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Endoglin/CD105: Products
Endoglin (CD105) is a transmembrane type III receptor for TGF-beta superfamily ligands and plays an important role in smooth muscle differentiation, angiogenesis, and neovascularization. It is highly expressed on proliferating vascular endothelial cells, chondrocytes, and syncytiotrophoblasts of term placenta. Human Endoglin haploinsufficiency can a cause the vascular disorder, hereditary hemorrhagic telangiectasia type I. Elevated levels of anti-angiogenic soluble Endoglin contribute to pathogenicity in preeclampsia. Endoglin associates with the receptors TGF-beta RII, Activin RIIA or RIIB, BMPR-IA/ALK-3, or BMPR-IB/ALK6 and enhance binding of Activin A, BMP-2, -7, -9, TGF-beta 1, or TGF-beta 3. Endoglin can either enhance or inhibit signaling through these receptor complexes.
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"Endoglin/CD105" has 49 results in Products.
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Simple Plex Human Endoglin/CD105 Cartridge
Simple Plex Human Endoglin/CD105 assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.
Proteome Profiler Human XL Cytokine Array Kit
Contains 4 membranes - each spotted in duplicate with 105 different cytokine antibodies
Proteome Profiler Human Angiogenesis Array Kit
Contains 4 membranes - each spotted in duplicate with 55 different angiogenesis antibodies
Proteome Profiler Mouse XL Cytokine Array
Contains 4 membranes-each spotted in duplicate with 111 different cytokine antibodies
Simple Plex Control for Human Endoglin/CD105
Control for use with Human Endoglin/CD105 Simple Plex Cartridge Kit
Custom Simple Plex™ Assay Panels
Build your own multi-plex biomarker immunoassay panel for Ella™. Highly precise and reproducible. Choose from more than 250 fully validated target analytes.
Proteome Profiler Human XL Oncology Array
Contains 4 membranes-each spotted in duplicate with 84 different cancer-related antibodies
Proteome Profiler Human sReceptor Array, Non-hematopoietic
Contains 4 membranes - 2 spotted in duplicate with 62 different non-hematopoietic antibodies and 2 spotted in duplicate with 57 common antibodies
Recombinant Human Endoglin/CD105 Protein
A New rh Endoglin is Available! It has ~100 fold better TGFbRI binding activity and has a Fc tag!
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