Human Pro-BMP‑2 Antibody
Human Pro-BMP‑2 Antibody Summary
Ala22-Lys281 (Arg245Ser, Arg279Ser)
Accession # P12643
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Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
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Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: BMP-2
BMP-2, a member of the transforming growth factor beta (TGF-beta ) superfamily, is synthesized as an inactive precursor protein. The N-terminal pro region is removed via proteolytic cleavage to liberate a free 114 amino acid C-terminal fragment that forms a disulfide-linked active BMP-2 homodimer. BMP-2 modulates growth and differentiation of many cell types through its interaction with heterodimeric receptors composed of BMPR-II complexed with BMPR-IA or -IB.
Product Datasheets
Citations for Human Pro-BMP‑2 Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Citations: Showing 1 - 2
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Expression of BMP-2 in Vascular Endothelial Cells of Recipient May Predict Delayed Graft Function After Renal Transplantation
Authors: Bojan Jelakovic
Kidney Blood Press. Res., 2016;41(6):781-793.
Species: Human
Sample Types: Whole Tissue
Applications: IHC-P -
Targeting of bone morphogenetic protein growth factor complexes to fibrillin.
Authors: Sengle G, Charbonneau NL, Ono RN, Sasaki T, Alvarez J, Keene DR, Bachinger HP, Sakai LY
J. Biol. Chem., 2008;283(20):13874-88.
Species: Human
Sample Types: Recombinant Protein
Applications: Western Blot
FAQs
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Reconstitution Buffers
Secondary Antibodies
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Average Rating: 5 (Based on 1 Review)
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