Having trouble trying to find the right product? Chat with our scientists below - we're here to help!
236 results for "Caspase-3" in Products
Caspase-3 Products
Caspase-3 is a widely expressed dimeric peptidase that is the major executioner caspase, the primary downstream mediator of apoptotic-associated proteolysis. Caspase-3 cleaves multiple substrates including PARP, proIL-16, PKC-gamma and -delta, proCaspases-6, -7, and -9, and beta-Catenin. Normally, it is an inactive, exclusively cytosolic homodimer. During apoptosis, however, proCaspase-3 is activated by cleavage into p20 and p12 subunits, and the p20 subunit is trimmed to yield a p17 subunit. Active Caspase-3 contains two p17 and two p12 subunits.
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, ICC/IF |
Loading...
| Reactivity: | Human, Mouse, Rat, Porcine, Chicken, +2 More |
| Details: | Mouse IgG1 kappa Monoclonal Clone #31A1067 |
| Applications: | KO, IHC, WB, Flow, ICC/IF, + 5 More |
Loading...
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Monoclonal Clone #269518 |
| Applications: | IHC, WB, Flow, ICC/IF |
Loading...
| Reactivity: | Human, Mouse, Rat, Gerbil |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, Flow, ICC/IF, IP |
![Immunohistochemistry: Caspase-3 Antibody - (active/cleaved) [NB100-56113]](https://resources.rndsystems.com/images/products/Caspase-3-Antibody-active-cleaved-Immunohistochemistry-NB100-56113-img0005.jpg "Immunohistochemistry: Caspase-3 Antibody - (active/cleaved) [NB100-56113]")
Loading...
| Reactivity: | Multi-Species |
Loading...
| Reactivity: | Human, Fish |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Immunohistochemistry-Paraffin: Caspase-3 Antibody [NB600-1235]](https://resources.rndsystems.com/images/products/Caspase-3-Antibody-Immunohistochemistry-Paraffin-NB600-1235-img0003.jpg "Immunohistochemistry-Paraffin: Caspase-3 Antibody [NB600-1235]")
Loading...
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #CPP32 4-1-18 |
| Applications: | IHC, WB, ICC/IF, Simple Western, IP |
![Western Blot: Caspase-3 Antibody (CPP32 4-1-18)BSA Free [NB500-210]](https://resources.rndsystems.com/images/products/Caspase-3-Antibody-CPP32-4-1-18-Western-Blot-NB500-210-img0008.jpg "Western Blot: Caspase-3 Antibody (CPP32 4-1-18)BSA Free [NB500-210]")
Loading...
| Reactivity: | Human, Mouse, Rat, Canine, Gerbil |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, Simple Western, IP, ChIP |
![Western Blot: Caspase-3 Antibody(Pro and Active) [NB100-56112]](https://resources.rndsystems.com/images/products/Caspase-3-Antibody-Pro-and-Active-Western-Blot-NB100-56112-img0010.jpg "Western Blot: Caspase-3 Antibody(Pro and Active) [NB100-56112]")
Loading...
| Reactivity: | Human, Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | KO, WB, Simple Western, IP |
Loading...
| Reactivity: | Human, Mouse |
| Assay Range: | 219-14000 pg/mL |
| Applications: | ELISA |
Loading...
| Reactivity: | Human |
| Source: | E. coli |
| Accession #: | P42574 |
| Applications: | Enzyme Activity |
Loading...
| Reactivity: | Human |
| Details: | Mouse IgG Monoclonal Clone #31A893 |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: Caspase-3 Antibody (31A893)BSA Free [NB100-56709]](https://resources.rndsystems.com/images/products/Caspase-3-Antibody-31A893-Western-Blot-NB100-56709-img0009.jpg "Western Blot: Caspase-3 Antibody (31A893)BSA Free [NB100-56709]")
Loading...
| Alternate Names: | CDDP |
| Chemical Name: | cis-Diaminodichloroplatinum |
Loading...
| Reactivity: | Human, Mouse, Rat, Porcine, Chicken, +2 More |
| Details: | Mouse IgG1 kappa Monoclonal Clone #31A1067 |
| Applications: | KO, IHC, WB, Flow, ICC/IF, + 2 More |
Loading...
| Reactivity: | Human |
Loading...
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #84803 |
| Applications: | KO, WB |
Loading...
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #CPP32 4-1-18 |
| Applications: | IHC, WB, ICC/IF, Simple Western, IP |
![Western Blot: Caspase-3 Antibody (CPP32 4-1-18)Azide and BSA Free [NBP2-80614]](https://resources.rndsystems.com/images/products/Caspase-3-Antibody-CPP32-4-1-18-Azide-and-BSA-Free-Western-Blot-NBP2-80614-img0001.jpg "Western Blot: Caspase-3 Antibody (CPP32 4-1-18)Azide and BSA Free [NBP2-80614]")
Loading...
| Reactivity: | Human, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Immunocytochemistry/ Immunofluorescence: Caspase-3 Antibody [NBP1-90125]](https://resources.rndsystems.com/images/products/Caspase-3-Antibody-Immunocytochemistry-Immunofluorescence-NBP1-90125-img0015.jpg "Immunocytochemistry/ Immunofluorescence: Caspase-3 Antibody [NBP1-90125]")
Loading...
| Reactivity: | Human |
| Details: | Mouse IgG Monoclonal Clone #31A893 |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: Caspase-3 Antibody (31A893)Azide and BSA Free [NBP2-80613]](https://resources.rndsystems.com/images/products/Caspase-3-Antibody-31A893-Azide-and-BSA-Free-Western-Blot-NBP2-80613-img0002.jpg "Western Blot: Caspase-3 Antibody (31A893)Azide and BSA Free [NBP2-80613]")
Loading...
| Reactivity: | Human |
| Source: | E. coli |
| Accession #: | AAA65015 |
| Applications: | Enzyme Activity |
Loading...
| Alternate Names: | Picropodophyllin |
| Chemical Name: | (5R,5aS,8aR,9R)-5,8,8a,9-Tetrahydro-9-hydroxy-5-(3,4,5-trimethoxyphenyl)-furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one |
| Purity: | ≥97% |
Loading...
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #7T1W5 |
| Applications: | KO, WB, ICC/IF |
![Western Blot: Caspase-3 Antibody (7T1W5)Active, Pro [NBP3-15840]](https://resources.rndsystems.com/images/products/Caspase-3-Antibody-1U1D9-Active-Pro-Western-Blot-NBP3-15840-img0003.jpg "Western Blot: Caspase-3 Antibody (7T1W5)Active, Pro [NBP3-15840]")
Loading...
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #1112I |
| Applications: | Dual ISH-IHC, ICC/IF |
Loading...
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Monoclonal Clone #269518 |
| Applications: | Flow |
Loading...
| Alternate Names: | SC 58635,Celebrex |
| Chemical Name: | 4-[5-(4-Methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-benzenesulfonamide |
| Purity: | ≥98% |
Loading...