Human Nanog Antibody Summary
Trp153-Val305
Accession # ABZ92376
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Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Scientific Data

Detection of Human Nanog by Western Blot. Western blot shows lysates of BG01V human embryonic stem cells and Tera-2 human embryonic lung carcinoma cell line. PVDF membrane was probed with 1 µg/mL of Goat Anti-Human Nanog Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1997) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (HAF109). A specific band was detected for Nanog at approximately 40 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 9.

Detection of Nanog-regulated Genes by Chromatin Immunoprecipitation. BG01V human embryonic stem cells were fixed using formaldehyde, resuspended in lysis buffer, and sonicated to shear chromatin. Nanog/DNA complexes were immunoprecipitated using 5 µg Goat Anti-Human Nanog Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1997) or control antibody (AB-108-C) for 15 minutes in an ultrasonic bath, followed by Biotinylated Anti-Goat IgG Secondary Antibody (BAF109). Immunocomplexes were captured using 50 µL of MagCellect Streptavidin Ferrofluid (Catalog # MAG999) and DNA was purified using chelating resin solution. Thenanogpromoter was detected by standard PCR.

Nanog in BG01V Human Stem Cells. Nanog was detected in immersion fixed BG01V human embryonic stem cells using 10 µg/mL Goat Anti-Human Nanog Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1997) for 3 hours at room temperature. Cells were stained with the Northern-Lights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red; NL001) and counterstained with DAPI (blue). View our protocol for Fluorescent ICC Staining of Cells on Coverslips.

Nanog in BG01V Human Stem Cells-derived Embryoid Body. Nanog was detected in immersion fixed BG01V human embryonic stem cells-derived embryoid body using 10 µg/mL Goat Anti-Human Nanog Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1997) for 3 hours at room temperature. Cells were stained with the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red; NL001) and counterstained with DAPI (blue). View our protocol for Fluorescent ICC Staining of Cells on Coverslips.

Nanog in ADLF1 and FAB2 Stem Cell Lines. Nanog was detected in immersion fixed ADLF1 (top panel) and FAB2 (bottom panel) induced pluripotent stem cell lines using Goat Anti-Human Nanog Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1997) at 10 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red; NL001) and counterstained with DAPI (blue). Specific staining was localized to nuclei. View our protocol for Fluorescent ICC Staining of Stem Cells on Coverslips.

Nanog in Human Testicular Cancer. Nanog was detected in immersion fixed paraffin-embedded sections of human testicular cancer using Goat Anti-Human Nanog Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1997) at 1 µg/mL for 1 hour at room temperature followed by incubation with the Anti-Goat IgG VisUCyte™ HRP Polymer Antibody (VC004). Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic (CTS013). Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to cell nuclei. Staining was performed using our protocol for IHC Staining with VisUCyte HRP Polymer Detection Reagents.

Nanog in Human Testis. Nanog was detected in immersion fixed paraffin-embedded sections of normal human testis using Goat Anti-Human Nanog Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1997) at 1 µg/mL for 1 hour at room temperature followed by incubation with the Anti-Goat IgG VisUCyte™ HRP Polymer Antibody (VC004). Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic (CTS013). Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to cytoplasm in developing sperm cells. Staining was performed using our protocol for IHC Staining with VisUCyte HRP Polymer Detection Reagents.

Nanog in 13 d.p.c. mouse embryos. Nanog was detected in immersion fixed frozen sections of 13 d.p.c. mouse embryos using Goat Anti-Human Nanog Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1997) at 1 µg/mL for 1 hour at room temperature followed by incubation with the Anti-Goat IgG VisUCyte™ HRP Polymer Antibody (VC004). Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic (CTS013). Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to cell nuclei in developing CNS. Staining was performed using our protocol for IHC Staining with VisUCyte HRP Polymer Detection Reagents.

Detection of Human Nanog by Simple WesternTM. Simple Western lane view shows lysates of iPSC, loaded at 0.2 mg/mL. A specific band was detected for Nanog at approximately 55 kDa (as indicated) using 10 µg/mL of Goat Anti-Human Nanog Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1997). This experiment was conducted under reducing conditions and using the 12-230 kDa separation system.
Reconstitution Calculator
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: Nanog
Nanog is a member of the homeobox family of DNA binding transcription factors that has been shown to maintain pluripotency of embryonic stem cells. Its expression is high in undifferentiated embryonic stem cells is down-regulated during embryonic stem cell differentiation, concomitant with loss of pluripotency (1-3).
- Mitsui, K. et al. (2003) Cell 11:631.
- Chambers, I. et al. (2003) Cell 113:643.
- Hart, A.H. et al. (2004) Dev. Dyn. 230:187.
Product Datasheets
Citations for Human Nanog Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Citations: Showing 1 - 10
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Generation of human induced pluripotent stem cells (CHULAi001-A) from peripheral blood mononuclear cells of a glucose-6-phosphate dehydrogenase (G6PD) deficient subject carrying the Viangchan mutation
Authors: M Tongbaen, Y Matsumura, K Okita, K Leecharoen
Stem Cell Research, 2022;65(0):102953.
Species: Human
Sample Types: Transfected Whole Cells
Applications: ICC -
Kr�ppel-like factor 5 rewires NANOG regulatory network to activate human naive pluripotency specific LTR7Ys and promote naive pluripotency
Authors: Z Ai, X Xiang, Y Xiang, I Szczerbins, Y Qian, X Xu, C Ma, Y Su, B Gao, H Shen, MN Bin Ramli, D Chen, Y Liu, JJ Hao, HH Ng, D Zhang, YS Chan, W Liu, H Liang
Cell Reports, 2022;40(8):111240.
Species: Human
Sample Types: Cell Lysates
Applications: Immunoprecipitation -
Genome-wide screening identifies Polycomb repressive complex 1.3 as an essential regulator of human na�ve pluripotent cell reprogramming
Authors: AJ Collier, A Bendall, C Fabian, AA Malcolm, K Tilgner, CI Semprich, K Wojdyla, PS Nisi, K Kishore, VN Roamio Fra, B Mirshekar-, C D'Santos, K Plath, K Yusa, PJ Rugg-Gunn
Science Advances, 2022;8(12):eabk0013.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of a human induced pluripotent stem cell line FMUPDCi001-A from a patient with mental retardation, autosomal recessive 36 (MRT36) carrying the variants c.219dupA and c.587C�>�T in ADAT3
Authors: X Hu, S Xiong, X Zhou, L Sun
Stem Cell Research, 2022;61(0):102777.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of a human iPSC line CIBi011-A from amniocytes of a healthy fetus
Authors: Y Shi, S Wu, B Yang, B Yu, Y Yan, J Yang, M Chu, X Hu
Stem Cell Research, 2022;62(0):102801.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of the induced pluripotent stem cell line UKWNLi005-A derived from a patient with the GLA mutation c.376A�>�G of unknown pathogenicity in Fabry disease
Authors: M Breyer, T Klein, K Klug, E Klopocki, N Üçeyler
Stem Cell Research, 2022;61(0):102747.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
A Novel Cell-Based Model for a Rare Disease: The Tks4-KO Human Embryonic Stem Cell Line as a Frank-Ter Haar Syndrome Model System
Authors: L László, H Maczelka, T Takács, A Kurilla, Á Tilajka, L Buday, V Vas, Á Apáti
International Journal of Molecular Sciences, 2022;23(15):.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Delamination of trophoblast-like syncytia from the amniotic ectodermal analogue in human primed embryonic stem cell-based differentiation model
Authors: M Ohgushi, N Taniyama, A Vandenbon, M Eiraku
Cell Reports, 2022;39(12):110973.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Generation of a human iPSC line CIBi010-A with a reporter for ASGR1 using CRISPR/Cas9
Authors: J Fu, L Jiang, B Yu, Y Liu, R Wei, Y Hu, WI Ho, B Yang, M Chu, HF Tse, J Yang
Stem Cell Research, 2022;62(0):102800.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
In�vitro attachment and symmetry breaking of a human embryo model assembled from primed embryonic stem cells
Authors: M Simunovic, ED Siggia, AH Brivanlou
Cell Stem Cell, 2022;29(6):962-972.e4.
Species: Human
Sample Types: Whole Tissue
Applications: IHC -
Primary cilia and SHH signaling impairments in human and mouse models of Parkinson's disease
Authors: S Schmidt, MD Luecken, D Trümbach, S Hembach, KM Niedermeie, N Wenck, K Pflügler, C Stautner, A Böttcher, H Lickert, C Ramirez-Su, R Ahmad, MJ Ziller, JC Fitzgerald, V Ruf, WDJ van de Ber, AJ Jonker, T Gasser, B Winner, J Winkler, DM Vogt Weise, F Giesert, FJ Theis, W Wurst
Nature Communications, 2022;13(1):4819.
Species: Human
Sample Types: Whole Cells
Applications: IHC -
RNA-based generation of iPSCs from a boy carrying the mutation m.9185�T>C in the mitochondrial gene MT-ATP6 and from his healthy mother
Authors: T Steiner, A Zink, MT Henke, G Cecchetto, M Buenning, A Rossi, M Schuelke, A Prigione
Stem Cell Research, 2022;64(0):102920.
Species: Human
Sample Types: Whole Cells
Applications: IHC -
Generation of a homozygous knock-in human embryonic stem cell line expressing mEos4b-tagged CTR1
Authors: YH Chen, PS Huang, MH Wen, M Pan, DF Lee, TY Chen
Oncogene, 2022;63(0):102845.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Production of a human iPSC line from an early-onset Parkinson's disease patient with a novel CHCHD2 gene truncated mutation
Authors: Z Jiang, XJ Gu, WM Su, QQ Duan, JY Lin, B Cao, HF Shang, YP Chen
Stem Cell Research, 2022;64(0):102881.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Generation of a RRAGA knockout human iPSC line GIBHi002-A-5 using CRISPR/Cas9 technology
Authors: Y Sun, J Fu, J Yang, J Zhao, J Rong
Oncogene, 2022;63(0):102859.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Establishment of a human induced pluripotent stem cell line (TAUi008-A) derived from a multiple sclerosis patient
Authors: J Lotila, T Hyvärinen, H Skottman, L Airas, S Narkilahti, S Hagman
Oncogene, 2022;63(0):102865.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Generation of four iPSC lines from four patients with Leigh syndrome carrying homoplasmic mutations m.8993T�>�G or m.8993T�>�C in the mitochondrial gene MT-ATP6
Authors: C Lorenz, A Zink, MT Henke, S Staege, B Mlody, M Bünning, E Wanker, S Diecke, M Schuelke, A Prigione
Stem Cell Research, 2022;61(0):102742.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of two human induced pluripotent stem cell (hiPSC) lines derived from unrelated Marfan Syndrome patients
Authors: J Borsoi, M Morato-Mar, F de Araújo, L Assis Pere, LE Farinha-Ar, R Delgado Sa, AB Alvarez Pe, L Veiga Pere
Stem Cell Research, 2021;54(0):102407.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation and characterization of an endogenously tagged SPG11-human iPSC line by CRISPR/Cas9 mediated knock-in
Authors: L Krumm, T Pozner, J Kaindl, M Regensburg, C Günther, S Turan, R Asadollahi, A Rauch, B Winner
Stem Cell Research, 2021;56(0):102520.
Species: Human
Sample Types: Whole Cells
Applications: ICC/IF -
Generation and characterization of a human iPSC line SANi006-A from a Gray Platelet Syndrome patient
Authors: CEM Aarts, E Varga, S Webbers, J Geissler, M von Linder, TW Kuijpers, E van den Ak
Stem Cell Research, 2021;55(0):102443.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of three human induced pluripotent stem cell sublines (UCLAi005-A, UCLAi005-B and UCLAi005-C) for reproductive science research
Authors: EC Pandolfi, TJ Hunt, S Goldsmith, K Hurlbut, SJ Silber, AT Clark
Stem Cell Research, 2021;54(0):102409.
Species: Human
Sample Types: Whole Cells
Applications: IHC -
Comparative evaluation of isogenic mesodermal and ectomesodermal chondrocytes from human iPSCs for cartilage regeneration
Authors: MS Lee, MJ Stebbins, H Jiao, HC Huang, EM Leiferman, BE Walczak, SP Palecek, EV Shusta, WJ Li
Science Advances, 2021;7(21):.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Non-invasive and high-throughput interrogation of exon-specific isoform expression
Authors: DJ Truong, T Phlairahar, B E beta wein, C Gruber, D Tümen, E Baligács, N Armbrust, FL Vaccaro, EM Lederer, EM Beck, J Geilenkeus, S Göppert, L Krumwiede, C Grätz, G Raffl, D Schwarz, M Zirngibl, M Živani?, M Beyer, JD Körner, T Santl, V Evsyukov, T Strau beta, SC Schwarz, GU Höglinger, P Heutink, S Doll, M Conrad, F Giesert, W Wurst, GG Westmeyer
Nature Cell Biology, 2021;23(6):652-663.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Cell-type-specific profiling of human cellular models of fragile X syndrome reveal PI3K-dependent defects in translation and neurogenesis
Authors: N Raj, ZT McEachin, W Harousseau, Y Zhou, F Zhang, ME Merritt-Ga, JM Taliaferro, M Kalinowska, SG Marro, CM Hales, E Berry-Krav, MW Wolf-Ochoa, V Martinez-C, M Wernig, L Chen, E Klann, ST Warren, P Jin, Z Wen, GJ Bassell
Cell Reports, 2021;35(2):108991.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot -
Age-dependent instability of mature neuronal fate in induced neurons from Alzheimer's patients
Authors: J Mertens, JR Herdy, L Traxler, ST Schafer, JCM Schlachetz, L Böhnke, DA Reid, H Lee, D Zangwill, DP Fernandes, RK Agarwal, R Lucciola, L Zhou-Yang, L Karbacher, F Edenhofer, S Stern, S Horvath, ACM Paquola, CK Glass, SH Yuan, M Ku, A Szücs, LSB Goldstein, D Galasko, FH Gage
Cell Stem Cell, 2021;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Dysregulation of mitochondria-lysosome contacts by GBA1 dysfunction in dopaminergic neuronal models of Parkinson's disease
Authors: S Kim, YC Wong, F Gao, D Krainc
Nature Communications, 2021;12(1):1807.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of a human induced pluripotent stem cell line (SMUSHi001-A) from a patient with 46, XX male sex reversal syndrome carrying the SRY gene
Authors: R Yan, S Wu, W Wang, M Chu, P Liu
Stem Cell Research, 2021;54(0):102397.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Generation of a homozygous knock-in human embryonic stem cell line expressing SNAP-tagged SOD1
Authors: PS Huang, MH Wen, X Xie, A Xu, DF Lee, TY Chen
Stem Cell Research, 2021;54(0):102415.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of an iPSC line (CRICKi001-A) from an individual with a germline SMARCA4 missense mutation and autism spectrum disorder
Authors: LG Devito, L Healy, S Mohammed, F Guillemot, C Dias
Stem Cell Research, 2021;53(0):102304.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Generation of a human iPSC line CIBi009-A from a patient with familial hypercholesterolemia carrying variants of LDLR c.T1241G and APOB c.G1618T
Authors: W Ge, Y Song, M Chu, Y Liu, B Yang, K Wang, B Yu, C Song, Y Wang, J Yang
Stem Cell Research, 2021;53(0):102347.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Defective metabolic programming impairs early neuronal morphogenesis in neural cultures and an organoid model of Leigh syndrome
Authors: G Inak, A Rybak-Wolf, P Lisowski, TM Pentimalli, R Jüttner, P Glažar, K Uppal, E Bottani, D Brunetti, C Secker, A Zink, D Meierhofer, MT Henke, M Dey, U Ciptasari, B Mlody, T Hahn, M Berruezo-L, N Karaiskos, M Di Virgili, JA Mayr, SB Wortmann, J Priller, M Gotthardt, DP Jones, E Mayatepek, W Stenzel, S Diecke, R Kühn, EE Wanker, N Rajewsky, M Schuelke, A Prigione
Nature Communications, 2021;12(1):1929.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
G-quadruplexes originating from evolutionary conserved L1 elements interfere with neuronal gene expression in Alzheimer's disease
Authors: R Hanna, A Flamier, A Barabino, G Bernier
Nature Communications, 2021;12(1):1828.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of insulin-producing pancreatic beta cells from multiple human stem cell lines
Authors: NJ Hogrebe, KG Maxwell, P Augsornwor, JR Millman
Nature Protocols, 2021;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Generation of three human induced pluripotent stem cell sublines (UCLAi004-A, UCLAi004-B, and UCLAi004-C) for reproductive science research
Authors: EC Pandolfi, TJ Hunt, S Goldsmith, K Hurlbut, SJ Silber, AT Clark
Stem Cell Research, 2021;54(0):102446.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Human iPSC lines from a Christianson syndrome patient with NHE6 W523X mutation, a biologically-related control, and CRISPR/Cas9 gene-corrected isogenic controls
Authors: L Ma, M Schmidt, EM Morrow
Stem Cell Research, 2021;54(0):102435.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of a human iPSC line QDMHi001-A from a patient with Marfan syndrome carrying a heterozygous c.6772�T�>�C variant in FBN1
Authors: S Wu, Z Zhang, L Wang, J Yu
Stem Cell Research, 2021;54(0):102390.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
A human forebrain organoid model of fragile X syndrome exhibits altered neurogenesis and highlights new treatment strategies
Authors: Y Kang, Y Zhou, Y Li, Y Han, J Xu, W Niu, Z Li, S Liu, H Feng, W Huang, R Duan, T Xu, N Raj, F Zhang, J Dou, C Xu, H Wu, GJ Bassell, ST Warren, EG Allen, P Jin, Z Wen
Nature Neuroscience, 2021;0(0):.
Species: Human
Sample Types: Organoid
Applications: ICC -
Principles of signaling pathway modulation for enhancing human naive pluripotency induction
Authors: J Bayerl, M Ayyash, T Shani, YS Manor, O Gafni, R Massarwa, Y Kalma, A Aguilera-C, M Zerbib, H Amir, D Sheban, S Geula, N Mor, L Weinberger, S Naveh Tass, V Krupalnik, B Oldak, N Livnat, S Tarazi, S Tawil, E Wildschutz, S Ashouokhi, L Lasman, V Rotter, S Hanna, D Ben-Yosef, N Novershter, S Viukov, JH Hanna
Cell Stem Cell, 2021;0(0):.
Species: Human
Sample Types: Cell Lysates
Applications: ChIP -
Human naive epiblast cells possess unrestricted lineage potential
Authors: G Guo, GG Stirparo, SE Strawbridg, D Spindlow, J Yang, J Clarke, A Dattani, A Yanagida, MA Li, S Myers, BN Özel, J Nichols, A Smith
Cell Stem Cell, 2021;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Patient-derived iPSCs link elevated mitochondrial respiratory complex I function to osteosarcoma in Rothmund-Thomson syndrome
Authors: BE Jewell, A Xu, D Zhu, MF Huang, L Lu, M Liu, EL Underwood, JH Park, H Fan, JA Gingold, R Zhou, J Tu, Z Huo, Y Liu, W Jin, YH Chen, Y Xu, SH Chen, N Rainusso, NK Berg, DA Bazer, C Vellano, P Jones, HK Eltzschig, Z Zhao, BA Kaipparett, R Zhao, LL Wang, DF Lee
PloS Genetics, 2021;17(12):e1009971.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot -
Induced pluripotent stem cells from subjects with Lesch-Nyhan disease
Authors: DJ Sutcliffe, AR Dinasarapu, JE Visser, JD Hoed, F Seifar, P Joshi, I Ceballos-P, T Sardar, EJ Hess, YV Sun, Z Wen, ME Zwick, HA Jinnah
Scientific Reports, 2021;11(1):8523.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
OCT4 cooperates with distinct ATP-dependent chromatin remodelers in na�ve and primed pluripotent states in human
Authors: X Huang, KM Park, P Gontarz, B Zhang, J Pan, Z McKenzie, LA Fischer, C Dong, S Dietmann, X Xing, PV Shliaha, J Yang, D Li, J Ding, T Lungjangwa, M Mitalipova, SA Khan, S Imsoonthor, N Jensen, T Wang, C Kadoch, R Jaenisch, J Wang, TW Theunissen
Nature Communications, 2021;12(1):5123.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Microglia-like Cells Promote Neuronal Functions in Cerebral Organoids
Authors: I Fagerlund, A Dougalis, A Shakirzyan, M Gómez-Budi, A Pelkonen, H Konttinen, S Ohtonen, MF Fazaludeen, M Koskuvi, J Kuusisto, D Hernández, A Pebay, J Koistinaho, T Rauramaa, Š Lehtonen, P Korhonen, T Malm
Cells, 2021;11(1):.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Inability to switch from ARID1A-BAF to ARID1B-BAF impairs exit from pluripotency and commitment towards neural crest formation in ARID1B-related neurodevelopmental disorders
Authors: L Pagliaroli, P Porazzi, AT Curtis, C Scopa, HMM Mikkers, C Freund, L Daxinger, S Deliard, SA Welsh, S Offley, CA Ott, B Calabretta, SA Brugmann, GWE Santen, M Trizzino
Nature Communications, 2021;12(1):6469.
Species: Human
Sample Types: Whole Cells
Applications: ChIP-Seq -
Assessing BRCA1 activity in DNA damage repair using human induced pluripotent stem cells as an approach to assist classification of BRCA1 variants of uncertain significance
Authors: M Ozgencil, J Barwell, M Tischkowit, L Izatt, I Kesterton, M Simpson, P Sharpe, P de Sepulve, E Voisset, E Solomon
PLoS ONE, 2021;16(12):e0260852.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of human induced pluripotent stem cell line, KRIBBi003-A, from urinary cells of a patient with glycogen storage disease type IXa
Authors: Y Shin, SJ Mun, J Lee, KS Chung, M Kim, C Kun Cheon, MJ Son
Stem Cell Research, 2021;57(0):102584.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Coactivation of GSK3beta and IGF-1 Attenuates Amyotrophic Lateral Sclerosis Nerve Fiber Cytopathies in SOD1 Mutant Patient-Derived Motor Neurons
Authors: HC Ting, HI Yang, HJ Harn, IM Chiu, HL Su, X Li, MF Chen, TJ Ho, CA Liu, YJ Tsai, TW Chiou, SZ Lin, CY Chang
Cells, 2021;10(10):.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Integrated pseudotime analysis of human pre-implantation embryo single-cell transcriptomes reveals the dynamics of lineage specification
Authors: D Meisterman, A Bruneau, S Loubersac, A Reignier, J Firmin, V François-C, S Kilens, Y Lelièvre, J Lammers, M Feyeux, P Hulin, S Nedellec, B Bretin, G Castel, N Allègre, S Covin, A Bihouée, M Soumillon, T Mikkelsen, P Barrière, C Chazaud, J Chappell, V Pasque, J Bourdon, T Fréour, L David
Cell Stem Cell, 2021;0(0):.
Species: Human
Sample Types: Embryo
Applications: IHC -
Modulating mesendoderm competence during human germ layer differentiation
Authors: JR Valcourt, RE Huang, S Kundu, D Venkatasub, RE Kingston, S Ramanathan
Cell Reports, 2021;37(6):109990.
Species: Human
Sample Types: Whole Cells
Applications: IF -
Decreased GLUT2 and glucose uptake contribute to insulin secretion defects in MODY3/HNF1A hiPSC-derived mutant &beta cells
Authors: BSJ Low, CS Lim, SSL Ding, YS Tan, NHJ Ng, VG Krishnan, SF Ang, CWY Neo, CS Verma, S Hoon, SC Lim, ES Tai, AKK Teo
Nature Communications, 2021;12(1):3133.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Imbalance of Excitatory/Inhibitory Neuron Differentiation in Neurodevelopmental Disorders with an NR2F1 Point Mutation
Authors: K Zhang, F Yu, J Zhu, S Han, J Chen, X Wu, Y Chen, T Shen, J Liao, W Guo, X Yang, R Wang, Y Qian, J Yang, L Cheng, Y Zhao, CC Hui, J Li, G Peng, S He, N Jing, K Tang
Cell Rep, 2020;31(3):107521.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
A human H1-HBB11-GFP reporter embryonic stem cell line (WAe001-A-2) generated using TALEN-based genome editing
Authors: V Alexeeva, IT Aydin, C Schaniel, AW Stranahan, SL D'Souza, JJ Bieker
Stem Cell Res, 2020;45(0):101837.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
The H2B ubiquitin-protein ligase RNF40 is required for somatic cell reprogramming
Authors: W Xie, M Miehe, S Laufer, SA Johnsen
Cell Death Dis, 2020;11(4):287.
Species: Mouse
Sample Types: Whole Cells
Applications: ICC -
Developmental potential of aneuploid human embryos cultured beyond implantation
Authors: MN Shahbazi, T Wang, X Tao, BAT Weatherbee, L Sun, Y Zhan, L Keller, GD Smith, A Pellicer, RT Scott, E Seli, M Zernicka-G
Nat Commun, 2020;11(1):3987.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Premature termination codon readthrough upregulates progranulin expression and improves lysosomal function in preclinical models of GRN deficiency
Authors: J Frew, A Baradaran-, AD Balgi, X Wu, TD Yan, S Arns, FS Shidmoossa, J Tan, JB Jaquith, KR Jansen-Wes, FC Lynn, FB Gao, L Petrucelli, HH Feldman, IR Mackenzie, M Roberge, HB Nygaard
Mol Neurodegener, 2020;15(1):21.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Non-transmissible MV Vector with Segmented RNA Genome Establishes Different Types of iPSCs from Hematopoietic Cells
Authors: T Hiramoto, M Tahara, J Liao, Y Soda, Y Miura, R Kurita, H Hamana, K Inoue, H Kohara, S Miyamoto, Y Hijikata, S Okano, Y Yamaguchi, Y Oda, K Ichiyanagi, H Toh, H Sasaki, H Kishi, A Ryo, A Muraguchi, M Takeda, K Tani
Mol. Ther., 2020;28(1):129-141.
Species: Human
Sample Types: Whole Cells
Applications: IHC -
Generation of induced pluripotent stem cell lines from a Crisponi/Cold induced sweating syndrome type 1 individual
Authors: L Schöning, NT Loges, Y Nitschke, IM Höben, A Röpke, L Crisponi, H Omran, F Rutsch, I Buers
Stem Cell Res, 2020;46(0):101820.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Generation of an integration-free induced pluripotent stem cell (iPSC) line (ZZUNEUi004-A) from a Wilson's disease patient harboring a homozygous Pro992Leu mutation in ATP7B gene
Authors: J Zhang, L Wei, D Chen, L Feng, C Wu, R Wang, X Li, H Liu
Stem Cell Res, 2020;44(0):101741.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
CRISPR/Cas9 mediated generation of human ARID1B heterozygous knockout hESC lines to model Coffin-Siris syndrome
Authors: T Boerstler, H Wend, M Krumbiegel, A Kavyanifar, A Reis, DC Lie, B Winner, S Turan
Stem Cell Res, 2020;47(0):101889.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of hypoimmunogenic human pluripotent stem cells via expression of membrane-bound and secreted &beta2m-HLA-G fusion proteins
Authors: L Shi, W Li, Y Liu, Z Chen, Y Hui, P Hao, X Xu, S Zhang, H Feng, B Zhang, S Zhou, N Li, L Xiao, L Liu, L Ma, X Zhang
Stem Cells, 2020;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Grafted human induced pluripotent stem cells improve the outcome of spinal cord injury: modulation of the lesion microenvironment
Authors: T Bellák, Z Fekécs, D Török, Z Táncos, C Nemes, Z Tézsla, L Gál, S Polgári, J Kobolák, A Dinnyés, A Nógrádi, K Pajer
Scientific Reports, 2020;10(1):22414.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of induced pluripotent stem cells (iPSCs) by retroviral transduction of skin fibroblasts from four patients suffering Williams-Beuren syndrome (7q11.23 deletion)
Authors: B Kuebler, B Aran, R Flores, LA Pérez-Jura, A Veiga, R Corominas, I Cuscó
Stem Cell Research, 2020;49(0):102087.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Generation of the iPSC line IISHDOi007-A from peripheral blood mononuclear cells from a patient with McArdle disease harbouring the mutation c.2392�T�>�C; p.Trp798Arg
Authors: V Cerrada, M García-Lóp, S Alvarez-Ga, A Moreno-Izq, A Lucia, M Rabasa Pér, J Arenas, ME Gallardo
Stem Cell Research, 2020;49(0):102108.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Generation of a human iPSC line GIBHi002-A-2 with a dual-reporter for NKX2-5 using TALENs
Authors: M Zhou, R Wei, Y Jiang, J Fu, Y Liu, B Yang, B Yu, Y Lin, X Ran, WH Lai, M Chu, Y Hu, J Yang, HF Tse
Stem Cell Research, 2020;50(0):102120.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Retromer stabilization results in neuroprotection in a model of Amyotrophic Lateral Sclerosis
Authors: L Muzio, R Sirtori, D Gornati, S Eleuteri, A Fossaghi, D Brancaccio, L Manzoni, L Ottoboni, L Feo, A Quattrini, E Mastrangel, L Sorrentino, E Scalone, G Comi, L Marinelli, N Riva, M Milani, P Seneci, G Martino
Nat Commun, 2020;11(1):3848.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
Derivation of induced pluripotent stem cells (iPSCs) by retroviral transduction of skin fibroblasts from four patients suffering 7q11.23 microduplication syndrome
Authors: B Kuebler, B Aran, R Flores, LA Pérez-Jura, A Veiga, I Cuscó, R Corominas
Stem Cell Res, 2020;49(0):102092.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Developmental potential of aneuploid human embryos cultured beyond implantation
Authors: MN Shahbazi, T Wang, X Tao, BAT Weatherbee, L Sun, Y Zhan, L Keller, GD Smith, A Pellicer, RT Scott, E Seli, M Zernicka-G
Nat Commun, 2020;11(1):3987.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of two induced pluripotent stem cell (iPSC) lines from an ALS patient with simultaneous mutations in KIF5A and MATR3 genes
Authors: DX Medina, A Boehringer, M Dominick, I Lorenzini, S Saez-Atien, EP Pioro, R Sattler, B Traynor, R Bowser
Stem Cell Research, 2020;50(0):102141.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of a human induced pluripotent stem cell line (SBWCHi001-A) from a patient with NEDSDV carrying a pathogenic mutation in CTNNB1 gene
Authors: R Yan, P Liu, F Li, M Chu, J Lei, F Wang, L Luo, X Xu
Stem Cell Res, 2020;49(0):102091.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of multiple iPSC clones from a male schizophrenia patient carrying de novo mutations in genes KHSRP, LRRC7, and KIR2DL1, and his parents
Authors: E Hathy, E Szabó, K Vincze, I Haltrich, E Kiss, N Varga, Z Erdei, G Várady, L Homolya, Á Apáti, JM Réthelyi
Stem Cell Research, 2020;51(0):102140.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Generation of a human induced pluripotent stem cell line (UEFi003-A) carrying heterozygous A673T variant in amyloid precursor protein associated with a reduced risk of Alzheimer's disease
Authors: T Rolova, YC Wu, M Koskuvi, J Voutilaine, TM Sonninen, J Kuusisto, M Laakso, RH Hämäläinen, J Koistinaho, Š Lehtonen
Stem Cell Res, 2020;48(0):101968.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Design of efficacious somatic cell genome editing strategies for recessive and polygenic diseases
Authors: J Carlson-St, A Das, AA Abdeen, D Fiflis, BI Grindel, S Saxena, T Akcan, T Alam, H Kletzien, L Kohlenberg, M Goedland, MJ Dombroe, K Saha
Nature Communications, 2020;11(1):6277.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Crisponi syndrome/cold-induced sweating syndrome type 2: Reprogramming of CS/CISS2 individual derived fibroblasts into three clones of one iPSC line
Authors: I Buers, L Schöning, N Tomas Loge, Y Nitschke, IM Höben, A Röpke, L Crisponi, H Omran, F Rutsch
Stem Cell Res, 2020;46(0):101855.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Retromer stabilization results in neuroprotection in a model of Amyotrophic Lateral Sclerosis
Authors: L Muzio, R Sirtori, D Gornati, S Eleuteri, A Fossaghi, D Brancaccio, L Manzoni, L Ottoboni, L Feo, A Quattrini, E Mastrangel, L Sorrentino, E Scalone, G Comi, L Marinelli, N Riva, M Milani, P Seneci, G Martino
Nat Commun, 2020;11(1):3848.
Species: Mouse
Sample Types: Whole Cells
Applications: ICC -
CRISPR/Cas9 mediated generation of human ARID1B heterozygous knockout hESC lines to model Coffin-Siris syndrome
Authors: T Boerstler, H Wend, M Krumbiegel, A Kavyanifar, A Reis, DC Lie, B Winner, S Turan
Stem Cell Res, 2020;47(0):101889.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Generation of a human induced pluripotent stem cell line, YCMi002-A, from a Factor VII deficiency patient carrying F7 mutations
Authors: DH Kim, CY Park, SR Cho, DW Kim
Stem Cell Res, 2020;49(0):102026.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Generation of 10 patient-specific induced pluripotent stem cells (iPSCs) to model Pitt-Hopkins Syndrome
Authors: SR Sripathy, Y Wang, RL Moses, A Fatemi, DA Batista, BJ Maher
Stem Cell Res, 2020;48(0):102001.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation, establishment and characterization of a pluripotent stem cell line (CVTTHi001-A) from primary fibroblasts isolated from a patient with activated PI3 kinase delta syndrome (APDS2)
Authors: M Inglés-Fer, M Martin-Ina, L Herrera, M Villaverde, S Santos, MA Vesga, E Garreta, I Martín-Rui, AM Aransay, J Anguita, B Barreña, LM Allende, LI Gonzalez-G, C Eguizabal
Stem Cell Res, 2020;49(0):102082.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of a human iPSC line CIBi008-A from amniotic fluid-derived cells of a fetus with &beta-thalassemia carrying variants of -28A�>�G and IVS-II-654C�>�T in HBB
Authors: S Wu, H Wei, M Chu, Z Weng
Stem Cell Res, 2020;49(0):102074.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Derivation of a human DOA iPSC line, IISHDOi006-A, with a mutation in the ACO2 gene: c.1999G>A; p.Glu667Lys
Authors: V Cerrada, M García-Lóp, A Moreno-Izq, C Villaverde, O Zurita, MI Martin-Mer, J Arenas, C Ayuso, ME Gallardo
Stem Cell Res, 2019;40(0):101566.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
SOX2 and SOX9 are markers of clinically aggressive disease in metastatic high-grade serous carcinoma
Authors: M Sherman-Sa, H Onallah, A Holth, R Reich, B Davidson
Gynecol. Oncol., 2019;0(0):.
Species: Human
Sample Types: Exosomes
Applications: Western Blot -
Human pre-valvular endocardial cells derived from pluripotent stem cells recapitulate cardiac pathophysiological valvulogenesis
Authors: T Neri, E Hiriart, PP van Vliet, E Faure, RA Norris, B Farhat, B Jagla, J Lefrancois, Y Sugi, T Moore-Morr, S Zaffran, RS Faustino, AC Zambon, JP Desvignes, D Salgado, RA Levine, JL de la Pomp, A Terzic, SM Evans, R Markwald, M Pucéat
Nat Commun, 2019;10(1):1929.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Induced pluripotent stem cell line heterozygous for p.R2447X mutation in filaggrin: KCLi002-A
Authors: N Kolundzic, P Khurana, L Devito, M Donne, C Hobbs, J Jeriha, XFCC Wong, JAE Common, EB Lane, S Dubrac, R Gruber, M Schmuth, TM Mauro, D Ilic
Stem Cell Res, 2019;38(0):101462.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
CRISPR/Cas9-mediated generation of a tyrosine hydroxylase reporter iPSC line for live imaging and isolation of dopaminergic neurons
Authors: C Calatayud, G Carola, I Fernández-, M Valtorta, S Jiménez-De, M Díaz, J Soriano-Fr, G Cappellett, J García-San, Á Raya, A Consiglio
Sci Rep, 2019;9(1):6811.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Establishment of PITX3-mCherry knock-in reporter human embryonic stem cell line (WAe009-A-23)
Authors: S Park, JE Yoo, DR Lee, J Jang, MS Cho, DS Kim, DW Kim
Stem Cell Res, 2019;39(0):101499.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Tcf7l1 acts as a suppressor for the self-renewal of liver cancer stem cells and is regulated by IGF/MEK/ERK signaling independent ofβ-catenin
Authors: J Shan, J Shen, M Wu, H Zhou, J Feng, C Yao, Z Yang, Q Ma, Y Luo, Y Wang, C Qian
Stem Cells, 2019;0(0):.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot -
Wnt Inhibition Facilitates RNA-Mediated Reprogramming of Human Somatic Cells to Naive Pluripotency
Authors: N Bredenkamp, J Yang, J Clarke, GG Stirparo, F von Meyenn, S Dietmann, D Baker, R Drummond, Y Ren, D Li, C Wu, M Rostovskay, S Eminli-Mei, A Smith, G Guo
Stem Cell Reports, 2019;13(6):1083-1098.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Control over single-cell distribution of G1 lengths by WNT governs pluripotency
Authors: J Jang, D Han, M Golkaram, M Audouard, G Liu, D Bridges, S Hellander, A Chialastri, SS Dey, LR Petzold, KS Kosik
PLoS Biol., 2019;17(9):e3000453.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Sex-specific transcriptional and proteomic signatures in schizophrenia
Authors: J Tiihonen, M Koskuvi, M Storvik, I Hyötyläine, Y Gao, KA Puttonen, R Giniatulli, E Poguzhelsk, I Ojansuu, O Vaurio, TD Cannon, J Lönnqvist, S Therman, J Suvisaari, J Kaprio, L Cheng, AF Hill, M Lähteenvuo, J Tohka, R Giniatulli, Š Lehtonen, J Koistinaho
Nat Commun, 2019;10(1):3933.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of three human induced pluripotent stem cell sublines (MZT04D, MZT04J, MZT04C) for reproductive science research
Authors: EC Pandolfi, EJ Rojas, E Sosa, JJ Gell, TJ Hunt, S Goldsmith, Y Fan, SJ Silber, AT Clark
Stem Cell Res, 2019;40(0):101576.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Superresolution architecture of cornerstone focal adhesions in human pluripotent stem cells
Authors: A Stubb, C Guzmán, E Närvä, J Aaron, TL Chew, M Saari, M Miihkinen, G Jacquemet, J Ivaska
Nat Commun, 2019;10(1):4756.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot -
Generation of an induced pluripotent stem cell line (UBCi001-A) from a presymptomatic individual carrying the R418X progranulin gene mutation
Authors: J Frew, X Wu, GY Hsiung, HH Feldman, IR Mackenzie, HB Nygaard
Stem Cell Res, 2019;41(0):101582.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of a genetically modified human embryonic stem cells expressing fluorescence tagged ATOX1
Authors: MH Wen, X Xie, J Tu, DF Lee, TY Chen
Stem Cell Res, 2019;41(0):101631.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
The intracellular Ca2+ concentration is elevated in cardiomyocytes differentiated from hiPSCs derived from a Duchenne muscular dystrophy patient
Authors: F Tsurumi, S Baba, D Yoshinaga, K Umeda, T Hirata, J Takita, T Heike
PLoS ONE, 2019;14(3):e0213768.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Engineering Genetic Predisposition in Human Neuroepithelial Stem Cells Recapitulates Medulloblastoma Tumorigenesis
Authors: M Huang, J Tailor, Q Zhen, AH Gillmor, ML Miller, H Weishaupt, J Chen, T Zheng, EK Nash, LK McHenry, Z An, F Ye, Y Takashima, J Clarke, H Ayetey, FMG Cavalli, B Luu, BS Moriarity, S Ilkhanizad, L Chavez, C Yu, KM Kurian, T Magnaldo, N Sevenet, P Koch, SM Pollard, P Dirks, MP Snyder, DA Largaespad, YJ Cho, JJ Phillips, FJ Swartling, AS Morrissy, M Kool, SM Pfister, MD Taylor, A Smith, WA Weiss
Cell Stem Cell, 2019;0(0):.
Species: Human
Sample Types: Whole Tissue
Applications: IHC -
Long Non-coding RNAs Associated With Neurodegeneration-Linked Genes Are Reduced in Parkinson's Disease Patients
Authors: M Elkouris, G Kouroupi, A Vourvoukel, N Papagianna, V Kaltezioti, R Matsas, L Stefanis, M Xilouri, PK Politis
Front Cell Neurosci, 2019;13(0):58.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Induced pluripotent stem cell (iPSC) line from an epidermolysis bullosa simplex patient heterozygous for keratin 5 E475G mutation and with the Dowling Meara phenotype
Authors: N Kolundzic, P Khurana, C Hobbs, M Rogar, S Ropret, H Törmä, D Ilic, M Liovic
Stem Cell Res, 2019;37(0):101424.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Ciliary gene RPGRIP1L is required for hypothalamic arcuate neuron development
Authors: L Wang, AJ De Solis, Y Goffer, KE Birkenbach, SE Engle, R Tanis, JM Levenson, X Li, R Rausch, M Purohit, JY Lee, J Tan, MC De Rosa, CA Doege, HL Aaron, GJ Martins, JC Brüning, D Egli, R Costa, N Berbari, RL Leibel, G Stratigopo
JCI Insight, 2019;4(3):.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Efficient generation of human primordial germ cell-like cells from pluripotent stem cells in a methylcellulose-based 3D system at large scale
Authors: X Wang, T Liao, C Wan, X Yang, J Zhao, R Fu, Z Yao, Y Huang, Y Shi, G Chang, Y Zheng, F Luo, Z Liu, Y Wang, X Mao, XY Zhao
PeerJ, 2019;6(0):e6143.
Species: Human
Sample Types: Whole Tissue
Applications: IHC-Fr -
Generation of gene-corrected iPSC line from Parkinson's disease patient iPSC line with alpha-SNCA A53T mutation
Authors: SY Lee, S Jeong, J Kim, SK Chung
Stem Cell Res, 2018;30(0):145-149.
-
High-efficiency RNA-based reprogramming of human primary fibroblasts
Authors: I Kogut, SM McCarthy, M Pavlova, DP Astling, X Chen, A Jakimenko, KL Jones, A Getahun, JC Cambier, AMG Pasmooij, MF Jonkman, DR Roop, G Bilousova
Nat Commun, 2018;9(1):745.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of a human induced pluripotent stem cell line from a patient with a rare A673T variant in amyloid precursor protein gene that reduces the risk for Alzheimer's disease
Authors: Š Lehtonen, I Höytyläine, J Voutilaine, TM Sonninen, J Kuusisto, M Laakso, RH Hämäläinen, M Oksanen, J Koistinaho
Stem Cell Res, 2018;30(0):96-99.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
TFAP2C regulates transcription in human naive pluripotency by opening enhancers
Authors: WA Pastor, W Liu, D Chen, J Ho, R Kim, TJ Hunt, A Lukianchik, X Liu, JM Polo, SE Jacobsen, AT Clark
Nat. Cell Biol., 2018;20(5):553-564.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot -
Bidirectional promoters exhibit characteristic chromatin modification signature associated with transcription elongation in both sense and antisense directions
Authors: RK Jangid, A Kelkar, VY Muley, S Galande
BMC Genomics, 2018;19(1):313.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot -
Biological characterization of human amniotic epithelial cells in a serum-free system and their safety evaluation
Authors: PJ Yang, WX Yuan, J Liu, JY Li, B Tan, C Qiu, XL Zhu, C Qiu, DM Lai, LH Guo, LY Yu
Acta Pharmacol. Sin., 2018;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells
Authors: TS Barakat, F Halbritter, M Zhang, AF Rendeiro, E Perenthale, C Bock, I Chambers
Cell Stem Cell, 2018;23(2):276-288.e8.
Species: Human
Sample Types: Cell Lysates
Applications: Immunoprecipitation -
Induced pluripotent stem cell line from an atopic dermatitis patient heterozygous for c.2282del4 mutation in filaggrin: KCLi001-A
Authors: L Devito, M Donne, N Kolundzic, P Khurana, C Hobbs, G Kaddour, S Dubrac, R Gruber, M Schmuth, T Mauro, D Ilic
Stem Cell Res, 2018;31(0):122-126.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
DMSO increases efficiency of genome editing at two non-coding loci
Authors: G Stratigopo, MC De Rosa, CA LeDuc, RL Leibel, CA Doege
PLoS ONE, 2018;13(6):e0198637.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
3D Modeling of Esophageal Development using Human PSC-Derived Basal Progenitors Reveals a Critical Role for Notch Signaling
Authors: Y Zhang, Y Yang, M Jiang, SX Huang, W Zhang, D Al Alam, S Danopoulos, M Mori, YW Chen, R Balasubram, SM Chuva de S, C Serra, M Bialecka, E Kim, S Lin, ALR Toste de C, PN Riccio, WV Cardoso, X Zhang, HW Snoeck, J Que
Cell Stem Cell, 2018;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: IHC -
Small non-coding RNA landscape of extracellular vesicles from human stem cells
Authors: S Kaur, AG Abu-Shahba, RO Paananen, H Hongisto, H Hiidenmaa, H Skottman, R Seppänen-K, B Mannerströ
Sci Rep, 2018;8(1):15503.
Species: Human
Sample Types: Whole Cells
Applications: Differentiation -
Generation of induced pluripotent stem cells (iPSCs) from human foreskin fibroblasts
Authors: F Erdlenbruc, J Rohwedel, P Ralfs, A Thomitzek, J Kramer, F Cakiroglu
Stem Cell Res, 2018;33(0):79-82.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Effects of the Extracts from Fruit and Stem of Camellia japonica on Induced Pluripotency and Wound Healing
Authors: H Jeon, JY Kim, JK Choi, E Han, CL Song, J Lee, YS Cho
J Clin Med, 2018;7(11):.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Human-Induced Pluripotent Stem Cells Manufactured Using a Current Good Manufacturing Practice-Compliant Process Differentiate Into Clinically Relevant Cells From Three Germ Layers
Authors: M Shafa, F Yang, T Fellner, MS Rao, BA Baghbadera
Front Med (Lausanne), 2018;5(0):69.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
yylncT Defines a Class of Divergently Transcribed lncRNAs and Safeguards the T-mediated Mesodermal Commitment of Human PSCs
Authors: S Frank, G Ahuja, D Bartsch, N Russ, W Yao, JC Kuo, JP Derks, VS Akhade, Y Kargapolov, T Georgomano, JE Messling, M Gramm, L Brant, R Rehimi, NE Vargas, A Kuroczik, TP Yang, RGA Sahito, J Franzen, J Hescheler, A Sachinidis, M Peifer, A Rada-Igles, M Kanduri, IG Costa, C Kanduri, A Papantonis, L Kurian
Cell Stem Cell, 2018;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: ICC -
WNT signaling memory is required for ACTIVIN to function as a morphogen in human gastruloids
Authors: A Yoney, F Etoc, A Ruzo, T Carroll, JJ Metzger, I Martyn, S Li, C Kirst, ED Siggia, AH Brivanlou
Elife, 2018;7(0):.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Improving Cell Survival in Injected Embryos Allows Primed Pluripotent Stem Cells to Generate Chimeric Cynomolgus Monkeys
Authors: Y Kang, Z Ai, K Duan, C Si, Y Wang, Y Zheng, J He, Y Yin, S Zhao, B Niu, X Zhu, L Liu, L Xiang, L Zhang, Y Niu, W Ji, T Li
Cell Rep, 2018;25(9):2563-2576.e9.
Species: Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque)
Sample Types: Whole Cells
Applications: ICC -
Preferential amplification of a human mitochondrial DNA deletion in vitro and in vivo
Authors: OM Russell, I Fruh, PK Rai, D Marcellin, T Doll, A Reeve, M Germain, J Bastien, KA Rygiel, R Cerino, AW Sailer, M Lako, RW Taylor, M Mueller, RN Lightowler, DM Turnbull, SB Helliwell
Sci Rep, 2018;8(1):1799.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
Differentiation-Defective Human Induced Pluripotent Stem Cells Reveal�Strengths and Limitations of the Teratoma Assay and In�Vitro Pluripotency Assays
Authors: MJ Bouma, M van Iterso, B Janssen, CL Mummery, DCF Salvatori, C Freund
Stem Cell Reports, 2017;8(5):1340-1353.
Species: Human
Sample Types: Whole Tissue
Applications: IHC-Fr -
Generation of FHL2 homozygous knockout lines from human embryonic stem cells by CRISPR/Cas9-mediated ablation
Authors: CW Chang, CC Chang, KC Hsia, SY Tsai
Stem Cell Res, 2017;27(0):21-24.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Effect of densely ionizing radiation on cardiomyocyte differentiation from human-induced pluripotent stem cells
Authors: E Baljinnyam, S Venkatesh, R Gordan, S Mareedu, J Zhang, LH Xie, EI Azzam, CK Suzuki, D Fraidenrai
Physiol Rep, 2017;5(15):.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of a GDE heterozygous mutation human embryonic stem cell line WAe001-A-14 by CRISPR/Cas9 editing
Authors: G Xu, D Guo, F Wu, N Abbas, K Lai, F Yuan, K You, Y Liu, Y Zhuang, Y Wu, Y Xu, Y Chen, F Yang, T Pan, YX Li
Stem Cell Res, 2017;27(0):38-41.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Human iPSC-Derived Neural Progenitors Are an Effective Drug Discovery Model for Neurological mtDNA Disorders
Authors: C Lorenz, P Lesimple, R Bukowiecki, A Zink, G Inak, B Mlody, M Singh, M Semtner, N Mah, K Aur‚, M Leong, O Zabiegalov, EM Lyras, V Pfiffer, B Fauler, J Eichhorst, B Wiesner, N Huebner, J Priller, T Mielke, D Meierhofer, Z Izsv k, JC Meier, F Bouillaud, J Adjaye, M Schuelke, EE Wanker, A LombŠs, A Prigione
Cell Stem Cell, 2017;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Induction of Pluripotent Stem Cells from a Manifesting Carrier of Duchenne Muscular Dystrophy and Characterization of Their X-Inactivation Status
Authors: Y Miyagoe-Su, T Nishiyama, M Nakamura, A Narita, F Takemura, S Masuda, N Minami, K Murayama, H Komaki, YI Goto, S Takeda
Stem Cells Int, 2017;2017(0):7906843.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of an ASGR1 homozygous mutant human embryonic stem cell line WAe001-A-6 using CRISPR/Cas9
Authors: Y Xu, Y Wu, D Guo, G Gao, K Lai, F Yang, K Wang, H Wu, L Lai, J Li, K Xu, YX Li
Stem Cell Res, 2017;22(0):29-32.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of integration-free induced pluripotent stem cell lines derived from two patients with X-linked Alport syndrome (XLAS)
Authors: B Kuebler, B Aran, L Miquel-Ser, Y Muñoz, E Ars, G Bullich, M Furlano, R Torra, M Marti, A Veiga, A Raya
Stem Cell Res, 2017;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Modeling of TREX1-Dependent Autoimmune Disease using Human Stem Cells Highlights L1 Accumulation as a Source of Neuroinflammation
Authors: CA Thomas, L Tejwani, CA Trujillo, PD Negraes, RH Herai, P Mesci, A Macia, YJ Crow, AR Muotri
Cell Stem Cell, 2017;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
HIF1? regulates single differentiated glioma cell dedifferentiation to stem-like cell phenotypes with high tumorigenic potential under hypoxia
Authors: P Wang, C Lan, S Xiong, X Zhao, Y Shan, R Hu, W Wan, S Yu, B Liao, G Li, J Wang, D Zou, B Chen, H Feng, N Wu
Oncotarget, 2017;8(17):28074-28092.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot -
Directed differentiation of human induced pluripotent stem cells into functional cholangiocyte-like cells
Authors: F Sampazioti, MC de Brito, I Geti, A Bertero, NR Hannan, L Vallier
Nat Protoc, 2017;12(4):814-827.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Establishment of an induced pluripotent stem cell (iPSC) line from a 9-year old male with autism spectrum disorder (ASD)
Authors: E Varga, C Nemes, I Bock, Z Táncos, S Berzsenyi, G Lévay, V Román, J Kobolák, A Dinnyés
Stem Cell Res, 2017;21(0):19-22.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Nicotinamide Ameliorates Disease Phenotypes in a Human iPSC Model of Age-Related Macular Degeneration
Authors: JS Saini, B Corneo, JD Miller, TR Kiehl, Q Wang, NC Boles, TA Blenkinsop, JH Stern, S Temple
Cell Stem Cell, 2017;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
TALEN-mediated shift of mitochondrial DNA heteroplasmy in MELAS-iPSCs with m.13513G>A mutation
Authors: N Yahata, Y Matsumoto, M Omi, N Yamamoto, R Hata
Sci Rep, 2017;7(1):15557.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
A Comprehensive TALEN-Based Knockout Library for Generating Human Induced Pluripotent Stem Cell-Based Models for Cardiovascular Diseases
Authors: I Karakikes, V Termglinch, DA Cepeda, J Lee, S Diecke, A Hendel, I Itzhaki, M Ameen, R Shrestha, H Wu, N Ma, NY Shao, T Seeger, NA Woo, KD Wilson, E Matsa, MH Porteus, V Sebastiano, JC Wu
Circ. Res, 2017;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of six multiple sclerosis patient-derived induced pluripotent stem cell lines
Authors: L Miquel-Ser, A Duarri, Y Muñoz, B Kuebler, B Aran, C Costa, M Martí, M Comabella, S Malhotra, X Montalban, A Veiga, A Raya
Stem Cell Res, 2017;24(0):155-159.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Cancer stem-like cells can be induced through dedifferentiation under hypoxic conditions in glioma, hepatoma and lung cancer
Authors: P Wang, WW Wan, SL Xiong, H Feng, N Wu
Cell Death Discov, 2017;3(0):16105.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot -
A Marfan syndrome human induced pluripotent stem cell line with a heterozygous FBN1 c.4082G>A mutation, ISMMSi002-B, for disease modeling
Authors: S Klein, JL Dvornik, AR Yarrabothu, C Schaniel
Stem Cell Res, 2017;23(0):73-76.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
A deleterious Nav1.1 mutation selectively impairs telencephalic inhibitory neurons derived from Dravet Syndrome patients
Elife, 2016;5(0):.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Development and production of good manufacturing practice grade human embryonic stem cell lines as source material for clinical application
Stem Cell Res, 2016;17(2):379-390.
Species: Human
Sample Types: Whole Cells
Applications: IHC -
Efficient CRISPR/Cas9-Mediated Versatile, Predictable, and Donor-Free Gene Knockout in Human Pluripotent Stem Cells
Stem Cell Reports, 2016;7(3):496-507.
Species: Human
Sample Types: Whole Cells
Applications: IHC-Fr -
Mesenchymal stromal cells derived from whole human umbilical cord exhibit similar properties to those derived from Wharton's jelly and bone marrow
FEBS Open Bio, 2016;6(11):1054-1066.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
A Novel Molecular and Functional Stemness Signature Assessing Human Cord Blood-Derived Endothelial Progenitor Cell Immaturity
Authors: O Guillevic, S Ferratge, J Pascaud, C Driancourt, J Boyer-Di-P, G Uzan
PLoS ONE, 2016;11(4):e0152993.
Species: Human
Sample Types: Whole Cells
Applications: IHC-Fr -
Generation of HEXA-deficient hiPSCs from fibroblasts of a Tay-Sachs disease patient
Stem Cell Res, 2016;17(2):289-291.
Species: Human
Sample Types: Whole Cells
Applications: IHC-Fr -
Characterisation of the Epigenetic Changes During Human Gonadal Primordial Germ Cells Reprogramming
Authors: C Eguizabal
Stem Cells, 2016;0(0):.
Species: Human
Sample Types: Whole Tissue
Applications: IHC-P -
Capturing the biology of disease severity in a PSC-based model of familial dysautonomia
Authors: N Zeltner, F Fattahi, NC Dubois, N Saurat, F Lafaille, L Shang, B Zimmer, J Tchieu, MA Soliman, G Lee, JL Casanova, L Studer
Nat. Med., 2016;22(12):1421-1427.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Neuronal Dysfunction in iPSC-Derived Medium Spiny Neurons from Chorea-Acanthocytosis Patients Is Reversed by Src Kinase Inhibition and F-Actin Stabilization
Authors: Florian Wegner
J. Neurosci., 2016;36(47):12027-12043.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
A Newly Defined and Xeno-Free Culture Medium Supports Every-Other-Day Medium Replacement in the Generation and Long-Term Cultivation of Human Pluripotent Stem Cells
PLoS ONE, 2016;11(9):e0161229.
Species: Human
Sample Types: Cell Culture Supernates
Applications: IHC -
An integration-free, virus-free rhesus macaque induced pluripotent stem cell line (riPSC89) from embryonic fibroblasts
Stem Cell Res, 2016;17(2):444-447.
Species: Primate - Macaca mulatta (Rhesus Macaque)
Sample Types: Whole Cells
Applications: IHC-Fr -
Dynamic regulation of the cancer stem cell compartment by Cripto-1 in colorectal cancer.
Authors: Francescangeli F, Contavalli P, De Angelis M, Baiocchi M, Gambara G, Pagliuca A, Fiorenzano A, Prezioso C, Boe A, Todaro M, Stassi G, Castro N, Watanabe K, Salomon D, De Maria R, Minchiotti G, Zeuner A
Cell Death Differ, 2015;22(10):1700-13.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Induced overexpression of Oct4A in human dental pulp cells enhances pluripotency and multilineage differentiation capability.
Authors: Liu L, Wu L, Wei X, Ling J
Stem Cells Dev, 2015;24(8):962-72.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
GGGGCC repeat expansion in C9orf72 compromises nucleocytoplasmic transport.
Authors: Freibaum B, Lu Y, Lopez-Gonzalez R, Kim N, Almeida S, Lee K, Badders N, Valentine M, Miller B, Wong P, Petrucelli L, Kim H, Gao F, Taylor J
Nature, 2015;525(7567):129-33.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
V-myc immortalizes human neural stem cells in the absence of pluripotency-associated traits.
Authors: Pino-Barrio M, Garcia-Garcia E, Menendez P, Martinez-Serrano A
PLoS ONE, 2015;10(3):e0118499.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
beta-Catenin and NF-kappaB co-activation triggered by TLR3 stimulation facilitates stem cell-like phenotypes in breast cancer.
Authors: Jia D, Yang W, Li L, Liu H, Tan Y, Ooi S, Chi L, Filion L, Figeys D, Wang L
Cell Death Differ, 2015;22(2):298-310.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot -
Metabolic rescue in pluripotent cells from patients with mtDNA disease.
Authors: Ma H, Folmes C, Wu J, Morey R, Mora-Castilla S, Ocampo A, Ma L, Poulton J, Wang X, Ahmed R, Kang E, Lee Y, Hayama T, Li Y, Van Dyken C, Gutierrez N, Tippner-Hedges R, Koski A, Mitalipov N, Amato P, Wolf D, Huang T, Terzic A, Laurent L, Izpisua Belmonte J, Mitalipov S
Nature, 2015;524(7564):234-8.
Species: Human
Sample Types: Whole Cells
Applications: IHC -
A multiplex high-throughput gene expression assay to simultaneously detect disease and functional markers in induced pluripotent stem cell-derived retinal pigment epithelium.
Authors: Ferrer M, Corneo B, Davis J, Wan Q, Miyagishima K, King R, Maminishkis A, Marugan J, Sharma R, Shure M, Temple S, Miller S, Bharti K
Stem Cells Transl Med, 2014;3(8):911-22.
Species: Human
Sample Types: Whole Cells
Applications: IHC-Fr -
Sox2 promotes tamoxifen resistance in breast cancer cells.
Authors: Piva M, Domenici G, Iriondo O, Rabano M, Simoes B, Comaills V, Barredo I, Lopez-Ruiz J, Zabalza I, Kypta R, Vivanco M
EMBO Mol Med, 2014;6(1):66-79.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot -
Directed differentiation of patient-specific induced pluripotent stem cells identifies the transcriptional repression and epigenetic modification of NKX2-5, HAND1, and NOTCH1 in hypoplastic left heart syndrome.
Authors: Kobayashi, Junko, Yoshida, Masashi, Tarui, Suguru, Hirata, Masataka, Nagai, Yusuke, Kasahara, Shingo, Naruse, Keiji, Ito, Hiroshi, Sano, Shunji, Oh, Hidemasa
PLoS ONE, 2014;9(7):e102796.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Morphological differences of primary cilia between human induced pluripotent stem cells and their parental somatic cells.
Authors: Nathwani B, Miller C, Yang T, Solimano J, Liao J
Stem Cells Dev, 2014;23(2):115-23.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Characterization and molecular profiling of PSEN1 familial Alzheimer's disease iPSC-derived neural progenitors.
Authors: Sproul A, Jacob S, Pre D, Kim S, Nestor M, Navarro-Sobrino M, Santa-Maria I, Zimmer M, Aubry S, Steele J, Kahler D, Dranovsky A, Arancio O, Crary J, Gandy S, Noggle S
PLoS ONE, 2014;9(1):e84547.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Efficient generation of integration-free human induced pluripotent stem cells from keratinocytes by simple transfection of episomal vectors.
Authors: Piao Y, Hung S, Lim S, Wong R, Ko M
Stem Cells Transl Med, 2014;3(0):787-791.
-
Cell-autonomous correction of ring chromosomes in human induced pluripotent stem cells.
Authors: Bershteyn, Marina, Hayashi, Yohei, Desachy, Guillaum, Hsiao, Edward C, Sami, Salma, Tsang, Kathryn, Weiss, Lauren A, Kriegstein, Arnold R, Yamanaka, Shinya, Wynshaw-Boris, Anthony
Nature, 2014;507(7490):99-103.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Effects of pulsed electromagnetic field on differentiation of HUES-17 human embryonic stem cell line.
Authors: Wu, Yi-Lin, Ma, Shi-Rong, Peng, Tao, Teng, Zeng-Hui, Liang, Xiang-Ya, Guo, Guo-Zhen, Zhang, Hai-Feng, Li, Kang-Chu
Int J Mol Sci, 2014;15(8):14180-90.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot -
Selective lentiviral gene delivery to CD133-expressing human glioblastoma stem cells.
Authors: Bayin, N Sumru, Modrek, Aram S, Dietrich, August, Lebowitz, Jonathan, Abel, Tobias, Song, Hae-Ri, Schober, Markus, Zagzag, David, Buchholz, Christia, Chao, Moses V, Placantonakis, Dimitris
PLoS ONE, 2014;9(12):e116114.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Epigenetic reprogramming induces the expansion of cord blood stem cells.
Authors: Chaurasia P, Gajzer D, Schaniel C, D'Souza S, Hoffman R
J Clin Invest, 2014;124(6):2378-95.
Species: Human
Sample Types: Cell Lysates
Applications: Immunoprecipitation -
Effects of antioxidants on the quality and genomic stability of induced pluripotent stem cells.
Authors: Luo, Lan, Kawakatsu, Miho, Guo, Chao-Wan, Urata, Yoshishi, Huang, Wen-Jing, Ali, Haytham, Doi, Hanako, Kitajima, Yuriko, Tanaka, Takayuki, Goto, Shinji, Ono, Yusuke, Xin, Hong-Bo, Hamano, Kimikazu, Li, Tao-Shen
Sci Rep, 2014;4(0):3779.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot -
Semaphorin 3A induces mesenchymal-stem-like properties in human periodontal ligament cells.
Authors: Wada, Naohisa, Maeda, Hidefumi, Hasegawa, Daigaku, Gronthos, Stan, Bartold, Peter Ma, Menicanin, Danijela, Fujii, Shinsuke, Yoshida, Shinichi, Tomokiyo, Atsushi, Monnouchi, Satoshi, Akamine, Akifumi
Stem Cells Dev, 2014;23(18):2225-36.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Isogenic human pluripotent stem cell pairs reveal the role of a KCNH2 mutation in long-QT syndrome.
Authors: Bellin, Milena, Casini, Simona, Davis, Richard, D'Aniello, Cristina, Haas, Jessica, Ward-van Oostwaard, Dorien, Tertoolen, Leon G J, Jung, Christia, Elliott, David A, Welling, Andrea, Laugwitz, Karl-Lud, Moretti, Alessand, Mummery, Christin
EMBO J, 2013;32(24):3161-75.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
The disease-specific phenotype in cardiomyocytes derived from induced pluripotent stem cells of two long QT syndrome type 3 patients.
Authors: Fatima A, Kaifeng S, Dittmann S, Xu G, Gupta M, Linke M, Zechner U, Nguemo F, Milting H, Farr M, Hescheler J, Saric T
PLoS ONE, 2013;8(12):e83005.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Efficient generation of human iPSCs by a synthetic self-replicative RNA.
Authors: Yoshioka N, Gros E, Li H, Kumar S, Deacon D, Maron C, Muotri A, Chi N, Fu X, Yu B, Dowdy S
Cell Stem Cell, 2013;13(2):246-54.
Species: Human
Sample Types: Whole Cells
Applications: IHC -
Differential L1 regulation in pluripotent stem cells of humans and apes.
Authors: Marchetto M, Narvaiza I, Denli A, Benner C, Lazzarini T, Nathanson J, Paquola A, Desai K, Herai R, Weitzman M, Yeo G, Muotri A, Gage F
Nature, 2013;503(7477):525-9.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Influence of activin A supplementation during human embryonic stem cell derivation on germ cell differentiation potential.
Authors: Duggal G, Heindryckx B, Warrier S, O'Leary T, Van der Jeught M, Lierman S, Vossaert L, Deroo T, Deforce D, Chuva de Sousa Lopes S, De Sutter P
Stem Cells Dev, 2013;22(23):3141-55.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
A thermoresponsive and chemically defined hydrogel for long-term culture of human embryonic stem cells.
Authors: Zhang R, Mjoseng H, Hoeve M, Bauer N, Pells S, Besseling R, Velugotla S, Tourniaire G, Kishen R, Tsenkina Y, Armit C, Duffy C, Helfen M, Edenhofer F, de Sousa P, Bradley M
Nat Commun, 2013;4(0):1335.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Efficient differentiation of human embryonic and induced pluripotent stem cells into functional astrocytes.
Authors: Emdad L, D'Souza SL, Kothari HP, Qadeer ZA, Germano IM
Stem Cells Dev., 2012;21(3):404-10.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Comparative proteomic analysis of human somatic cells, induced pluripotent stem cells, and embryonic stem cells.
Authors: Kim SY, Kim MJ, Jung H
Stem Cells Dev., 2012;21(8):1272-86.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
The effect of human and mouse fibroblast feeder cells on cardiac differentiation of human pluripotent stem cells.
Authors: Pekkanen-Mattila M, Ojala M, Kerkela E, Rajala K, Skottman H, Aalto-Setala K
Stem Cells Int, 2012;2012(0):875059.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Sox2 expression in breast tumours and activation in breast cancer stem cells.
Authors: Leis O, Eguiara A, Lopez-Arribillaga E, Alberdi MJ, Hernandez-Garcia S, Elorriaga K, Pandiella A, Rezola R, Martin AG
Oncogene, 2012;31(11):1354-65.
Species: Human
Sample Types: Whole Tissue
Applications: IHC -
Generation of corneal epithelial cells from induced pluripotent stem cells derived from human dermal fibroblast and corneal limbal epithelium.
Authors: Hayashi, Ryuhei, Ishikawa, Yuki, Ito, Miyuki, Kageyama, Tomofumi, Takashiba, Kuniko, Fujioka, Tsuyoshi, Tsujikawa, Motokazu, Miyoshi, Hiroyuki, Yamato, Masayuki, Nakamura, Yukio, Nishida, Kohji
PLoS ONE, 2012;7(9):e45435.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
A novel role for an RNA polymerase III subunit POLR3G in regulating pluripotency in human embryonic stem cells.
Authors: Wong RC, Pollan S, Fong H, Ibrahim A, Smith EL, Ho M, Laslett AL, Donovan PJ
Stem Cells, 2011;29(10):1517-27.
Species: Human
Sample Types: Cell Lysates
Applications: ChIP -
CD24: a novel surface marker for PDX1-positive pancreatic progenitors derived from human embryonic stem cells.
Authors: Jiang W, Sui X, Zhang D, Liu M, Ding M, Shi Y, Deng H
Stem Cells, 2011;29(4):609-17.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Activation of pluripotency genes in human fibroblast cells by a novel mRNA based approach.
Authors: Plews JR, Li J, Jones M, Moore HD, Mason C, Andrews PW, Na J
PLoS ONE, 2010;5(12):e14397.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot -
Alginate microcapsule for propagation and directed differentiation of hESCs to definitive endoderm.
Authors: Chayosumrit M, Tuch B, Sidhu K
Biomaterials, 2010;31(3):505-14.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot -
A defined glycosaminoglycan-binding substratum for human pluripotent stem cells.
Authors: Klim JR, Li L, Wrighton PJ
Nat. Methods, 2010;7(12):989-94.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
SIP1 mediates cell-fate decisions between neuroectoderm and mesendoderm in human pluripotent stem cells.
Authors: Chng Z, Teo A, Pedersen RA, Vallier L
Cell Stem Cell, 2010;6(1):59-70.
Species: Human
Sample Types: Cell Lysates
Applications: ChIP -
Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome.
Authors: Carvajal-Vergara X, Sevilla A, D'Souza SL
Nature, 2010;465(7299):808-12.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Automated, scalable culture of human embryonic stem cells in feeder-free conditions.
Authors: Thomas RJ, Anderson D, Chandra A, Smith NM, Young LE, Williams D, Denning C
Biotechnol. Bioeng., 2009;102(6):1636-44.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Adipogenic differentiation of human induced pluripotent stem cells: comparison with that of human embryonic stem cells.
Authors: Taura D, Noguchi M, Sone M, Hosoda K, Mori E, Okada Y, Takahashi K, Homma K, Oyamada N, Inuzuka M, Sonoyama T, Ebihara K, Tamura N, Itoh H, Suemori H, Nakatsuji N, Okano H, Yamanaka S, Nakao K
FEBS Lett., 2009;583(6):1029-33.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
The intracellular distribution of the ES cell totipotent markers OCT4 and Sox2 in adult stem cells differs dramatically according to commercial antibody used.
J. Cell. Biochem., 2009;106(5):867-77.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Vitronectin promotes oligodendrocyte differentiation during neurogenesis of human embryonic stem cells.
Authors: Gil JE, Woo DH, Shim JH, Kim SE, You HJ, Park SH, Paek SH, Kim SK, Kim JH
FEBS Lett., 2009;583(3):561-7.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Induced pluripotent stem cells offer new approach to therapy in thalassemia and sickle cell anemia and option in prenatal diagnosis in genetic diseases.
Authors: Ye L, Chang JC, Lin C, Sun X, Yu J, Kan YW
Proc. Natl. Acad. Sci. U.S.A., 2009;106(24):9826-30.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
High-throughput screening assay for the identification of compounds regulating self-renewal and differentiation in human embryonic stem cells.
Authors: Desbordes SC, Placantonakis DG, Ciro A, Socci ND, Lee G, Djaballah H, Studer L
Cell Stem Cell, 2008;2(6):602-12.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Induction of pluripotent stem cells from adult human fibroblasts by defined factors.
Authors: Takahashi K, Tanabe K, Ohnuki M, Narita M, Ichisaka T, Tomoda K, Yamanaka S
Cell, 2007;131(5):861-72.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot -
Pedigreed primate embryonic stem cells express homogeneous familial gene profiles.
Authors: Navara CS, Mich-Basso JD, Redinger CJ, Ben-Yehudah A, Jacoby E, Kovkarova-Naumovski E, Sukhwani M, Orwig K, Kaminski N, Castro CA, Simerly CR, Schatten G
Stem Cells, 2007;25(11):2695-704.
Species: Primate - Macaca mulatta (Rhesus Macaque)
Sample Types: Whole Cells
Applications: ICC -
Isolation of a novel population of multipotent adult stem cells from human hair follicles.
Authors: Yu H, Fang D, Kumar SM, Li L, Nguyen TK, Acs G, Herlyn M, Xu X
Am. J. Pathol., 2006;168(6):1879-88.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Clonal amniotic fluid-derived stem cells express characteristics of both mesenchymal and neural stem cells.
Authors: Tsai MS, Hwang SM, Tsai YL, Cheng FC, Lee JL, Chang YJ
Biol. Reprod., 2005;74(3):545-51.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Monitoring differentiation of human embryonic stem cells using real-time PCR.
Authors: Noaksson K, Zoric N, Zeng X, Rao MS, Hyllner J, Semb H, Kubista M, Sartipy P
Stem Cells, 2005;23(10):1460-7.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Downregulation of NANOG induces differentiation of human embryonic stem cells to extraembryonic lineages.
Authors: Hyslop L, Stojkovic M, Armstrong L, Walter T, Stojkovic P, Przyborski S, Herbert M, Murdoch A, Strachan T, Lako M
Stem Cells, 2005;23(8):1035-43.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot -
Human-Induced Pluripotent Stem Cells Manufactured Using a Current Good Manufacturing Practice-Compliant Process Differentiate Into Clinically Relevant Cells From Three Germ Layers.
Authors: Shafa M, Yang F, Fellner T, Rao M, Baghbaderani B
Front Med (Lausanne), 0;5(0):69.
Species: Human
Sample Types: Whole Cells
Applications: ICC
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Works nicely in immunostainings 1:50.
Works nicely in Western blotting 1:5000.