167 results for "MEK1" in Products
MEK1 Products
MEK1 and MEK2, also known as MAP2K1 and MAP2K2, are activated in response to mitogenic stimuli. Activation occurs through dual phosphorylation at S218/S222 of MEK1 and S222/S226 of MEK2 by several upstream MAP3Ks. Both MEK1 and MEK2 are dual-specificity protein kinases, phosphorylating and activating ERK1 and ERK2 at Thr and Tyr positions.
Potent, selective inhibitor of MEK1 and 2
| Chemical Name: | 1,4-Diamino-2,3-dicyano-1,4-bis[2-aminophenylthio]butadiene |
Potent inhibitor of MEK1/2
| Alternate Names: | PD325901 |
| Chemical Name: | N-[(2R)-2,3-Dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide |
| Purity: | ≥99% |
MEK inhibitor
| Chemical Name: | 2-(2-Amino-3-methoxyphenyl)-4H-1-benzopyran-4-one |
| Purity: | ≥98% |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI1F5 |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: MEK1 Antibody (OTI1F5) [NBP1-47833]](https://resources.rndsystems.com/images/products/MEK1-Antibody-1F5-Western-Blot-NBP1-47833-img0001.jpg "Western Blot: MEK1 Antibody (OTI1F5) [NBP1-47833]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI1F5 |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: MEK1 Antibody (OTI1F5)Azide and BSA Free [NBP2-72643]](https://resources.rndsystems.com/images/products/MEK1-Antibody-OTI1F5-Azide-and-BSA-Free-Western-Blot-NBP2-72643-img0001.jpg "Western Blot: MEK1 Antibody (OTI1F5)Azide and BSA Free [NBP2-72643]")
| Reactivity: | Human, Mouse, Rat, Canine |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: MEK1 Antibody [NBP2-17265]](https://resources.rndsystems.com/images/products/MEK1-Antibody-Western-Blot-NBP2-17265-img0002.jpg "Western Blot: MEK1 Antibody [NBP2-17265]")
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: MEK1 [p Thr292] Antibody [NB500-145]](https://resources.rndsystems.com/images/products/MEK1-[p-Thr292]-Antibody-Western-Blot-NB500-145-img0001.jpg "Western Blot: MEK1 [p Thr292] Antibody [NB500-145]")
| Reactivity: | Human, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, Simple Western |
![Western Blot: MEK1 [p Thr386] Antibody [NB500-144]](https://resources.rndsystems.com/images/products/MEK1-[p-Thr386]-Antibody-Western-Blot-NB500-144-img0001.jpg "Western Blot: MEK1 [p Thr386] Antibody [NB500-144]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: MEK1 Antibody [NBP1-87790]](https://resources.rndsystems.com/images/products/MEK1-Antibody-Western-Blot-NBP1-87790-img0009.jpg "Western Blot: MEK1 Antibody [NBP1-87790]")
Selective inhibitor of MEK1 and MEK2; brain penetrant
| Chemical Name: | α-[Amino[(4-aminophenyl)thio]methylene]-2-(trifluoromethyl)benzeneacetonitrile |
| Purity: | ≥98% |
| Reactivity: | Human, Mouse, Rat, Bovine, Canine, +3 More |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: MEK1 [p Ser218, p Ser222] Antibody [NBP2-24542]](https://resources.rndsystems.com/images/products/MEK1-Antibody-Western-Blot-NBP2-24542-img0001.jpg "Western Blot: MEK1 [p Ser218, p Ser222] Antibody [NBP2-24542]")
| Reactivity: | Human, Mouse, Rat, Bovine, Canine, +3 More |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: MEK1 Antibody [NBP2-24560]](https://resources.rndsystems.com/images/products/MEK1-Antibody-Western-Blot-NBP2-24560-img0001.jpg "Western Blot: MEK1 Antibody [NBP2-24560]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | KO, IHC, WB |
![Western Blot: MEK1 AntibodyAzide and BSA Free [NBP3-02951]](https://resources.rndsystems.com/images/products/MEK1-Antibody-Western-Blot-NBP3-02951-img0004.jpg "Western Blot: MEK1 AntibodyAzide and BSA Free [NBP3-02951]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2A Monoclonal Clone #239421 |
| Applications: | WB |
Recombinant Monoclonal Antibody.
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #1020E |
| Applications: | WB |
Selective MEK inhibitor
| Alternate Names: | CI-1040 |
| Chemical Name: | 2-[(2-Chloro-4-iodophenyl)amino]-N-cyclopropylmethoxy)-3,4-difluorobenzamide |
| Purity: | ≥98% |
| Reactivity: | Human |
| Source: | Sf 21 (baculovirus) |
| Accession #: | Q02750.2 |
| Applications: | Enzyme Activity |
Potent MEK1 inhibitor. Also inhibits IκBα phosphorylation
| Alternate Names: | (-)-Arctigenin |
| Chemical Name: | (3R,4R)-4-[(3,4-Dimethoxyphenyl)methyl]dihydro-3-[(4-hydroxy-3-methoxyphenyl)methyl]-2(3H)-furanone |
| Purity: | ≥98% |
Selective inhibitor of MEK1/2
| Chemical Name: | N-(Cyclopropylmethoxy)-3,4,5-trifluoro-2-[(4-iodo-2-methylphenyl)amino]-benzamide |
| Purity: | ≥98% |
MEK1 inhibitor
| Chemical Name: | N-[5-[3,4-Difluoro-2-[(2-fluoro-4-iodophenyl)amino]phenyl]-1,3,4-oxadiazol-2-yl]-4-morpholineethanamine |
| Purity: | ≥98% |
Recombinant Monoclonal Antibody
| Reactivity: | Human, Rat |
| Details: | Rabbit IgG Monoclonal Clone #9B6 |
| Applications: | IHC, WB, ELISA, IP |
Potent and selective MEK inhibitor; orally bioavailable
| Chemical Name: | N-[3-[3-Cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1(2H)-yl]phenyl]acetamide |
| Purity: | ≥98% |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #3F10 |
| Applications: | IHC, WB, ELISA, IP |
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #SR1774 |
| Applications: | IHC, WB, ICC/IF |
