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18 results for "mGluR5 Small Molecules and Peptides" in Products
mGluR5 Small Molecules and Peptides
Human metabotropic glutamate receptor 5 (mGluR5; also mGluR5b) is a 150 kDa, 7-transmembrane glycoprotein that belongs to group I of the C-family of G-protein coupled receptors. mGluR5 is constitutively expressed and regulates neuronal ion channel activity. Human mGluR5 is 1212 amino acids (aa) in length and contains an extracellular domain (ECD) of 558 amino acids. Through its ECD, mGluR5 either homodimerizes or heterodimerizes with the Ca2+-sensor receptor. There is one alternate splice form (mGluR5a) that shows a 32 aa deletion between aa 877 - 908 in the cytoplasmic tail. Over aa 19 - 509, human mGluR5 is 98% aa identical to mouse, rat, and canine mGluR5.
| Chemical Name: | 2-Methyl-6-(phenylethynyl)pyridine hydrochloride |
| Purity: | ≥98% |
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| Chemical Name: | (RS)-2-Chloro-5-hydroxyphenylglycine sodium salt |
| Purity: | ≥99% |
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| Chemical Name: | (L)-(+)-α-Amino-3,5-dioxo-1,2,4-oxadiazolidine-2-propanoic acid |
| Purity: | ≥99% |
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| Chemical Name: | (RS)-2-Chloro-5-hydroxyphenylglycine |
| Purity: | ≥99% |
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| Chemical Name: | N-(3-Chlorophenyl)-N'-(4,5-dihydro-1-methyl-4-oxo-1H-imidazol-2-yl)urea |
| Purity: | ≥98% |
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| Chemical Name: | N-tricyclo[3.3.1.13,7]dec-1-yl-2-quinoxalinecarboxamide |
| Purity: | ≥98% |
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| Chemical Name: | N-Phenyl-7-(hydroxyimino)cyclopropa[b]chromen-1a-carboxamide |
| Purity: | ≥98% |
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| Chemical Name: | 3-((2-Methyl-1,3-thiazol-4-yl)ethynyl)pyridine hydrochloride |
| Purity: | ≥98% |
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| Chemical Name: | 3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide |
| Purity: | ≥98% |
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| Alternate Names: | Topamax |
| Chemical Name: | 2,3:4,5-Bis-O-(1-methylethylidene)-β-D-fructopyranose sulfamate |
| Purity: | ≥98% |
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| Alternate Names: | GP 47779 |
| Chemical Name: | 10,11-Dihydro-10-hydroxy-5H-dibenz(Z)[b,f]azepin-5-carboxamide |
| Purity: | ≥98% |
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| Chemical Name: | N-Cyclobutyl-6-[2-(3-fluorophenyl)ethynyl]-3-pyridinecarboxamide hydrochloride |
| Purity: | ≥98% |
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| Chemical Name: | (9H-Xanthen-9-ylcarbonyl)-carbamic acid butyl ester |
| Purity: | ≥98% |
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| Alternate Names: | Raseglurant |
| Chemical Name: | 2-[(3-Fluorophenyl)ethynyl]-4,6-dimethyl-3-pyridinamine hydrochloride |
| Purity: | ≥98% |
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| Chemical Name: | N-(1-Methylethyl)-5-[2-(4-pyridinyl)ethynyl]-2-pyridinecarboxamide |
| Purity: | ≥98% |
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| Chemical Name: | 3-Fluoro-5-[3-(5-fluoro-2-pyridinyl)-1,2,4-oxadiazol-5-yl]benzonitrile |
| Purity: | ≥98% |
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| Chemical Name: | 4-[5-[(1R)-1-[5-(3-Chlorophenyl)-3-isoxazolyl]ethoxy]-4-methyl-4H-1,2,4-triazol-3-yl]pyridine |
| Purity: | ≥98% |
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| Alternate Names: | JNJ 46778212 |
| Chemical Name: | [6,7-Dihydro-2-(phenoxymethyl)oxazolo[5,4-c]pyridin-5(4H)-yl](fluorophenyl)methanone |
| Purity: | ≥98% |
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