochloride |
| Purity: | ≥98% |
5-HT1A antagonist
| Chemical Name: | 1-(2-Methoxyphenyl)-4-(4-phthalimidobutyl)piperazine hydrobromide |
| Purity: | ≥98% |
