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16 results for "Small G Protein Inhibitors" in Products
Small G Protein Inhibitors
Like Gα proteins, small GTPases alternate between an 'on' state (bound to GTP) and an 'off' state (bound to GDP) and so function as binary switches that regulate cytosolic signaling pathways. GDP/GTP cycling is controlled by two types of regulatory proteins that associate with small GTPases. Guanine exchange factors (GEFs) promote the formation of the active, GTP bound form of RAS proteins while GTPase activating proteins (GAPs) accelerate GTPase activity, promoting the inactive, GDP bound form.
| Chemical Name: | N6-[2-[[4-(Diethylamino)-1-methylbutyl]amino]-6-methyl-4-pyrimidinyl]-2-methyl-4,6-quinolinediamine trihydrochloride |
| Purity: | ≥98% |
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| Chemical Name: | 5-(5-(7-(Trifluoromethyl)quinolin-4-ylthio)pentyloxy)-2-(morpholinomethyl)-4H-pyran-4-one dihydrochloride |
| Purity: | ≥98% |
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| Alternate Names: | CID 2950007 |
| Chemical Name: | 4-[4,5-Dihydro-5-(4-methoxyphenyl)-3-phenyl-1H-pyrazol-1-yl]benzenesulfonamide |
| Purity: | ≥98% |
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| Chemical Name: | 4-[3-(2-Chlorophenyl)-2-propen-1-ylidene]-1-phenyl-3,5-pyrazolidinedione |
| Purity: | ≥98% |
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| Chemical Name: | α-[(2-(3-Chlorophenyl)hydrazinylidene]-5-(1,1-dimethylethyl)-β-oxo-3-isoxazolepropanenitrile |
| Purity: | ≥98% |
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| Chemical Name: | D-Tryptophan (2E)-2-(6-quinoxalinylmethylene)hydrazide hydrochloride |
| Purity: | ≥98% |
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| Alternate Names: | Zometa |
| Chemical Name: | [1-Hydroxy-2-(1H-imidazol-1-yl)ethylidene]bisphosphonic acid |
| Purity: | ≥98% |
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| Chemical Name: | 2-[(2,3,4,9-Tetrahydro-6-phenyl-1H-carbazol-1-yl)amino]ethanol |
| Purity: | ≥98% |
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| Chemical Name: | N-[4-[5-(1,3-Benzodioxol-5-yl)-3-methoxy-1H-1,2,4-triazol-1-yl]phenyl]-2-(phenylthio)acetamide |
| Purity: | ≥98% |
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| Chemical Name: | 3-(4-Chlorophenyl)-5-(4-nitrophenyl)-2-(phenylmethyl)pyrazolo[1,5-a]pyrimidin-7(4H)-one |
| Purity: | ≥98% |
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| Chemical Name: | (2S)-2-[2-(Indan-5-yloxy)-9-(1,1'-biphenyl-4-yl)methyl)-9H-purin-6-ylamino]-3-phenyl-propan-1-ol |
| Purity: | ≥98% |
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| Chemical Name: | 2-[4-[(2S)-2-(2-Phenyl-1H-benzimidazol-1-yl)-2-(4-piperidinyl)ethoxy]phenyl]-1-(phenylmethyl)-1H-benzimidazole trihydrochloride |
| Purity: | ≥98% |
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| Chemical Name: | N-[3-[1,4-Dihydro-1-methyl-7-[(6-methyl-3-pyridinyl)amino]-2-oxopyrimido[4,5-d]pyrimidin-3(2H)-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide |
| Purity: | ≥98% |
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| Chemical Name: | 2,4-Dimethyl-1-[(2,4,6-trimethylphenyl)sulfonyl]-1H-pyrrole |
| Purity: | ≥98% |
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| Chemical Name: | N4-(9-Ethyl-9H-carbazol-3-yl)-N2-[3-(4-morpholinyl)propyl]-2,4-pyrimidinediamine |
| Purity: | ≥98% |
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| Chemical Name: | [4-[Bis(4-chlorophenyl)methyl]-1-piperazinyl](5-methyl-4-nitro-3-isoxazolyl)methanone |
| Purity: | ≥98% |
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